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The map label for this gene is pgsA2 [H]

Identifier: 15606274

GI number: 15606274

Start: 658313

End: 659230

Strand: Direct

Name: pgsA2 [H]

Synonym: aq_958

Alternate gene names: 15606274

Gene position: 658313-659230 (Clockwise)

Preceding gene: 15606273

Following gene: 15606280

Centisome position: 42.44

GC content: 45.75

Gene sequence:

>918_bases
ATGGAAAATTTCCTCAGCTTCTTCAGGATACTGATAACCTTTCCGGTAGTCTTTCTTATACTGGAGAAAGAATTTTTCCT
CGCCTTCTGGCTTTATTTGGTAGGAGCTCTGACCGACTGGTTTGACGGAAACCTTGCGAGAAAGAATAAAAGAGTTTCAA
ACTTTGGGAAACTCCTCGATCCTTACGCGGATAAGGTTTTTGTCCTGCTTCCCTTAATAGCCCTCGTAGAGGTAAAGAAG
GTAAAGGCAATCTGGGTAATACTCCTTACATTCAGGGAACTGAGTATTTCCTTTTTCAGGAGCGTTATGGTAGAAAAGGG
GATTTACATGGAAGCAAGCTTCACGGGAAAGCTGAAAGCCTTTCTTGAGTTCAGCGCTATATCCCTCATACTCCTCGGTG
TTGAGCTCGGGAATTACCTTTTGATCCTCGCCGTGATATTTGCCTACATCTCCGCTTCGGGTACCTCAAAAGGTTCTGGG
CTCTCATTTAAAGAACTTGTTCGTTACGGGCATCCTCCAGTCCTTTCCGAAAGCCCTGCTCGTGATCTTTGGTCCGATGG
GTGCCTGCTTTCTCTTGTACTCGTTTTTCCTTATCATGTTTATGGTCTTGTACACCGCATCCCTCGGAAGTCCTTTCCTG
ATTATCTCTTCAGGGCTCAAGTTCTCCTCTATGTAAAGCATGAGTATTTGATCCAGTATCTCGTAAGGCGGGAGTACGTC
CTGATCTGTCTGATTTGGTCTGAGCTCCGCCGAAGGCGGTTTTTTAAACACTCTTTCGGGAATATCGGGGCTTATGGAGT
TTCTGTACCTTGCGAGTTTGTAAACCCACGTTTTGTAAACGTCTTTTATCGGGGCAAAACCTCCCGCCATGTCCCCGTAT
ATGGTTGTGTAGCCCACTGCCGTTTCACTCTTGTTTGA

Upstream 100 bases:

>100_bases
GGAAAGGATTTCCTTAAAAGGAAAGAGGAGAGAGGGTTTTTGTGAAGGAAACGGACTCGTGTGTATGTGTACGGTGTTGC
TCGTTAAAATGTAAATACCC

Downstream 100 bases:

>100_bases
AGTGGAAAGAACGAGATAACGGAACTTATTTGAAAAGTAAAAGAGGATGTTTGCCCTTATGCGTGCCTGTATGTTTTCGT
CGGCAACGTCAAAGGTAATT

Product: phosphotidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MENFLSFFRILITFPVVFLILEKEFFLAFWLYLVGALTDWFDGNLARKNKRVSNFGKLLDPYADKVFVLLPLIALVEVKK
VKAIWVILLTFRELSISFFRSVMVEKGIYMEASFTGKLKAFLEFSAISLILLGVELGNYLLILAVIFAYISASGTSKGSG
LSFKELVRYGHPPVLSESPARDLWSDGCLLSLVLVFPYHVYGLVHRIPRKSFPDYLFRAQVLLYVKHEYLIQYLVRREYV
LICLIWSELRRRRFFKHSFGNIGAYGVSVPCEFVNPRFVNVFYRGKTSRHVPVYGCVAHCRFTLV

Sequences:

>Translated_305_residues
MENFLSFFRILITFPVVFLILEKEFFLAFWLYLVGALTDWFDGNLARKNKRVSNFGKLLDPYADKVFVLLPLIALVEVKK
VKAIWVILLTFRELSISFFRSVMVEKGIYMEASFTGKLKAFLEFSAISLILLGVELGNYLLILAVIFAYISASGTSKGSG
LSFKELVRYGHPPVLSESPARDLWSDGCLLSLVLVFPYHVYGLVHRIPRKSFPDYLFRAQVLLYVKHEYLIQYLVRREYV
LICLIWSELRRRRFFKHSFGNIGAYGVSVPCEFVNPRFVNVFYRGKTSRHVPVYGCVAHCRFTLV
>Mature_305_residues
MENFLSFFRILITFPVVFLILEKEFFLAFWLYLVGALTDWFDGNLARKNKRVSNFGKLLDPYADKVFVLLPLIALVEVKK
VKAIWVILLTFRELSISFFRSVMVEKGIYMEASFTGKLKAFLEFSAISLILLGVELGNYLLILAVIFAYISASGTSKGSG
LSFKELVRYGHPPVLSESPARDLWSDGCLLSLVLVFPYHVYGLVHRIPRKSFPDYLFRAQVLLYVKHEYLIQYLVRREYV
LICLIWSELRRRRFFKHSFGNIGAYGVSVPCEFVNPRFVNVFYRGKTSRHVPVYGCVAHCRFTLV

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=140, Percent_Identity=35.7142857142857, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 35265; Mature: 35265

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENFLSFFRILITFPVVFLILEKEFFLAFWLYLVGALTDWFDGNLARKNKRVSNFGKLLD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PYADKVFVLLPLIALVEVKKVKAIWVILLTFRELSISFFRSVMVEKGIYMEASFTGKLKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHH
FLEFSAISLILLGVELGNYLLILAVIFAYISASGTSKGSGLSFKELVRYGHPPVLSESPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCC
RDLWSDGCLLSLVLVFPYHVYGLVHRIPRKSFPDYLFRAQVLLYVKHEYLIQYLVRREYV
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LICLIWSELRRRRFFKHSFGNIGAYGVSVPCEFVNPRFVNVFYRGKTSRHVPVYGCVAHC
HHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHCCCEEEEEEEECCCCCCCCHHHHHHHH
RFTLV
HEECC
>Mature Secondary Structure
MENFLSFFRILITFPVVFLILEKEFFLAFWLYLVGALTDWFDGNLARKNKRVSNFGKLLD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PYADKVFVLLPLIALVEVKKVKAIWVILLTFRELSISFFRSVMVEKGIYMEASFTGKLKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHH
FLEFSAISLILLGVELGNYLLILAVIFAYISASGTSKGSGLSFKELVRYGHPPVLSESPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCC
RDLWSDGCLLSLVLVFPYHVYGLVHRIPRKSFPDYLFRAQVLLYVKHEYLIQYLVRREYV
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LICLIWSELRRRRFFKHSFGNIGAYGVSVPCEFVNPRFVNVFYRGKTSRHVPVYGCVAHC
HHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHCCCEEEEEEEECCCCCCCCHHHHHHHH
RFTLV
HEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA