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The map label for this gene is argS

Identifier: 15606252

GI number: 15606252

Start: 637841

End: 639592

Strand: Direct

Name: argS

Synonym: aq_923

Alternate gene names: 15606252

Gene position: 637841-639592 (Clockwise)

Preceding gene: 15606248

Following gene: 15606253

Centisome position: 41.12

GC content: 43.84

Gene sequence:

>1752_bases
ATGAAAGAACTCGTAAAGGAGAAAGTCCTTAAGGCTTTAAAGGAACTCTACAACACACAGGTGGAAAACTTCAAGGTTGA
AAAGCCAAAGGAAGAAGCCCACGGAGACCTCGCCTCGAATGTAGCGTTCCTGCTTGCAAGAGAACTAAAAAAACCTCCCG
TAAATATAGCCCAGGAGCTAGCGGATTTCTTATCAAAAGACGAGACTTTCAAAAGCGTTGAGGCGGTAAAAGGTTTTATA
AACTTCCGTTTCTCCGAAGATTTCTTAAAAGAAGAGTTTAAAAAGTTCCTCCTCAGCGGAGAGGCATACTTCAAAGAAGA
CTTAGGAAAGGGTTTAAAGGTTCAACTTGAGTACGTGAGTGCGAATCCCACGGGTCCGCTTCATTTAGGACACGGCAGGG
GTGCGGTGGTCGGAGATACACTCGCAAGGCTTTTTAAGTTCTTCAATTACGACGTTACGAGAGAGTACTACATAAACGAC
GCGGGAAGGCAAGTTTACCTCCTCGGTATCTCTATATATTACAGATACTTAGAAAAGTGCCCTGAAAGGGACGAAGAAAC
CTTTAAAGAAATAAAAGAGATATTTGAAAAAGACGGATACAGGGGGGAGTACGTAAAGGAAATCGCGGAAAGGCTAAGAA
AACTAGTAGGGGAAAGTCTCTGCAAACCCGAAGAAGCAAACCTGAAGGAAGTAAGGGAAAAGATTTTAAAAGAGGAAAGT
ATTGAACTCTACTACACGAAGAAGTACGAACCGAAGGACGTTGTTGACCTCCTCTCTAACTACGGACTTGACCTCATGAT
GAAAGAGATAAGGGAGGATCTATCCTTAATGGACATTTCCTTTGACGTCTGGTTCAGTGAAAGGAGTCTATACGACAGTG
GAGAAGTGGAGAGACTAATAAACCTTTTAAAGGAAAAGGGATACGTTTACGAGAAAGACGGGGCACTCTGGCTGAAGACT
TCCCTTTTCGGGGACGATAAAGACAGGGTTGTGAAACGTTCGGACGGCACATACACTTACTTTGCCTCGGACATAGCTTA
CCACTACAACAAGTTCAAAAGGGGCTTTGAAAAAGTTATAAACGTCTGGGGAGCGGACCACCACGGATACATCCCTAGGG
TAAAAGCAGCCCTTAAAATGCTGGAAATTCCAGAAGACTGGCTTGAAATCCTGCTTGTCCAGATGGTGAAACTCTTCAGG
GAAGGAAAGGAAGTTAAGATGTCAAAAAGGGCGGGAACTTTCGTAACCTTGAGAGAGCTACTTGATGAGGTAGGAAAAGA
CGCTGTGAGGTTTATATTCCTTACAAAGAGAAGTGACACGCCCCTTGACTTTGACGTTGAAAAGGCAAAAGAAAAGAGTT
CCGAAAACCCCGTTTACTACGTACAGTACGCGCACGCAAGAATTTCGGGGATATTCAGGGAGTTTAAGGAAAGGTATAAA
AAAGACGTATCCGTGGAGGAGTTAATAAACTACGTTCAGCACTTGGAAGAAGAGGCTGAAATAAAACTCATAAAGAAGGT
TCTATTTTTCAAAGACGAACTCGTTGACATAACCTTAAAGAGGGAGCCTCACCTCCTTACCTACTACCTGATAGACCTTG
CCGGGGATTTTCACCACTACTACAACCACCACAGGATACTGGGAATGGAGGAAAACGTTATGTTTTCAAGACTGGCTCTC
GTGAAGGGCATAAAGGAAGTGGTAAGACTGGGGCTCAACCTCATGGGAGTAAGTGCTCCAGAGAGGATGTAA

Upstream 100 bases:

>100_bases
AGCGAGCGTGCAAACCTGTAAGGGTAGTGCTTTGTCTCCGAGTGATAAAAGAGAACCTCCCTGAAGTCTCCCACACCTAC
AAGTATAAAATAAAGTTCCT

Downstream 100 bases:

>100_bases
TTGTGAGATAATTTCTCTCATGCGCAGTGACGGAAGAAAAGAGGATCAACTCAGACCAGTAAGTATTCAGAGAGACTTTC
TTGAATATCCGGAAGGTTCG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MKELVKEKVLKALKELYNTQVENFKVEKPKEEAHGDLASNVAFLLARELKKPPVNIAQELADFLSKDETFKSVEAVKGFI
NFRFSEDFLKEEFKKFLLSGEAYFKEDLGKGLKVQLEYVSANPTGPLHLGHGRGAVVGDTLARLFKFFNYDVTREYYIND
AGRQVYLLGISIYYRYLEKCPERDEETFKEIKEIFEKDGYRGEYVKEIAERLRKLVGESLCKPEEANLKEVREKILKEES
IELYYTKKYEPKDVVDLLSNYGLDLMMKEIREDLSLMDISFDVWFSERSLYDSGEVERLINLLKEKGYVYEKDGALWLKT
SLFGDDKDRVVKRSDGTYTYFASDIAYHYNKFKRGFEKVINVWGADHHGYIPRVKAALKMLEIPEDWLEILLVQMVKLFR
EGKEVKMSKRAGTFVTLRELLDEVGKDAVRFIFLTKRSDTPLDFDVEKAKEKSSENPVYYVQYAHARISGIFREFKERYK
KDVSVEELINYVQHLEEEAEIKLIKKVLFFKDELVDITLKREPHLLTYYLIDLAGDFHHYYNHHRILGMEENVMFSRLAL
VKGIKEVVRLGLNLMGVSAPERM

Sequences:

>Translated_583_residues
MKELVKEKVLKALKELYNTQVENFKVEKPKEEAHGDLASNVAFLLARELKKPPVNIAQELADFLSKDETFKSVEAVKGFI
NFRFSEDFLKEEFKKFLLSGEAYFKEDLGKGLKVQLEYVSANPTGPLHLGHGRGAVVGDTLARLFKFFNYDVTREYYIND
AGRQVYLLGISIYYRYLEKCPERDEETFKEIKEIFEKDGYRGEYVKEIAERLRKLVGESLCKPEEANLKEVREKILKEES
IELYYTKKYEPKDVVDLLSNYGLDLMMKEIREDLSLMDISFDVWFSERSLYDSGEVERLINLLKEKGYVYEKDGALWLKT
SLFGDDKDRVVKRSDGTYTYFASDIAYHYNKFKRGFEKVINVWGADHHGYIPRVKAALKMLEIPEDWLEILLVQMVKLFR
EGKEVKMSKRAGTFVTLRELLDEVGKDAVRFIFLTKRSDTPLDFDVEKAKEKSSENPVYYVQYAHARISGIFREFKERYK
KDVSVEELINYVQHLEEEAEIKLIKKVLFFKDELVDITLKREPHLLTYYLIDLAGDFHHYYNHHRILGMEENVMFSRLAL
VKGIKEVVRLGLNLMGVSAPERM
>Mature_583_residues
MKELVKEKVLKALKELYNTQVENFKVEKPKEEAHGDLASNVAFLLARELKKPPVNIAQELADFLSKDETFKSVEAVKGFI
NFRFSEDFLKEEFKKFLLSGEAYFKEDLGKGLKVQLEYVSANPTGPLHLGHGRGAVVGDTLARLFKFFNYDVTREYYIND
AGRQVYLLGISIYYRYLEKCPERDEETFKEIKEIFEKDGYRGEYVKEIAERLRKLVGESLCKPEEANLKEVREKILKEES
IELYYTKKYEPKDVVDLLSNYGLDLMMKEIREDLSLMDISFDVWFSERSLYDSGEVERLINLLKEKGYVYEKDGALWLKT
SLFGDDKDRVVKRSDGTYTYFASDIAYHYNKFKRGFEKVINVWGADHHGYIPRVKAALKMLEIPEDWLEILLVQMVKLFR
EGKEVKMSKRAGTFVTLRELLDEVGKDAVRFIFLTKRSDTPLDFDVEKAKEKSSENPVYYVQYAHARISGIFREFKERYK
KDVSVEELINYVQHLEEEAEIKLIKKVLFFKDELVDITLKREPHLLTYYLIDLAGDFHHYYNHHRILGMEENVMFSRLAL
VKGIKEVVRLGLNLMGVSAPERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=612, Percent_Identity=23.6928104575163, Blast_Score=93, Evalue=7e-19,
Organism=Escherichia coli, GI1788184, Length=638, Percent_Identity=25.0783699059561, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71985061, Length=613, Percent_Identity=24.6329526916803, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71985068, Length=573, Percent_Identity=24.956369982548, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320548, Length=573, Percent_Identity=25.4799301919721, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6321883, Length=566, Percent_Identity=23.321554770318, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_AQUAE (O67068)

Other databases:

- EMBL:   AE000657
- PIR:   A70380
- RefSeq:   NP_213630.1
- ProteinModelPortal:   O67068
- GeneID:   1193610
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_923
- NMPDR:   fig|224324.1.peg.645
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   CLSK2748384
- BioCyc:   AAEO224324:AQ_923-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 68320; Mature: 68320

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELVKEKVLKALKELYNTQVENFKVEKPKEEAHGDLASNVAFLLARELKKPPVNIAQEL
CHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHH
ADFLSKDETFKSVEAVKGFINFRFSEDFLKEEFKKFLLSGEAYFKEDLGKGLKVQLEYVS
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEEEE
ANPTGPLHLGHGRGAVVGDTLARLFKFFNYDVTREYYINDAGRQVYLLGISIYYRYLEKC
CCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHC
PERDEETFKEIKEIFEKDGYRGEYVKEIAERLRKLVGESLCKPEEANLKEVREKILKEES
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
IELYYTKKYEPKDVVDLLSNYGLDLMMKEIREDLSLMDISFDVWFSERSLYDSGEVERLI
CEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHHH
NLLKEKGYVYEKDGALWLKTSLFGDDKDRVVKRSDGTYTYFASDIAYHYNKFKRGFEKVI
HHHHHCCCEEECCCCEEEEEECCCCCHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHH
NVWGADHHGYIPRVKAALKMLEIPEDWLEILLVQMVKLFREGKEVKMSKRAGTFVTLREL
HHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHH
LDEVGKDAVRFIFLTKRSDTPLDFDVEKAKEKSSENPVYYVQYAHARISGIFREFKERYK
HHHHCHHHEEEEEEECCCCCCCCCCHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
KDVSVEELINYVQHLEEEAEIKLIKKVLFFKDELVDITLKREPHLLTYYLIDLAGDFHHY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEHHHHHHHHHHHHH
YNHHRILGMEENVMFSRLALVKGIKEVVRLGLNLMGVSAPERM
HCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCC
>Mature Secondary Structure
MKELVKEKVLKALKELYNTQVENFKVEKPKEEAHGDLASNVAFLLARELKKPPVNIAQEL
CHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHH
ADFLSKDETFKSVEAVKGFINFRFSEDFLKEEFKKFLLSGEAYFKEDLGKGLKVQLEYVS
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEEEE
ANPTGPLHLGHGRGAVVGDTLARLFKFFNYDVTREYYINDAGRQVYLLGISIYYRYLEKC
CCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHC
PERDEETFKEIKEIFEKDGYRGEYVKEIAERLRKLVGESLCKPEEANLKEVREKILKEES
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
IELYYTKKYEPKDVVDLLSNYGLDLMMKEIREDLSLMDISFDVWFSERSLYDSGEVERLI
CEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHHH
NLLKEKGYVYEKDGALWLKTSLFGDDKDRVVKRSDGTYTYFASDIAYHYNKFKRGFEKVI
HHHHHCCCEEECCCCEEEEEECCCCCHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHH
NVWGADHHGYIPRVKAALKMLEIPEDWLEILLVQMVKLFREGKEVKMSKRAGTFVTLREL
HHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHH
LDEVGKDAVRFIFLTKRSDTPLDFDVEKAKEKSSENPVYYVQYAHARISGIFREFKERYK
HHHHCHHHEEEEEEECCCCCCCCCCHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
KDVSVEELINYVQHLEEEAEIKLIKKVLFFKDELVDITLKREPHLLTYYLIDLAGDFHHY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEHHHHHHHHHHHHH
YNHHRILGMEENVMFSRLALVKGIKEVVRLGLNLMGVSAPERM
HCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320