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The map label for this gene is tly [H]

Identifier: 15606155

GI number: 15606155

Start: 534837

End: 535613

Strand: Direct

Name: tly [H]

Synonym: aq_773

Alternate gene names: 15606155

Gene position: 534837-535613 (Clockwise)

Preceding gene: 15606154

Following gene: 15606156

Centisome position: 34.48

GC content: 45.69

Gene sequence:

>777_bases
ATGAGGCTTGACAAGTATTTGACCGACAAGGGTATAGTCCCCTCACGGGAAAAGGCACAGGCGGTAATAATGGCGGGACA
GGTGCTCGTAAACGGAAAAGTAGTTGACAAACCCGGATACAGATTAAAGGGGAACGAAAAGGTAGAGGTAAAGGAACTCC
CCAAATACGTTTCCAGAGGCGGGGAAAAACTTGAATGGGCGATAAAGAGGTTTTCCTTAGATTTAAAGGATAAAGTCGTT
CTGGACGTTGGTTCTTCCACAGGAGGCTTTACGGACTGCGCCCTTCAACACGGGGCGAAAAAGGTTTACGCGGTAGACGT
CGGAAGGGGACAAATGGACTACAAACTAAGGCAGGACCCGAGAGTAGTACTCTATGAGGAAACGGACGCAAGAGAACTCT
CAGAAGAACACGTTCCCGAAAAGGTTGACCTCATAACCTGTGACGTTTCCTTTATATCCTCCACGAAAGTTCTTCCAAAC
GTATTTAAGTTCTTAAAAGAAGACGGACTCCTTTTAGTTCTTGTAAAGCCCCAGTTTGAACTCTGTCCGAGGAAAGTAAA
AAAGGGAGTAGTCAGGGAAAAAGAACACAAGAGGGAAGCCCTGCAAAAGGTAGTAAACTTCCTAAAAGAGAACGGCTTTA
GAATACTCGGAGTTATAAAGTCAAAGCCGAAGGGCACTAAGGGAAATGAGGAATTTTTCGTTTTGGCTGGGAGAAAAGGG
GAGGAAGTAAACTTATCCGAGGCGATAGAGAAAGCCCTTGAGGAGGTAGTGGATTGA

Upstream 100 bases:

>100_bases
GGAACAAAATTCCCGACTTTTCCGAGTACACGGTTGAAGTCAAAGCTGAGATTGACAAGATAAAGCAACAGGCTGCAAAC
GTGGAATAACTTTTATCCTT

Downstream 100 bases:

>100_bases
GGCGTTTTTTAATCCTCCTGTACGTGTTCCTTGTAAGTTCAGTTCTCGGCTTTATAGCCTTTGAGATATTCACACCCCTT
TACGTTCCAAAGAAAACCGT

Product: hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MRLDKYLTDKGIVPSREKAQAVIMAGQVLVNGKVVDKPGYRLKGNEKVEVKELPKYVSRGGEKLEWAIKRFSLDLKDKVV
LDVGSSTGGFTDCALQHGAKKVYAVDVGRGQMDYKLRQDPRVVLYEETDARELSEEHVPEKVDLITCDVSFISSTKVLPN
VFKFLKEDGLLLVLVKPQFELCPRKVKKGVVREKEHKREALQKVVNFLKENGFRILGVIKSKPKGTKGNEEFFVLAGRKG
EEVNLSEAIEKALEEVVD

Sequences:

>Translated_258_residues
MRLDKYLTDKGIVPSREKAQAVIMAGQVLVNGKVVDKPGYRLKGNEKVEVKELPKYVSRGGEKLEWAIKRFSLDLKDKVV
LDVGSSTGGFTDCALQHGAKKVYAVDVGRGQMDYKLRQDPRVVLYEETDARELSEEHVPEKVDLITCDVSFISSTKVLPN
VFKFLKEDGLLLVLVKPQFELCPRKVKKGVVREKEHKREALQKVVNFLKENGFRILGVIKSKPKGTKGNEEFFVLAGRKG
EEVNLSEAIEKALEEVVD
>Mature_258_residues
MRLDKYLTDKGIVPSREKAQAVIMAGQVLVNGKVVDKPGYRLKGNEKVEVKELPKYVSRGGEKLEWAIKRFSLDLKDKVV
LDVGSSTGGFTDCALQHGAKKVYAVDVGRGQMDYKLRQDPRVVLYEETDARELSEEHVPEKVDLITCDVSFISSTKVLPN
VFKFLKEDGLLLVLVKPQFELCPRKVKKGVVREKEHKREALQKVVNFLKENGFRILGVIKSKPKGTKGNEEFFVLAGRKG
EEVNLSEAIEKALEEVVD

Specific function: Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined [H]

COG id: COG1189

COG function: function code J; Predicted rRNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004538
- InterPro:   IPR002877
- InterPro:   IPR002942 [H]

Pfam domain/function: PF01728 FtsJ; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 29015; Mature: 29015

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50889 S4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDKYLTDKGIVPSREKAQAVIMAGQVLVNGKVVDKPGYRLKGNEKVEVKELPKYVSRG
CCCCHHCCCCCCCCCHHHHHEEEEECEEEECCEEECCCCCEECCCCEECHHHHHHHHHCC
GEKLEWAIKRFSLDLKDKVVLDVGSSTGGFTDCALQHGAKKVYAVDVGRGQMDYKLRQDP
CHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCEEECCCC
RVVLYEETDARELSEEHVPEKVDLITCDVSFISSTKVLPNVFKFLKEDGLLLVLVKPQFE
EEEEEECCCHHHHHHHCCCCEEEEEEEEHHHHCCCHHHHHHHHHHHCCCEEEEEECCCHH
LCPRKVKKGVVREKEHKREALQKVVNFLKENGFRILGVIKSKPKGTKGNEEFFVLAGRKG
HCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEEEECCCC
EEVNLSEAIEKALEEVVD
CCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLDKYLTDKGIVPSREKAQAVIMAGQVLVNGKVVDKPGYRLKGNEKVEVKELPKYVSRG
CCCCHHCCCCCCCCCHHHHHEEEEECEEEECCEEECCCCCEECCCCEECHHHHHHHHHCC
GEKLEWAIKRFSLDLKDKVVLDVGSSTGGFTDCALQHGAKKVYAVDVGRGQMDYKLRQDP
CHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCEEECCCC
RVVLYEETDARELSEEHVPEKVDLITCDVSFISSTKVLPNVFKFLKEDGLLLVLVKPQFE
EEEEEECCCHHHHHHHCCCCEEEEEEEEHHHHCCCHHHHHHHHHHHCCCEEEEEECCCHH
LCPRKVKKGVVREKEHKREALQKVVNFLKENGFRILGVIKSKPKGTKGNEEFFVLAGRKG
HCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEEEECCCC
EEVNLSEAIEKALEEVVD
CCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730486 [H]