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The map label for this gene is ppiD [H]

Identifier: 15606037

GI number: 15606037

Start: 403186

End: 404499

Strand: Direct

Name: ppiD [H]

Synonym: aq_592

Alternate gene names: 15606037

Gene position: 403186-404499 (Clockwise)

Preceding gene: 15606036

Following gene: 15606041

Centisome position: 25.99

GC content: 39.73

Gene sequence:

>1314_bases
ATGTTCGGTCTAATCCAGAAACACAAGAGAATTGCCGTAATAATAGTTACCCTTGCGTCTTTATCCTTCCTCTTCTGGAT
GTTCTCGGTCTCGGACGTAAAGCAGATGCTCACAGGAAATCCTTGTGTCGCAACAGTAGGAGATGAGTGTATAACTCTCA
GGGAGTATAGATTTGAACTCTTAAAGTACTCAAATTTCCTTCAGGACGAAAGAACTGAAAAACTCGCAAGGAGAGTGGCT
TTAAATTCTCTTATCACTAAAGAAGTTTTGTACTTAAAAGCTAAAGAACTCGGCTGGTACGTATCGGATGAGGAAGTTGT
GGAAGTAATTAAAAACGACGAAAACTTCAAAGAAAAGGGTAAGTTTTCCGTGGAGAAGTACAGGGAAACCTTAAATAGAT
TTGGACTAACCCCTGCGGAGTATGAGGAAATCGTAAGGAAAAGCTTAATGGCTCAGAGAGTTTTAAACTTTTTAAGGGAA
GGCGTTTACGTTCTTCCCGACGAACTGGACATTCAGAAAAGGTTTTACTCCCTTCGTGTAGAGGGAAAGCTTTACCTGAT
AAAGCCTTCGGACGTAAAAGTAGATTACGAGCCAAGCGAAGAAGAAATCAAAGAATATTACGAAAAGAATAAGGAAAAGT
TTAAGGAAGAAGAAAAGGAAGTTGTGTACGTCTGGAGCTTAAAAGACAAGGAAAAGGTGAAGGAATACTATGAAAACCTG
AAGAAGGGAAGTATTCCTTCAGGCTACACGGAGTTCAACGAAAATCTCCCGCCAAAAGTTAAGGAAGCAGTAAAGGAACT
CAATCAAGAAAATAGGATAAAAGTGGTAAGAGTAGGCGAGAATTACTACCTCCTTTACTACAAAGGAAAGGAAAATGCTG
GCTACAAACCTCTGGAAGAGGTGAAGGAAGAAATAAAGAAAGAACTCGTAGCTAAAAAACAGAGGGAAAAATTGAAGGAG
TTTGCACAGGAAGTGTTTAAAAACTTGAAAGAAGGGAAAGAAGTCGGGGTAAAACCACTTGCATTCTCTTCCGCAAGCCT
TGAGGAAATACAACGAATACTTATGGTGGAGCAGAAGGATTTACTTAATTTGGTTTTCGGGAAAGAAAAGGTTTATGGAC
CTTACCCTTCGCTTGCGGGGTACGGAATACTGGTAGTTAAAAACAGGAAGTTTGAAGAATTAAAACCTGAGCAGGTAAAG
GAAATTGAAAGGGAACTTAAAGACAACAAGTTTAACGACCTTGCTGGGCTTTTCGTAGAAAAGTTGATAAAAGAGTACGG
AGTGAAAGTGAACGAACAACTGGCAGGGATTTAG

Upstream 100 bases:

>100_bases
GTAGGCGGCGTAGCTCAGCTGGTCAGAGCGGGGATCTCATAAGTCCCAGGTCGGAGGTTCGAGTCCTCCCGCCGCCACCA
AATCCTTTAAAATCTTTCTC

Downstream 100 bases:

>100_bases
TACTTTCTCTCTTCTGGTTTGTACTTTGTTATCCTTACGGGAATGTATTCAAGCTTTAAATTGCCGTTTTTGTCGTAATA
GACGAGGGAGTGTTTTAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MFGLIQKHKRIAVIIVTLASLSFLFWMFSVSDVKQMLTGNPCVATVGDECITLREYRFELLKYSNFLQDERTEKLARRVA
LNSLITKEVLYLKAKELGWYVSDEEVVEVIKNDENFKEKGKFSVEKYRETLNRFGLTPAEYEEIVRKSLMAQRVLNFLRE
GVYVLPDELDIQKRFYSLRVEGKLYLIKPSDVKVDYEPSEEEIKEYYEKNKEKFKEEEKEVVYVWSLKDKEKVKEYYENL
KKGSIPSGYTEFNENLPPKVKEAVKELNQENRIKVVRVGENYYLLYYKGKENAGYKPLEEVKEEIKKELVAKKQREKLKE
FAQEVFKNLKEGKEVGVKPLAFSSASLEEIQRILMVEQKDLLNLVFGKEKVYGPYPSLAGYGILVVKNRKFEELKPEQVK
EIERELKDNKFNDLAGLFVEKLIKEYGVKVNEQLAGI

Sequences:

>Translated_437_residues
MFGLIQKHKRIAVIIVTLASLSFLFWMFSVSDVKQMLTGNPCVATVGDECITLREYRFELLKYSNFLQDERTEKLARRVA
LNSLITKEVLYLKAKELGWYVSDEEVVEVIKNDENFKEKGKFSVEKYRETLNRFGLTPAEYEEIVRKSLMAQRVLNFLRE
GVYVLPDELDIQKRFYSLRVEGKLYLIKPSDVKVDYEPSEEEIKEYYEKNKEKFKEEEKEVVYVWSLKDKEKVKEYYENL
KKGSIPSGYTEFNENLPPKVKEAVKELNQENRIKVVRVGENYYLLYYKGKENAGYKPLEEVKEEIKKELVAKKQREKLKE
FAQEVFKNLKEGKEVGVKPLAFSSASLEEIQRILMVEQKDLLNLVFGKEKVYGPYPSLAGYGILVVKNRKFEELKPEQVK
EIERELKDNKFNDLAGLFVEKLIKEYGVKVNEQLAGI
>Mature_437_residues
MFGLIQKHKRIAVIIVTLASLSFLFWMFSVSDVKQMLTGNPCVATVGDECITLREYRFELLKYSNFLQDERTEKLARRVA
LNSLITKEVLYLKAKELGWYVSDEEVVEVIKNDENFKEKGKFSVEKYRETLNRFGLTPAEYEEIVRKSLMAQRVLNFLRE
GVYVLPDELDIQKRFYSLRVEGKLYLIKPSDVKVDYEPSEEEIKEYYEKNKEKFKEEEKEVVYVWSLKDKEKVKEYYENL
KKGSIPSGYTEFNENLPPKVKEAVKELNQENRIKVVRVGENYYLLYYKGKENAGYKPLEEVKEEIKKELVAKKQREKLKE
FAQEVFKNLKEGKEVGVKPLAFSSASLEEIQRILMVEQKDLLNLVFGKEKVYGPYPSLAGYGILVVKNRKFEELKPEQVK
EIERELKDNKFNDLAGLFVEKLIKEYGVKVNEQLAGI

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=169, Percent_Identity=29.585798816568, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 51312; Mature: 51312

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGLIQKHKRIAVIIVTLASLSFLFWMFSVSDVKQMLTGNPCVATVGDECITLREYRFEL
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHH
LKYSNFLQDERTEKLARRVALNSLITKEVLYLKAKELGWYVSDEEVVEVIKNDENFKEKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHCCCCHHHHC
KFSVEKYRETLNRFGLTPAEYEEIVRKSLMAQRVLNFLREGVYVLPDELDIQKRFYSLRV
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHEEE
EGKLYLIKPSDVKVDYEPSEEEIKEYYEKNKEKFKEEEKEVVYVWSLKDKEKVKEYYENL
CCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHH
KKGSIPSGYTEFNENLPPKVKEAVKELNQENRIKVVRVGENYYLLYYKGKENAGYKPLEE
HCCCCCCCHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCCCCCHHH
VKEEIKKELVAKKQREKLKEFAQEVFKNLKEGKEVGVKPLAFSSASLEEIQRILMVEQKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHH
LLNLVFGKEKVYGPYPSLAGYGILVVKNRKFEELKPEQVKEIERELKDNKFNDLAGLFVE
HHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHCCHHHHHHHHHHHHCCCHHHHHHHHHH
KLIKEYGVKVNEQLAGI
HHHHHHCCCCHHHHCCC
>Mature Secondary Structure
MFGLIQKHKRIAVIIVTLASLSFLFWMFSVSDVKQMLTGNPCVATVGDECITLREYRFEL
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHH
LKYSNFLQDERTEKLARRVALNSLITKEVLYLKAKELGWYVSDEEVVEVIKNDENFKEKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHCCCCHHHHC
KFSVEKYRETLNRFGLTPAEYEEIVRKSLMAQRVLNFLREGVYVLPDELDIQKRFYSLRV
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHEEE
EGKLYLIKPSDVKVDYEPSEEEIKEYYEKNKEKFKEEEKEVVYVWSLKDKEKVKEYYENL
CCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHH
KKGSIPSGYTEFNENLPPKVKEAVKELNQENRIKVVRVGENYYLLYYKGKENAGYKPLEE
HCCCCCCCHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCCCCCHHH
VKEEIKKELVAKKQREKLKEFAQEVFKNLKEGKEVGVKPLAFSSASLEEIQRILMVEQKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHH
LLNLVFGKEKVYGPYPSLAGYGILVVKNRKFEELKPEQVKEIERELKDNKFNDLAGLFVE
HHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHCCHHHHHHHHHHHHCCCHHHHHHHHHH
KLIKEYGVKVNEQLAGI
HHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]