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The map label for this gene is panD

Identifier: 15605956

GI number: 15605956

Start: 322201

End: 322575

Strand: Direct

Name: panD

Synonym: aq_476

Alternate gene names: 15605956

Gene position: 322201-322575 (Clockwise)

Preceding gene: 15605954

Following gene: 15605957

Centisome position: 20.77

GC content: 47.73

Gene sequence:

>375_bases
ATGCTGAGGGAAATGCTCAAGTCCAAAATACACAGGTTAACGGTAACGGATGCGGATCTTCATTACGAGGGAAGTCTGTC
CTTAGACGAGTATTTAATGGAGCTTGCGGACTTAAAGCCCTTCGAAAAGATAGACGTTTACAACATTAACAACGGTGCGA
GGTTTCAGACTTACGTTATCCCCGCCCCGAGGTATTCGGGAGAGGTTAAGTTAAACGGTGCGGCCGCAAGACTCGGGCAC
AAAGGCGACCTTATAATAATCGCCTCTTACGCCCAGTACACGGAGGAGGAGCTAGAGAACTACGCTCCCAAGCTCATTTT
CGTTAACGAGAAGAACCAGCCTGTTGAAGTAAAAGAAAGTACGGAGGTGAAGTGA

Upstream 100 bases:

>100_bases
TTTCCCCCACGCTTTCATAGAAAAGATTATACACTTATGATTTAAACAGCTTGCCTTATATTTTTATTAGCATATTCTTA
ATTAATCTTGGAGGAGCCGA

Downstream 100 bases:

>100_bases
GATGTTTATGAACGTTCCGGAAGTTACACCAGAAGAAGCTAAGAAGATGCTTGAGGAAGAAAAGGATAAAGTTGTACTTT
TAGACGTTAGAACTCCGCCC

Product: aspartate alpha-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MLREMLKSKIHRLTVTDADLHYEGSLSLDEYLMELADLKPFEKIDVYNINNGARFQTYVIPAPRYSGEVKLNGAAARLGH
KGDLIIIASYAQYTEEELENYAPKLIFVNEKNQPVEVKESTEVK

Sequences:

>Translated_124_residues
MLREMLKSKIHRLTVTDADLHYEGSLSLDEYLMELADLKPFEKIDVYNINNGARFQTYVIPAPRYSGEVKLNGAAARLGH
KGDLIIIASYAQYTEEELENYAPKLIFVNEKNQPVEVKESTEVK
>Mature_124_residues
MLREMLKSKIHRLTVTDADLHYEGSLSLDEYLMELADLKPFEKIDVYNINNGARFQTYVIPAPRYSGEVKLNGAAARLGH
KGDLIIIASYAQYTEEELENYAPKLIFVNEKNQPVEVKESTEVK

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=113, Percent_Identity=42.4778761061947, Blast_Score=108, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND_AQUAE (O66773)

Other databases:

- EMBL:   AE000657
- PIR:   A70343
- RefSeq:   NP_213333.1
- ProteinModelPortal:   O66773
- SMR:   O66773
- GeneID:   1193191
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_476
- NMPDR:   fig|224324.1.peg.348
- HOGENOM:   HBG302821
- OMA:   LYSKIHR
- PhylomeDB:   O66773
- ProtClustDB:   PRK05449
- BioCyc:   AAEO224324:AQ_476-MONOMER
- BRENDA:   4.1.1.11
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294
- TIGRFAMs:   TIGR00223

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 14163; Mature: 14163

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: ACT_SITE 25-25 ACT_SITE 58-58 BINDING 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLREMLKSKIHRLTVTDADLHYEGSLSLDEYLMELADLKPFEKIDVYNINNGARFQTYVI
CHHHHHHHHHHEEEEECCCEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEE
PAPRYSGEVKLNGAAARLGHKGDLIIIASYAQYTEEELENYAPKLIFVNEKNQPVEVKES
ECCCCCCEEEECCHHEECCCCCCEEEEECCHHHHHHHHHHCCCEEEEECCCCCCEEECCC
TEVK
CCCC
>Mature Secondary Structure
MLREMLKSKIHRLTVTDADLHYEGSLSLDEYLMELADLKPFEKIDVYNINNGARFQTYVI
CHHHHHHHHHHEEEEECCCEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEE
PAPRYSGEVKLNGAAARLGHKGDLIIIASYAQYTEEELENYAPKLIFVNEKNQPVEVKES
ECCCCCCEEEECCHHEECCCCCCEEEEECCHHHHHHHHHHCCCEEEEECCCCCCEEECCC
TEVK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320