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The map label for this gene is czcB3 [H]

Identifier: 15605952

GI number: 15605952

Start: 315416

End: 316495

Strand: Direct

Name: czcB3 [H]

Synonym: aq_468

Alternate gene names: 15605952

Gene position: 315416-316495 (Clockwise)

Preceding gene: 15605951

Following gene: 15605953

Centisome position: 20.33

GC content: 45.37

Gene sequence:

>1080_bases
ATGAAAAAAATTCTCATTTATTTAATAACTCTTTTAGCCTTTTCCTTTGGAGGTGAAGAGCATGGGCATGAAGAGGAAAT
ACACCTTACAGATAAACAGATAAAACTGCTCGGGATAAAACTCTACGAAGTTAAAAGAGAACCTGTGGGAAAGATTGTAA
AGATGCCCGCTGAAGTAGAAGAAAATCCCCTTCTCAATTACGTGGTTTACAGTCCCGTTGAGGGAATTGTGAGGAAGCTC
TACAAGAAAGAGGGGGACCTCGTGAAAAAGGGAGAACCGCTTGCGGAAGTATACTCACCCGAGCTTGCGAACCTCATCGG
GGAAGTTCGCACCGCAAAGGTAAGGATGGAAAGTGCGAGAAAGCTCTACGAGAGGTATAAAAAACTTTACGAACAAAAGG
TCATAAAGTACACGCTCTTTTACAACGCCATGGTGGAGTATGAGAGGGCTAAGGGTGAGTATGAGGCACTCCTTTCTAAA
CTCAAGAGTTTTGGAGAAGTAAAGGGCTACAACTTAGTCCTTCGCTCTCCCGGTAAGGGTTACGTTGTAAAGCAGAACGT
CGTCCTCGGAGAAAGCGTGGGGCTAGACAACTTCCTCTTTAAGATTCACTCCCACGAGGTGGTTTGGGTTTACGGCTGGG
CGGATGAAAAATCCGCAAAAGACATAAAGGAAGGGATGAAAGGCACGGCTCTCTCTCACGAGGATAGACTTCCGTGTCGT
GTGGACTACATCGGTCACGAGGTGGACAGAAAGACGAGAAGGGTAAAGGTAAGGTGTGTAGCTCAAAACAAAAACCATGT
GCTAAAACCGGGGATGTTCGTGGAACTCCTCGTAAAAACACAAGGAGAACCTGCAATACTCATTCCCAAAAATGCAGTTC
AGGAAATTGAAGGAAAGAAAGTAGTGTTCGTCAGAACCGAGGAGGGATTTGAAGCAAGACCAGTAACTATACTTAAAGAG
CTCAACGGCTACTACGTCGTCCTTGAGGGATTAAAGGAAGGAGAGAGAATAGCGGTCACGGGAACGGTATTCCTCAAAAC
TAAGCTCGTAGGAGTTGAAGAAGGAGGACATGCTCACTAA

Upstream 100 bases:

>100_bases
TGAGGAGAAAATATTACGAGCTCTTAATAAACAGGGCTGAATTGCTCTTAGATATCCACAGGACCTACTCTGAGTTCATA
GAAATAGGAGGTTGGAGGAG

Downstream 100 bases:

>100_bases
TCGGAGGTGGCGGTATGTTCAGAGCGGTTTTAAAGTACAGGCTTTTAGTTCTTATAGCCCTTGTAGGCACGGTTATATAC
GGTGTTTACAGTTTTAAAAA

Product: cation efflux system (czcB-like)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKKILIYLITLLAFSFGGEEHGHEEEIHLTDKQIKLLGIKLYEVKREPVGKIVKMPAEVEENPLLNYVVYSPVEGIVRKL
YKKEGDLVKKGEPLAEVYSPELANLIGEVRTAKVRMESARKLYERYKKLYEQKVIKYTLFYNAMVEYERAKGEYEALLSK
LKSFGEVKGYNLVLRSPGKGYVVKQNVVLGESVGLDNFLFKIHSHEVVWVYGWADEKSAKDIKEGMKGTALSHEDRLPCR
VDYIGHEVDRKTRRVKVRCVAQNKNHVLKPGMFVELLVKTQGEPAILIPKNAVQEIEGKKVVFVRTEEGFEARPVTILKE
LNGYYVVLEGLKEGERIAVTGTVFLKTKLVGVEEGGHAH

Sequences:

>Translated_359_residues
MKKILIYLITLLAFSFGGEEHGHEEEIHLTDKQIKLLGIKLYEVKREPVGKIVKMPAEVEENPLLNYVVYSPVEGIVRKL
YKKEGDLVKKGEPLAEVYSPELANLIGEVRTAKVRMESARKLYERYKKLYEQKVIKYTLFYNAMVEYERAKGEYEALLSK
LKSFGEVKGYNLVLRSPGKGYVVKQNVVLGESVGLDNFLFKIHSHEVVWVYGWADEKSAKDIKEGMKGTALSHEDRLPCR
VDYIGHEVDRKTRRVKVRCVAQNKNHVLKPGMFVELLVKTQGEPAILIPKNAVQEIEGKKVVFVRTEEGFEARPVTILKE
LNGYYVVLEGLKEGERIAVTGTVFLKTKLVGVEEGGHAH
>Mature_359_residues
MKKILIYLITLLAFSFGGEEHGHEEEIHLTDKQIKLLGIKLYEVKREPVGKIVKMPAEVEENPLLNYVVYSPVEGIVRKL
YKKEGDLVKKGEPLAEVYSPELANLIGEVRTAKVRMESARKLYERYKKLYEQKVIKYTLFYNAMVEYERAKGEYEALLSK
LKSFGEVKGYNLVLRSPGKGYVVKQNVVLGESVGLDNFLFKIHSHEVVWVYGWADEKSAKDIKEGMKGTALSHEDRLPCR
VDYIGHEVDRKTRRVKVRCVAQNKNHVLKPGMFVELLVKTQGEPAILIPKNAVQEIEGKKVVFVRTEEGFEARPVTILKE
LNGYYVVLEGLKEGERIAVTGTVFLKTKLVGVEEGGHAH

Specific function: Component of the NCC cation efflux system that confers resistance to nickel, cobalt and cadmium [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=360, Percent_Identity=24.1666666666667, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1786668, Length=331, Percent_Identity=22.6586102719033, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40847; Mature: 40847

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILIYLITLLAFSFGGEEHGHEEEIHLTDKQIKLLGIKLYEVKREPVGKIVKMPAEVE
CHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEEEEEEECCCCHHHHHCCCCCCC
ENPLLNYVVYSPVEGIVRKLYKKEGDLVKKGEPLAEVYSPELANLIGEVRTAKVRMESAR
CCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
KLYERYKKLYEQKVIKYTLFYNAMVEYERAKGEYEALLSKLKSFGEVKGYNLVLRSPGKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
YVVKQNVVLGESVGLDNFLFKIHSHEVVWVYGWADEKSAKDIKEGMKGTALSHEDRLPCR
EEEECCEEECCCCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCEE
VDYIGHEVDRKTRRVKVRCVAQNKNHVLKPGMFVELLVKTQGEPAILIPKNAVQEIEGKK
EEHHCCHHHCCCEEEEEEEEECCCCCEECCCCEEEEEEECCCCCEEEECCHHHHHCCCCE
VVFVRTEEGFEARPVTILKELNGYYVVLEGLKEGERIAVTGTVFLKTKLVGVEEGGHAH
EEEEEECCCCCCCCHHHHHHCCCEEEEEECCCCCCEEEEEEEEEEEEEEEEECCCCCCC
>Mature Secondary Structure
MKKILIYLITLLAFSFGGEEHGHEEEIHLTDKQIKLLGIKLYEVKREPVGKIVKMPAEVE
CHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEEEEEEECCCCHHHHHCCCCCCC
ENPLLNYVVYSPVEGIVRKLYKKEGDLVKKGEPLAEVYSPELANLIGEVRTAKVRMESAR
CCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
KLYERYKKLYEQKVIKYTLFYNAMVEYERAKGEYEALLSKLKSFGEVKGYNLVLRSPGKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
YVVKQNVVLGESVGLDNFLFKIHSHEVVWVYGWADEKSAKDIKEGMKGTALSHEDRLPCR
EEEECCEEECCCCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCEE
VDYIGHEVDRKTRRVKVRCVAQNKNHVLKPGMFVELLVKTQGEPAILIPKNAVQEIEGKK
EEHHCCHHHCCCEEEEEEEEECCCCCEECCCCEEEEEEECCCCCEEEECCHHHHHCCCCE
VVFVRTEEGFEARPVTILKELNGYYVVLEGLKEGERIAVTGTVFLKTKLVGVEEGGHAH
EEEEEECCCCCCCCHHHHHHCCCEEEEEECCCCCCEEEEEEEEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961470 [H]