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The map label for this gene is rfaC2 [H]

Identifier: 15605721

GI number: 15605721

Start: 88593

End: 89546

Strand: Direct

Name: rfaC2 [H]

Synonym: aq_145

Alternate gene names: 15605721

Gene position: 88593-89546 (Clockwise)

Preceding gene: 15605720

Following gene: 15605722

Centisome position: 5.71

GC content: 40.46

Gene sequence:

>954_bases
GTGAAAATACTTATCTGGCAGACTGCATACCTCGGGGACGTGGTTCTCGCCACGCCCCTCATACAAACCCTTAAAAAAAA
CTTTCCGGACGCAAAAATAGGCTTTGTGGGAAGACCCTTTATTAAAGAACTTTTTAAAGACGAAGAAGTAGAATTAATTC
CCTATTCAAAAAAGTTCAAAGAAAGCTTTACGGTAATAAGGAAGATAAAAAATTACGACGTAGTGATCTCACCCCACCGT
TCCATGAGAACAGCCCTAATACTCTTTTTTTCAGGAATTAAAGAGAGGATAGGTTTTGACAGGTCAGATCTTCCCTTTTT
GTACACAAAACTCGTGCCCCATCGCTGGGAACTCCACGAAGTAGACAGAAATTTAGAACTTTTAAAACCATTAGGAGTAA
AGGAATTTATTAGAGAGACAAAACTCAAAATGAAAGAAGAAGAGTACAGGAAAATCCTAAATAAATTCAACTTAAAGGAA
AAAAAGTACATTGTTATTTCACCCTTTTCAAACTTCCCGTTAAAGGAGTGGAGCTTAAAAAACTGGAAGGAGTTGGTAAG
GAAACTAAACACTCCCGTCGTAATCACGGGAACGAAAGAGGACGAAGAGAGGAGTAAAGAAATAGATGGAAAGAATGTAG
TAAACCTCGTGGGGAAGACTTCTCTCAGGGAGTTTATGGGAGTTTTGAAAGGAGCAAAATTCGCGATTTCCAACGATTCC
TCGGCAGTTCACGTGGCAAACGCCTTCAGAGTTCCCGCACTCACGATTTACACGGCAACTTCACCCAAGTACGGTTTTTA
CCCTTTAATAGGTGAATACATACAAAACCCCGCTCCCTGCTCACCCTGTTCTCCCAACCCTAAAAAGTGCAAAACGGGAA
CTAAAGAGTGCCTTTACTTTCCTGAGCCCGATTACGTTCTGGAAAAGGCAATACCTTATATTAAAGACTTATGA

Upstream 100 bases:

>100_bases
ACAAGGAAGGAATAGAGAAGTTCTTCAGCTTTACGGTTGTAAAAGAAGGAGATAAGTGGTACATAGCAAAGATTGAAAAA
TATATACCCCAAGTAGGAAG

Downstream 100 bases:

>100_bases
TTTCAGCGTTTGTTGTTACGGGATTTCTCGGAAGCGGTAAGACGAGTCTGATAATAAACTCCGTAAAGGAGCACCTTAAA
GATAAAAAGGTCGCGATAGT

Product: ADP-heptose:LPS heptosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKILIWQTAYLGDVVLATPLIQTLKKNFPDAKIGFVGRPFIKELFKDEEVELIPYSKKFKESFTVIRKIKNYDVVISPHR
SMRTALILFFSGIKERIGFDRSDLPFLYTKLVPHRWELHEVDRNLELLKPLGVKEFIRETKLKMKEEEYRKILNKFNLKE
KKYIVISPFSNFPLKEWSLKNWKELVRKLNTPVVITGTKEDEERSKEIDGKNVVNLVGKTSLREFMGVLKGAKFAISNDS
SAVHVANAFRVPALTIYTATSPKYGFYPLIGEYIQNPAPCSPCSPNPKKCKTGTKECLYFPEPDYVLEKAIPYIKDL

Sequences:

>Translated_317_residues
MKILIWQTAYLGDVVLATPLIQTLKKNFPDAKIGFVGRPFIKELFKDEEVELIPYSKKFKESFTVIRKIKNYDVVISPHR
SMRTALILFFSGIKERIGFDRSDLPFLYTKLVPHRWELHEVDRNLELLKPLGVKEFIRETKLKMKEEEYRKILNKFNLKE
KKYIVISPFSNFPLKEWSLKNWKELVRKLNTPVVITGTKEDEERSKEIDGKNVVNLVGKTSLREFMGVLKGAKFAISNDS
SAVHVANAFRVPALTIYTATSPKYGFYPLIGEYIQNPAPCSPCSPNPKKCKTGTKECLYFPEPDYVLEKAIPYIKDL
>Mature_317_residues
MKILIWQTAYLGDVVLATPLIQTLKKNFPDAKIGFVGRPFIKELFKDEEVELIPYSKKFKESFTVIRKIKNYDVVISPHR
SMRTALILFFSGIKERIGFDRSDLPFLYTKLVPHRWELHEVDRNLELLKPLGVKEFIRETKLKMKEEEYRKILNKFNLKE
KKYIVISPFSNFPLKEWSLKNWKELVRKLNTPVVITGTKEDEERSKEIDGKNVVNLVGKTSLREFMGVLKGAKFAISNDS
SAVHVANAFRVPALTIYTATSPKYGFYPLIGEYIQNPAPCSPCSPNPKKCKTGTKECLYFPEPDYVLEKAIPYIKDL

Specific function: Catalyzes heptose transfer to the lipopolysaccharide core. It transfers a heptose, called heptose(III), to the heptose(II) of the inner core [H]

COG id: COG0859

COG function: function code M; ADP-heptose:LPS heptosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 9 family [H]

Homologues:

Organism=Escherichia coli, GI1790062, Length=285, Percent_Identity=28.0701754385965, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790050, Length=297, Percent_Identity=26.5993265993266, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790051, Length=310, Percent_Identity=25.1612903225806, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002201
- InterPro:   IPR011916 [H]

Pfam domain/function: PF01075 Glyco_transf_9 [H]

EC number: 2.-.-.- [C]

Molecular weight: Translated: 36675; Mature: 36675

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIWQTAYLGDVVLATPLIQTLKKNFPDAKIGFVGRPFIKELFKDEEVELIPYSKKFK
CEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEECCHHHHH
ESFTVIRKIKNYDVVISPHRSMRTALILFFSGIKERIGFDRSDLPFLYTKLVPHRWELHE
HHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHH
VDRNLELLKPLGVKEFIRETKLKMKEEEYRKILNKFNLKEKKYIVISPFSNFPLKEWSLK
HHCCHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHH
NWKELVRKLNTPVVITGTKEDEERSKEIDGKNVVNLVGKTSLREFMGVLKGAKFAISNDS
HHHHHHHHCCCCEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
SAVHVANAFRVPALTIYTATSPKYGFYPLIGEYIQNPAPCSPCSPNPKKCKTGTKECLYF
CEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHEEEC
PEPDYVLEKAIPYIKDL
CCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKILIWQTAYLGDVVLATPLIQTLKKNFPDAKIGFVGRPFIKELFKDEEVELIPYSKKFK
CEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEECCHHHHH
ESFTVIRKIKNYDVVISPHRSMRTALILFFSGIKERIGFDRSDLPFLYTKLVPHRWELHE
HHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHH
VDRNLELLKPLGVKEFIRETKLKMKEEEYRKILNKFNLKEKKYIVISPFSNFPLKEWSLK
HHCCHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHH
NWKELVRKLNTPVVITGTKEDEERSKEIDGKNVVNLVGKTSLREFMGVLKGAKFAISNDS
HHHHHHHHCCCCEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
SAVHVANAFRVPALTIYTATSPKYGFYPLIGEYIQNPAPCSPCSPNPKKCKTGTKECLYF
CEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHEEEC
PEPDYVLEKAIPYIKDL
CCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Glycosyltransferases; Transferring other glycosyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1732225; 1447141; 8041620; 9278503 [H]