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The map label for this gene is nueM [H]

Identifier: 15605715

GI number: 15605715

Start: 83384

End: 84331

Strand: Direct

Name: nueM [H]

Synonym: aq_135

Alternate gene names: 15605715

Gene position: 83384-84331 (Clockwise)

Preceding gene: 15605714

Following gene: 15605716

Centisome position: 5.37

GC content: 42.41

Gene sequence:

>948_bases
ATGAAAGTATTCATAACCGGAGCGACTGGATTTGTTGGGAGGCACATCGTAAGGGAACTATTAAACAGAGGGTATGAGGT
CCACGCTGGTGTAAGGAACTTAAGCAAACTCGAAAGACTCTTCGGAAATCAGGTAAAGGGCTACATAGTGAACTTTGACG
AAAAGGACTCTATAAGGGAAGCATTAGGAAAAGTAAATCCCGACTTCGTAATTCACCTAATAGGCATACTCTATGAAGAA
AAGAAAAAAGGAATAACTTTTGAAAGGGTTCACTACGGCCACACGAAAAACCTTGTAGAAGTTTCAAAGGGGTTCAACGT
AAAGAAGTTCCTATTCATGAGCGCCCTCGGAACCCACGACGAAGCACCCTCCCGTTACCACCAGACCAAAAGGTGGGCGG
AAAGGGAAGTCATAAACTCCGGTCTCAATTACACGATTTTCAGACCTTCTATAATCCTGGGGCCTGAACAAAAACTCTTT
TTTGATATGTACAAAATAACCAAATACATTCCCGTAGTAGCCCTTCCCGATTTCGGGAATTACCAGTTCCAGCCCGTTGA
CGTGAGAGACGTGGCGTGTGCTTACGCGGAAGCCCTTAAAAATCCCGAAACCGACAGGAAGATTTACGAGCTTTGTGGGA
CTAAGGTTGTAACCTTTAAAGAACTCCTTGCGGACATATTCTCCTACTGGGACAGAAAGGTTCTCATGATACCGATGCCC
AAAAAGCTTATGTACTTCGCGGGCTTGATTGTGGAAAAGATAATAGAACCCCCTCCCTTTTCTTCTGACCAGATAAAGAT
GATGTGGAAACCTAACGTGTGCGGAGTGTTAAAAGATGAGGCTATTTCCAACGGAATTAAATCTATTTGCAAAAGAGAAC
CCATACCTTATGAAGAGAGTTTAAAGTGGTCTCTCGAAAATTTTGATATAATAATTAAAGGAAAATAA

Upstream 100 bases:

>100_bases
ATGTGGTAGGTTATAAAACGCACAAAGTGGAAGGTGTTGAACAAGTAGAGAGTTTAGAAGAAATGCTTAAAAAAGTCGAT
GAATTCTTCGGAGGGAGGCT

Downstream 100 bases:

>100_bases
TTTTCAATTAGGAGGTGGAAACATGAGAAAAGGTTTACTCCTAATGGCGGTATTCGCAGGCTTTGTGGTGGCAAAGGAAA
AGATTGACGACAAGGAACTC

Product: NADH dehydrogenase (ubiquinone)

Products: NAD+; ubiquinol

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKVFITGATGFVGRHIVRELLNRGYEVHAGVRNLSKLERLFGNQVKGYIVNFDEKDSIREALGKVNPDFVIHLIGILYEE
KKKGITFERVHYGHTKNLVEVSKGFNVKKFLFMSALGTHDEAPSRYHQTKRWAEREVINSGLNYTIFRPSIILGPEQKLF
FDMYKITKYIPVVALPDFGNYQFQPVDVRDVACAYAEALKNPETDRKIYELCGTKVVTFKELLADIFSYWDRKVLMIPMP
KKLMYFAGLIVEKIIEPPPFSSDQIKMMWKPNVCGVLKDEAISNGIKSICKREPIPYEESLKWSLENFDIIIKGK

Sequences:

>Translated_315_residues
MKVFITGATGFVGRHIVRELLNRGYEVHAGVRNLSKLERLFGNQVKGYIVNFDEKDSIREALGKVNPDFVIHLIGILYEE
KKKGITFERVHYGHTKNLVEVSKGFNVKKFLFMSALGTHDEAPSRYHQTKRWAEREVINSGLNYTIFRPSIILGPEQKLF
FDMYKITKYIPVVALPDFGNYQFQPVDVRDVACAYAEALKNPETDRKIYELCGTKVVTFKELLADIFSYWDRKVLMIPMP
KKLMYFAGLIVEKIIEPPPFSSDQIKMMWKPNVCGVLKDEAISNGIKSICKREPIPYEESLKWSLENFDIIIKGK
>Mature_315_residues
MKVFITGATGFVGRHIVRELLNRGYEVHAGVRNLSKLERLFGNQVKGYIVNFDEKDSIREALGKVNPDFVIHLIGILYEE
KKKGITFERVHYGHTKNLVEVSKGFNVKKFLFMSALGTHDEAPSRYHQTKRWAEREVINSGLNYTIFRPSIILGPEQKLF
FDMYKITKYIPVVALPDFGNYQFQPVDVRDVACAYAEALKNPETDRKIYELCGTKVVTFKELLADIFSYWDRKVLMIPMP
KKLMYFAGLIVEKIIEPPPFSSDQIKMMWKPNVCGVLKDEAISNGIKSICKREPIPYEESLKWSLENFDIIIKGK

Specific function: Unknown

COG id: COG0702

COG function: function code MG; Predicted nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6681764, Length=235, Percent_Identity=29.3617021276596, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI87081793, Length=306, Percent_Identity=18.9542483660131, Blast_Score=81, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24667554, Length=244, Percent_Identity=29.0983606557377, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021295
- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF11066 DUF2867; PF01370 Epimerase [H]

EC number: 1.6.5.3

Molecular weight: Translated: 36341; Mature: 36341

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVFITGATGFVGRHIVRELLNRGYEVHAGVRNLSKLERLFGNQVKGYIVNFDEKDSIRE
CEEEEECCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
ALGKVNPDFVIHLIGILYEEKKKGITFERVHYGHTKNLVEVSKGFNVKKFLFMSALGTHD
HHCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHCCCCHHHHHHHHHHCCCC
EAPSRYHQTKRWAEREVINSGLNYTIFRPSIILGPEQKLFFDMYKITKYIPVVALPDFGN
CCHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCHHHHHHHHHHHHHCCEEECCCCCC
YQFQPVDVRDVACAYAEALKNPETDRKIYELCGTKVVTFKELLADIFSYWDRKVLMIPMP
CEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEECCC
KKLMYFAGLIVEKIIEPPPFSSDQIKMMWKPNVCGVLKDEAISNGIKSICKREPIPYEES
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
LKWSLENFDIIIKGK
CEEECCCEEEEEECC
>Mature Secondary Structure
MKVFITGATGFVGRHIVRELLNRGYEVHAGVRNLSKLERLFGNQVKGYIVNFDEKDSIRE
CEEEEECCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
ALGKVNPDFVIHLIGILYEEKKKGITFERVHYGHTKNLVEVSKGFNVKKFLFMSALGTHD
HHCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHCCCCHHHHHHHHHHCCCC
EAPSRYHQTKRWAEREVINSGLNYTIFRPSIILGPEQKLFFDMYKITKYIPVVALPDFGN
CCHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCHHHHHHHHHHHHHCCEEECCCCCC
YQFQPVDVRDVACAYAEALKNPETDRKIYELCGTKVVTFKELLADIFSYWDRKVLMIPMP
CEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEECCC
KKLMYFAGLIVEKIIEPPPFSSDQIKMMWKPNVCGVLKDEAISNGIKSICKREPIPYEES
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
LKWSLENFDIIIKGK
CEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]