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The map label for this gene is srlE [H]

Identifier: 15603835

GI number: 15603835

Start: 2206919

End: 2207908

Strand: Reverse

Name: srlE [H]

Synonym: PM1970

Alternate gene names: 15603835

Gene position: 2207908-2206919 (Counterclockwise)

Preceding gene: 15603836

Following gene: 15603834

Centisome position: 97.8

GC content: 42.53

Gene sequence:

>990_bases
ATGAATAAAGCAATTTATATTGAAAAAGGAAACGGTGGTTGGGGAGGCCCTTTAACTTTGCCATTAGTTGAAGGAAAAAA
GATCCTGTATATGACAGGCGGTACTCGTCCTGCTATTGTTGATAGATTAATTGAGCTGACTGGTTGGGAAGCCGTAGATG
GTTTTAAAGAGGGTGAACCTGCAACAGAAGAAATTGGTATTGCGATTGTTGATTGTGGTGGCACACTACGTTGCGGTCTT
TATCCCAAACGCCGTATTCCAACAATTAACGTACATGCAACAGGGAAATCTGGTCCACTCGCCGCATATATTGTGGAAGA
TATTTATGTATCAGCGGTTAAACCACAACATATACAGTTAATTGATGCCGATCTGAGCGTAACAGAAAGCGTGACAGAAA
CCCCTACGCCAGCTCAACAATATAAAGAATATGATGCTAATAAAAAAATTACTGAACAAAGTGATGGCTTACTCGCGAGA
ATTGGTATTGGCATGGGCGCTATTGTTGCTGTTTTTTTCCAAGCTGGACGAGATACTATCGATACTGTCTTAAAAACAAT
TCTGCCATTCATGGCATTCGTTTCCGCCTTAATTGGTATTATCATTGCTTCAGGTTTAGGTGATGTAATTGCACATGGCT
TAACGCCTTTAGCAAATAGCCCTATAGGTCTCATCACGCTTGCCTTGATCTGTTCTTTCCCGCTCCTCTCGCCATTCTTA
GGACCTGGTGCAGTAATCGCCCAAGTGATTGGTGTTTTAGTCGGAACACAGATAGGTTTAGGCAATATTCCACCACACTT
AGCACTACCCGCATTATTCGCTATCAACGCTCAGGCAGCTTGTGATTTCATCCCTGTAGGTTTATCTATGGCAGAAGCCA
AGCAAGATACTGTACGCGTTGGCGTACCCGCTGTATTAGTTGGACGTTTCTTAACTGGAGCACCAACAGTATTAGTCGCG
TGGTTAGTTTCTGCTTTTATCTATCACTAA

Upstream 100 bases:

>100_bases
CTTTACGACTGCGCTTTTCGAAAAAAGAATGGGCATCAAACTAGATAGAGAAGTCAGAATCGCGAATTAATTACCTTGCG
AAAATAAGGAGCAACAGAGT

Downstream 100 bases:

>100_bases
ACTTAACGTAATGGACGTTGCCTAGACGTCCATTACCCCCATTTAACTTCAATATTAATACAGATAAGGATTGTAGTTAT
GAAAACTCTTTATCAAAGCA

Product: hypothetical protein

Products: NA

Alternate protein names: EII-Gut; PTS system glucitol/sorbitol-specific EIIB component [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNKAIYIEKGNGGWGGPLTLPLVEGKKILYMTGGTRPAIVDRLIELTGWEAVDGFKEGEPATEEIGIAIVDCGGTLRCGL
YPKRRIPTINVHATGKSGPLAAYIVEDIYVSAVKPQHIQLIDADLSVTESVTETPTPAQQYKEYDANKKITEQSDGLLAR
IGIGMGAIVAVFFQAGRDTIDTVLKTILPFMAFVSALIGIIIASGLGDVIAHGLTPLANSPIGLITLALICSFPLLSPFL
GPGAVIAQVIGVLVGTQIGLGNIPPHLALPALFAINAQAACDFIPVGLSMAEAKQDTVRVGVPAVLVGRFLTGAPTVLVA
WLVSAFIYH

Sequences:

>Translated_329_residues
MNKAIYIEKGNGGWGGPLTLPLVEGKKILYMTGGTRPAIVDRLIELTGWEAVDGFKEGEPATEEIGIAIVDCGGTLRCGL
YPKRRIPTINVHATGKSGPLAAYIVEDIYVSAVKPQHIQLIDADLSVTESVTETPTPAQQYKEYDANKKITEQSDGLLAR
IGIGMGAIVAVFFQAGRDTIDTVLKTILPFMAFVSALIGIIIASGLGDVIAHGLTPLANSPIGLITLALICSFPLLSPFL
GPGAVIAQVIGVLVGTQIGLGNIPPHLALPALFAINAQAACDFIPVGLSMAEAKQDTVRVGVPAVLVGRFLTGAPTVLVA
WLVSAFIYH
>Mature_329_residues
MNKAIYIEKGNGGWGGPLTLPLVEGKKILYMTGGTRPAIVDRLIELTGWEAVDGFKEGEPATEEIGIAIVDCGGTLRCGL
YPKRRIPTINVHATGKSGPLAAYIVEDIYVSAVKPQHIQLIDADLSVTESVTETPTPAQQYKEYDANKKITEQSDGLLAR
IGIGMGAIVAVFFQAGRDTIDTVLKTILPFMAFVSALIGIIIASGLGDVIAHGLTPLANSPIGLITLALICSFPLLSPFL
GPGAVIAQVIGVLVGTQIGLGNIPPHLALPALFAINAQAACDFIPVGLSMAEAKQDTVRVGVPAVLVGRFLTGAPTVLVA
WLVSAFIYH

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG3732

COG function: function code G; Phosphotransferase system sorbitol-specific component IIBC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI48994905, Length=326, Percent_Identity=76.6871165644172, Blast_Score=508, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011638
- InterPro:   IPR011618
- InterPro:   IPR004702 [H]

Pfam domain/function: PF07663 EIIBC-GUT_C; PF03612 EIIBC-GUT_N [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 34484; Mature: 34484

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS51102 PTS_EIIB_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAIYIEKGNGGWGGPLTLPLVEGKKILYMTGGTRPAIVDRLIELTGWEAVDGFKEGEP
CCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHHCCCHHHCCCCCCCC
ATEEIGIAIVDCGGTLRCGLYPKRRIPTINVHATGKSGPLAAYIVEDIYVSAVKPQHIQL
CCHHCCEEEEECCCEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEE
IDADLSVTESVTETPTPAQQYKEYDANKKITEQSDGLLARIGIGMGAIVAVFFQAGRDTI
EECCCHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHH
DTVLKTILPFMAFVSALIGIIIASGLGDVIAHGLTPLANSPIGLITLALICSFPLLSPFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC
GPGAVIAQVIGVLVGTQIGLGNIPPHLALPALFAINAQAACDFIPVGLSMAEAKQDTVRV
CCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHCCEEECCCHHHHHCCCCEEE
GVPAVLVGRFLTGAPTVLVAWLVSAFIYH
CCHHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKAIYIEKGNGGWGGPLTLPLVEGKKILYMTGGTRPAIVDRLIELTGWEAVDGFKEGEP
CCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHHCCCHHHCCCCCCCC
ATEEIGIAIVDCGGTLRCGLYPKRRIPTINVHATGKSGPLAAYIVEDIYVSAVKPQHIQL
CCHHCCEEEEECCCEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEE
IDADLSVTESVTETPTPAQQYKEYDANKKITEQSDGLLARIGIGMGAIVAVFFQAGRDTI
EECCCHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHH
DTVLKTILPFMAFVSALIGIIIASGLGDVIAHGLTPLANSPIGLITLALICSFPLLSPFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC
GPGAVIAQVIGVLVGTQIGLGNIPPHLALPALFAINAQAACDFIPVGLSMAEAKQDTVRV
CCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHCCEEECCCHHHHHCCCCEEE
GVPAVLVGRFLTGAPTVLVAWLVSAFIYH
CCHHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3553176; 9205837; 9278503 [H]