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The map label for this gene is rodA [H]

Identifier: 15603790

GI number: 15603790

Start: 2164577

End: 2165692

Strand: Direct

Name: rodA [H]

Synonym: PM1925

Alternate gene names: 15603790

Gene position: 2164577-2165692 (Clockwise)

Preceding gene: 15603789

Following gene: 15603791

Centisome position: 95.88

GC content: 43.01

Gene sequence:

>1116_bases
ATGCATAAAAAGAATATTTGGCTGTCTTTATGGCGCAAATTGCACATTGATTTATGGCTGTTGATCGGATTGATTGTAAT
TTCCGGTTATGGCTTACTGGTCTTATATAGTGCGTCAGGGGGGAATGAAGCGATGTTTCGTAACCGCTTGATCCAAGTTG
CCTTAGGCTTTGCGGTCATGTTGGTGATGGCACAATTCCCGCCGAAGTTTTATCAGCGCATTGCTCCTCTGCTTTTTGGT
GTCGGTATTATTTTATTAATTTTAGTGGATGTGATTGGGACGACGAGTAAAGGGGCACAACGCTGGTTAGATCTGGGGTT
ATTTCGTTTCCAACCCTCAGAAATTGTAAAACTGGCAGTACCTTTGATGGTGGCGGTTTACCTTGGGAAACGACCATTGC
CACCAACGTTGGGTCAGACCTTTATTGCACTGATTTTAATCCTCGTTCCGACATTGTTAGTGGCAATTCAGCCGGATTTA
GGCACATCGATTTTGGTGAGCGCATCGGGGCTATTTGTCGTCTTTCTCGCAGGAATGAGCTGGTGGTTGATTCTGATTGC
GGTTGTCGGGGTGGCTTGCTTTATTCCGATTATGTGGTTCTATTTAATGCACGATTACCAACGAACGCGTGTATTAACAC
TCTTCGATCCAGAAAAAGATCCATTAGGGGCAGGATTTCATATTTTACAGTCAAAAATTGCGATTGGCTCGGGCGGATTA
AGTGGTAAAGGCTGGATGGAAGGAACACAGTCGCAGTTGGAGTTTTTACCTGAACCGCATACGGATTTTATTTTTGCGGT
ATTAAGTGAAGAATATGGCATGATCGGCTTTCTGATTTTAATGGCCATTTATTTATTTATTGTGGGGCGCGGATTGATGA
TCGGAGTGAACGCTCAAACCGCCTTTGGACGAATTTTAGTGGGTGCGATTACGCTGATTTTCTTCATTTACGTGTTTGTG
AATATTGGCATGGTTAGCGGGATCTTGCCTGTAGTTGGTGTGCCTTTACCTTTAGTCAGTTATGGTGGCACATCTTTTGT
TACCTTAATGGCAGGATTTGGGCTGATTATGTCCATTCATACCCATAAAGAACATTTTTTAAAGGGAACTAATTAA

Upstream 100 bases:

>100_bases
CTGTGGTGCGTCAAATTATGGATTATTATTTAACGCAACGATTGCCTCAAATATCGCGTTTATCTCCTGCTGACTCGTTA
GCAACTGAGGACTCAGAATA

Downstream 100 bases:

>100_bases
ACGATTTATTATCTTAGATAGTGATTCTTAATAATTGAACTGAACGATGATGAAACAAAAAATTTTTCAAATATTGACCG
CACTTTGTTGCATATTCTAT

Product: RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MHKKNIWLSLWRKLHIDLWLLIGLIVISGYGLLVLYSASGGNEAMFRNRLIQVALGFAVMLVMAQFPPKFYQRIAPLLFG
VGIILLILVDVIGTTSKGAQRWLDLGLFRFQPSEIVKLAVPLMVAVYLGKRPLPPTLGQTFIALILILVPTLLVAIQPDL
GTSILVSASGLFVVFLAGMSWWLILIAVVGVACFIPIMWFYLMHDYQRTRVLTLFDPEKDPLGAGFHILQSKIAIGSGGL
SGKGWMEGTQSQLEFLPEPHTDFIFAVLSEEYGMIGFLILMAIYLFIVGRGLMIGVNAQTAFGRILVGAITLIFFIYVFV
NIGMVSGILPVVGVPLPLVSYGGTSFVTLMAGFGLIMSIHTHKEHFLKGTN

Sequences:

>Translated_371_residues
MHKKNIWLSLWRKLHIDLWLLIGLIVISGYGLLVLYSASGGNEAMFRNRLIQVALGFAVMLVMAQFPPKFYQRIAPLLFG
VGIILLILVDVIGTTSKGAQRWLDLGLFRFQPSEIVKLAVPLMVAVYLGKRPLPPTLGQTFIALILILVPTLLVAIQPDL
GTSILVSASGLFVVFLAGMSWWLILIAVVGVACFIPIMWFYLMHDYQRTRVLTLFDPEKDPLGAGFHILQSKIAIGSGGL
SGKGWMEGTQSQLEFLPEPHTDFIFAVLSEEYGMIGFLILMAIYLFIVGRGLMIGVNAQTAFGRILVGAITLIFFIYVFV
NIGMVSGILPVVGVPLPLVSYGGTSFVTLMAGFGLIMSIHTHKEHFLKGTN
>Mature_371_residues
MHKKNIWLSLWRKLHIDLWLLIGLIVISGYGLLVLYSASGGNEAMFRNRLIQVALGFAVMLVMAQFPPKFYQRIAPLLFG
VGIILLILVDVIGTTSKGAQRWLDLGLFRFQPSEIVKLAVPLMVAVYLGKRPLPPTLGQTFIALILILVPTLLVAIQPDL
GTSILVSASGLFVVFLAGMSWWLILIAVVGVACFIPIMWFYLMHDYQRTRVLTLFDPEKDPLGAGFHILQSKIAIGSGGL
SGKGWMEGTQSQLEFLPEPHTDFIFAVLSEEYGMIGFLILMAIYLFIVGRGLMIGVNAQTAFGRILVGAITLIFFIYVFV
NIGMVSGILPVVGVPLPLVSYGGTSFVTLMAGFGLIMSIHTHKEHFLKGTN

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=360, Percent_Identity=63.3333333333333, Blast_Score=438, Evalue=1e-124,
Organism=Escherichia coli, GI1786277, Length=372, Percent_Identity=33.3333333333333, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40768; Mature: 40768

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKKNIWLSLWRKLHIDLWLLIGLIVISGYGLLVLYSASGGNEAMFRNRLIQVALGFAVM
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
LVMAQFPPKFYQRIAPLLFGVGIILLILVDVIGTTSKGAQRWLDLGLFRFQPSEIVKLAV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHH
PLMVAVYLGKRPLPPTLGQTFIALILILVPTLLVAIQPDLGTSILVSASGLFVVFLAGMS
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHH
WWLILIAVVGVACFIPIMWFYLMHDYQRTRVLTLFDPEKDPLGAGFHILQSKIAIGSGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCC
SGKGWMEGTQSQLEFLPEPHTDFIFAVLSEEYGMIGFLILMAIYLFIVGRGLMIGVNAQT
CCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCHH
AFGRILVGAITLIFFIYVFVNIGMVSGILPVVGVPLPLVSYGGTSFVTLMAGFGLIMSIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHH
THKEHFLKGTN
HHHHHHCCCCC
>Mature Secondary Structure
MHKKNIWLSLWRKLHIDLWLLIGLIVISGYGLLVLYSASGGNEAMFRNRLIQVALGFAVM
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
LVMAQFPPKFYQRIAPLLFGVGIILLILVDVIGTTSKGAQRWLDLGLFRFQPSEIVKLAV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHH
PLMVAVYLGKRPLPPTLGQTFIALILILVPTLLVAIQPDLGTSILVSASGLFVVFLAGMS
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHH
WWLILIAVVGVACFIPIMWFYLMHDYQRTRVLTLFDPEKDPLGAGFHILQSKIAIGSGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCC
SGKGWMEGTQSQLEFLPEPHTDFIFAVLSEEYGMIGFLILMAIYLFIVGRGLMIGVNAQT
CCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCHH
AFGRILVGAITLIFFIYVFVNIGMVSGILPVVGVPLPLVSYGGTSFVTLMAGFGLIMSIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHH
THKEHFLKGTN
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]