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The map label for this gene is cyaA

Identifier: 15603676

GI number: 15603676

Start: 2039271

End: 2041787

Strand: Reverse

Name: cyaA

Synonym: PM1811

Alternate gene names: 15603676

Gene position: 2041787-2039271 (Counterclockwise)

Preceding gene: 161723305

Following gene: 15603675

Centisome position: 90.45

GC content: 39.53

Gene sequence:

>2517_bases
TTGAATTACGATCTCTTTAGTGCCCAAAAGAAAGTGGAGTATTTAGATAAGCTACGTATTGAGCGCGCATTATCTGGTTC
TTCTGGCGAATTTCAGCACGTTTTTCAGTTACTTACGTTGTTGTTACATATTAACCACCCTAATCTGCCCGGCTACGTTG
CTGACGCGCCTGTAGGGATTGCTGACTTTGTTATTTCCCCCTACCAAAAACAATATCTGCTCACAACCGTGCCGAGCTTA
GAGGCTAATCAGTCACTGCTCCCGTCCTTTTCTTACCGTAGTACCAATGCCATTTTAGGTGTCTATGTGATGGGCAGTAT
TGCCTCTATTTCACAAACACCAAAATCGGATCTAGATACTTGGGTCTGCCATCGTGATGATTTAAGTACAAAAGAAAAAG
AAGCCTTACAACGTAAAACACATTTATTAAAAAATTGGGCGAAACAATTCAACATTGAAATCAATTTTTATTTAATGGAT
CAAAAGCGGTTCCGTTGTTTCCGTTATGCGGAACCGTTAACAGCAGAAAACTGCGGTTCAGCTCAGTATATGTTATTGCT
AGACGAATTCTATCGCTCTGCGATTCGCTTAGCAGGCAAACCATTACTCTGGCTACATTTATTGATCGAACAAGAAGAAA
ATTATGAAAGTGAAGTCGAGCGGTTAGTCCGTACCCAACAAATTTGTCTTGATGATTGGGTTGATTTTGGTGGTTTGGGG
CAACTTTCCGCCAACGAGTATTTTGGTGCAAGTTTATGGCAACTGTACAAAGGGATCGATGCGCCTTATAAATCGGTCAT
CAAAATCTTATTGTTAGAAACGTATTCATCGGAATACCCCAATACCTATTTAATTGCGCGCCAATTTAAAGAAGAATTAT
TAACAGGTAAGCTCAACCCAAGCCATCATTTTGATCCCTATTTAGCCATGTTGCAACGTGCGACACGCTACCTCACGAAA
CACAATGAATTAAAACGTTTAGGTTTTGTTCGCCGCAGTGTTTACTTAAAAGCAACTGAAGGTATGTGTTGGCAAGATCC
TAATGCGACAAATAATTGGCGCTTACAGCATTTGCAAAAGCTCATCCAAGAATGGGATTGGTCGGATGCCTTAATTGAAG
AATTAAATCAACGCGCTAACTGGAAAATCAAACAAGTCAAAAAAGCACATAACAGCTTAATTAAATTCTTAATGCTCAGT
TATCGTAATTTAGTGGCCTTTGCTCGTAAACACAAAGTGAACTCGAGTATCATGCCACAAGACATCAGTGTGCTTACACG
CAAACTGTATACAGCATTTGAAGAATTACCCGGTAAAATTACCCTACTTAACCCACAAATTTCACTCAATTTATCTGAGA
AGAATTTACTGTTTTTTGAAGTCAAAGGCAGTAAAACGTTCAAAGACGGGTGGTATGTGGTGAATCAAACACCAAGTGTT
GCCGGCTTTGTACAAAAACGCTATACCGAATACAGTGAGAGTTTAAACAAACTGGTCGCTTGGGCGTATTTTAATCGTAT
TCTCACCGCCAATACCGACTTACACATTATTAGTCCCAATGTTTCCTTAACAACCTTGCGGCATTTTGTCACCGATTTAC
GTCTCTCATTTCCGGTCACGGTTTCCTCTGTCACGAATGAGGATTTAACTCATGCTTGTGAAATTCGGAGCTTAATTGTG
GCAGTTAACTTAACCGTTGACCCAACCAAAAAAATCACACAAGTCAAATCTCGCATTCAAGCCAGTGATTTATTTAGTTT
TGGACCGAAAGAAGAAAGTTTAGTCGGTAGTATCGATATTACTTACCGTAATCTTTGGAATGAAATTAGAACCTTACATT
TTGAAGGACCGAATGCGATCCTCTTAGCCTTGAAGGTGCTGTCAAATAAAATTCATCGTGGTGCCCCTTCACCAAAATTG
ATTCAAGTGTTTTCTTATAGTCATCGTTACCGCCGGACGTTGAGTAATATTGTCACCGCTTTGATCAACCGCTGTATTAG
TATCCAAATTGGCGACGCACTTCCACCACAAAATAATCTATTGCGTGTGGCGGGTAAAAACTGGCAGTTTTTCTTTGAAG
AGCGTGGCATCAGCTTACAAGAAATTCACTCAAATGAAGAATTAGAAGCCACTGGCTTTGATACCGCGCTACAAACCGAA
GTGGAAGAAAAAGAAAGCGCCTTACCCGATACCTCACGAACTTACCCCCCAGAGATTGATCACTTTGCCAGTGAGGGCTT
TTTACAATTTTTCTTTGAAGATAATTCTGATGGTTCTTTTAATGTCTATATTTTAGATGAAGCCAATCGCATCGAAATTT
ACCGTAACTGCGATGGACAAAAAGAAAAGAAGATTTTGGAGATTAACCACATTTATCAATCTTCAGGCTTGGATGAAAAT
AACAATCCGTATAAAATTGTGCAGCGTGATTTTAACTATCCGCAATTCTATCAATTATTATTACAAGAGAATGGCGTAAA
AATCGTACCATTCCACAGTCGATTAGCGATGTCATAA

Upstream 100 bases:

>100_bases
TAAATGTCAGTTTCCATTTAAATTTTTTGCTTTCAGTTATACCAAGTGTTAGAGTACTTAGGTGGAGCGAATCTCGTCAT
ATCTGTGAGTGGAATATCAT

Downstream 100 bases:

>100_bases
CATATTGGGGGTTATATGTCAGAAAAAATGAAAGTGTTGATTATCGACGATCATCCATTGATGCGTCGAGGAATCAAACA
ACTTATGGAATTAGCGCCAA

Product: adenylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase; Adenylyl cyclase

Number of amino acids: Translated: 838; Mature: 838

Protein sequence:

>838_residues
MNYDLFSAQKKVEYLDKLRIERALSGSSGEFQHVFQLLTLLLHINHPNLPGYVADAPVGIADFVISPYQKQYLLTTVPSL
EANQSLLPSFSYRSTNAILGVYVMGSIASISQTPKSDLDTWVCHRDDLSTKEKEALQRKTHLLKNWAKQFNIEINFYLMD
QKRFRCFRYAEPLTAENCGSAQYMLLLDEFYRSAIRLAGKPLLWLHLLIEQEENYESEVERLVRTQQICLDDWVDFGGLG
QLSANEYFGASLWQLYKGIDAPYKSVIKILLLETYSSEYPNTYLIARQFKEELLTGKLNPSHHFDPYLAMLQRATRYLTK
HNELKRLGFVRRSVYLKATEGMCWQDPNATNNWRLQHLQKLIQEWDWSDALIEELNQRANWKIKQVKKAHNSLIKFLMLS
YRNLVAFARKHKVNSSIMPQDISVLTRKLYTAFEELPGKITLLNPQISLNLSEKNLLFFEVKGSKTFKDGWYVVNQTPSV
AGFVQKRYTEYSESLNKLVAWAYFNRILTANTDLHIISPNVSLTTLRHFVTDLRLSFPVTVSSVTNEDLTHACEIRSLIV
AVNLTVDPTKKITQVKSRIQASDLFSFGPKEESLVGSIDITYRNLWNEIRTLHFEGPNAILLALKVLSNKIHRGAPSPKL
IQVFSYSHRYRRTLSNIVTALINRCISIQIGDALPPQNNLLRVAGKNWQFFFEERGISLQEIHSNEELEATGFDTALQTE
VEEKESALPDTSRTYPPEIDHFASEGFLQFFFEDNSDGSFNVYILDEANRIEIYRNCDGQKEKKILEINHIYQSSGLDEN
NNPYKIVQRDFNYPQFYQLLLQENGVKIVPFHSRLAMS

Sequences:

>Translated_838_residues
MNYDLFSAQKKVEYLDKLRIERALSGSSGEFQHVFQLLTLLLHINHPNLPGYVADAPVGIADFVISPYQKQYLLTTVPSL
EANQSLLPSFSYRSTNAILGVYVMGSIASISQTPKSDLDTWVCHRDDLSTKEKEALQRKTHLLKNWAKQFNIEINFYLMD
QKRFRCFRYAEPLTAENCGSAQYMLLLDEFYRSAIRLAGKPLLWLHLLIEQEENYESEVERLVRTQQICLDDWVDFGGLG
QLSANEYFGASLWQLYKGIDAPYKSVIKILLLETYSSEYPNTYLIARQFKEELLTGKLNPSHHFDPYLAMLQRATRYLTK
HNELKRLGFVRRSVYLKATEGMCWQDPNATNNWRLQHLQKLIQEWDWSDALIEELNQRANWKIKQVKKAHNSLIKFLMLS
YRNLVAFARKHKVNSSIMPQDISVLTRKLYTAFEELPGKITLLNPQISLNLSEKNLLFFEVKGSKTFKDGWYVVNQTPSV
AGFVQKRYTEYSESLNKLVAWAYFNRILTANTDLHIISPNVSLTTLRHFVTDLRLSFPVTVSSVTNEDLTHACEIRSLIV
AVNLTVDPTKKITQVKSRIQASDLFSFGPKEESLVGSIDITYRNLWNEIRTLHFEGPNAILLALKVLSNKIHRGAPSPKL
IQVFSYSHRYRRTLSNIVTALINRCISIQIGDALPPQNNLLRVAGKNWQFFFEERGISLQEIHSNEELEATGFDTALQTE
VEEKESALPDTSRTYPPEIDHFASEGFLQFFFEDNSDGSFNVYILDEANRIEIYRNCDGQKEKKILEINHIYQSSGLDEN
NNPYKIVQRDFNYPQFYQLLLQENGVKIVPFHSRLAMS
>Mature_838_residues
MNYDLFSAQKKVEYLDKLRIERALSGSSGEFQHVFQLLTLLLHINHPNLPGYVADAPVGIADFVISPYQKQYLLTTVPSL
EANQSLLPSFSYRSTNAILGVYVMGSIASISQTPKSDLDTWVCHRDDLSTKEKEALQRKTHLLKNWAKQFNIEINFYLMD
QKRFRCFRYAEPLTAENCGSAQYMLLLDEFYRSAIRLAGKPLLWLHLLIEQEENYESEVERLVRTQQICLDDWVDFGGLG
QLSANEYFGASLWQLYKGIDAPYKSVIKILLLETYSSEYPNTYLIARQFKEELLTGKLNPSHHFDPYLAMLQRATRYLTK
HNELKRLGFVRRSVYLKATEGMCWQDPNATNNWRLQHLQKLIQEWDWSDALIEELNQRANWKIKQVKKAHNSLIKFLMLS
YRNLVAFARKHKVNSSIMPQDISVLTRKLYTAFEELPGKITLLNPQISLNLSEKNLLFFEVKGSKTFKDGWYVVNQTPSV
AGFVQKRYTEYSESLNKLVAWAYFNRILTANTDLHIISPNVSLTTLRHFVTDLRLSFPVTVSSVTNEDLTHACEIRSLIV
AVNLTVDPTKKITQVKSRIQASDLFSFGPKEESLVGSIDITYRNLWNEIRTLHFEGPNAILLALKVLSNKIHRGAPSPKL
IQVFSYSHRYRRTLSNIVTALINRCISIQIGDALPPQNNLLRVAGKNWQFFFEERGISLQEIHSNEELEATGFDTALQTE
VEEKESALPDTSRTYPPEIDHFASEGFLQFFFEDNSDGSFNVYILDEANRIEIYRNCDGQKEKKILEINHIYQSSGLDEN
NNPYKIVQRDFNYPQFYQLLLQENGVKIVPFHSRLAMS

Specific function: Unknown

COG id: COG3072

COG function: function code F; Adenylate cyclase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenylyl cyclase class-1 family

Homologues:

Organism=Escherichia coli, GI1790238, Length=836, Percent_Identity=41.9856459330144, Blast_Score=663, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYAA_PASMU (Q05766)

Other databases:

- EMBL:   M68901
- EMBL:   AE004439
- PIR:   A38172
- RefSeq:   NP_246750.1
- GeneID:   1245158
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1811
- NMPDR:   fig|272843.1.peg.1812
- HOGENOM:   HBG678054
- OMA:   LWQLYKG
- ProtClustDB:   PRK09450
- BioCyc:   PMUL272843:PM1811-MONOMER
- BRENDA:   4.6.1.1
- GO:   GO:0005737
- InterPro:   IPR000274
- PIRSF:   PIRSF001444

Pfam domain/function: PF01295 Adenylate_cycl

EC number: =4.6.1.1

Molecular weight: Translated: 96800; Mature: 96800

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS01092 ADENYLATE_CYCLASE_1_1; PS01093 ADENYLATE_CYCLASE_1_2; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYDLFSAQKKVEYLDKLRIERALSGSSGEFQHVFQLLTLLLHINHPNLPGYVADAPVGI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCH
ADFVISPYQKQYLLTTVPSLEANQSLLPSFSYRSTNAILGVYVMGSIASISQTPKSDLDT
HHHHHCCCHHCEEEEECCCCCCCCHHCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCHH
WVCHRDDLSTKEKEALQRKTHLLKNWAKQFNIEINFYLMDQKRFRCFRYAEPLTAENCGS
HEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCHHHHHHHHCCCCCCCCCCC
AQYMLLLDEFYRSAIRLAGKPLLWLHLLIEQEENYESEVERLVRTQQICLDDWVDFGGLG
CHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
QLSANEYFGASLWQLYKGIDAPYKSVIKILLLETYSSEYPNTYLIARQFKEELLTGKLNP
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
SHHFDPYLAMLQRATRYLTKHNELKRLGFVRRSVYLKATEGMCWQDPNATNNWRLQHLQK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHH
LIQEWDWSDALIEELNQRANWKIKQVKKAHNSLIKFLMLSYRNLVAFARKHKVNSSIMPQ
HHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
DISVLTRKLYTAFEELPGKITLLNPQISLNLSEKNLLFFEVKGSKTFKDGWYVVNQTPSV
HHHHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCEEEEEECCCCEECCCEEEEECCCCH
AGFVQKRYTEYSESLNKLVAWAYFNRILTANTDLHIISPNVSLTTLRHFVTDLRLSFPVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCEE
VSSVTNEDLTHACEIRSLIVAVNLTVDPTKKITQVKSRIQASDLFSFGPKEESLVGSIDI
EECCCCHHHHHHHHHEEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEH
TYRNLWNEIRTLHFEGPNAILLALKVLSNKIHRGAPSPKLIQVFSYSHRYRRTLSNIVTA
HHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LINRCISIQIGDALPPQNNLLRVAGKNWQFFFEERGISLQEIHSNEELEATGFDTALQTE
HHHHHEEEEECCCCCCCCCEEEEECCCCEEEEECCCCCHHHHCCCCCCCCCCCCHHHHHH
VEEKESALPDTSRTYPPEIDHFASEGFLQFFFEDNSDGSFNVYILDEANRIEIYRNCDGQ
HHHHHHCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCEEEEEEEECCCEEEEEECCCCH
KEKKILEINHIYQSSGLDENNNPYKIVQRDFNYPQFYQLLLQENGVKIVPFHSRLAMS
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEHHHHCCC
>Mature Secondary Structure
MNYDLFSAQKKVEYLDKLRIERALSGSSGEFQHVFQLLTLLLHINHPNLPGYVADAPVGI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCH
ADFVISPYQKQYLLTTVPSLEANQSLLPSFSYRSTNAILGVYVMGSIASISQTPKSDLDT
HHHHHCCCHHCEEEEECCCCCCCCHHCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCHH
WVCHRDDLSTKEKEALQRKTHLLKNWAKQFNIEINFYLMDQKRFRCFRYAEPLTAENCGS
HEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCHHHHHHHHCCCCCCCCCCC
AQYMLLLDEFYRSAIRLAGKPLLWLHLLIEQEENYESEVERLVRTQQICLDDWVDFGGLG
CHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
QLSANEYFGASLWQLYKGIDAPYKSVIKILLLETYSSEYPNTYLIARQFKEELLTGKLNP
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
SHHFDPYLAMLQRATRYLTKHNELKRLGFVRRSVYLKATEGMCWQDPNATNNWRLQHLQK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHH
LIQEWDWSDALIEELNQRANWKIKQVKKAHNSLIKFLMLSYRNLVAFARKHKVNSSIMPQ
HHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
DISVLTRKLYTAFEELPGKITLLNPQISLNLSEKNLLFFEVKGSKTFKDGWYVVNQTPSV
HHHHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCEEEEEECCCCEECCCEEEEECCCCH
AGFVQKRYTEYSESLNKLVAWAYFNRILTANTDLHIISPNVSLTTLRHFVTDLRLSFPVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCEE
VSSVTNEDLTHACEIRSLIVAVNLTVDPTKKITQVKSRIQASDLFSFGPKEESLVGSIDI
EECCCCHHHHHHHHHEEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEH
TYRNLWNEIRTLHFEGPNAILLALKVLSNKIHRGAPSPKLIQVFSYSHRYRRTLSNIVTA
HHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LINRCISIQIGDALPPQNNLLRVAGKNWQFFFEERGISLQEIHSNEELEATGFDTALQTE
HHHHHEEEEECCCCCCCCCEEEEECCCCEEEEECCCCCHHHHCCCCCCCCCCCCHHHHHH
VEEKESALPDTSRTYPPEIDHFASEGFLQFFFEDNSDGSFNVYILDEANRIEIYRNCDGQ
HHHHHHCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCEEEEEEEECCCEEEEEECCCCH
KEKKILEINHIYQSSGLDENNNPYKIVQRDFNYPQFYQLLLQENGVKIVPFHSRLAMS
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1917858; 11248100; 8418825