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The map label for this gene is fruK [H]

Identifier: 15603661

GI number: 15603661

Start: 2022218

End: 2023153

Strand: Reverse

Name: fruK [H]

Synonym: PM1796

Alternate gene names: 15603661

Gene position: 2023153-2022218 (Counterclockwise)

Preceding gene: 15603662

Following gene: 15603660

Centisome position: 89.62

GC content: 44.87

Gene sequence:

>936_bases
ATGACAAAAGTACTGACCATTACACTAAATTCTGCCTACGACTTAGTAGGGCATCTCCCTCACCTAACACGAGGTGCTGT
AAACCAGGTGGATTCTTTAGGACTTTACCCTGCCGGCAAAGGGATTAATGTTGGCAAAGTTCTGCATGACTTAGGGGTAA
ACGTGGCATTAACGGGCTTTCTCGGGCAAGAAAATCAAACGGGATTTCAACAATTGTTTTCGCGTTTGGGGCTCACCGAT
CATTTTCATCGAATTACCGGCGCAACACGCATCAACGTAAAACTGACAGAGTCAGATGGCGTCGTCACTGACCTCAATTT
TCAAGGCTATCATGTGAGTAAGACAGATTGGCAAACGTTTGTGGACTTTTCATTGCAACAATGCCAAACATTTGATGTGA
TTGCAGTTTGTGGCAGCCTTCCTCGAGGAATCAGCGTAGATGACTTTACAGCTTGGCTCAGCCAACTTAATAAAAATAAC
ATCAAGCTCATATTAGACACCAGCCAACAAGCTTTCGCATCAGGCATACAAGCCAAACCTTGGCTCGTCAAACCCAATCG
CGATGAGCTTGCAAGCTGGTATGGTTCGCCATTAGCGACACAGCAAGACATCATCCGCGCGGCAACACTATTACAACGAC
AAGGTATCCCTCATGTCGTCGTTTCAATGGGGGAAGAAGGGGCAATTTGGCTAAATGAAAATACAGTGTTACACGCCCAG
CCCCCACAAGACACGCCTATCGTCAGTACCGTAGGCGCGGGAGATACCATGGTAGCGGGTCTAATTTATGGTATGCTTAA
TGCATATTCTGCTGAAAAAACATTGGCTTTTGCGACCGCACTTTCGAGCTTAGCAGTTTCACAAAGTAATGTAGGCATCA
CTGACTTGACGTTACTCAACCCAATTTTAGAAAAAATAAAAATCACATTCATTTAA

Upstream 100 bases:

>100_bases
AACAAGGACATCGTTTACGCTTTGTTGCCACTGGTGCAGAAGCACAGCAAGCCATACAATGTGTAGGTGAGCTTATTGAC
AACCATTTAGGTGAGACAGC

Downstream 100 bases:

>100_bases
GGATAATTTCATGAACATTTTTCTCACACAAAAAGAAGACATTGGCAATGCAAAAGTATTCTTATTGCATCAAGTTATCA
CAGCAGCCGCCCATCAACAA

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTKVLTITLNSAYDLVGHLPHLTRGAVNQVDSLGLYPAGKGINVGKVLHDLGVNVALTGFLGQENQTGFQQLFSRLGLTD
HFHRITGATRINVKLTESDGVVTDLNFQGYHVSKTDWQTFVDFSLQQCQTFDVIAVCGSLPRGISVDDFTAWLSQLNKNN
IKLILDTSQQAFASGIQAKPWLVKPNRDELASWYGSPLATQQDIIRAATLLQRQGIPHVVVSMGEEGAIWLNENTVLHAQ
PPQDTPIVSTVGAGDTMVAGLIYGMLNAYSAEKTLAFATALSSLAVSQSNVGITDLTLLNPILEKIKITFI

Sequences:

>Translated_311_residues
MTKVLTITLNSAYDLVGHLPHLTRGAVNQVDSLGLYPAGKGINVGKVLHDLGVNVALTGFLGQENQTGFQQLFSRLGLTD
HFHRITGATRINVKLTESDGVVTDLNFQGYHVSKTDWQTFVDFSLQQCQTFDVIAVCGSLPRGISVDDFTAWLSQLNKNN
IKLILDTSQQAFASGIQAKPWLVKPNRDELASWYGSPLATQQDIIRAATLLQRQGIPHVVVSMGEEGAIWLNENTVLHAQ
PPQDTPIVSTVGAGDTMVAGLIYGMLNAYSAEKTLAFATALSSLAVSQSNVGITDLTLLNPILEKIKITFI
>Mature_310_residues
TKVLTITLNSAYDLVGHLPHLTRGAVNQVDSLGLYPAGKGINVGKVLHDLGVNVALTGFLGQENQTGFQQLFSRLGLTDH
FHRITGATRINVKLTESDGVVTDLNFQGYHVSKTDWQTFVDFSLQQCQTFDVIAVCGSLPRGISVDDFTAWLSQLNKNNI
KLILDTSQQAFASGIQAKPWLVKPNRDELASWYGSPLATQQDIIRAATLLQRQGIPHVVVSMGEEGAIWLNENTVLHAQP
PQDTPIVSTVGAGDTMVAGLIYGMLNAYSAEKTLAFATALSSLAVSQSNVGITDLTLLNPILEKIKITFI

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=306, Percent_Identity=53.5947712418301, Blast_Score=320, Evalue=9e-89,
Organism=Escherichia coli, GI1788017, Length=293, Percent_Identity=26.6211604095563, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 33686; Mature: 33555

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVLTITLNSAYDLVGHLPHLTRGAVNQVDSLGLYPAGKGINVGKVLHDLGVNVALTGF
CCEEEEEEECCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEE
LGQENQTGFQQLFSRLGLTDHFHRITGATRINVKLTESDGVVTDLNFQGYHVSKTDWQTF
CCCCCCHHHHHHHHHCCCCHHHHHHCCCEEEEEEEECCCCEEEEECCCCEECCCCCHHHH
VDFSLQQCQTFDVIAVCGSLPRGISVDDFTAWLSQLNKNNIKLILDTSQQAFASGIQAKP
HHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCCCC
WLVKPNRDELASWYGSPLATQQDIIRAATLLQRQGIPHVVVSMGEEGAIWLNENTVLHAQ
EEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCEEEECC
PPQDTPIVSTVGAGDTMVAGLIYGMLNAYSAEKTLAFATALSSLAVSQSNVGITDLTLLN
CCCCCCCEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
PILEKIKITFI
HHHHHEEEECC
>Mature Secondary Structure 
TKVLTITLNSAYDLVGHLPHLTRGAVNQVDSLGLYPAGKGINVGKVLHDLGVNVALTGF
CEEEEEEECCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEE
LGQENQTGFQQLFSRLGLTDHFHRITGATRINVKLTESDGVVTDLNFQGYHVSKTDWQTF
CCCCCCHHHHHHHHHCCCCHHHHHHCCCEEEEEEEECCCCEEEEECCCCEECCCCCHHHH
VDFSLQQCQTFDVIAVCGSLPRGISVDDFTAWLSQLNKNNIKLILDTSQQAFASGIQAKP
HHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCCCC
WLVKPNRDELASWYGSPLATQQDIIRAATLLQRQGIPHVVVSMGEEGAIWLNENTVLHAQ
EEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCEEEECC
PPQDTPIVSTVGAGDTMVAGLIYGMLNAYSAEKTLAFATALSSLAVSQSNVGITDLTLLN
CCCCCCCEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
PILEKIKITFI
HHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]