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The map label for this gene is slpA [H]

Identifier: 15603634

GI number: 15603634

Start: 1994906

End: 1996159

Strand: Direct

Name: slpA [H]

Synonym: PM1769

Alternate gene names: 15603634

Gene position: 1994906-1996159 (Clockwise)

Preceding gene: 15603632

Following gene: 15603635

Centisome position: 88.37

GC content: 41.87

Gene sequence:

>1254_bases
ATGGCTAGATTAGTGAAGAAACTAACAGACAGCGAGATTAAAAACGCAAAAGCGACAAGCAAACCACTATATGATGGTGA
GGGGCTATTTTTAGAAGTATCAAGTAAAGGGGCGAAATTATGGCGTTTTAGATACGCCCAGCCTTACACTAAGAAACGCA
CTACAATTAGCTTGGGTACTTACCCTGATTTATCACTATCACAAGCCAGAGCCAAGCGCGATGAATTTAATGCCTTGCTG
GCGAATAATATCGATCCGCAAACTTACCGTAAGCAACAAGAACAAGCACAAGCGGACAGGCTAAGCCGTACCTTTGATAA
AATGGCTAAGGCGTGGTTTGAAGATAGAAAAATCAAAGCTAACTTTTCAGAGCGCACCGCCAAAGATACATGGGCTTTAT
TTGAACGCCATTTACTCCCACACTTTGCTAATTATCCAATCACAGAAATCACGCCACTTATCGCCATTAATGCGCTTAAA
CCACTAGAGAAAGAGGGCAAGTTAGAAACCGTTAAAAAGACTATTGGCAACCTTAACAATGTGATGAGGTTCGCACTTCA
TAGGGGATTGATCCCGCATAATCCATTAGCAGAAATAGGCAAGGAATTTGATAAGCCAGTCTCTAAGGGAATGAATACCA
TTACCCCTGAAGAATTAAGCGAGTTCTTACACGGCTTTTACCGGGCAAGAGATGAAAACCGCTTTAATCCGTTTTCATTT
TATGCGGTTATGCTAGTGGTATTGACTGGTGGGAGACCGTCCGAAATAGCCAAAGCGAAATGGGCGGATATTAATTACAA
GGAAAAAACGTGGACTTACCGAGTACAAAAGGGCAATAAAAATCTACCTGAGGGGCGAGAACACGTAGTAACACTATCAC
ACCAAGCAATTGGGATATTTAACAAAATGCAACATTTACACACCGCACTTGGCATTGAGAGTGAATTTGTGTTTGCCAGT
TTAACAGCGAAAAGCGGGCATTTAAGCATTGAAACAATGCGAAAAGCCATTATCAAGGGGATAGGGGAAAATCGCCTCAC
TACGCACGGCATACGCCATTTATTCAGCACGTCATTAAATGAGAAAGACTACAAAGCCGACTGGATAGAAAGAGCCTTAT
CACACAAGCAAAATAAAGATAAAAACCAAATCCGCAGAACCTATGATAAATCCTTGTATCTCTCACAAAGGGCGGTGATG
TTACAAGAATGGGCGGATTATGTAGAAAGCCAAGCGCCAGAGCCAATTGTATAA

Upstream 100 bases:

>100_bases
AAGGTTTGGATGGGTTTAGTACTATAATTTGATCATTCAAAAAATAGTACTATCTTGAGTAGGCTTTCTAAAAATAACTC
TTTTTACATGGAGTTTTTTT

Downstream 100 bases:

>100_bases
ATAGGATATTGTAGGGATAATCGTTTGATTTAAAGATAAAAATAAACTAGGATTCCAGATAATTTTTAAAGTTTTTTTAA
TTGAGATTAAAGGGGAGTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MARLVKKLTDSEIKNAKATSKPLYDGEGLFLEVSSKGAKLWRFRYAQPYTKKRTTISLGTYPDLSLSQARAKRDEFNALL
ANNIDPQTYRKQQEQAQADRLSRTFDKMAKAWFEDRKIKANFSERTAKDTWALFERHLLPHFANYPITEITPLIAINALK
PLEKEGKLETVKKTIGNLNNVMRFALHRGLIPHNPLAEIGKEFDKPVSKGMNTITPEELSEFLHGFYRARDENRFNPFSF
YAVMLVVLTGGRPSEIAKAKWADINYKEKTWTYRVQKGNKNLPEGREHVVTLSHQAIGIFNKMQHLHTALGIESEFVFAS
LTAKSGHLSIETMRKAIIKGIGENRLTTHGIRHLFSTSLNEKDYKADWIERALSHKQNKDKNQIRRTYDKSLYLSQRAVM
LQEWADYVESQAPEPIV

Sequences:

>Translated_417_residues
MARLVKKLTDSEIKNAKATSKPLYDGEGLFLEVSSKGAKLWRFRYAQPYTKKRTTISLGTYPDLSLSQARAKRDEFNALL
ANNIDPQTYRKQQEQAQADRLSRTFDKMAKAWFEDRKIKANFSERTAKDTWALFERHLLPHFANYPITEITPLIAINALK
PLEKEGKLETVKKTIGNLNNVMRFALHRGLIPHNPLAEIGKEFDKPVSKGMNTITPEELSEFLHGFYRARDENRFNPFSF
YAVMLVVLTGGRPSEIAKAKWADINYKEKTWTYRVQKGNKNLPEGREHVVTLSHQAIGIFNKMQHLHTALGIESEFVFAS
LTAKSGHLSIETMRKAIIKGIGENRLTTHGIRHLFSTSLNEKDYKADWIERALSHKQNKDKNQIRRTYDKSLYLSQRAVM
LQEWADYVESQAPEPIV
>Mature_416_residues
ARLVKKLTDSEIKNAKATSKPLYDGEGLFLEVSSKGAKLWRFRYAQPYTKKRTTISLGTYPDLSLSQARAKRDEFNALLA
NNIDPQTYRKQQEQAQADRLSRTFDKMAKAWFEDRKIKANFSERTAKDTWALFERHLLPHFANYPITEITPLIAINALKP
LEKEGKLETVKKTIGNLNNVMRFALHRGLIPHNPLAEIGKEFDKPVSKGMNTITPEELSEFLHGFYRARDENRFNPFSFY
AVMLVVLTGGRPSEIAKAKWADINYKEKTWTYRVQKGNKNLPEGREHVVTLSHQAIGIFNKMQHLHTALGIESEFVFASL
TAKSGHLSIETMRKAIIKGIGENRLTTHGIRHLFSTSLNEKDYKADWIERALSHKQNKDKNQIRRTYDKSLYLSQRAVML
QEWADYVESQAPEPIV

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=419, Percent_Identity=37.4701670644391, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI145693166, Length=410, Percent_Identity=31.7073170731707, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788690, Length=409, Percent_Identity=26.8948655256724, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 47983; Mature: 47852

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLVKKLTDSEIKNAKATSKPLYDGEGLFLEVSSKGAKLWRFRYAQPYTKKRTTISLGT
CHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEHEEECCCCCCCCCCEEEECC
YPDLSLSQARAKRDEFNALLANNIDPQTYRKQQEQAQADRLSRTFDKMAKAWFEDRKIKA
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEC
NFSERTAKDTWALFERHLLPHFANYPITEITPLIAINALKPLEKEGKLETVKKTIGNLNN
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
VMRFALHRGLIPHNPLAEIGKEFDKPVSKGMNTITPEELSEFLHGFYRARDENRFNPFSF
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHH
YAVMLVVLTGGRPSEIAKAKWADINYKEKTWTYRVQKGNKNLPEGREHVVTLSHQAIGIF
HHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCHHEEEECHHHHHHH
NKMQHLHTALGIESEFVFASLTAKSGHLSIETMRKAIIKGIGENRLTTHGIRHLFSTSLN
HHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
EKDYKADWIERALSHKQNKDKNQIRRTYDKSLYLSQRAVMLQEWADYVESQAPEPIV
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ARLVKKLTDSEIKNAKATSKPLYDGEGLFLEVSSKGAKLWRFRYAQPYTKKRTTISLGT
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEHEEECCCCCCCCCCEEEECC
YPDLSLSQARAKRDEFNALLANNIDPQTYRKQQEQAQADRLSRTFDKMAKAWFEDRKIKA
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEC
NFSERTAKDTWALFERHLLPHFANYPITEITPLIAINALKPLEKEGKLETVKKTIGNLNN
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
VMRFALHRGLIPHNPLAEIGKEFDKPVSKGMNTITPEELSEFLHGFYRARDENRFNPFSF
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHH
YAVMLVVLTGGRPSEIAKAKWADINYKEKTWTYRVQKGNKNLPEGREHVVTLSHQAIGIF
HHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCHHEEEECHHHHHHH
NKMQHLHTALGIESEFVFASLTAKSGHLSIETMRKAIIKGIGENRLTTHGIRHLFSTSLN
HHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
EKDYKADWIERALSHKQNKDKNQIRRTYDKSLYLSQRAVMLQEWADYVESQAPEPIV
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]