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The map label for this gene is siaT [H]

Identifier: 15603507

GI number: 15603507

Start: 1851428

End: 1852720

Strand: Reverse

Name: siaT [H]

Synonym: PM1642

Alternate gene names: 15603507

Gene position: 1852720-1851428 (Counterclockwise)

Preceding gene: 15603508

Following gene: 15603506

Centisome position: 82.07

GC content: 36.58

Gene sequence:

>1293_bases
ATGTCATTCATTCTTTTATTAGGGACAATGTTTTTATTAACAGTTTTTGGCTTGCCACTATTTTATAGTATTATTTTTGC
TTCAATTGTGACATTGTTTTATTTCTTACCTAATATCCCTGTTACGATTGTTGCACAACAAGTGATGCAAGGGTTAGACA
CCAATGCATTACAAGCACTCGCATTTTTCTTTTTAGCCGGTGAACTGATGAGTGTGGGCGGCATAACTAATCGTATTATT
CGATTTGTCACCTCGATAATTGGTCGTTGGAAAGGTTCTCTGGCATATATCAATATTTTCTCCAGTTTATTTTTTGGTTC
TATCAGTGGCTCCGCTGTGGCATCTACTGCCGCGATTGGAAGCTCATTAATCCCTGAAATGAAAAAAAGAGGTTATCCCG
CCCCTTTTTCTGCAGCATTAACGCAGTCGGCTTCTATCATTGGTCCCATTATTCCGCCTAGTGTGCCGATGATTGTATTT
GCTGCATTAGCAGGAGCAGGTGTTTCCGTTGGGAAGATGTTTATGTCTGGGATTATTCCTGGGCTTATGATCGCATTAAC
ATTAATTTTAATTACGTTCATCATTTCAAAAATTAAAGGCTATGGTAATCATTCAGTAGAATTTAGCCTCAAAGAAGTTA
AAGAAAGCGCGAAAGATGCAGTATGGGCGTTACTCTGTCCGATTATCATTCTCTATGGCATTATTTCAGGTATTTTTACG
GCAACAGAAGCAGGCGCAGTTTCGGTCGTTTATGCCTATTTAATTGGTACGTTTGTTTATAAAGAATTAAATCTGGAACG
ATTAAAGAAAGCTTTTATTTCTTCTTTAAAAGGTACCATTACAGTAATGTTAATTGTTGGCGCGTCTTCTATTTTTGCGT
GGATGATTGCGCGTTTGCAAATCAGCCATCAAGTCGCAAGTTGGGTATCTTCTGTGTGCAGTAGCCCATTAGAGGCGCTT
ATTCTTATTAATGTGATTGTTCTTTTTATTGGCATGATAATGGATCCTACCGCGGCATTAACCATTTTAGTTCCTGTATT
TATGCCGATCGTTAATCAATTTGGTATTTCACCTATTCATTTTGGATTAGTTGTTATTTTAAATCTGATGATAGGTCTCA
TTACCCCGCCTGTCGGTTATTTAATATTCTTGTCAGCAAATATCGCAGAGTGTGAACCCATTAAGGTATTGAAAGAAAGT
TTACCTTTTTTACTGTCATTACTAGGTTTACTTATTTTACTCATTTTAGTACCTGAATTTAGTACATTCTTACCCGATTT
ATTATTTAAATAA

Upstream 100 bases:

>100_bases
GGGTTTATGTGCCATTTATTATTTGTTTATCTCTAGAAGCATTCAGAATTGTATTGGCTTTAATTGCGTTAATTCAAACT
AAAAAAGTGAGGGATCTATA

Downstream 100 bases:

>100_bases
GGAGTAAATCATGAGTAACTGGATTGATTTATCAATGCCGATTGCTAACAACCATGTGCGTTGGCAAACCCATATTGAGA
AAAAAGGTAATTTTGATTCG

Product: hypothetical protein

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MSFILLLGTMFLLTVFGLPLFYSIIFASIVTLFYFLPNIPVTIVAQQVMQGLDTNALQALAFFFLAGELMSVGGITNRII
RFVTSIIGRWKGSLAYINIFSSLFFGSISGSAVASTAAIGSSLIPEMKKRGYPAPFSAALTQSASIIGPIIPPSVPMIVF
AALAGAGVSVGKMFMSGIIPGLMIALTLILITFIISKIKGYGNHSVEFSLKEVKESAKDAVWALLCPIIILYGIISGIFT
ATEAGAVSVVYAYLIGTFVYKELNLERLKKAFISSLKGTITVMLIVGASSIFAWMIARLQISHQVASWVSSVCSSPLEAL
ILINVIVLFIGMIMDPTAALTILVPVFMPIVNQFGISPIHFGLVVILNLMIGLITPPVGYLIFLSANIAECEPIKVLKES
LPFLLSLLGLLILLILVPEFSTFLPDLLFK

Sequences:

>Translated_430_residues
MSFILLLGTMFLLTVFGLPLFYSIIFASIVTLFYFLPNIPVTIVAQQVMQGLDTNALQALAFFFLAGELMSVGGITNRII
RFVTSIIGRWKGSLAYINIFSSLFFGSISGSAVASTAAIGSSLIPEMKKRGYPAPFSAALTQSASIIGPIIPPSVPMIVF
AALAGAGVSVGKMFMSGIIPGLMIALTLILITFIISKIKGYGNHSVEFSLKEVKESAKDAVWALLCPIIILYGIISGIFT
ATEAGAVSVVYAYLIGTFVYKELNLERLKKAFISSLKGTITVMLIVGASSIFAWMIARLQISHQVASWVSSVCSSPLEAL
ILINVIVLFIGMIMDPTAALTILVPVFMPIVNQFGISPIHFGLVVILNLMIGLITPPVGYLIFLSANIAECEPIKVLKES
LPFLLSLLGLLILLILVPEFSTFLPDLLFK
>Mature_429_residues
SFILLLGTMFLLTVFGLPLFYSIIFASIVTLFYFLPNIPVTIVAQQVMQGLDTNALQALAFFFLAGELMSVGGITNRIIR
FVTSIIGRWKGSLAYINIFSSLFFGSISGSAVASTAAIGSSLIPEMKKRGYPAPFSAALTQSASIIGPIIPPSVPMIVFA
ALAGAGVSVGKMFMSGIIPGLMIALTLILITFIISKIKGYGNHSVEFSLKEVKESAKDAVWALLCPIIILYGIISGIFTA
TEAGAVSVVYAYLIGTFVYKELNLERLKKAFISSLKGTITVMLIVGASSIFAWMIARLQISHQVASWVSSVCSSPLEALI
LINVIVLFIGMIMDPTAALTILVPVFMPIVNQFGISPIHFGLVVILNLMIGLITPPVGYLIFLSANIAECEPIKVLKESL
PFLLSLLGLLILLILVPEFSTFLPDLLFK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=419, Percent_Identity=35.799522673031, Blast_Score=219, Evalue=4e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 46205; Mature: 46073

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCC
>Mature Secondary Structure 
SFILLLGTMFLLTVFGLPLFYSIIFASIVTLFYFLPNIPVTIVAQQVMQGLDTNALQAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHH
AFFFLAGELMSVGGITNRIIRFVTSIIGRWKGSLAYINIFSSLFFGSISGSAVASTAAIG
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
SSLIPEMKKRGYPAPFSAALTQSASIIGPIIPPSVPMIVFAALAGAGVSVGKMFMSGIIP
HHHHHHHHHCCCCCCHHHHHHHCHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
GLMIALTLILITFIISKIKGYGNHSVEFSLKEVKESAKDAVWALLCPIIILYGIISGIFT
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATEAGAVSVVYAYLIGTFVYKELNLERLKKAFISSLKGTITVMLIVGASSIFAWMIARLQ
HHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISHQVASWVSSVCSSPLEALILINVIVLFIGMIMDPTAALTILVPVFMPIVNQFGISPIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHH
FGLVVILNLMIGLITPPVGYLIFLSANIAECEPIKVLKESLPFLLSLLGLLILLILVPEF
HHHHHHHHHHHHHHCCCHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STFLPDLLFK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]