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The map label for this gene is udp [H]

Identifier: 15603437

GI number: 15603437

Start: 1781242

End: 1782000

Strand: Reverse

Name: udp [H]

Synonym: PM1572

Alternate gene names: 15603437

Gene position: 1782000-1781242 (Counterclockwise)

Preceding gene: 15603438

Following gene: 15603436

Centisome position: 78.94

GC content: 44.4

Gene sequence:

>759_bases
ATGTCAGAAGTATTCCATCTAGGTTTAACCAAAGCGATGTTAGAAGGCGCCACTTTAGCGATTACCCCAGGCGCCCCAGA
ACGTGTCGAAAAAATTGCCAAGCTTTTAGATCGTCCAAAATTTTTAGCATCGACCCGTGAATTCACCTCTTGGCTCGGTT
ATATCGGAGATAAAGCTGTTGTCGTCTGTTCCACAGGGATCGGTGGACCTTCAGTTTCTATCGCCGTTGAAGAACTGGCA
CAATTAGGTGTTCGCACCTTCTTACGCATTGGCACAACCGGCGCAATTCAACCACACATCAATGTTGGCGATATTCTTGT
CACCACAGGCGCAGTACGCTTAGACGGAGCAAGTTTACACTTTGCCCCAATGGAGTACCCTGCGGTTGCTAATTTTGAAT
GTACTAATGCGCTTTACAAAGCTGCTACAGAATTAGCCAACCAAAAAGTATATGTGGGTATTACTGCTGCATCAGATACA
TTCTACCCAGGTCAAGAACGTTATGATACGTACAGTGGTAAAGTCTATCGCCACTTCCAAGGTTCATTAAAACAATGGCA
AGATCTTAATGTCATGAACTTTGAAATGGAATCTGCCACCTTATTTACGATGTGTTCTGCGTTAGGTTTACGCGCTGGTA
TGGTTGCGGGTGCCATTGTTAACCGTACACAGCAAGAGATCCCAAATGAAGCCGCAGTGAAAGATATTGAAAAAAATGCA
GTTGAAATTGTCGTCAAAGCCGCGGCGTATCTACTTTAA

Upstream 100 bases:

>100_bases
CAGTTAATTGATGAAATTCAATCGACTGAGACCTTAATCTCAATGCAAAATCCAATTTTGCGTGATATTAAACCCTAGCA
TAATAAAATAAGGAGATATT

Downstream 100 bases:

>100_bases
TTTTTCATTCCCTTTACATAAAACGCTTAGCTATCGTCTAAGCGTTTTTTATTTCAAGAAATTGTCTATTTTCAGTGATT
TTATCGCCACTCTTTGCTTT

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSEVFHLGLTKAMLEGATLAITPGAPERVEKIAKLLDRPKFLASTREFTSWLGYIGDKAVVVCSTGIGGPSVSIAVEELA
QLGVRTFLRIGTTGAIQPHINVGDILVTTGAVRLDGASLHFAPMEYPAVANFECTNALYKAATELANQKVYVGITAASDT
FYPGQERYDTYSGKVYRHFQGSLKQWQDLNVMNFEMESATLFTMCSALGLRAGMVAGAIVNRTQQEIPNEAAVKDIEKNA
VEIVVKAAAYLL

Sequences:

>Translated_252_residues
MSEVFHLGLTKAMLEGATLAITPGAPERVEKIAKLLDRPKFLASTREFTSWLGYIGDKAVVVCSTGIGGPSVSIAVEELA
QLGVRTFLRIGTTGAIQPHINVGDILVTTGAVRLDGASLHFAPMEYPAVANFECTNALYKAATELANQKVYVGITAASDT
FYPGQERYDTYSGKVYRHFQGSLKQWQDLNVMNFEMESATLFTMCSALGLRAGMVAGAIVNRTQQEIPNEAAVKDIEKNA
VEIVVKAAAYLL
>Mature_251_residues
SEVFHLGLTKAMLEGATLAITPGAPERVEKIAKLLDRPKFLASTREFTSWLGYIGDKAVVVCSTGIGGPSVSIAVEELAQ
LGVRTFLRIGTTGAIQPHINVGDILVTTGAVRLDGASLHFAPMEYPAVANFECTNALYKAATELANQKVYVGITAASDTF
YPGQERYDTYSGKVYRHFQGSLKQWQDLNVMNFEMESATLFTMCSALGLRAGMVAGAIVNRTQQEIPNEAAVKDIEKNAV
EIVVKAAAYLL

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=251, Percent_Identity=71.7131474103586, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI1790844, Length=209, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 27184; Mature: 27052

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVFHLGLTKAMLEGATLAITPGAPERVEKIAKLLDRPKFLASTREFTSWLGYIGDKAV
CCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEE
VVCSTGIGGPSVSIAVEELAQLGVRTFLRIGTTGAIQPHINVGDILVTTGAVRLDGASLH
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCEEEECCCEEE
FAPMEYPAVANFECTNALYKAATELANQKVYVGITAASDTFYPGQERYDTYSGKVYRHFQ
ECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHCCCCCCHHHHHHH
GSLKQWQDLNVMNFEMESATLFTMCSALGLRAGMVAGAIVNRTQQEIPNEAAVKDIEKNA
HHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VEIVVKAAAYLL
HHHHHHHHHHCC
>Mature Secondary Structure 
SEVFHLGLTKAMLEGATLAITPGAPERVEKIAKLLDRPKFLASTREFTSWLGYIGDKAV
CCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEE
VVCSTGIGGPSVSIAVEELAQLGVRTFLRIGTTGAIQPHINVGDILVTTGAVRLDGASLH
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCEEEECCCEEE
FAPMEYPAVANFECTNALYKAATELANQKVYVGITAASDTFYPGQERYDTYSGKVYRHFQ
ECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHCCCCCCHHHHHHH
GSLKQWQDLNVMNFEMESATLFTMCSALGLRAGMVAGAIVNRTQQEIPNEAAVKDIEKNA
HHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VEIVVKAAAYLL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]