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The map label for this gene is yfkJ [H]

Identifier: 15603434

GI number: 15603434

Start: 1775043

End: 1775513

Strand: Reverse

Name: yfkJ [H]

Synonym: PM1569

Alternate gene names: 15603434

Gene position: 1775513-1775043 (Counterclockwise)

Preceding gene: 15603435

Following gene: 15603433

Centisome position: 78.65

GC content: 40.13

Gene sequence:

>471_bases
ATGACAATTCATCTTTTATTTGTTTGCTTAGGTAACATTTGTCGTTCACCTATGGCGGAATTTCTGATGCGTGAGAAAAT
TAAGCAGGCTGGATTGGAAACGGTAATAAAAACCAGTAGTGCAGGAACATCTGGTTGGCATGACGGTGAAGATATGCATT
GTGGAACGGCGGATATATTAGATCAATGTCATATTGATAGCACAGGCTTTCGTAGCAAAAAAGTCCAGCGCCAGCACTGG
CAAGAATTTGATTATATTATCGCGATGGATAACAGTAATCTGCAAGACTTAGAGCGCCTTTTCGGTCATCATCCTGATAA
GCTTTTCAAAATAACCGAGCTTTGTCCTGATTTAGGTTATGATCATATTCCTGACCCTTGGTATAGCAAAGATTTTAACC
AAACCTATCAGCTACTCAATCCATGTTGCGATGCCCTGTTAGCGAGGCTACGTGAAAAACATCATCTATAA

Upstream 100 bases:

>100_bases
TAAAAACATGTAACCTAAATTCGGCTCTATTCGATTTTATTGAATAGAGCCGAATTGTATTTTATTGCGATAAAAATAAA
GTCAGGAAAAGGAAAGTAAC

Downstream 100 bases:

>100_bases
ATTTGTGATCTCTAACACAGTAATTGAGAACGAATTTCGATAAGATAACAATGTGTATAGTTTTTATACTTTAACCTGAT
ATGAAAGGAGCAACCTATGT

Product: YfkJ

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MTIHLLFVCLGNICRSPMAEFLMREKIKQAGLETVIKTSSAGTSGWHDGEDMHCGTADILDQCHIDSTGFRSKKVQRQHW
QEFDYIIAMDNSNLQDLERLFGHHPDKLFKITELCPDLGYDHIPDPWYSKDFNQTYQLLNPCCDALLARLREKHHL

Sequences:

>Translated_156_residues
MTIHLLFVCLGNICRSPMAEFLMREKIKQAGLETVIKTSSAGTSGWHDGEDMHCGTADILDQCHIDSTGFRSKKVQRQHW
QEFDYIIAMDNSNLQDLERLFGHHPDKLFKITELCPDLGYDHIPDPWYSKDFNQTYQLLNPCCDALLARLREKHHL
>Mature_155_residues
TIHLLFVCLGNICRSPMAEFLMREKIKQAGLETVIKTSSAGTSGWHDGEDMHCGTADILDQCHIDSTGFRSKKVQRQHWQ
EFDYIIAMDNSNLQDLERLFGHHPDKLFKITELCPDLGYDHIPDPWYSKDFNQTYQLLNPCCDALLARLREKHHL

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=159, Percent_Identity=36.4779874213836, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI6005988, Length=155, Percent_Identity=33.5483870967742, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6325330, Length=156, Percent_Identity=32.6923076923077, Blast_Score=81, Evalue=6e-17,
Organism=Drosophila melanogaster, GI78706770, Length=167, Percent_Identity=31.1377245508982, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI78706772, Length=167, Percent_Identity=31.1377245508982, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI78706766, Length=156, Percent_Identity=31.4102564102564, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI78706768, Length=156, Percent_Identity=31.4102564102564, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI78706764, Length=138, Percent_Identity=32.6086956521739, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI78711846, Length=148, Percent_Identity=34.4594594594595, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18061; Mature: 17930

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIHLLFVCLGNICRSPMAEFLMREKIKQAGLETVIKTSSAGTSGWHDGEDMHCGTADIL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
DQCHIDSTGFRSKKVQRQHWQEFDYIIAMDNSNLQDLERLFGHHPDKLFKITELCPDLGY
HHHCCCCCCCHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHCCC
DHIPDPWYSKDFNQTYQLLNPCCDALLARLREKHHL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIHLLFVCLGNICRSPMAEFLMREKIKQAGLETVIKTSSAGTSGWHDGEDMHCGTADIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
DQCHIDSTGFRSKKVQRQHWQEFDYIIAMDNSNLQDLERLFGHHPDKLFKITELCPDLGY
HHHCCCCCCCHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHCCC
DHIPDPWYSKDFNQTYQLLNPCCDALLARLREKHHL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]