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The map label for this gene is hsdA

Identifier: 15603403

GI number: 15603403

Start: 1737837

End: 1739144

Strand: Direct

Name: hsdA

Synonym: PM1538

Alternate gene names: NA

Gene position: 1737837-1739144 (Clockwise)

Preceding gene: 15603402

Following gene: 15603404

Centisome position: 76.98

GC content: 35.7

Gene sequence:

>1308_bases
TTGGAGGATATAGTAAATTTTTTAAATGCGAAACGAAAACCTTTAAGCGCTAAGGAAAGAGAAAATAGAAAAGGAATATA
TCCATATTATGGTGCTTCAGATATTGTTGATTATATAGATGATTATATTTTTGATGGTAGGTATTTACTTATTTCAGAAG
ATGGAGAAAATCTAAAAACAAGAAAAACCCCAATAGCTTTTATCGCGGAAGGAAAATTTTGGGTTAATAATCATGCCCAT
ATAATTTCAGGAAAAGATGATCAAACAATAGACTATTTGAAATATTATTTTTCAAATTTTGATTTGATGCCTTTTTTGAC
AGGTGCGGTACAGCCAAAATTAAGTAAAGGAATTTTAGAAAAAATTGAGATTGATTTTCCTTGTTATGAAAAAAGAAAAA
GGGTTAATCAATTTCTTGGCAGTTTAGATAATAAAATTGATTTAAACACCCAAACCAACCAAACCCTCGAACAAATCGCC
CAAGCAATTTTTAAAAGCTGGTTTGTGGATTTTGACCCTGTCAAAGCCAAAGTGGACGTCCTCGCTAATGGTGGTAGCCA
AGCCGACGCCGAACGCGCCGCAATGCAAGTGATTTCCGGCAAAACCGACGCCGAACTCACCCAAATGCAACAAACCCAAC
CCGACGCTTACAAAACGCTCGAAAAAAACACCGCACTTTTCCCCAGCGAAATGGTGGAAAGTGAGTTGGGCAACGTGCCG
AAGGGGTGGGGGGTCAGTACCATAGGTGATTCAGTTCAAACTGTTGGAGGAGCAACACCCTCAACAACAAATGAAGAATT
TTGGAGTAACGGTCATATTCATTGGACAACCCCTAAAGATTTATCTTCAGCAAAAGACAAAATATTATTAAACACGGATC
GTAAAATAACAGAAGCGGGTTTGAAAAAAATCAGTTCAGGATTATTACCTATAAATACAGTGTTACTTTCCTCTAGAGCG
CCGGTTGGATATTTAGCATTAACTCGAATTCCGGTAGCAATCAATCAGGGATATATTGGTATTATTTGTTCAGATAAATT
GAGTTGTTATTACGTTTTGCAGTGGTGTCAAGCTAACTTGGATGAAATAAAAGGCAGGGCCAGTGGTACAACCTTCGCAG
AGATAAATAAAAAAACATTTAGAGAAATGCGCGTTCTTATTCCAAATAATGAGTTGATCAAAGTTTACGACTTACAAGTT
GAAAAGTTATATAAAAAAATTACAGAGAATATTATAGAAAGTAAAGCATTAGAGAACATCAGAGACGCTTTATTACCAAA
ATTGCTTTCTGGAGAATTACATATTTAA

Upstream 100 bases:

>100_bases
ACCGCACTTTTAAACCAACAAATGACAGAAGGCGAACGCTTAAATGCCGAGATTAAAAAGAATCTAGCGGGGTTGGGGTA
TGAGTAGTTCAAAAGTAAAA

Downstream 100 bases:

>100_bases
ATATAATTTTTACCATCGCCAAGGAAATTAGTATATGTCGGAACATAACAAAACATTTAATAATGAAGTAATGCCGTTGT
GGAATCAAATTCTAGAAACA

Product: HsdA

Products: NA

Alternate protein names: S.HindVIIP; Type I restriction enzyme HindVIIP specificity protein; S protein [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MEDIVNFLNAKRKPLSAKERENRKGIYPYYGASDIVDYIDDYIFDGRYLLISEDGENLKTRKTPIAFIAEGKFWVNNHAH
IISGKDDQTIDYLKYYFSNFDLMPFLTGAVQPKLSKGILEKIEIDFPCYEKRKRVNQFLGSLDNKIDLNTQTNQTLEQIA
QAIFKSWFVDFDPVKAKVDVLANGGSQADAERAAMQVISGKTDAELTQMQQTQPDAYKTLEKNTALFPSEMVESELGNVP
KGWGVSTIGDSVQTVGGATPSTTNEEFWSNGHIHWTTPKDLSSAKDKILLNTDRKITEAGLKKISSGLLPINTVLLSSRA
PVGYLALTRIPVAINQGYIGIICSDKLSCYYVLQWCQANLDEIKGRASGTTFAEINKKTFREMRVLIPNNELIKVYDLQV
EKLYKKITENIIESKALENIRDALLPKLLSGELHI

Sequences:

>Translated_435_residues
MEDIVNFLNAKRKPLSAKERENRKGIYPYYGASDIVDYIDDYIFDGRYLLISEDGENLKTRKTPIAFIAEGKFWVNNHAH
IISGKDDQTIDYLKYYFSNFDLMPFLTGAVQPKLSKGILEKIEIDFPCYEKRKRVNQFLGSLDNKIDLNTQTNQTLEQIA
QAIFKSWFVDFDPVKAKVDVLANGGSQADAERAAMQVISGKTDAELTQMQQTQPDAYKTLEKNTALFPSEMVESELGNVP
KGWGVSTIGDSVQTVGGATPSTTNEEFWSNGHIHWTTPKDLSSAKDKILLNTDRKITEAGLKKISSGLLPINTVLLSSRA
PVGYLALTRIPVAINQGYIGIICSDKLSCYYVLQWCQANLDEIKGRASGTTFAEINKKTFREMRVLIPNNELIKVYDLQV
EKLYKKITENIIESKALENIRDALLPKLLSGELHI
>Mature_435_residues
MEDIVNFLNAKRKPLSAKERENRKGIYPYYGASDIVDYIDDYIFDGRYLLISEDGENLKTRKTPIAFIAEGKFWVNNHAH
IISGKDDQTIDYLKYYFSNFDLMPFLTGAVQPKLSKGILEKIEIDFPCYEKRKRVNQFLGSLDNKIDLNTQTNQTLEQIA
QAIFKSWFVDFDPVKAKVDVLANGGSQADAERAAMQVISGKTDAELTQMQQTQPDAYKTLEKNTALFPSEMVESELGNVP
KGWGVSTIGDSVQTVGGATPSTTNEEFWSNGHIHWTTPKDLSSAKDKILLNTDRKITEAGLKKISSGLLPINTVLLSSRA
PVGYLALTRIPVAINQGYIGIICSDKLSCYYVLQWCQANLDEIKGRASGTTFAEINKKTFREMRVLIPNNELIKVYDLQV
EKLYKKITENIIESKALENIRDALLPKLLSGELHI

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity [H]

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 48927; Mature: 48927

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDIVNFLNAKRKPLSAKERENRKGIYPYYGASDIVDYIDDYIFDGRYLLISEDGENLKT
CHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCC
RKTPIAFIAEGKFWVNNHAHIISGKDDQTIDYLKYYFSNFDLMPFLTGAVQPKLSKGILE
CCCCEEEEECCEEEECCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHH
KIEIDFPCYEKRKRVNQFLGSLDNKIDLNTQTNQTLEQIAQAIFKSWFVDFDPVKAKVDV
HHCCCCCHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEE
LANGGSQADAERAAMQVISGKTDAELTQMQQTQPDAYKTLEKNTALFPSEMVESELGNVP
EECCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHCCCC
KGWGVSTIGDSVQTVGGATPSTTNEEFWSNGHIHWTTPKDLSSAKDKILLNTDRKITEAG
CCCCCHHHCCHHHHHCCCCCCCCCHHHHCCCCEEECCCHHHHHCCCEEEECCCCHHHHHH
LKKISSGLLPINTVLLSSRAPVGYLALTRIPVAINQGYIGIICSDKLSCYYVLQWCQANL
HHHHHCCCCCHHHHHCCCCCCCCEEHHHHCCEEECCCEEEEEECCCCCHHHHHHHHHCCH
DEIKGRASGTTFAEINKKTFREMRVLIPNNELIKVYDLQVEKLYKKITENIIESKALENI
HHHCCCCCCCCHHHHHHHHHHHHEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
RDALLPKLLSGELHI
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MEDIVNFLNAKRKPLSAKERENRKGIYPYYGASDIVDYIDDYIFDGRYLLISEDGENLKT
CHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCC
RKTPIAFIAEGKFWVNNHAHIISGKDDQTIDYLKYYFSNFDLMPFLTGAVQPKLSKGILE
CCCCEEEEECCEEEECCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHH
KIEIDFPCYEKRKRVNQFLGSLDNKIDLNTQTNQTLEQIAQAIFKSWFVDFDPVKAKVDV
HHCCCCCHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEE
LANGGSQADAERAAMQVISGKTDAELTQMQQTQPDAYKTLEKNTALFPSEMVESELGNVP
EECCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHCCCC
KGWGVSTIGDSVQTVGGATPSTTNEEFWSNGHIHWTTPKDLSSAKDKILLNTDRKITEAG
CCCCCHHHCCHHHHHCCCCCCCCCHHHHCCCCEEECCCHHHHHCCCEEEECCCCHHHHHH
LKKISSGLLPINTVLLSSRAPVGYLALTRIPVAINQGYIGIICSDKLSCYYVLQWCQANL
HHHHHCCCCCHHHHHCCCCCCCCEEHHHHCCEEECCCEEEEEECCCCCHHHHHHHHHCCH
DEIKGRASGTTFAEINKKTFREMRVLIPNNELIKVYDLQVEKLYKKITENIIESKALENI
HHHCCCCCCCCHHHHHHHHHHHHEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
RDALLPKLLSGELHI
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]