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The map label for this gene is atpA [H]

Identifier: 15603357

GI number: 15603357

Start: 1682897

End: 1684438

Strand: Direct

Name: atpA [H]

Synonym: PM1492

Alternate gene names: 15603357

Gene position: 1682897-1684438 (Clockwise)

Preceding gene: 15603356

Following gene: 15603358

Centisome position: 74.55

GC content: 39.95

Gene sequence:

>1542_bases
ATGCAACTAAATTCTACAGAAATTAGTGAATTGATTAAAAAACGCATTGCCCAATTCGATGTTGTGAGTGAAGCTCGTAA
TACGGGGACAATCGTTTCTGTGAGTGACGGAATTATCCGTATTCACGGTTTAAGTGAAGTGATGCAAGGGGAAATGATTG
CATTACCAGGCAATCGCTATGCGATGGCGCTTAACCTTGAGAGAGATTCTGTGGGTGCAGTAGTAATGGGACCTTATGCA
GATCTTGCTGAAGGAATGGAAGTTCAATGTACAGGTCGTATTCTTGAAGTCCCAGTTGGTCGTGGCTTACTAGGTCGTGT
CGTCAATACATTAGGTGAGCCAATCGATGGAAAAGGTGAGATCGAAAACGATGGTTTTTCACCAGTTGAAGTGATCGCAC
CAGGTGTTATCGATCGTAAATCGGTTGATCAACCAGTACAAACTGGTTATAAAGCGGTTGACTCCATGGTACCAATCGGT
CGTGGTCAGCGTGAATTAATTATCGGTGACCGTCAAACCGGTAAAACGGCATTAGCCATTGACGCCATCATCAATCAACG
TGATTCAGGTATCAAATGTATTTATGTTGCAATTGGTCAAAAAGCATCAACTATTGCTAACGTAGTACGTAAATTAGAAG
AACATAGTGCCTTACAAAATACAATCGTTGTTGTTGCATCAGCATCAGAATCTGCTGCTTTACAATATTTAGCACCATAT
TCTGGTTGTGCGATGGGTGAATATTTCCGTGATCGTGGTGAAGATGCATTAATCATTTATGATGATTTATCAAAACAAGC
CGTTGCGTATCGTCAAATTTCATTATTATTACGTCGCCCACCAGGTCGTGAAGCATTCCCAGGGGATGTTTTCTATTTAC
ACTCTCGTTTACTTGAGCGTGCTTCTCGCGTAAATGAAGAATATGTTGAGCGTTTCACGAATGGTGAAGTAAAAGGAAAA
ACGGGTTCTTTAACCGCACTTCCAATTATTGAAACTCAAGCAGGTGACGTTTCTGCGTTCGTTCCAACTAACGTGATTTC
GATTACTGATGGTCAGATTTTCTTAGAATCTAATTTATTTAACTCAGGTATTCGCCCTGCGGTAAACCCAGGTATTTCGG
TATCTCGTGTAGGTGGTTCAGCGCAAACTAAAGTAATTAAAAAATTAGCAGGTGGTATTCGTACTGCACTTGCACAATAT
CGTGAATTAGCGGCATTTGCTCAGTTCGCTTCGGATCTTGATGATGCAACACGTAAGCAATTATCACATGGTCAAAAAGT
AACTGAATTATTGAAACAAAAACAATACTCTCCGTTATCTGTAGCACAACAAGCATTAGTGTTATTTGCAGTAGAGTTTG
GTTACTTAGAAGAAGTGGACTTAGATCGTATTGGTTCATTTGAATCAGCACTTTTAGAGTATGCTAACCATAACTATGCT
GATTTTATGCGTGAGTTAACCCAATCTGGCAATTACAATGATGAAATTAAAGAGTCATTAAAAGGCATTTTGGATAGCTT
CAAAGCAAACAGTGCGTGGTAA

Upstream 100 bases:

>100_bases
AGGTGTAATTATTCGTACAGATGATTTTGTTATCGATGGAAGTAGTCGCGGACAACTGTCTCGTCTAGCAAATGAGCTGC
AATTATAAGAGGAATAAAAA

Downstream 100 bases:

>100_bases
GTTAACACTTTAAATGGAGAGACAAAATGGCAGGTGCTAAAGAGATAAGAACCAAAATCGCGAGTGTAAAAAGTACACAA
AAAATTACTAAAGCGATGGA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNSTEISELIKKRIAQFDVVSEARNTGTIVSVSDGIIRIHGLSEVMQGEMIALPGNRYAMALNLERDSVGAVVMGPYA
DLAEGMEVQCTGRILEVPVGRGLLGRVVNTLGEPIDGKGEIENDGFSPVEVIAPGVIDRKSVDQPVQTGYKAVDSMVPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTIANVVRKLEEHSALQNTIVVVASASESAALQYLAPY
SGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERASRVNEEYVERFTNGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNSGIRPAVNPGISVSRVGGSAQTKVIKKLAGGIRTALAQY
RELAAFAQFASDLDDATRKQLSHGQKVTELLKQKQYSPLSVAQQALVLFAVEFGYLEEVDLDRIGSFESALLEYANHNYA
DFMRELTQSGNYNDEIKESLKGILDSFKANSAW

Sequences:

>Translated_513_residues
MQLNSTEISELIKKRIAQFDVVSEARNTGTIVSVSDGIIRIHGLSEVMQGEMIALPGNRYAMALNLERDSVGAVVMGPYA
DLAEGMEVQCTGRILEVPVGRGLLGRVVNTLGEPIDGKGEIENDGFSPVEVIAPGVIDRKSVDQPVQTGYKAVDSMVPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTIANVVRKLEEHSALQNTIVVVASASESAALQYLAPY
SGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERASRVNEEYVERFTNGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNSGIRPAVNPGISVSRVGGSAQTKVIKKLAGGIRTALAQY
RELAAFAQFASDLDDATRKQLSHGQKVTELLKQKQYSPLSVAQQALVLFAVEFGYLEEVDLDRIGSFESALLEYANHNYA
DFMRELTQSGNYNDEIKESLKGILDSFKANSAW
>Mature_513_residues
MQLNSTEISELIKKRIAQFDVVSEARNTGTIVSVSDGIIRIHGLSEVMQGEMIALPGNRYAMALNLERDSVGAVVMGPYA
DLAEGMEVQCTGRILEVPVGRGLLGRVVNTLGEPIDGKGEIENDGFSPVEVIAPGVIDRKSVDQPVQTGYKAVDSMVPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTIANVVRKLEEHSALQNTIVVVASASESAALQYLAPY
SGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERASRVNEEYVERFTNGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNSGIRPAVNPGISVSRVGGSAQTKVIKKLAGGIRTALAQY
RELAAFAQFASDLDDATRKQLSHGQKVTELLKQKQYSPLSVAQQALVLFAVEFGYLEEVDLDRIGSFESALLEYANHNYA
DFMRELTQSGNYNDEIKESLKGILDSFKANSAW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=513, Percent_Identity=55.3606237816764, Blast_Score=551, Evalue=1e-157,
Organism=Homo sapiens, GI4757810, Length=513, Percent_Identity=55.3606237816764, Blast_Score=551, Evalue=1e-157,
Organism=Homo sapiens, GI19913428, Length=315, Percent_Identity=27.6190476190476, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI32189394, Length=436, Percent_Identity=25.2293577981651, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI19913426, Length=313, Percent_Identity=26.8370607028754, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI19913424, Length=263, Percent_Identity=27.7566539923954, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=86.5497076023392, Blast_Score=922, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=382, Percent_Identity=25.9162303664921, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788251, Length=366, Percent_Identity=24.0437158469945, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=54.7572815533981, Blast_Score=546, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=54.7572815533981, Blast_Score=546, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI71988074, Length=515, Percent_Identity=51.2621359223301, Blast_Score=501, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17510931, Length=368, Percent_Identity=25.8152173913043, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=370, Percent_Identity=26.4864864864865, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=440, Percent_Identity=24.5454545454545, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17509265, Length=47, Percent_Identity=68.0851063829787, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=262, Percent_Identity=26.7175572519084, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=513, Percent_Identity=53.9961013645224, Blast_Score=558, Evalue=1e-159,
Organism=Saccharomyces cerevisiae, GI6322581, Length=461, Percent_Identity=24.295010845987, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319603, Length=369, Percent_Identity=26.0162601626016, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24658560, Length=511, Percent_Identity=54.4031311154599, Blast_Score=538, Evalue=1e-153,
Organism=Drosophila melanogaster, GI281361666, Length=313, Percent_Identity=27.7955271565495, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24646341, Length=313, Percent_Identity=27.7955271565495, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136796, Length=313, Percent_Identity=27.7955271565495, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24638766, Length=397, Percent_Identity=25.6926952141058, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28574560, Length=323, Percent_Identity=26.9349845201238, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24583992, Length=340, Percent_Identity=25.8823529411765, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583988, Length=263, Percent_Identity=28.1368821292776, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583986, Length=263, Percent_Identity=28.1368821292776, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583984, Length=263, Percent_Identity=28.1368821292776, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20129479, Length=258, Percent_Identity=26.7441860465116, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55771; Mature: 55771

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNSTEISELIKKRIAQFDVVSEARNTGTIVSVSDGIIRIHGLSEVMQGEMIALPGNRY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEECHHHHHCCCEEEECCCCE
AMALNLERDSVGAVVMGPYADLAEGMEVQCTGRILEVPVGRGLLGRVVNTLGEPIDGKGE
EEEEEECCCCCCEEEECCHHHHHCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCC
IENDGFSPVEVIAPGVIDRKSVDQPVQTGYKAVDSMVPIGRGQRELIIGDRQTGKTALAI
CCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQRDSGIKCIYVAIGQKASTIANVVRKLEEHSALQNTIVVVASASESAALQYLAPY
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHCCC
SGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLER
CCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASRVNEEYVERFTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLF
HHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCC
NSGIRPAVNPGISVSRVGGSAQTKVIKKLAGGIRTALAQYRELAAFAQFASDLDDATRKQ
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHGQKVTELLKQKQYSPLSVAQQALVLFAVEFGYLEEVDLDRIGSFESALLEYANHNYA
HHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHCCCHH
DFMRELTQSGNYNDEIKESLKGILDSFKANSAW
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQLNSTEISELIKKRIAQFDVVSEARNTGTIVSVSDGIIRIHGLSEVMQGEMIALPGNRY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEECHHHHHCCCEEEECCCCE
AMALNLERDSVGAVVMGPYADLAEGMEVQCTGRILEVPVGRGLLGRVVNTLGEPIDGKGE
EEEEEECCCCCCEEEECCHHHHHCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCC
IENDGFSPVEVIAPGVIDRKSVDQPVQTGYKAVDSMVPIGRGQRELIIGDRQTGKTALAI
CCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQRDSGIKCIYVAIGQKASTIANVVRKLEEHSALQNTIVVVASASESAALQYLAPY
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHCCC
SGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLER
CCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASRVNEEYVERFTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLF
HHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCC
NSGIRPAVNPGISVSRVGGSAQTKVIKKLAGGIRTALAQYRELAAFAQFASDLDDATRKQ
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHGQKVTELLKQKQYSPLSVAQQALVLFAVEFGYLEEVDLDRIGSFESALLEYANHNYA
HHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHCCCHH
DFMRELTQSGNYNDEIKESLKGILDSFKANSAW
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA