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The map label for this gene is blh [H]

Identifier: 15603344

GI number: 15603344

Start: 1673023

End: 1673955

Strand: Direct

Name: blh [H]

Synonym: PM1479

Alternate gene names: 15603344

Gene position: 1673023-1673955 (Clockwise)

Preceding gene: 15603343

Following gene: 15603345

Centisome position: 74.11

GC content: 38.16

Gene sequence:

>933_bases
TTGTCAAACCAAGAAGTTGTGCTTGTCAAAAAAATTAACTTAATGGAAAGTATCATGAAAATTGCGATACCTGAAATCAA
AGCATTTTTTGATGAACCAACGAATACATACAGTTATGTTGTTCACGATCCTGATACGCAAGCTTGTGCTATTATTGATT
CTGTTTTGGATTTAGATTATACGGCAGGAAAAATCAGCACCTTATCTGCAGATGCCATTATTGCGTATATTCAACAACAG
CAATTGACTGTTGAGTGGATTTTAGAAACGCATGTGCATGCCGATCATTTATCCGCTGCGCCTTATTTACAAGAAAAATT
AGGTGGAAAAACAGGTATTGGTCAACATATCACAACTGTACAAAATGTATTTGGTAAGGCATTTAATGCCGGTACGGAAT
TTGCCCGTGATGGTAGTCAATTTAATCGCTTGTTTCATGATGGAGATGAATTCACTCTCGGCCGCCTTCCTGTTAAAGTC
ATTCATACCCCTGGACATACTCCAGCTTGTGTCAGTTATTTAATTGGAGATGCCGTTTTCGTAGGGGATACTTTATTCAT
GCCAGATTATGGGACTGCACGTTGTGATTTTCCTGGCGGGGATGCCAATGTGTTATATCAATCTGTACAAAAATTACTTG
CTTTACCTGAAGAAACACGGATGTTCTTATGCCACGATTATTTACCTAAACATCGTCAAGAATATTGCTATGAAACCACT
GTTAAAGCACAGAAAGAACAAAATATTCATATCCACCACGGGGTTAAGCAAGCAGAATTTGTTCAAATGCGCCAATCGCG
TGATGCGACATTATCTATGCCGAAATTGATCATTCCTTCGGTACAAGTCAATATGCGAGCAGGACATTTACCGCCAGCAG
AAGAAAATGGGCAAGTCTATTTAAAAGTGCCGATTAATTTATTTAAATCATAA

Upstream 100 bases:

>100_bases
ATTAGCGACATAGGCGGACCAATCGATCTGATTCTTGTGGTTTTAGCCTATTTTGGTGGTTTCTTAGCAAGCACAATGCT
ACTTTATAGTATTATAGGCT

Downstream 100 bases:

>100_bases
TTTACAGGGGAAAGCGCTATGACAATTCAAACCATCTGTGTCAATGATGTATGTGAAAAACTGAAGCAAGGGGCAATTTT
AGTTGATATTCGTCAACCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSNQEVVLVKKINLMESIMKIAIPEIKAFFDEPTNTYSYVVHDPDTQACAIIDSVLDLDYTAGKISTLSADAIIAYIQQQ
QLTVEWILETHVHADHLSAAPYLQEKLGGKTGIGQHITTVQNVFGKAFNAGTEFARDGSQFNRLFHDGDEFTLGRLPVKV
IHTPGHTPACVSYLIGDAVFVGDTLFMPDYGTARCDFPGGDANVLYQSVQKLLALPEETRMFLCHDYLPKHRQEYCYETT
VKAQKEQNIHIHHGVKQAEFVQMRQSRDATLSMPKLIIPSVQVNMRAGHLPPAEENGQVYLKVPINLFKS

Sequences:

>Translated_310_residues
MSNQEVVLVKKINLMESIMKIAIPEIKAFFDEPTNTYSYVVHDPDTQACAIIDSVLDLDYTAGKISTLSADAIIAYIQQQ
QLTVEWILETHVHADHLSAAPYLQEKLGGKTGIGQHITTVQNVFGKAFNAGTEFARDGSQFNRLFHDGDEFTLGRLPVKV
IHTPGHTPACVSYLIGDAVFVGDTLFMPDYGTARCDFPGGDANVLYQSVQKLLALPEETRMFLCHDYLPKHRQEYCYETT
VKAQKEQNIHIHHGVKQAEFVQMRQSRDATLSMPKLIIPSVQVNMRAGHLPPAEENGQVYLKVPINLFKS
>Mature_309_residues
SNQEVVLVKKINLMESIMKIAIPEIKAFFDEPTNTYSYVVHDPDTQACAIIDSVLDLDYTAGKISTLSADAIIAYIQQQQ
LTVEWILETHVHADHLSAAPYLQEKLGGKTGIGQHITTVQNVFGKAFNAGTEFARDGSQFNRLFHDGDEFTLGRLPVKVI
HTPGHTPACVSYLIGDAVFVGDTLFMPDYGTARCDFPGGDANVLYQSVQKLLALPEETRMFLCHDYLPKHRQEYCYETTV
KAQKEQNIHIHHGVKQAEFVQMRQSRDATLSMPKLIIPSVQVNMRAGHLPPAEENGQVYLKVPINLFKS

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=267, Percent_Identity=27.3408239700375, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17538952, Length=268, Percent_Identity=27.2388059701493, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221330176, Length=299, Percent_Identity=27.7591973244147, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667703, Length=201, Percent_Identity=29.3532338308458, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356335, Length=201, Percent_Identity=29.3532338308458, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24667711, Length=201, Percent_Identity=29.3532338308458, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 34660; Mature: 34529

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQEVVLVKKINLMESIMKIAIPEIKAFFDEPTNTYSYVVHDPDTQACAIIDSVLDLDY
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCC
TAGKISTLSADAIIAYIQQQQLTVEWILETHVHADHLSAAPYLQEKLGGKTGIGQHITTV
CCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCCCCCCCHHHHHH
QNVFGKAFNAGTEFARDGSQFNRLFHDGDEFTLGRLPVKVIHTPGHTPACVSYLIGDAVF
HHHHHHHHCCCHHHHHCHHHHHHHHCCCCCEEECCCCEEEEECCCCCHHHHHHHHHCHHE
VGDTLFMPDYGTARCDFPGGDANVLYQSVQKLLALPEETRMFLCHDYLPKHRQEYCYETT
ECCEEECCCCCCEECCCCCCCHHHHHHHHHHHHCCCCHHHEEHHHHHCHHHHHHHHHHHH
VKAQKEQNIHIHHGVKQAEFVQMRQSRDATLSMPKLIIPSVQVNMRAGHLPPAEENGQVY
HHHHHCCCEEEECCCCHHHHHHHHHCCCCCCCCCCEECCCEEEEEECCCCCCCCCCCEEE
LKVPINLFKS
EEECCHHHCC
>Mature Secondary Structure 
SNQEVVLVKKINLMESIMKIAIPEIKAFFDEPTNTYSYVVHDPDTQACAIIDSVLDLDY
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCC
TAGKISTLSADAIIAYIQQQQLTVEWILETHVHADHLSAAPYLQEKLGGKTGIGQHITTV
CCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCCCCCCCHHHHHH
QNVFGKAFNAGTEFARDGSQFNRLFHDGDEFTLGRLPVKVIHTPGHTPACVSYLIGDAVF
HHHHHHHHCCCHHHHHCHHHHHHHHCCCCCEEECCCCEEEEECCCCCHHHHHHHHHCHHE
VGDTLFMPDYGTARCDFPGGDANVLYQSVQKLLALPEETRMFLCHDYLPKHRQEYCYETT
ECCEEECCCCCCEECCCCCCCHHHHHHHHHHHHCCCCHHHEEHHHHHCHHHHHHHHHHHH
VKAQKEQNIHIHHGVKQAEFVQMRQSRDATLSMPKLIIPSVQVNMRAGHLPPAEENGQVY
HHHHHCCCEEEECCCCHHHHHHHHHCCCCCCCCCCEECCCEEEEEECCCCCCCCCCCEEE
LKVPINLFKS
EEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]