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The map label for this gene is pabB [C]

Identifier: 15603329

GI number: 15603329

Start: 1655767

End: 1656741

Strand: Direct

Name: pabB [C]

Synonym: PM1464

Alternate gene names: 15603329

Gene position: 1655767-1656741 (Clockwise)

Preceding gene: 15603327

Following gene: 15603330

Centisome position: 73.35

GC content: 44.51

Gene sequence:

>975_bases
ATGTCCTTGCATGCTTTTATTCAACAGGCGAACCAGTTTGGTGAACAACGCCAGCCGTTTTTCTTTTTGATTGATTTTGA
ACAACAGCAACCGATTATTTGTCCGTTAGCTCAGGCGGCAGAATTAGGGTTATTTTTTGCGATACGAGGGCAGCAGAATG
TCAATTGGCAGACTGAAATGCCTCACAAGCCTTTTGAACTGCACAAATTTCCTATCTCAAAAGCAGCTTATCAGCGTGGC
TTTGACTTAGTGCAAAAAGAGCTACAAAAAGGCAATTCTTATTTGTTGAATCTCACCTATCCGACCGAAATTAACACGAA
TTGGCGTCTGGAACAGGTTTTTCAACAAACGACAGCCCCCTATAAATTGTACTATCGGGATCGCTTTGTGTGCTTTTCGC
CTGAATGCTTTGTCAATATTCATCACAATCAAATTTATACTTACCCGATGAAAGGCACCATTGATGCTACGCTGCCTGAG
GCGGAAAAACGCTTGTTAGATTCTGACAAAGAGCGGCAAGAACATTACACCATTGTGGATTTAATGCGCAACGATTTGGC
AACAGTCGCCGAGAAGGTGGAAGTGACGCGCTTTCGTTATGTGGAAAAGATTCAGACACAAAAAGGGGCAATCTTGCAGA
CAAGTTCGGAAATTCGCGGCGATCTTGCGGAAAATTGGCAAGCCCGCATTGGCACGATATTAGCCACGTTGTTGCCTGCA
GGCTCGATTAGTGGGGCACCGAAAGAAAAAACCGTGCAAATTATTCACGCCGCAGAACAGCGGCCACGCGGTTATTACAC
GGGGATTTTTGGTCTGTTCGATGGTGAGTCGTTACAAAGTGCGGTGGCAATTCGTTTTATTGAGCAAGTGGACGAAAAAT
TGATTTTCCGCAGCGGTGGTGGGATTACGATCTTAAGCGAGCTAGAAGACGAGTACCAAGAATTGATCCAAAAAGTGTAT
GTACCAGTAGGATAA

Upstream 100 bases:

>100_bases
CCATATTCTGTGGAGAAAGAGGCAAAGTATAAAGGAAAATGCGGATTTTTGGTTTATTTTCCGTTAAACTTTCACTTATT
TTTTCAAATGTAGATAACTT

Downstream 100 bases:

>100_bases
GCGATGACATTTCCTTTATTTGAGACGATCGCCATTGTGAACGGTGAAATTCAGCACCTTGCCTTGCATCAACAACGTTA
TGCGGCAAGTTTGGCGACCT

Product: para-aminobenzoate synthase component I

Products: 4-amino-4-deoxychorismate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSLHAFIQQANQFGEQRQPFFFLIDFEQQQPIICPLAQAAELGLFFAIRGQQNVNWQTEMPHKPFELHKFPISKAAYQRG
FDLVQKELQKGNSYLLNLTYPTEINTNWRLEQVFQQTTAPYKLYYRDRFVCFSPECFVNIHHNQIYTYPMKGTIDATLPE
AEKRLLDSDKERQEHYTIVDLMRNDLATVAEKVEVTRFRYVEKIQTQKGAILQTSSEIRGDLAENWQARIGTILATLLPA
GSISGAPKEKTVQIIHAAEQRPRGYYTGIFGLFDGESLQSAVAIRFIEQVDEKLIFRSGGGITILSELEDEYQELIQKVY
VPVG

Sequences:

>Translated_324_residues
MSLHAFIQQANQFGEQRQPFFFLIDFEQQQPIICPLAQAAELGLFFAIRGQQNVNWQTEMPHKPFELHKFPISKAAYQRG
FDLVQKELQKGNSYLLNLTYPTEINTNWRLEQVFQQTTAPYKLYYRDRFVCFSPECFVNIHHNQIYTYPMKGTIDATLPE
AEKRLLDSDKERQEHYTIVDLMRNDLATVAEKVEVTRFRYVEKIQTQKGAILQTSSEIRGDLAENWQARIGTILATLLPA
GSISGAPKEKTVQIIHAAEQRPRGYYTGIFGLFDGESLQSAVAIRFIEQVDEKLIFRSGGGITILSELEDEYQELIQKVY
VPVG
>Mature_323_residues
SLHAFIQQANQFGEQRQPFFFLIDFEQQQPIICPLAQAAELGLFFAIRGQQNVNWQTEMPHKPFELHKFPISKAAYQRGF
DLVQKELQKGNSYLLNLTYPTEINTNWRLEQVFQQTTAPYKLYYRDRFVCFSPECFVNIHHNQIYTYPMKGTIDATLPEA
EKRLLDSDKERQEHYTIVDLMRNDLATVAEKVEVTRFRYVEKIQTQKGAILQTSSEIRGDLAENWQARIGTILATLLPAG
SISGAPKEKTVQIIHAAEQRPRGYYTGIFGLFDGESLQSAVAIRFIEQVDEKLIFRSGGGITILSELEDEYQELIQKVYV
PVG

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To the C-terminal of para-aminobenzoate synthase component I

Homologues:

Organism=Escherichia coli, GI1788114, Length=281, Percent_Identity=30.2491103202847, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787518, Length=272, Percent_Identity=28.3088235294118, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324361, Length=309, Percent_Identity=27.831715210356, Blast_Score=89, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6320935, Length=266, Percent_Identity=26.6917293233083, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1464_PASMU (Q9CKY6)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246403.1
- ProteinModelPortal:   Q9CKY6
- SMR:   Q9CKY6
- GeneID:   1244811
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1464
- NMPDR:   fig|272843.1.peg.1465
- HOGENOM:   HBG296599
- OMA:   YPMKGTI
- ProtClustDB:   PRK07093
- BioCyc:   PMUL272843:PM1464-MONOMER
- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR015890
- Gene3D:   G3DSA:3.60.120.10
- PANTHER:   PTHR11236
- PRINTS:   PR00095

Pfam domain/function: PF00425 Chorismate_bind; SSF56322 TRPE_1_chor_bd

EC number: 6.3.5.8

Molecular weight: Translated: 37310; Mature: 37179

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLHAFIQQANQFGEQRQPFFFLIDFEQQQPIICPLAQAAELGLFFAIRGQQNVNWQTEM
CCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHCCCEEEEEECCCCCCCCCCC
PHKPFELHKFPISKAAYQRGFDLVQKELQKGNSYLLNLTYPTEINTNWRLEQVFQQTTAP
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHCCCC
YKLYYRDRFVCFSPECFVNIHHNQIYTYPMKGTIDATLPEAEKRLLDSDKERQEHYTIVD
EEEEEECEEEEECCCEEEEEECCEEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHH
LMRNDLATVAEKVEVTRFRYVEKIQTQKGAILQTSSEIRGDLAENWQARIGTILATLLPA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHCHHHHHHHHHHHHHHHHHHCC
GSISGAPKEKTVQIIHAAEQRPRGYYTGIFGLFDGESLQSAVAIRFIEQVDEKLIFRSGG
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHEEECCC
GITILSELEDEYQELIQKVYVPVG
CEEEHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLHAFIQQANQFGEQRQPFFFLIDFEQQQPIICPLAQAAELGLFFAIRGQQNVNWQTEM
CHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHCCCEEEEEECCCCCCCCCCC
PHKPFELHKFPISKAAYQRGFDLVQKELQKGNSYLLNLTYPTEINTNWRLEQVFQQTTAP
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHCCCC
YKLYYRDRFVCFSPECFVNIHHNQIYTYPMKGTIDATLPEAEKRLLDSDKERQEHYTIVD
EEEEEECEEEEECCCEEEEEECCEEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHH
LMRNDLATVAEKVEVTRFRYVEKIQTQKGAILQTSSEIRGDLAENWQARIGTILATLLPA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHCHHHHHHHHHHHHHHHHHHCC
GSISGAPKEKTVQIIHAAEQRPRGYYTGIFGLFDGESLQSAVAIRFIEQVDEKLIFRSGG
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHEEECCC
GITILSELEDEYQELIQKVYVPVG
CEEEHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: chorismate; L-glutamine

Specific reaction: chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate

General reaction: Lyases; Carbon-Carbon Lyases; Oxo-Acid-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100