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The map label for this gene is pgtA [H]

Identifier: 15603325

GI number: 15603325

Start: 1651718

End: 1652971

Strand: Direct

Name: pgtA [H]

Synonym: PM1460

Alternate gene names: 15603325

Gene position: 1651718-1652971 (Clockwise)

Preceding gene: 15603324

Following gene: 15603326

Centisome position: 73.17

GC content: 39.39

Gene sequence:

>1254_bases
ATGTTTAATCCTGCCTATAACGTACTCTTAATTGATGACGACATGGATATTCTCGATTCTTATCAGGATTTATTACGACA
AGAAGGCTATCAAGTGATCACCTGTGCAGACCCGATAGATATTGTGGCGCAAATTCCAGAAAACTGGATTGGGGTCATCC
TTTGTGATGTCTTGTTGCCCAATATTTCAGGTTTAAAAATCTTAGAAGATATCATTCAACGCGATGCACAGATTCCTGTG
ATTATGATCACGGGTCACGGTGATGTTCCCATGGCAGTGGATGCAGTCAAAAAAGGCGCCACAAATTTTCTTGAAAAACC
CATCTCAGCAGAAAATTTACTGATTCAAGTCGCACAAGCATTAGAAAAACGCGCTGCCTTAATGGAAAATCGCCAATGGC
AATTAGAAAAGCTGAGCGAAAGTTTTATTGGTCAAAGTGAATGGATTATCGCTATGCGCCACCAGCTACAAAAACTCGCC
GACATTGATGTCCCCCTCTTTTTATGGGGAGAAACAGGCACCGGACGTTATCTTTCTGCCACTTACTTACATAAACTCAG
TGCTCGTCAGAACGCTCCGTTTATTTATCATGAATGTTTACCGCAAGCACAATGCAACCTAGACAAATGCCTAGACGATG
TACAGCAGGGCACACTGGTGTTAAAAAATATCCACCATTTAGCACAAACGGAACAGCAACATTTAGCCAAAGCCTTAAAT
ATGGAAGGATGCGCCTTTAGGCTGATCTTAATCAGTGATTTTGCACTGCTCACGCTCATTCAAGAACAACGGATTTGCTC
AGAACTGTATTATTTATTTTTACATACGCAATTTGAATTATTGCCACTCAAAAAACGCCCCAGCGATATTCTGCCTATCT
TCTGCCATTATGTACATAAAAGTTGCGCCAGATTAAATAAAGAGTACGTCGAACCCAATAAAAAATTAATACAACATTTA
CTCACACAAACTTGGCAAGGCAATGTCAAAGAGCTTATCCATGTGGCAGAATTATATGCGATTGGCTTATTGGCAGAACA
AACGCCAATGAGCAATCCCCTTGCCCTTAAAACAGAGCATATCAAACCGCTTGATGAACAGATCAATGAATATGAAAAAC
AAATCATTGAAGATGCGTTAATTTTTTATCAAGGGCGAATTAATGATGTGGCGACTTATCTGAATATTCCACGTAAAAAA
CTCTATTTGCGTATGAAAAAACACCATATCGATAAAAAGCACTATAAATGTTAG

Upstream 100 bases:

>100_bases
ATTAGTCAATCCATCATGGAGCAATGTCAAGGATCATTGACCATTGCCTCTACTCTCACCCATAATGCATTAGTGATATT
AAAATTTAAGGTGGCTCAAC

Downstream 100 bases:

>100_bases
GCAAAAAACTAAGAAAATAGGATGTGATGCCTGCGCTCAATGTGGGCTATTCTTTGTTCGCGTCCTGCATAAATATAAAT
CCTGCTTCTTATCACAATCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MFNPAYNVLLIDDDMDILDSYQDLLRQEGYQVITCADPIDIVAQIPENWIGVILCDVLLPNISGLKILEDIIQRDAQIPV
IMITGHGDVPMAVDAVKKGATNFLEKPISAENLLIQVAQALEKRAALMENRQWQLEKLSESFIGQSEWIIAMRHQLQKLA
DIDVPLFLWGETGTGRYLSATYLHKLSARQNAPFIYHECLPQAQCNLDKCLDDVQQGTLVLKNIHHLAQTEQQHLAKALN
MEGCAFRLILISDFALLTLIQEQRICSELYYLFLHTQFELLPLKKRPSDILPIFCHYVHKSCARLNKEYVEPNKKLIQHL
LTQTWQGNVKELIHVAELYAIGLLAEQTPMSNPLALKTEHIKPLDEQINEYEKQIIEDALIFYQGRINDVATYLNIPRKK
LYLRMKKHHIDKKHYKC

Sequences:

>Translated_417_residues
MFNPAYNVLLIDDDMDILDSYQDLLRQEGYQVITCADPIDIVAQIPENWIGVILCDVLLPNISGLKILEDIIQRDAQIPV
IMITGHGDVPMAVDAVKKGATNFLEKPISAENLLIQVAQALEKRAALMENRQWQLEKLSESFIGQSEWIIAMRHQLQKLA
DIDVPLFLWGETGTGRYLSATYLHKLSARQNAPFIYHECLPQAQCNLDKCLDDVQQGTLVLKNIHHLAQTEQQHLAKALN
MEGCAFRLILISDFALLTLIQEQRICSELYYLFLHTQFELLPLKKRPSDILPIFCHYVHKSCARLNKEYVEPNKKLIQHL
LTQTWQGNVKELIHVAELYAIGLLAEQTPMSNPLALKTEHIKPLDEQINEYEKQIIEDALIFYQGRINDVATYLNIPRKK
LYLRMKKHHIDKKHYKC
>Mature_417_residues
MFNPAYNVLLIDDDMDILDSYQDLLRQEGYQVITCADPIDIVAQIPENWIGVILCDVLLPNISGLKILEDIIQRDAQIPV
IMITGHGDVPMAVDAVKKGATNFLEKPISAENLLIQVAQALEKRAALMENRQWQLEKLSESFIGQSEWIIAMRHQLQKLA
DIDVPLFLWGETGTGRYLSATYLHKLSARQNAPFIYHECLPQAQCNLDKCLDDVQQGTLVLKNIHHLAQTEQQHLAKALN
MEGCAFRLILISDFALLTLIQEQRICSELYYLFLHTQFELLPLKKRPSDILPIFCHYVHKSCARLNKEYVEPNKKLIQHL
LTQTWQGNVKELIHVAELYAIGLLAEQTPMSNPLALKTEHIKPLDEQINEYEKQIIEDALIFYQGRINDVATYLNIPRKK
LYLRMKKHHIDKKHYKC

Specific function: Member of the two-component regulatory system pgtB/pgtA that regulates the inducible phosphoglycerate transport system. When activated by pgtB it acts in conjunction with sigma-54 as a transcriptional activator [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=449, Percent_Identity=24.2761692650334, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1790437, Length=443, Percent_Identity=25.9593679458239, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788550, Length=456, Percent_Identity=23.6842105263158, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790299, Length=461, Percent_Identity=24.0780911062907, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789087, Length=320, Percent_Identity=24.375, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786524, Length=310, Percent_Identity=24.1935483870968, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787583, Length=234, Percent_Identity=27.3504273504274, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786599, Length=139, Percent_Identity=26.6187050359712, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 48008; Mature: 48008

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNPAYNVLLIDDDMDILDSYQDLLRQEGYQVITCADPIDIVAQIPENWIGVILCDVLLP
CCCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCHHHHHHHHHHHHC
NISGLKILEDIIQRDAQIPVIMITGHGDVPMAVDAVKKGATNFLEKPISAENLLIQVAQA
CCCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LEKRAALMENRQWQLEKLSESFIGQSEWIIAMRHQLQKLADIDVPLFLWGETGTGRYLSA
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHH
TYLHKLSARQNAPFIYHECLPQAQCNLDKCLDDVQQGTLVLKNIHHLAQTEQQHLAKALN
HHHHHHHHCCCCCCHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MEGCAFRLILISDFALLTLIQEQRICSELYYLFLHTQFELLPLKKRPSDILPIFCHYVHK
CCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHHHHHHHHH
SCARLNKEYVEPNKKLIQHLLTQTWQGNVKELIHVAELYAIGLLAEQTPMSNPLALKTEH
HHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHH
IKPLDEQINEYEKQIIEDALIFYQGRINDVATYLNIPRKKLYLRMKKHHIDKKHYKC
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MFNPAYNVLLIDDDMDILDSYQDLLRQEGYQVITCADPIDIVAQIPENWIGVILCDVLLP
CCCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCHHHHHHHHHHHHC
NISGLKILEDIIQRDAQIPVIMITGHGDVPMAVDAVKKGATNFLEKPISAENLLIQVAQA
CCCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LEKRAALMENRQWQLEKLSESFIGQSEWIIAMRHQLQKLADIDVPLFLWGETGTGRYLSA
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHH
TYLHKLSARQNAPFIYHECLPQAQCNLDKCLDDVQQGTLVLKNIHHLAQTEQQHLAKALN
HHHHHHHHCCCCCCHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MEGCAFRLILISDFALLTLIQEQRICSELYYLFLHTQFELLPLKKRPSDILPIFCHYVHK
CCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHHHHHHHHH
SCARLNKEYVEPNKKLIQHLLTQTWQGNVKELIHVAELYAIGLLAEQTPMSNPLALKTEH
HHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHH
IKPLDEQINEYEKQIIEDALIFYQGRINDVATYLNIPRKKLYLRMKKHHIDKKHYKC
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3023201; 11677609; 2842311 [H]