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The map label for this gene is dcuB [H]

Identifier: 15603299

GI number: 15603299

Start: 1619509

End: 1620822

Strand: Direct

Name: dcuB [H]

Synonym: PM1434

Alternate gene names: 15603299

Gene position: 1619509-1620822 (Clockwise)

Preceding gene: 15603292

Following gene: 15603301

Centisome position: 71.74

GC content: 44.06

Gene sequence:

>1314_bases
ATGTTCTTCATTCAATTTGGCATAGTTTTACTATGTATTTTAGTCGGGGCACGTATTGGCGGTATCGGGCTCGGAGTTAT
GGGGGGCTTAGGACTTGCTATTCTCTCCTTTGGGTTTGGTTTAAAACCAGCCGGCTTACCTATCGACGTTATGTTTATGA
TCATGGCAGTCGTCTCTGCCGCCGCAGCGATGCAAGCGTCAGGCGGTTTAGATTATATGATCAAAATTGCGGCGCGTATT
TTACGTAAAAATCCTAAATACATTACTTTTATGGCACCTGCTGTCACTTGGACTTTCACCGTATTAGCGGGTACCGGGCA
CGTGGCTTATTCTGTACTACCGGTTATCGCGGAAGTCAGTCGCCATAATGGCGTACGCCCAGAACGCCCACTGTCTATGG
CTGTGATTGCTTCACAATTCGCCATTGTGGCTAGTCCTATCGCGGCAGCCGTGGTTGCTGTAGTGAACTTTCTCGAGCCA
CAGGGCATCACCTTAGGGAATGTCTTATCTGTCACCATTCCAGCCACGGTATTAGGACTTTTTGTGGCGTGTTTATTTGT
TAATAAAATGGGGAAAGAATTACATGAAGACCCTGTTTATTTAGCCAAATTACAAGATCCAGAATACGTTAAAGAAAGCC
AAGCACAATCTACCATTGGTGAAGCTGACATCTCAGATAAAGCAAAAGTATCTGTAGGTATCTTCTTGTTTGCTGCATTA
TTAGTAGTATTAATGGGGACGTTCCCAAGCTTACGCCCAACCTTTGATGGCAAAGCAATGGGGATGGCACACACCATTGA
AATCGTGATGCTTTCTGCAGGTGCACTCATTATGTTATTGTGTAAACCTGATGGCACAGCGGTAACTAAAGGATCGGTCT
TCCATGCAGGTATGCGTGCTGTCATTGCGATTTTCGGTATCGCATGGCTAGGTGATACGCTTATGCAAGCCCATATTGTG
GAAGTCAAAGATTCAGTAAAATACCTCGTTGAAACGGCACCATGGGCGTTTGCATTTGCACTCTTTGCCTTATCTGTATT
AGTGAATAGCCAAGGGGCAACAGTCGCCACCTTATTCCCACTTGGTATTGCATTAGGTATCCCAGCACCGATCTTGATTG
GTACCTTTGTGGCAGTAAACGGTTATTTCTTTATTCCAAACTACGGTCCAATCATTGCCTCTATTGATTTTGATACCACT
GGAACAACACGCATTGGTAAATTCATTTTCAACCACAGCTTTATGCTCCCTGGTCTATTAAGCATGGCATTTAGCTTAGG
TTTTGGTTTACTGTTTGCCAATTTTATTCTTTAA

Upstream 100 bases:

>100_bases
TATTTATTGCTATATTAATCCCGATTCTACGAAAGTAGGAAGGCAACGGATCATTTCTTTTCTGCAATCTTCATTCAAAC
TTATCACATAAGGATACATT

Downstream 100 bases:

>100_bases
GTAAACATTAGAAGACAAAAACGCGGTTTGATATTGAATCAAACCGCGTTTTTTGTCGATGACTTCAACACGTCTCGTAA
AACTTGCTTAAAAATGACCG

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MFFIQFGIVLLCILVGARIGGIGLGVMGGLGLAILSFGFGLKPAGLPIDVMFMIMAVVSAAAAMQASGGLDYMIKIAARI
LRKNPKYITFMAPAVTWTFTVLAGTGHVAYSVLPVIAEVSRHNGVRPERPLSMAVIASQFAIVASPIAAAVVAVVNFLEP
QGITLGNVLSVTIPATVLGLFVACLFVNKMGKELHEDPVYLAKLQDPEYVKESQAQSTIGEADISDKAKVSVGIFLFAAL
LVVLMGTFPSLRPTFDGKAMGMAHTIEIVMLSAGALIMLLCKPDGTAVTKGSVFHAGMRAVIAIFGIAWLGDTLMQAHIV
EVKDSVKYLVETAPWAFAFALFALSVLVNSQGATVATLFPLGIALGIPAPILIGTFVAVNGYFFIPNYGPIIASIDFDTT
GTTRIGKFIFNHSFMLPGLLSMAFSLGFGLLFANFIL

Sequences:

>Translated_437_residues
MFFIQFGIVLLCILVGARIGGIGLGVMGGLGLAILSFGFGLKPAGLPIDVMFMIMAVVSAAAAMQASGGLDYMIKIAARI
LRKNPKYITFMAPAVTWTFTVLAGTGHVAYSVLPVIAEVSRHNGVRPERPLSMAVIASQFAIVASPIAAAVVAVVNFLEP
QGITLGNVLSVTIPATVLGLFVACLFVNKMGKELHEDPVYLAKLQDPEYVKESQAQSTIGEADISDKAKVSVGIFLFAAL
LVVLMGTFPSLRPTFDGKAMGMAHTIEIVMLSAGALIMLLCKPDGTAVTKGSVFHAGMRAVIAIFGIAWLGDTLMQAHIV
EVKDSVKYLVETAPWAFAFALFALSVLVNSQGATVATLFPLGIALGIPAPILIGTFVAVNGYFFIPNYGPIIASIDFDTT
GTTRIGKFIFNHSFMLPGLLSMAFSLGFGLLFANFIL
>Mature_437_residues
MFFIQFGIVLLCILVGARIGGIGLGVMGGLGLAILSFGFGLKPAGLPIDVMFMIMAVVSAAAAMQASGGLDYMIKIAARI
LRKNPKYITFMAPAVTWTFTVLAGTGHVAYSVLPVIAEVSRHNGVRPERPLSMAVIASQFAIVASPIAAAVVAVVNFLEP
QGITLGNVLSVTIPATVLGLFVACLFVNKMGKELHEDPVYLAKLQDPEYVKESQAQSTIGEADISDKAKVSVGIFLFAAL
LVVLMGTFPSLRPTFDGKAMGMAHTIEIVMLSAGALIMLLCKPDGTAVTKGSVFHAGMRAVIAIFGIAWLGDTLMQAHIV
EVKDSVKYLVETAPWAFAFALFALSVLVNSQGATVATLFPLGIALGIPAPILIGTFVAVNGYFFIPNYGPIIASIDFDTT
GTTRIGKFIFNHSFMLPGLLSMAFSLGFGLLFANFIL

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790580, Length=441, Percent_Identity=41.9501133786848, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI1790565, Length=405, Percent_Identity=40, Blast_Score=301, Evalue=6e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 46102; Mature: 46102

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFIQFGIVLLCILVGARIGGIGLGVMGGLGLAILSFGFGLKPAGLPIDVMFMIMAVVSA
CEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AAAMQASGGLDYMIKIAARILRKNPKYITFMAPAVTWTFTVLAGTGHVAYSVLPVIAEVS
HHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECHHHEEEEEEECCCHHHHHHHHHHHHHH
RHNGVRPERPLSMAVIASQFAIVASPIAAAVVAVVNFLEPQGITLGNVLSVTIPATVLGL
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEHHHHHHHHH
FVACLFVNKMGKELHEDPVYLAKLQDPEYVKESQAQSTIGEADISDKAKVSVGIFLFAAL
HHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LVVLMGTFPSLRPTFDGKAMGMAHTIEIVMLSAGALIMLLCKPDGTAVTKGSVFHAGMRA
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHEECCEEEEEEECCCCCEEECCHHHHHHHHH
VIAIFGIAWLGDTLMQAHIVEVKDSVKYLVETAPWAFAFALFALSVLVNSQGATVATLFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEHHHH
LGIALGIPAPILIGTFVAVNGYFFIPNYGPIIASIDFDTTGTTRIGKFIFNHSFMLPGLL
HHHHHCCCHHHHHHHHHHHCCEEECCCCCCEEEEEECCCCCCHHHHHHHHCCCCHHHHHH
SMAFSLGFGLLFANFIL
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFFIQFGIVLLCILVGARIGGIGLGVMGGLGLAILSFGFGLKPAGLPIDVMFMIMAVVSA
CEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AAAMQASGGLDYMIKIAARILRKNPKYITFMAPAVTWTFTVLAGTGHVAYSVLPVIAEVS
HHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECHHHEEEEEEECCCHHHHHHHHHHHHHH
RHNGVRPERPLSMAVIASQFAIVASPIAAAVVAVVNFLEPQGITLGNVLSVTIPATVLGL
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEHHHHHHHHH
FVACLFVNKMGKELHEDPVYLAKLQDPEYVKESQAQSTIGEADISDKAKVSVGIFLFAAL
HHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LVVLMGTFPSLRPTFDGKAMGMAHTIEIVMLSAGALIMLLCKPDGTAVTKGSVFHAGMRA
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHEECCEEEEEEECCCCCEEECCHHHHHHHHH
VIAIFGIAWLGDTLMQAHIVEVKDSVKYLVETAPWAFAFALFALSVLVNSQGATVATLFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEHHHH
LGIALGIPAPILIGTFVAVNGYFFIPNYGPIIASIDFDTTGTTRIGKFIFNHSFMLPGLL
HHHHHCCCHHHHHHHHHHHCCEEECCCCCCEEEEEECCCCCCHHHHHHHHCCCCHHHHHH
SMAFSLGFGLLFANFIL
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]