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The map label for this gene is secY [H]

Identifier: 15603260

GI number: 15603260

Start: 1587990

End: 1589315

Strand: Reverse

Name: secY [H]

Synonym: PM1395

Alternate gene names: 15603260

Gene position: 1589315-1587990 (Counterclockwise)

Preceding gene: 15603261

Following gene: 15603259

Centisome position: 70.4

GC content: 39.59

Gene sequence:

>1326_bases
ATGGCTAAGCAACCAGGTTATCAAAGTAGAAGTACTCAAAGCGGTACAGGTGAACTTAAAAGCAGATTGTTATTTGTATT
AGGCGCACTTATTGTGTTCCGCATTGGTTCTTTCATTCCGGTTCCTGGTATTGATGCGGCCGTGTTAGCTCAATTAGTTG
AACAACAAAAAGGCACCATCATTGATATGTTTAACATGTTCTCTGGTGGTGCATTGAGTCGTGCGTCAATTTTTGCGTTA
GGTATTATGCCATATATCTCGGCATCGATTATCATCCAACTATTGACTACGGTTCATCCTGCACTTGCAGAATTAAAAAA
AGAGGGTGAGGCTGGTCGTCGTAAAATCAGCAAATACACGCGTTATTCAACGTTAGTCCTTGCGACATTACAGGCGGTTG
GTATTTCAACAGGCTTACCTAATATGCTACCTGGACTTGTCCCTAACGTAGGATTTAGTTTTTATCTTGCTGCAGTTATT
AGCTTGGTCACAGGAACAATGTTCTTAATGTGGTTAGGTGAGCAAATAACAGAACGTGGTATTGGTAATGGTATCTCTTT
AATTATTTTTGCGGGTATTGTTGCAGGGTTACCATCCGCGATTGGTCAAACGATTGAGCAAACTCGCCAAGGTCAAATGC
ATCTATTAGTTCTCTTATTGATCGCCGTTATTGTATTTGCTGTAACCTACTTTGTTGTCTTTGTTGAAAGAGGACAAAGA
AGAATTAAAGTTGAATATGCTAAGCGTCAGCAAGGTCGTCAGATTTTAGGTGGACACTCAACGCACTTACCATTAAAAGT
CAATATGGCAGGCGTTATTCCAGCAATTTTCGCATCAAGTATTATTTTATTCCCTGCGACATTAGCGCAGTGGCTTGGTG
AGGGATCGAGCTTAGAATGGTTAACAGATTTATCAATGTTATTGCATCCAGGTCAACCACTCTATTTGCTTGTTTATGCC
GTAGCGATCATCTTCTTTAGTTTTTTCTATACCGCAATGCAATATAATCCTCGTGATACAGCGGATAATTTGAAAAAATC
TGGTGCATTTATACCAGGAATTAGACCAGGTGAACAAACATCACGTTATATTGACAAAATTATGACTCGCTTAACCTTAA
TTGGTGGCTTGTATATTACGTTCGTATGTTTGGTTCCTTACGTGATGACATCAGCATGGAATGTACAGTTCTACTTTGGT
GGAACCTCTCTTCTGATTGTTGTCGTAGTAATTATGGATTTCATCGCTCAGGTTCAAAGTCATTTGATGTCGACGAAATA
TGAATCTGCGCTGAAGAAAGCAAACCTTAAAGGTTTCGGACAGTAA

Upstream 100 bases:

>100_bases
GAAGTGAAAGGTGCAGTGGTTGTTCGTGGTTTACGCGTAACTAAAGGTGCGAAAGCAGCAATTGAAGCTGCTGGCGGTTC
AGTTGAGGAATAATAAATAA

Downstream 100 bases:

>100_bases
TCTGTCCATTAAATAAAAGGGATAAGCAATGAAAGTTCGTGCTTCCGTGAAGAAATTATGTCGTAACTGTAAAATTGTTA
AACGTGAAGGTGTCGTTCGT

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MAKQPGYQSRSTQSGTGELKSRLLFVLGALIVFRIGSFIPVPGIDAAVLAQLVEQQKGTIIDMFNMFSGGALSRASIFAL
GIMPYISASIIIQLLTTVHPALAELKKEGEAGRRKISKYTRYSTLVLATLQAVGISTGLPNMLPGLVPNVGFSFYLAAVI
SLVTGTMFLMWLGEQITERGIGNGISLIIFAGIVAGLPSAIGQTIEQTRQGQMHLLVLLLIAVIVFAVTYFVVFVERGQR
RIKVEYAKRQQGRQILGGHSTHLPLKVNMAGVIPAIFASSIILFPATLAQWLGEGSSLEWLTDLSMLLHPGQPLYLLVYA
VAIIFFSFFYTAMQYNPRDTADNLKKSGAFIPGIRPGEQTSRYIDKIMTRLTLIGGLYITFVCLVPYVMTSAWNVQFYFG
GTSLLIVVVVIMDFIAQVQSHLMSTKYESALKKANLKGFGQ

Sequences:

>Translated_441_residues
MAKQPGYQSRSTQSGTGELKSRLLFVLGALIVFRIGSFIPVPGIDAAVLAQLVEQQKGTIIDMFNMFSGGALSRASIFAL
GIMPYISASIIIQLLTTVHPALAELKKEGEAGRRKISKYTRYSTLVLATLQAVGISTGLPNMLPGLVPNVGFSFYLAAVI
SLVTGTMFLMWLGEQITERGIGNGISLIIFAGIVAGLPSAIGQTIEQTRQGQMHLLVLLLIAVIVFAVTYFVVFVERGQR
RIKVEYAKRQQGRQILGGHSTHLPLKVNMAGVIPAIFASSIILFPATLAQWLGEGSSLEWLTDLSMLLHPGQPLYLLVYA
VAIIFFSFFYTAMQYNPRDTADNLKKSGAFIPGIRPGEQTSRYIDKIMTRLTLIGGLYITFVCLVPYVMTSAWNVQFYFG
GTSLLIVVVVIMDFIAQVQSHLMSTKYESALKKANLKGFGQ
>Mature_440_residues
AKQPGYQSRSTQSGTGELKSRLLFVLGALIVFRIGSFIPVPGIDAAVLAQLVEQQKGTIIDMFNMFSGGALSRASIFALG
IMPYISASIIIQLLTTVHPALAELKKEGEAGRRKISKYTRYSTLVLATLQAVGISTGLPNMLPGLVPNVGFSFYLAAVIS
LVTGTMFLMWLGEQITERGIGNGISLIIFAGIVAGLPSAIGQTIEQTRQGQMHLLVLLLIAVIVFAVTYFVVFVERGQRR
IKVEYAKRQQGRQILGGHSTHLPLKVNMAGVIPAIFASSIILFPATLAQWLGEGSSLEWLTDLSMLLHPGQPLYLLVYAV
AIIFFSFFYTAMQYNPRDTADNLKKSGAFIPGIRPGEQTSRYIDKIMTRLTLIGGLYITFVCLVPYVMTSAWNVQFYFGG
TSLLIVVVVIMDFIAQVQSHLMSTKYESALKKANLKGFGQ

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=443, Percent_Identity=77.6523702031603, Blast_Score=644, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48148; Mature: 48017

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKQPGYQSRSTQSGTGELKSRLLFVLGALIVFRIGSFIPVPGIDAAVLAQLVEQQKGTI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
IDMFNMFSGGALSRASIFALGIMPYISASIIIQLLTTVHPALAELKKEGEAGRRKISKYT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
RYSTLVLATLQAVGISTGLPNMLPGLVPNVGFSFYLAAVISLVTGTMFLMWLGEQITERG
HHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IGNGISLIIFAGIVAGLPSAIGQTIEQTRQGQMHLLVLLLIAVIVFAVTYFVVFVERGQR
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RIKVEYAKRQQGRQILGGHSTHLPLKVNMAGVIPAIFASSIILFPATLAQWLGEGSSLEW
EEHHHHHHHHCCHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LTDLSMLLHPGQPLYLLVYAVAIIFFSFFYTAMQYNPRDTADNLKKSGAFIPGIRPGEQT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHH
SRYIDKIMTRLTLIGGLYITFVCLVPYVMTSAWNVQFYFGGTSLLIVVVVIMDFIAQVQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
HLMSTKYESALKKANLKGFGQ
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]