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The map label for this gene is pepD [H]

Identifier: 15603233

GI number: 15603233

Start: 1559003

End: 1560505

Strand: Reverse

Name: pepD [H]

Synonym: PM1368

Alternate gene names: 15603233

Gene position: 1560505-1559003 (Counterclockwise)

Preceding gene: 15603235

Following gene: 15603231

Centisome position: 69.13

GC content: 42.25

Gene sequence:

>1503_bases
ATGAGCAGAACAGGCGTACATATTTCTGAAGAGGAGACCACAATGTCAGAAATCAAAACACTACAACCAACATTATTATG
GAAATGGTTTAGCCAAATTTGCGCTATTCCACATCCGTCTTATCATGAAGAGCAAATTGCACAATTCATTGTGCATTGGG
CAAAAGGCAAAGGGTTTTATGCTGAGCGTGATGAAGTCGGCAATATTTTGATTCGTAAACCTGCCAGTGCGGGTATGGAA
AACCATGTGCCGGTGGCATTACAAGCGCACTTAGACATGGTGCCTCAAGCGAATGAAGGTACCGTGCATGATTTTACCAA
AGATCCTATTCAACCTTATATTGATGGTGAGTGGGTAAAAGCAAAAGGGACAACACTTGGTGCGGATAATGGAATTGGTA
TGGCGTCTGCGTTAGCGGTGTTAGATAGTGATGATTTGGTACATCCCCCTTTAGAAGTCTTATTGACTATGACAGAAGAG
TCTGGCATGGAAGGTGCGATTGGGTTACGTCCAAATTGGTTACAAAGTGAAATCATGATCAACACCGATACGGAAGAAAA
CGGTGAAATCTACATTGGGTGTGCAGGCGGTGAAAATGCCAATATTACGTTGGAAATTGAGCGTAAACTGAATACTTTTG
AACAAAGTTATCAGCTTATTTTAAAAGGGCTTGCTGGTGGACATTCTGGCGGAGATATTCATACTGGACGGGCAAATGCG
ATTAAAGTGCTTGCTCGCTTCTTAGCCAAACTCACTCAAGATAAGCCAGACTTCCAATTTGCGTTAAGTGATATTCGCGG
TGGTTCAGTACGTAATGCGATTCCTCGCGAAGCCTTTGCAACACTTGCTTTTAATGAGGATTTAGCTACTTTACAACAAG
CAGTCAGTGAGTTTGAGGGGATATTAAAACATGAGTTAGTGAAAGTTGAACCTAATCTGTCATTGACGCTGAAACCTGTT
GAGAATGCGGATACGGTGTTTTCACAAAACACGACGCAAAAAGTCATTCATTTACTTAATGTACTGCCAAATGGCGTGAT
CCGTAATAGTGATGCGTTAGAGAATGTTGTGGAAAGTTCGTTAAGTATTGGTGTATTACGTACCGAAGAAAATGAAATTA
AAGGGACGATTTTGATTCGTTCACTCATTCATAGTGGTAATCGCTATATTGGCAGTTTATTAAAATCATTGGCCGCGTTA
ACAGGCGCAGAAATGACGCTGAGTGGCTATTATCCTGGTTGGGAGCCACATAATGATGCGCCTATCGTCGGATTAACGGA
AAAGGTCTATGCCGACGTCTTGGGCTATGCTCCGGTTGTGAAAGTCATCCATGCAGGCTTAGAATGCGGTTTACTGAAAA
AGATTTATCCAGATATGGATATGGTGTCAATTGGACCGACGATCCGTAATGCGCACTCACCAGATGAAAAAGTGCATATT
CCTACGGTACAAACGTATTGGGCGCTACTGACGAAGTTGTTAGCTGCGATTCCAGCAAAATAA

Upstream 100 bases:

>100_bases
AAAGAGGGGGTAAAATTTACCCATAAATTAAAAAATTGCGTTAGGATAACGCGAAATCGCCTTTTATGCTATAATTTTAC
TGATTTTTTTCGTATTTTTT

Downstream 100 bases:

>100_bases
GCATTAAACGAGCATAACAATGCGGTGAATATGTTGACATATTCACCGCATTTTTTCTTACACTAACAAAAGTTCAATAT
CCATTTCTTTAATCTTTTCT

Product: hypothetical protein

Products: NA

Alternate protein names: Beta-alanyl-histidine dipeptidase; Carnosinase; Peptidase D; Xaa-His dipeptidase; X-His dipeptidase [H]

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MSRTGVHISEEETTMSEIKTLQPTLLWKWFSQICAIPHPSYHEEQIAQFIVHWAKGKGFYAERDEVGNILIRKPASAGME
NHVPVALQAHLDMVPQANEGTVHDFTKDPIQPYIDGEWVKAKGTTLGADNGIGMASALAVLDSDDLVHPPLEVLLTMTEE
SGMEGAIGLRPNWLQSEIMINTDTEENGEIYIGCAGGENANITLEIERKLNTFEQSYQLILKGLAGGHSGGDIHTGRANA
IKVLARFLAKLTQDKPDFQFALSDIRGGSVRNAIPREAFATLAFNEDLATLQQAVSEFEGILKHELVKVEPNLSLTLKPV
ENADTVFSQNTTQKVIHLLNVLPNGVIRNSDALENVVESSLSIGVLRTEENEIKGTILIRSLIHSGNRYIGSLLKSLAAL
TGAEMTLSGYYPGWEPHNDAPIVGLTEKVYADVLGYAPVVKVIHAGLECGLLKKIYPDMDMVSIGPTIRNAHSPDEKVHI
PTVQTYWALLTKLLAAIPAK

Sequences:

>Translated_500_residues
MSRTGVHISEEETTMSEIKTLQPTLLWKWFSQICAIPHPSYHEEQIAQFIVHWAKGKGFYAERDEVGNILIRKPASAGME
NHVPVALQAHLDMVPQANEGTVHDFTKDPIQPYIDGEWVKAKGTTLGADNGIGMASALAVLDSDDLVHPPLEVLLTMTEE
SGMEGAIGLRPNWLQSEIMINTDTEENGEIYIGCAGGENANITLEIERKLNTFEQSYQLILKGLAGGHSGGDIHTGRANA
IKVLARFLAKLTQDKPDFQFALSDIRGGSVRNAIPREAFATLAFNEDLATLQQAVSEFEGILKHELVKVEPNLSLTLKPV
ENADTVFSQNTTQKVIHLLNVLPNGVIRNSDALENVVESSLSIGVLRTEENEIKGTILIRSLIHSGNRYIGSLLKSLAAL
TGAEMTLSGYYPGWEPHNDAPIVGLTEKVYADVLGYAPVVKVIHAGLECGLLKKIYPDMDMVSIGPTIRNAHSPDEKVHI
PTVQTYWALLTKLLAAIPAK
>Mature_499_residues
SRTGVHISEEETTMSEIKTLQPTLLWKWFSQICAIPHPSYHEEQIAQFIVHWAKGKGFYAERDEVGNILIRKPASAGMEN
HVPVALQAHLDMVPQANEGTVHDFTKDPIQPYIDGEWVKAKGTTLGADNGIGMASALAVLDSDDLVHPPLEVLLTMTEES
GMEGAIGLRPNWLQSEIMINTDTEENGEIYIGCAGGENANITLEIERKLNTFEQSYQLILKGLAGGHSGGDIHTGRANAI
KVLARFLAKLTQDKPDFQFALSDIRGGSVRNAIPREAFATLAFNEDLATLQQAVSEFEGILKHELVKVEPNLSLTLKPVE
NADTVFSQNTTQKVIHLLNVLPNGVIRNSDALENVVESSLSIGVLRTEENEIKGTILIRSLIHSGNRYIGSLLKSLAALT
GAEMTLSGYYPGWEPHNDAPIVGLTEKVYADVLGYAPVVKVIHAGLECGLLKKIYPDMDMVSIGPTIRNAHSPDEKVHIP
TVQTYWALLTKLLAAIPAK

Specific function: Dipeptidase with broad substrate specificity [H]

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20C family [H]

Homologues:

Organism=Escherichia coli, GI1786432, Length=488, Percent_Identity=58.1967213114754, Blast_Score=575, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR001160 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.13.3 [H]

Molecular weight: Translated: 54654; Mature: 54523

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTGVHISEEETTMSEIKTLQPTLLWKWFSQICAIPHPSYHEEQIAQFIVHWAKGKGFY
CCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
AERDEVGNILIRKPASAGMENHVPVALQAHLDMVPQANEGTVHDFTKDPIQPYIDGEWVK
CCHHHHCCEEEECCCCCCCCCCCCEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
AKGTTLGADNGIGMASALAVLDSDDLVHPPLEVLLTMTEESGMEGAIGLRPNWLQSEIMI
ECCCEECCCCCCCHHHHHHHCCCCCCCCCCHHHHEEHHHCCCCCCCCCCCCCCCCCEEEE
NTDTEENGEIYIGCAGGENANITLEIERKLNTFEQSYQLILKGLAGGHSGGDIHTGRANA
ECCCCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
IKVLARFLAKLTQDKPDFQFALSDIRGGSVRNAIPREAFATLAFNEDLATLQQAVSEFEG
HHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHH
ILKHELVKVEPNLSLTLKPVENADTVFSQNTTQKVIHLLNVLPNGVIRNSDALENVVESS
HHHHHHEEECCCCEEEEEECCCCHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LSIGVLRTEENEIKGTILIRSLIHSGNRYIGSLLKSLAALTGAEMTLSGYYPGWEPHNDA
HCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
PIVGLTEKVYADVLGYAPVVKVIHAGLECGLLKKIYPDMDMVSIGPTIRNAHSPDEKVHI
CEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEECCCHHCCCCCCCCEEEC
PTVQTYWALLTKLLAAIPAK
CHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRTGVHISEEETTMSEIKTLQPTLLWKWFSQICAIPHPSYHEEQIAQFIVHWAKGKGFY
CCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
AERDEVGNILIRKPASAGMENHVPVALQAHLDMVPQANEGTVHDFTKDPIQPYIDGEWVK
CCHHHHCCEEEECCCCCCCCCCCCEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
AKGTTLGADNGIGMASALAVLDSDDLVHPPLEVLLTMTEESGMEGAIGLRPNWLQSEIMI
ECCCEECCCCCCCHHHHHHHCCCCCCCCCCHHHHEEHHHCCCCCCCCCCCCCCCCCEEEE
NTDTEENGEIYIGCAGGENANITLEIERKLNTFEQSYQLILKGLAGGHSGGDIHTGRANA
ECCCCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
IKVLARFLAKLTQDKPDFQFALSDIRGGSVRNAIPREAFATLAFNEDLATLQQAVSEFEG
HHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHH
ILKHELVKVEPNLSLTLKPVENADTVFSQNTTQKVIHLLNVLPNGVIRNSDALENVVESS
HHHHHHEEECCCCEEEEEECCCCHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LSIGVLRTEENEIKGTILIRSLIHSGNRYIGSLLKSLAALTGAEMTLSGYYPGWEPHNDA
HCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
PIVGLTEKVYADVLGYAPVVKVIHAGLECGLLKKIYPDMDMVSIGPTIRNAHSPDEKVHI
CEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEECCCHHCCCCCCCCEEEC
PTVQTYWALLTKLLAAIPAK
CHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]