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The map label for this gene is nqrD

Identifier: 15603196

GI number: 15603196

Start: 1523750

End: 1524376

Strand: Direct

Name: nqrD

Synonym: PM1331

Alternate gene names: 15603196

Gene position: 1523750-1524376 (Clockwise)

Preceding gene: 15603195

Following gene: 15603197

Centisome position: 67.5

GC content: 38.6

Gene sequence:

>627_bases
ATGGCTGATACTAAAAAGTTAAAAGGCTTGTTGCTATCGCCAGTGATGGACAACAACCCGATTGCGTTACAAATTTTAGG
GATTTGTTCTGCGTTAGCGGTAACAACCAAATTAGAAACGGCAATTGTAATGACGTTTGCGGTAATTTTCGTTACGGCAT
TCTCAAACTTATTTATTTCTTTGATCCGTAACTATATTCCAAACAGTGTACGTATTATCGTGCAAATGGCGATTATCGCC
TCGTTGGTTATCTTAGTTGACCAAATCTTACGTGCTTATGCCTATGGTTTATCAAAACAACTTTCGGTTTTCGTGGGCTT
GATTATTACTAACTGTATCGTTATGGGACGAGCAGAAGCCTTTGCGATGAAATCACAACCACTAGAAAGTTTCGTTGATG
GGATTGGTAACGGCTTAGGTTATGGCGCAATTTTAGTGTCAGTTGCCTTTATCCGTGAATTAATTGGTTCAGGCAAATTA
TTTGGTATGACGGTATTCCAAACTATCCAAGATGGTGGTTGGTATCAAACCAATGGTTTATTCCTACTTGCACCAAGTGC
GTTCTTTATTATTGGTTTTATTATTTGGGGTATTCGTACCTTAAAACCAAATCAGGTGGAGAAGTAG

Upstream 100 bases:

>100_bases
ACATTAACCAGTAATGGTGTCAACAATTCATTTAAATTCTGGTTAGGTCAAAAAGGTTTTGGTCCTTTCTTAGCAAAACT
GAAAGCAGGAGTGTTGAACA

Downstream 100 bases:

>100_bases
TTTATGGAACATTATATTAGCCTTTTCGTTAAATCCGTTTTTATCGAAAACATGGCACTTTCTTTCTTCTTAGGAATGTG
TACTTTCCTTGCTGTATCGA

Product: Na(+)-translocating NADH-quinone reductase subunit D

Products: NA

Alternate protein names: Na(+)-NQR subunit D; Na(+)-translocating NQR subunit D; NQR complex subunit D; NQR-1 subunit D

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MADTKKLKGLLLSPVMDNNPIALQILGICSALAVTTKLETAIVMTFAVIFVTAFSNLFISLIRNYIPNSVRIIVQMAIIA
SLVILVDQILRAYAYGLSKQLSVFVGLIITNCIVMGRAEAFAMKSQPLESFVDGIGNGLGYGAILVSVAFIRELIGSGKL
FGMTVFQTIQDGGWYQTNGLFLLAPSAFFIIGFIIWGIRTLKPNQVEK

Sequences:

>Translated_208_residues
MADTKKLKGLLLSPVMDNNPIALQILGICSALAVTTKLETAIVMTFAVIFVTAFSNLFISLIRNYIPNSVRIIVQMAIIA
SLVILVDQILRAYAYGLSKQLSVFVGLIITNCIVMGRAEAFAMKSQPLESFVDGIGNGLGYGAILVSVAFIRELIGSGKL
FGMTVFQTIQDGGWYQTNGLFLLAPSAFFIIGFIIWGIRTLKPNQVEK
>Mature_207_residues
ADTKKLKGLLLSPVMDNNPIALQILGICSALAVTTKLETAIVMTFAVIFVTAFSNLFISLIRNYIPNSVRIIVQMAIIAS
LVILVDQILRAYAYGLSKQLSVFVGLIITNCIVMGRAEAFAMKSQPLESFVDGIGNGLGYGAILVSVAFIRELIGSGKLF
GMTVFQTIQDGGWYQTNGLFLLAPSAFFIIGFIIWGIRTLKPNQVEK

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1347

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrDE/rnfAE family

Homologues:

Organism=Escherichia coli, GI1787919, Length=205, Percent_Identity=37.0731707317073, Blast_Score=112, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRD_PASMU (Q9CLA8)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246269.1
- GeneID:   1244678
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1331
- NMPDR:   fig|272843.1.peg.1332
- HOGENOM:   HBG624915
- OMA:   GGWYVPN
- ProtClustDB:   PRK09292
- BioCyc:   PMUL272843:PM1331-MONOMER
- HAMAP:   MF_00428
- InterPro:   IPR003667
- InterPro:   IPR011292
- PIRSF:   PIRSF006102
- TIGRFAMs:   TIGR01939

Pfam domain/function: PF02508 Rnf-Nqr

EC number: NA

Molecular weight: Translated: 22586; Mature: 22455

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xda9ffec)-; HASH(0xe09ab08)-; HASH(0xeaa395c)-; HASH(0xe5dbd48)-; HASH(0xe58aa48)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTKKLKGLLLSPVMDNNPIALQILGICSALAVTTKLETAIVMTFAVIFVTAFSNLFIS
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIRNYIPNSVRIIVQMAIIASLVILVDQILRAYAYGLSKQLSVFVGLIITNCIVMGRAEA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
FAMKSQPLESFVDGIGNGLGYGAILVSVAFIRELIGSGKLFGMTVFQTIQDGGWYQTNGL
HHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCE
FLLAPSAFFIIGFIIWGIRTLKPNQVEK
EEECCHHHHHHHHHHHHHHCCCCCCCCH
>Mature Secondary Structure 
ADTKKLKGLLLSPVMDNNPIALQILGICSALAVTTKLETAIVMTFAVIFVTAFSNLFIS
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIRNYIPNSVRIIVQMAIIASLVILVDQILRAYAYGLSKQLSVFVGLIITNCIVMGRAEA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
FAMKSQPLESFVDGIGNGLGYGAILVSVAFIRELIGSGKLFGMTVFQTIQDGGWYQTNGL
HHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCE
FLLAPSAFFIIGFIIWGIRTLKPNQVEK
EEECCHHHHHHHHHHHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100