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The map label for this gene is kdkA

Identifier: 15603168

GI number: 15603168

Start: 1498243

End: 1498965

Strand: Direct

Name: kdkA

Synonym: PM1303

Alternate gene names: 15603168

Gene position: 1498243-1498965 (Clockwise)

Preceding gene: 15603165

Following gene: 15603171

Centisome position: 66.37

GC content: 39.14

Gene sequence:

>723_bases
ATGCTTGAATTTAAACACAAAAATACGTTTTTCTTGTTTAACTTTAAACAACCTAAAGCACAGCAGGCGTGCTTTTTTCG
ATCTTCATTTTGGAAAAAACAAGCGCGTATTCTTGGTTCCGCACAGGGACGAGGCGTAACGTGGTTTTTACAAACAAAAG
ATTTGTTTGGTGTCAACGCAGCATTAAAACATTATTACCGTGGCGGGTTATGGGGCAAAATTAATCGAGATTATTATCGT
TTCTCAACCTTATCTAATGCGCGTAGTTTTGCGGAGTTTTCGTTGTTAAAACAACTTCATGAAGCAGGGCTCGCTGTTCC
AAAGCCCCTTGGCGCTTGTGTGGAAAAAGTCGCATTTGGTTTTTATCGTGCTGATTTGTTAACAGAAAAAATTGAGCATG
CACAAGATCTCACTGTCTATTTACAACAAGGTAAGCTGACGGAACAAGATTGGCACAAAGTCGGACAACTCATTCATCAA
TTACACAGTTTGCAAGTGTGCCATACCGACTTAAATGCGCACAATATTTTGGTACAACAACGAGACGATGGGCGTAAATT
CTGGTTAATTGATTTTGATAAATGTGCACATCAGCTTGGTGAACGTTGGAAAAGTGAAAATTTAAACAGATTACACCGCT
CTTTTATGAAAGAAGTGACGCGGATGAAAATTCAATTCAGTGAACAAGACTGGCAAGCTTTGTTAGCGGGATATCAAGCA
TAA

Upstream 100 bases:

>100_bases
CAGCGGCATCATTATCTCGTCCAATAAATCTTGTGTGAATTTTAACTATTTTAAAGTAGAATGTGACCATTCGCTATCTC
TGATTTCATCTAATAAAAAT

Downstream 100 bases:

>100_bases
GGGGAAAACATATTTCCCCTTTTTTCATCGTAGTGAACTATTTTTTTAAGTTTTGTAAGGCGTGAAAAACGACTTCGGGC
ACGAGTTGACTTACATCGCC

Product: 3-deoxy-D-manno-octulosonic-acid kinase

Products: NA

Alternate protein names: KDO kinase

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MLEFKHKNTFFLFNFKQPKAQQACFFRSSFWKKQARILGSAQGRGVTWFLQTKDLFGVNAALKHYYRGGLWGKINRDYYR
FSTLSNARSFAEFSLLKQLHEAGLAVPKPLGACVEKVAFGFYRADLLTEKIEHAQDLTVYLQQGKLTEQDWHKVGQLIHQ
LHSLQVCHTDLNAHNILVQQRDDGRKFWLIDFDKCAHQLGERWKSENLNRLHRSFMKEVTRMKIQFSEQDWQALLAGYQA

Sequences:

>Translated_240_residues
MLEFKHKNTFFLFNFKQPKAQQACFFRSSFWKKQARILGSAQGRGVTWFLQTKDLFGVNAALKHYYRGGLWGKINRDYYR
FSTLSNARSFAEFSLLKQLHEAGLAVPKPLGACVEKVAFGFYRADLLTEKIEHAQDLTVYLQQGKLTEQDWHKVGQLIHQ
LHSLQVCHTDLNAHNILVQQRDDGRKFWLIDFDKCAHQLGERWKSENLNRLHRSFMKEVTRMKIQFSEQDWQALLAGYQA
>Mature_240_residues
MLEFKHKNTFFLFNFKQPKAQQACFFRSSFWKKQARILGSAQGRGVTWFLQTKDLFGVNAALKHYYRGGLWGKINRDYYR
FSTLSNARSFAEFSLLKQLHEAGLAVPKPLGACVEKVAFGFYRADLLTEKIEHAQDLTVYLQQGKLTEQDWHKVGQLIHQ
LHSLQVCHTDLNAHNILVQQRDDGRKFWLIDFDKCAHQLGERWKSENLNRLHRSFMKEVTRMKIQFSEQDWQALLAGYQA

Specific function: ATP-dependent phosphorylation of 3-deoxy-D-manno- octulosonic acid at the 4-OH position

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. KdkA/rfaP family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDKA_PASMU (Q9CLD5)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246241.1
- ProteinModelPortal:   Q9CLD5
- GeneID:   1244650
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1303
- NMPDR:   fig|272843.1.peg.1304
- HOGENOM:   HBG353234
- OMA:   VYHADLN
- ProtClustDB:   PRK01723
- BioCyc:   PMUL272843:PM1303-MONOMER
- HAMAP:   MF_00521
- InterPro:   IPR022826
- InterPro:   IPR011009
- InterPro:   IPR010440

Pfam domain/function: PF06293 Kdo; SSF56112 Kinase_like

EC number: NA

Molecular weight: Translated: 28160; Mature: 28160

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: ACT_SITE 170-170

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEFKHKNTFFLFNFKQPKAQQACFFRSSFWKKQARILGSAQGRGVTWFLQTKDLFGVNA
CCEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHH
ALKHYYRGGLWGKINRDYYRFSTLSNARSFAEFSLLKQLHEAGLAVPKPLGACVEKVAFG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
FYRADLLTEKIEHAQDLTVYLQQGKLTEQDWHKVGQLIHQLHSLQVCHTDLNAHNILVQQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
RDDGRKFWLIDFDKCAHQLGERWKSENLNRLHRSFMKEVTRMKIQFSEQDWQALLAGYQA
CCCCCEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLEFKHKNTFFLFNFKQPKAQQACFFRSSFWKKQARILGSAQGRGVTWFLQTKDLFGVNA
CCEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHH
ALKHYYRGGLWGKINRDYYRFSTLSNARSFAEFSLLKQLHEAGLAVPKPLGACVEKVAFG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
FYRADLLTEKIEHAQDLTVYLQQGKLTEQDWHKVGQLIHQLHSLQVCHTDLNAHNILVQQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
RDDGRKFWLIDFDKCAHQLGERWKSENLNRLHRSFMKEVTRMKIQFSEQDWQALLAGYQA
CCCCCEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100