Click here to switch to the map view.

The map label for this gene is metJ [H]

Identifier: 15603155

GI number: 15603155

Start: 1485430

End: 1485747

Strand: Direct

Name: metJ [H]

Synonym: PM1290

Alternate gene names: 15603155

Gene position: 1485430-1485747 (Clockwise)

Preceding gene: 15603154

Following gene: 15603158

Centisome position: 65.8

GC content: 41.19

Gene sequence:

>318_bases
ATGGCAAATTGGGACGGTAAATATATTAGCCCTTACGCAGAGCATGGCAAGAAGAGTGAGCAAGTCAAAAAAATTACAGT
ATCGATTCCGATTAAAGTATTGGAAATTTTAACCAATGAACGGACACGCAGACAAATTCGTAATTTACGTCATGCAACGA
ACAGTGAATTGCTCTGTGAAGCCTTTTTGCATGCCTTTACCGGTCAACCGTTGCCAACGGATGAAGACTTATTAAAAGAG
CGCCATGACGAAATTCCTGAGCAAGCAAAGCAAGTGATGCGCGAATTGGGTATCGATCCAGAAAAATGGGAATACTAA

Upstream 100 bases:

>100_bases
GACGGATATCTAGCAATCTTAACGTCTAGATTGTCATTGCGCTTATTTTTCATTAAAATGCCCCATAATTATTATGTCTA
TTTATTAACAGGATAAAAAA

Downstream 100 bases:

>100_bases
TTTAAAGAATTGAAAAAGTGCGGTGAGAATAACGAAAATTCTGACCGCACTTTCTTATGTATCTAATAGGTAGAATTACG
CGTTATCGCCAATTAGAACG

Product: transcriptional repressor protein MetJ

Products: NA

Alternate protein names: Met regulon regulatory protein metJ [H]

Number of amino acids: Translated: 105; Mature: 104

Protein sequence:

>105_residues
MANWDGKYISPYAEHGKKSEQVKKITVSIPIKVLEILTNERTRRQIRNLRHATNSELLCEAFLHAFTGQPLPTDEDLLKE
RHDEIPEQAKQVMRELGIDPEKWEY

Sequences:

>Translated_105_residues
MANWDGKYISPYAEHGKKSEQVKKITVSIPIKVLEILTNERTRRQIRNLRHATNSELLCEAFLHAFTGQPLPTDEDLLKE
RHDEIPEQAKQVMRELGIDPEKWEY
>Mature_104_residues
ANWDGKYISPYAEHGKKSEQVKKITVSIPIKVLEILTNERTRRQIRNLRHATNSELLCEAFLHAFTGQPLPTDEDLLKER
HDEIPEQAKQVMRELGIDPEKWEY

Specific function: This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis [H]

COG id: COG3060

COG function: function code KE; Transcriptional regulator of met regulon

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metJ family [H]

Homologues:

Organism=Escherichia coli, GI1790373, Length=105, Percent_Identity=82.8571428571429, Blast_Score=188, Evalue=8e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002084
- InterPro:   IPR010985
- ProDom:   PD020365 [H]

Pfam domain/function: PF01340 MetJ [H]

EC number: NA

Molecular weight: Translated: 12312; Mature: 12181

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANWDGKYISPYAEHGKKSEQVKKITVSIPIKVLEILTNERTRRQIRNLRHATNSELLCE
CCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHH
AFLHAFTGQPLPTDEDLLKERHDEIPEQAKQVMRELGIDPEKWEY
HHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ANWDGKYISPYAEHGKKSEQVKKITVSIPIKVLEILTNERTRRQIRNLRHATNSELLCE
CCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHH
AFLHAFTGQPLPTDEDLLKERHDEIPEQAKQVMRELGIDPEKWEY
HHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA