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The map label for this gene is hmuU [H]

Identifier: 15602944

GI number: 15602944

Start: 1270404

End: 1271348

Strand: Direct

Name: hmuU [H]

Synonym: PM1079

Alternate gene names: 15602944

Gene position: 1270404-1271348 (Clockwise)

Preceding gene: 15602943

Following gene: 15602945

Centisome position: 56.28

GC content: 46.46

Gene sequence:

>945_bases
ATGAAAAAACTGTCTGTCTTTTTGGCCATATTGGGAACCGTATTACTGATTTGGTTTTCAACTGGCGTGGGCTTTGGTGG
TTGGCAGCCACCAAACGCCCTTGATCCCATCGTTTTTGATATCCGCATTCCTCGTATTCTCAATGCCTTACTCGTTGGCG
CAGCACTCGCGGCAGCGGGTGCCGGGCTGCAAGCCTTATTTGAAAATCCCTTAGCCGATCCCAGTTTGATTGGCACCTCT
GGCGGTGCCGCGTTAGGCGTCATTTGTGTACTGGCATTTGGAAGCCTTGGCATTGGCGTACCTCTTGCCGCCTTTGTCGG
TGCGTTAGTAGTTTGCTTAGTGATATTATTTGCTCATCACGTATTCGGGGGAGGTACGTTGGGTTTGTTAATCATGGGAT
TTATCCTCAGTGCCTTTTGTTCCGCTGTGGTAGGGCTTATCCTATTTTTATCCGATGATCTTGTGCTACGCAGCGCTACC
ATTTGGTTAGCTGGTAGCTTATCAGAAGCCGGCTTTACCCCTATTTACTACCCTTTCGCCATTATGTTGATTGGCTTAGT
TTGGATGGCTATTTTAGGTCGCCAGCTTGATTGCTTGATGCTTGGTGAAGACACCGCCTTTACCATGGGGATATCCGTAT
CCAAACTCCGCTTACAAACTGTCATTGCTGCCGCTTTATTAACCGGTGCTGCTGTTTCTTTATCTGGTATTATTGGTTTT
TTAGGCATGATGATCCCGAATATTTTAACAACTGTCATCGGCGGACATCGCCGTAAACTGATTTTATTATCCGCTTGGGT
GGGTGCTGTATTTTTATTAGCGGTGGATAGTGCTTCTCGTCTTATCACTTATCCCATTGATCTGCCTGTGGGCATTGTGA
TTGCCTTACTTGGTGGTCCTTTCTTCTTCTGGATCTTTATCCAGTCAACACAACGTAAAGTGTAA

Upstream 100 bases:

>100_bases
TATTTACTTCTGGTCTGCTAATGATTACTTACGTTATGGATTAAACACCCCTGAAGTGTTAAAACGTTTACATGATTTAG
CGAAGTAATCTGCATTCCGA

Downstream 100 bases:

>100_bases
GGAACCGTTGTATGCAAGCACTCTTTGAATTACAACCCTTATCCCTAAAGGCAAATGAGCGGGTAATTTTACAAACTGAT
CAGTTAACCATTCCACAGGG

Product: hypothetical protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKKLSVFLAILGTVLLIWFSTGVGFGGWQPPNALDPIVFDIRIPRILNALLVGAALAAAGAGLQALFENPLADPSLIGTS
GGAALGVICVLAFGSLGIGVPLAAFVGALVVCLVILFAHHVFGGGTLGLLIMGFILSAFCSAVVGLILFLSDDLVLRSAT
IWLAGSLSEAGFTPIYYPFAIMLIGLVWMAILGRQLDCLMLGEDTAFTMGISVSKLRLQTVIAAALLTGAAVSLSGIIGF
LGMMIPNILTTVIGGHRRKLILLSAWVGAVFLLAVDSASRLITYPIDLPVGIVIALLGGPFFFWIFIQSTQRKV

Sequences:

>Translated_314_residues
MKKLSVFLAILGTVLLIWFSTGVGFGGWQPPNALDPIVFDIRIPRILNALLVGAALAAAGAGLQALFENPLADPSLIGTS
GGAALGVICVLAFGSLGIGVPLAAFVGALVVCLVILFAHHVFGGGTLGLLIMGFILSAFCSAVVGLILFLSDDLVLRSAT
IWLAGSLSEAGFTPIYYPFAIMLIGLVWMAILGRQLDCLMLGEDTAFTMGISVSKLRLQTVIAAALLTGAAVSLSGIIGF
LGMMIPNILTTVIGGHRRKLILLSAWVGAVFLLAVDSASRLITYPIDLPVGIVIALLGGPFFFWIFIQSTQRKV
>Mature_314_residues
MKKLSVFLAILGTVLLIWFSTGVGFGGWQPPNALDPIVFDIRIPRILNALLVGAALAAAGAGLQALFENPLADPSLIGTS
GGAALGVICVLAFGSLGIGVPLAAFVGALVVCLVILFAHHVFGGGTLGLLIMGFILSAFCSAVVGLILFLSDDLVLRSAT
IWLAGSLSEAGFTPIYYPFAIMLIGLVWMAILGRQLDCLMLGEDTAFTMGISVSKLRLQTVIAAALLTGAAVSLSGIIGF
LGMMIPNILTTVIGGHRRKLILLSAWVGAVFLLAVDSASRLITYPIDLPVGIVIALLGGPFFFWIFIQSTQRKV

Specific function: Part of the binding-protein-dependent transport system for hemin; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=287, Percent_Identity=34.8432055749129, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788004, Length=288, Percent_Identity=36.1111111111111, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1790741, Length=284, Percent_Identity=33.0985915492958, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786804, Length=284, Percent_Identity=32.7464788732394, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786347, Length=278, Percent_Identity=32.3741007194245, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786805, Length=280, Percent_Identity=34.2857142857143, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 32752; Mature: 32752

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLSVFLAILGTVLLIWFSTGVGFGGWQPPNALDPIVFDIRIPRILNALLVGAALAAAG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHC
AGLQALFENPLADPSLIGTSGGAALGVICVLAFGSLGIGVPLAAFVGALVVCLVILFAHH
CCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VFGGGTLGLLIMGFILSAFCSAVVGLILFLSDDLVLRSATIWLAGSLSEAGFTPIYYPFA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEECCCCCCCCHHHHHHH
IMLIGLVWMAILGRQLDCLMLGEDTAFTMGISVSKLRLQTVIAAALLTGAAVSLSGIIGF
HHHHHHHHHHHHCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMMIPNILTTVIGGHRRKLILLSAWVGAVFLLAVDSASRLITYPIDLPVGIVIALLGGP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCH
FFFWIFIQSTQRKV
HHHHEEEEHHCCCC
>Mature Secondary Structure
MKKLSVFLAILGTVLLIWFSTGVGFGGWQPPNALDPIVFDIRIPRILNALLVGAALAAAG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHC
AGLQALFENPLADPSLIGTSGGAALGVICVLAFGSLGIGVPLAAFVGALVVCLVILFAHH
CCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VFGGGTLGLLIMGFILSAFCSAVVGLILFLSDDLVLRSATIWLAGSLSEAGFTPIYYPFA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEECCCCCCCCHHHHHHH
IMLIGLVWMAILGRQLDCLMLGEDTAFTMGISVSKLRLQTVIAAALLTGAAVSLSGIIGF
HHHHHHHHHHHHCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMMIPNILTTVIGGHRRKLILLSAWVGAVFLLAVDSASRLITYPIDLPVGIVIALLGGP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCH
FFFWIFIQSTQRKV
HHHHEEEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]