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The map label for this gene is mglB [H]

Identifier: 15602903

GI number: 15602903

Start: 1221315

End: 1222307

Strand: Direct

Name: mglB [H]

Synonym: PM1038

Alternate gene names: 15602903

Gene position: 1221315-1222307 (Clockwise)

Preceding gene: 15602902

Following gene: 15602904

Centisome position: 54.1

GC content: 39.88

Gene sequence:

>993_bases
ATGAAAAAAACCGTATTAAGTGCTGTTGCTTTAGCAGTCGGTCTAGGCGTAGCCGCTTCAGCAGCGCAAGCCGCCGATCG
TATTGGTGTAACCATTTACAAATATGATGATAACTTCATGTCACTCATGCGTAAAGAAATCAATAAAGAAGCTGAGCAAT
TTAAAGATATTGAGTTATTAATGAACGACTCACAAAACGCACAAGCGGTACAAAATGACCAAGTGGATGGTTTAATTTCT
AAAGGCGTTAAAGCCTTAGCCATTAACCTCGTTGACCCAGCGGCAGCACCAACTATTATCGGTAAAGCAAAACCTGATGA
TATTCCTGTTGTGTTCTTTAATAAAGATCCTGGTGCAAAAGCAATCGGTAGCTATGAACATGCATACTATGTGGGTACCG
ATCCAAAAGAGTCTGGTTTAATTCAAGGTTCATTGATTGCTAAACACTGGCAAGCTAACCCTGCATATGACTTAAATAAA
GACGGTAAAATTCAATACGTTTTATTAAAAGGTGAACCAGGACACCCAGATGCAGAAGCTCGTACAAAATTCGTCATTGA
AGAATTAAATAATAAAGGCATTCAAACTGAGCAATTATTCATCGACACGGGGATGTGGGATGCCGCTTTAGCGAAAGATA
AAATGGATGCATGGTTATCTAGCTCTAAAGCAAATCAAATCGAAGTGATCATCGCTAACAACGATGGTATGGCGATGGGG
GCATTGGAAGCCACGAAAGCACATGGTAAAAAATTACCAATCTTCGGTGTAGATGCGTTACCAGAAGTCCTCCAGTTAAT
CAAAAAAGGTGAAATTGCAGGTACGGTGTTAAATGACGGTGTGAACCAAGGTAAAGCCGTTGTTCAATTAAGTAATAATC
TTGCAAAAGGAAAACCTGCCACTGAAGGCACAAAATGGCAGTTAAAAGATCGTGTAGTACGTATCCCTTATGTTGGTGTG
GATGCGGATAACTTAAACGAGTTCCTAAAATAA

Upstream 100 bases:

>100_bases
GGAAAATATTTTCCAGTATGATTCACCCCAGTTATCTAGGCAAAGTGGGTTAAACGCAAAAAGATAACAAAATCTATTCG
TTCTAAATAGGAGAGTTATT

Downstream 100 bases:

>100_bases
TAAACTATAACAAAACAAGAAGTTGTAATTCTCGGGGAGGTATACCCTCCCCCTTTTTATGTGAGGTTGGATATGACAAC
TCAAATTCCAAATCAAGACA

Product: MglB

Products: ADP; phosphate; beta-D-galactose [Cytoplasm] [C]

Alternate protein names: GBP; D-galactose/ D-glucose-binding protein; GGBP [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKKTVLSAVALAVGLGVAASAAQAADRIGVTIYKYDDNFMSLMRKEINKEAEQFKDIELLMNDSQNAQAVQNDQVDGLIS
KGVKALAINLVDPAAAPTIIGKAKPDDIPVVFFNKDPGAKAIGSYEHAYYVGTDPKESGLIQGSLIAKHWQANPAYDLNK
DGKIQYVLLKGEPGHPDAEARTKFVIEELNNKGIQTEQLFIDTGMWDAALAKDKMDAWLSSSKANQIEVIIANNDGMAMG
ALEATKAHGKKLPIFGVDALPEVLQLIKKGEIAGTVLNDGVNQGKAVVQLSNNLAKGKPATEGTKWQLKDRVVRIPYVGV
DADNLNEFLK

Sequences:

>Translated_330_residues
MKKTVLSAVALAVGLGVAASAAQAADRIGVTIYKYDDNFMSLMRKEINKEAEQFKDIELLMNDSQNAQAVQNDQVDGLIS
KGVKALAINLVDPAAAPTIIGKAKPDDIPVVFFNKDPGAKAIGSYEHAYYVGTDPKESGLIQGSLIAKHWQANPAYDLNK
DGKIQYVLLKGEPGHPDAEARTKFVIEELNNKGIQTEQLFIDTGMWDAALAKDKMDAWLSSSKANQIEVIIANNDGMAMG
ALEATKAHGKKLPIFGVDALPEVLQLIKKGEIAGTVLNDGVNQGKAVVQLSNNLAKGKPATEGTKWQLKDRVVRIPYVGV
DADNLNEFLK
>Mature_330_residues
MKKTVLSAVALAVGLGVAASAAQAADRIGVTIYKYDDNFMSLMRKEINKEAEQFKDIELLMNDSQNAQAVQNDQVDGLIS
KGVKALAINLVDPAAAPTIIGKAKPDDIPVVFFNKDPGAKAIGSYEHAYYVGTDPKESGLIQGSLIAKHWQANPAYDLNK
DGKIQYVLLKGEPGHPDAEARTKFVIEELNNKGIQTEQLFIDTGMWDAALAKDKMDAWLSSSKANQIEVIIANNDGMAMG
ALEATKAHGKKLPIFGVDALPEVLQLIKKGEIAGTVLNDGVNQGKAVVQLSNNLAKGKPATEGTKWQLKDRVVRIPYVGV
DADNLNEFLK

Specific function: This protein is involved in the active transport of galactose and glucose [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788473, Length=331, Percent_Identity=66.1631419939577, Blast_Score=445, Evalue=1e-126,

Paralogues:

None

Copy number: 4720 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 1320 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001761 [H]

Pfam domain/function: PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35567; Mature: 35567

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTVLSAVALAVGLGVAASAAQAADRIGVTIYKYDDNFMSLMRKEINKEAEQFKDIELL
CCHHHHHHHHHHHHHCHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHEE
MNDSQNAQAVQNDQVDGLISKGVKALAINLVDPAAAPTIIGKAKPDDIPVVFFNKDPGAK
ECCCCCCHHHHCCCHHHHHHCCCEEEEEEECCCCCCCEEECCCCCCCCCEEEECCCCCCH
AIGSYEHAYYVGTDPKESGLIQGSLIAKHWQANPAYDLNKDGKIQYVLLKGEPGHPDAEA
HCCCCCCEEEECCCCCCCCCEEHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCHHH
RTKFVIEELNNKGIQTEQLFIDTGMWDAALAKDKMDAWLSSSKANQIEVIIANNDGMAMG
HHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEE
ALEATKAHGKKLPIFGVDALPEVLQLIKKGEIAGTVLNDGVNQGKAVVQLSNNLAKGKPA
HHHHHHHCCCCCCEECCHHHHHHHHHHHCCCCEEEHHHCCCCCCEEEEEECCCCCCCCCC
TEGTKWQLKDRVVRIPYVGVDADNLNEFLK
CCCCCEEECCCEEEEEEECCCHHHHHHHCC
>Mature Secondary Structure
MKKTVLSAVALAVGLGVAASAAQAADRIGVTIYKYDDNFMSLMRKEINKEAEQFKDIELL
CCHHHHHHHHHHHHHCHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHEE
MNDSQNAQAVQNDQVDGLISKGVKALAINLVDPAAAPTIIGKAKPDDIPVVFFNKDPGAK
ECCCCCCHHHHCCCHHHHHHCCCEEEEEEECCCCCCCEEECCCCCCCCCEEEECCCCCCH
AIGSYEHAYYVGTDPKESGLIQGSLIAKHWQANPAYDLNKDGKIQYVLLKGEPGHPDAEA
HCCCCCCEEEECCCCCCCCCEEHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCHHH
RTKFVIEELNNKGIQTEQLFIDTGMWDAALAKDKMDAWLSSSKANQIEVIIANNDGMAMG
HHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEE
ALEATKAHGKKLPIFGVDALPEVLQLIKKGEIAGTVLNDGVNQGKAVVQLSNNLAKGKPA
HHHHHHHCCCCCCEECCHHHHHHHHHHHCCCCEEEHHHCCCCCCEEEEEECCCCCCCCCC
TEGTKWQLKDRVVRIPYVGVDADNLNEFLK
CCCCCEEECCCEEEEEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; beta-D-galactose [Periplasm]; H2O [C]

Specific reaction: ATP + beta-D-galactose [Periplasm] + H2O = ADP + phosphate + beta-D-galactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]