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The map label for this gene is sapC [H]

Identifier: 15602778

GI number: 15602778

Start: 1072843

End: 1073730

Strand: Direct

Name: sapC [H]

Synonym: PM0913

Alternate gene names: 15602778

Gene position: 1072843-1073730 (Clockwise)

Preceding gene: 15602777

Following gene: 15602779

Centisome position: 47.52

GC content: 38.85

Gene sequence:

>888_bases
ATGCAAGATAAAGAACCTGATGAATTTCGCGAAAGTGCTGCAATAAAACATATCTGGCTATTATTTAGACAAGATCGTAT
CGCGCTATTTAGCTTCTACCTTTTTATTGTTTTTATTTTAACCGCACTTTTTAGTCCGTGGATTGCACCTTACTCTAGCG
ACATGCAATTTGTCGGTCAAGAACTGCTGCCTCCTTCTTGGACCAACGAAGGAAAAATTTCGTTTTTTTTCGGTACTGAT
GATATTGGCAGAGATGTTTTTAGTCGTATCATTATCGGTACTAGCTATACACTCGGCGCTTCTCTCGTTGTTGTGTGTTT
CACTATCATGATTGGGACATTACTCGGCATTTGGGCGGGTATTTCACACAGTGTAAAATCAAAAATTTTAGGGCATTTTC
TTGATACGTTTCTTTCGATCCCGAGTTTGTTGATTGCTATTATTATTGCGACGCTAATGAAGCCTAGCTTAATTAATGCC
ATTTTAGCCACAACATTAGCATTATTGCCGTACTTTATTCATGAAATCTATCAAGCCACACAACATGAACTGAAAAAAGA
ATATGTATTAATGCTTAAACTAGATGGAATTTCGAATAAAGCACTCCTGAAAGAAATCATCTTGCCGAATATTTCAGTAC
GTTATATTCAGGAAATCGCTCGTGCCTTTGCCATCGCTATTTTAGATATCAGCGCACTCAGTTTTATCTCTTTGGGGGCA
CAGCGCCCTACGCCAGAATGGGGTGCAATGATCAAAGATTCTTTAGAACTGATTTATCTCGCGCCTTGGACCGTCATTCT
CCCCGGCATCGCCATTATTTTAACCATTTTAGTCGTTTTTATTTTCAGCCAAGGCCTGTGTAAAGCGATAGAGAAATATT
ACGAGTAG

Upstream 100 bases:

>100_bases
TCTGTGGGCGTGATCGTTATTGGCTTATGTATTATCATCGTTGATGTATTATCAGAAAGTTTTGCCTTTATGCTCGATCC
ATTTAATAAGAAAGGCTGGT

Downstream 100 bases:

>100_bases
GTGAATCATGGCGCTATTAGATATTCGAAACCTGTGTATTGAAATTGAAACATCGCAAGGGCGTATCAAGGTTGTCGATA
ATGTCAATCTTACCCTTAAC

Product: SapC

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MQDKEPDEFRESAAIKHIWLLFRQDRIALFSFYLFIVFILTALFSPWIAPYSSDMQFVGQELLPPSWTNEGKISFFFGTD
DIGRDVFSRIIIGTSYTLGASLVVVCFTIMIGTLLGIWAGISHSVKSKILGHFLDTFLSIPSLLIAIIIATLMKPSLINA
ILATTLALLPYFIHEIYQATQHELKKEYVLMLKLDGISNKALLKEIILPNISVRYIQEIARAFAIAILDISALSFISLGA
QRPTPEWGAMIKDSLELIYLAPWTVILPGIAIILTILVVFIFSQGLCKAIEKYYE

Sequences:

>Translated_295_residues
MQDKEPDEFRESAAIKHIWLLFRQDRIALFSFYLFIVFILTALFSPWIAPYSSDMQFVGQELLPPSWTNEGKISFFFGTD
DIGRDVFSRIIIGTSYTLGASLVVVCFTIMIGTLLGIWAGISHSVKSKILGHFLDTFLSIPSLLIAIIIATLMKPSLINA
ILATTLALLPYFIHEIYQATQHELKKEYVLMLKLDGISNKALLKEIILPNISVRYIQEIARAFAIAILDISALSFISLGA
QRPTPEWGAMIKDSLELIYLAPWTVILPGIAIILTILVVFIFSQGLCKAIEKYYE
>Mature_295_residues
MQDKEPDEFRESAAIKHIWLLFRQDRIALFSFYLFIVFILTALFSPWIAPYSSDMQFVGQELLPPSWTNEGKISFFFGTD
DIGRDVFSRIIIGTSYTLGASLVVVCFTIMIGTLLGIWAGISHSVKSKILGHFLDTFLSIPSLLIAIIIATLMKPSLINA
ILATTLALLPYFIHEIYQATQHELKKEYVLMLKLDGISNKALLKEIILPNISVRYIQEIARAFAIAILDISALSFISLGA
QRPTPEWGAMIKDSLELIYLAPWTVILPGIAIILTILVVFIFSQGLCKAIEKYYE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=288, Percent_Identity=46.1805555555556, Blast_Score=275, Evalue=2e-75,
Organism=Escherichia coli, GI1789964, Length=277, Percent_Identity=34.2960288808664, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1787760, Length=282, Percent_Identity=32.2695035460993, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1787054, Length=287, Percent_Identity=29.2682926829268, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1789889, Length=253, Percent_Identity=23.3201581027668, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787498, Length=270, Percent_Identity=24.0740740740741, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33156; Mature: 33156

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDKEPDEFRESAAIKHIWLLFRQDRIALFSFYLFIVFILTALFSPWIAPYSSDMQFVGQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ELLPPSWTNEGKISFFFGTDDIGRDVFSRIIIGTSYTLGASLVVVCFTIMIGTLLGIWAG
HHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ISHSVKSKILGHFLDTFLSIPSLLIAIIIATLMKPSLINAILATTLALLPYFIHEIYQAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
QHELKKEYVLMLKLDGISNKALLKEIILPNISVRYIQEIARAFAIAILDISALSFISLGA
HHHHHHHHEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QRPTPEWGAMIKDSLELIYLAPWTVILPGIAIILTILVVFIFSQGLCKAIEKYYE
CCCCCHHHHHHHHCHHEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDKEPDEFRESAAIKHIWLLFRQDRIALFSFYLFIVFILTALFSPWIAPYSSDMQFVGQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ELLPPSWTNEGKISFFFGTDDIGRDVFSRIIIGTSYTLGASLVVVCFTIMIGTLLGIWAG
HHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ISHSVKSKILGHFLDTFLSIPSLLIAIIIATLMKPSLINAILATTLALLPYFIHEIYQAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
QHELKKEYVLMLKLDGISNKALLKEIILPNISVRYIQEIARAFAIAILDISALSFISLGA
HHHHHHHHEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QRPTPEWGAMIKDSLELIYLAPWTVILPGIAIILTILVVFIFSQGLCKAIEKYYE
CCCCCHHHHHHHHCHHEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]