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The map label for this gene is sapA [H]

Identifier: 15602776

GI number: 15602776

Start: 1070200

End: 1071891

Strand: Direct

Name: sapA [H]

Synonym: PM0911

Alternate gene names: 15602776

Gene position: 1070200-1071891 (Clockwise)

Preceding gene: 15602772

Following gene: 15602777

Centisome position: 47.41

GC content: 38.89

Gene sequence:

>1692_bases
ATGTTGATTAGAAAAGTTATCTTTGCCTGTTTTCTCTTTCTCTACTCACATTTTGTTACGGCGGCGCCACGCGTGCCCAA
TGAGCTAACACAAAATGGATTAATTTACTGTACCCACGCCACAGGATTCTCGTTTAATCCACAAACGGCAGATGCGGGGA
CCAGTATGAACGTGATCACTGAGCAAATTTATAATAAACTTTTTGAAACAAGTGATAACAGTGCAACGGTTATCCCTTCA
CTGGCGGAATCTTACCGTGTTTCAGATAACGGCACACTGATTACGATTAACTTGCGTAAAGGCGTGAAATTTCATCATAC
AGAATGGTTCACGCCAACCCGTGACTTTAATGCGGATGATGTCGTCTTTTCCATTAACAGAATGTTAGGCTATAACAGCT
ATCTACCCACATTAGATGATGAATCTATCCACTACAGCAATCCCCAATACCGTATTTTCCATAAGCAAGCAAAAAAGATC
CGCTTTCCTTATTTTGAAAGTATCAAATTAAATCAAAAAATTAAATCAATTAAAGCGATCACCCCCTACCAAGTACAGAT
AAAATTATTCCAAGCCGATGCGTCGATTTTGTCACACCTTGCTAGCCAATATGCCATTATTTTTTCGCAAGAATATGCCT
TACAGCTCAATGCAGACGATAACTTAGTACAATTAGACTTGTTACCTGTTGGTACAGGACCTTACAAAGTACAAAACTAT
TTCCGCAATCAATATGTCAGATTTATACGCAATGAGCATTATTGGAAAAAACCAGCCCAAATCAAAAATATCATTATTGA
TCTTTCAACCGACCGTACTGGACGCTTAGTGAAATTTCTCAATGGTGAATGTCAAATTGTCTCCTATCCAGAAGTCAGTC
AACTCGGGCTATTACAAGACAAAAACGAACATTTTTATGTGGATTTTGTGGAAGGCATGAATTTGTCTTACTTGGCGTTT
AATTTCAAAAAACCGGCGATGAAAAGTATGAAACTACGCCGAGCGATTTCTCAAGCCATTGATCGTCACCGTATTGTGCA
GACCATTTATCATCATACTGCAACTGTAGCAAATAATATTATTCCTAGTATTTCATGGGCTTCAAAAGTCAATACTCCAG
ACTTTGCTTACGATTATGCTCCAGAAAAAGCCCGTGCATTTTTACAAGATAAGCAACTACAGTTGACCATGTGGGTGATT
AATGAAGAACAAGTCTATAATCCTTCCCCATTAAAAATGGCGGAATTGATCAAACGAGATTTAGCCAATGTTGGTGTGAA
AGTGATTGTCCAGCCTGTAACACGTACGTATCTCATTGAACGTTTAAAAGCCCATTCCGAAGATTACGATATGATTTTAG
CAGGCTGGCTAGCGGGTAATCTTGACCCTGACAGTTTTATGCGTCCGATTCTCAGTTGTAACACCGTGACAGAAATTACG
AATTTTTCTAATTGGTGCGATCCCCTTTTCGATCATTTTATGGATAACGCTCTCAATACGACCAATTTACACTTACGTGC
CAGTGAATACAATTTAGCGCAAGAACTTATTTTATCTGAAGTCCCACTCATTCCTATCGCCAATGCGAAACGGATGTTGG
TGGTTAGCCCAAATGTGCAAGGCGTGAAAATGAGTCCATTTGGCAGTATTAATTTTGAAAACTTATCTTTACGTAAAGGA
GCAAAACCATGA

Upstream 100 bases:

>100_bases
TAATCGGATTTATTCAAGATCAGTCGTAAGCCAAAAAGGATAGCTTATCCCTGCAATATATTTTACAATTCCCCGATAAT
TTATCACAAATACACCAATT

Downstream 100 bases:

>100_bases
TCGTTGCTTTATTACGCCAAGTTTTCCTTGTGTTTCTGACATTACTGATTCTGTCTTTGCTCAGTTATATGATTTTAATC
CAAGACCCGCTGAATGAAGA

Product: SapA

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MLIRKVIFACFLFLYSHFVTAAPRVPNELTQNGLIYCTHATGFSFNPQTADAGTSMNVITEQIYNKLFETSDNSATVIPS
LAESYRVSDNGTLITINLRKGVKFHHTEWFTPTRDFNADDVVFSINRMLGYNSYLPTLDDESIHYSNPQYRIFHKQAKKI
RFPYFESIKLNQKIKSIKAITPYQVQIKLFQADASILSHLASQYAIIFSQEYALQLNADDNLVQLDLLPVGTGPYKVQNY
FRNQYVRFIRNEHYWKKPAQIKNIIIDLSTDRTGRLVKFLNGECQIVSYPEVSQLGLLQDKNEHFYVDFVEGMNLSYLAF
NFKKPAMKSMKLRRAISQAIDRHRIVQTIYHHTATVANNIIPSISWASKVNTPDFAYDYAPEKARAFLQDKQLQLTMWVI
NEEQVYNPSPLKMAELIKRDLANVGVKVIVQPVTRTYLIERLKAHSEDYDMILAGWLAGNLDPDSFMRPILSCNTVTEIT
NFSNWCDPLFDHFMDNALNTTNLHLRASEYNLAQELILSEVPLIPIANAKRMLVVSPNVQGVKMSPFGSINFENLSLRKG
AKP

Sequences:

>Translated_563_residues
MLIRKVIFACFLFLYSHFVTAAPRVPNELTQNGLIYCTHATGFSFNPQTADAGTSMNVITEQIYNKLFETSDNSATVIPS
LAESYRVSDNGTLITINLRKGVKFHHTEWFTPTRDFNADDVVFSINRMLGYNSYLPTLDDESIHYSNPQYRIFHKQAKKI
RFPYFESIKLNQKIKSIKAITPYQVQIKLFQADASILSHLASQYAIIFSQEYALQLNADDNLVQLDLLPVGTGPYKVQNY
FRNQYVRFIRNEHYWKKPAQIKNIIIDLSTDRTGRLVKFLNGECQIVSYPEVSQLGLLQDKNEHFYVDFVEGMNLSYLAF
NFKKPAMKSMKLRRAISQAIDRHRIVQTIYHHTATVANNIIPSISWASKVNTPDFAYDYAPEKARAFLQDKQLQLTMWVI
NEEQVYNPSPLKMAELIKRDLANVGVKVIVQPVTRTYLIERLKAHSEDYDMILAGWLAGNLDPDSFMRPILSCNTVTEIT
NFSNWCDPLFDHFMDNALNTTNLHLRASEYNLAQELILSEVPLIPIANAKRMLVVSPNVQGVKMSPFGSINFENLSLRKG
AKP
>Mature_563_residues
MLIRKVIFACFLFLYSHFVTAAPRVPNELTQNGLIYCTHATGFSFNPQTADAGTSMNVITEQIYNKLFETSDNSATVIPS
LAESYRVSDNGTLITINLRKGVKFHHTEWFTPTRDFNADDVVFSINRMLGYNSYLPTLDDESIHYSNPQYRIFHKQAKKI
RFPYFESIKLNQKIKSIKAITPYQVQIKLFQADASILSHLASQYAIIFSQEYALQLNADDNLVQLDLLPVGTGPYKVQNY
FRNQYVRFIRNEHYWKKPAQIKNIIIDLSTDRTGRLVKFLNGECQIVSYPEVSQLGLLQDKNEHFYVDFVEGMNLSYLAF
NFKKPAMKSMKLRRAISQAIDRHRIVQTIYHHTATVANNIIPSISWASKVNTPDFAYDYAPEKARAFLQDKQLQLTMWVI
NEEQVYNPSPLKMAELIKRDLANVGVKVIVQPVTRTYLIERLKAHSEDYDMILAGWLAGNLDPDSFMRPILSCNTVTEIT
NFSNWCDPLFDHFMDNALNTTNLHLRASEYNLAQELILSEVPLIPIANAKRMLVVSPNVQGVKMSPFGSINFENLSLRKG
AKP

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787551, Length=568, Percent_Identity=36.443661971831, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI1789966, Length=532, Percent_Identity=31.5789473684211, Blast_Score=303, Evalue=3e-83,
Organism=Escherichia coli, GI1787052, Length=514, Percent_Identity=24.9027237354086, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789887, Length=518, Percent_Identity=24.5173745173745, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1787762, Length=545, Percent_Identity=21.8348623853211, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87081878, Length=514, Percent_Identity=21.2062256809339, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787495, Length=326, Percent_Identity=21.7791411042945, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 64533; Mature: 64533

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIRKVIFACFLFLYSHFVTAAPRVPNELTQNGLIYCTHATGFSFNPQTADAGTSMNVIT
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHH
EQIYNKLFETSDNSATVIPSLAESYRVSDNGTLITINLRKGVKFHHTEWFTPTRDFNADD
HHHHHHHHHCCCCCEEEEHHHHHHEEECCCCEEEEEEECCCCEEECCCCCCCCCCCCCCH
VVFSINRMLGYNSYLPTLDDESIHYSNPQYRIFHKQAKKIRFPYFESIKLNQKIKSIKAI
HEEEHHHHHCCCCCCCCCCCCCEECCCCCEEEEEHHHHHCCCCCHHCEEHHHHHHHHHCC
TPYQVQIKLFQADASILSHLASQYAIIFSQEYALQLNADDNLVQLDLLPVGTGPYKVQNY
CCEEEEEEEEECCHHHHHHHHHHEEEEEEEEEEEEECCCCCEEEEEEEECCCCCHHHHHH
FRNQYVRFIRNEHYWKKPAQIKNIIIDLSTDRTGRLVKFLNGECQIVSYPEVSQLGLLQD
HHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHCCCCCEEEEECCCHHHCCCEEC
KNEHFYVDFVEGMNLSYLAFNFKKPAMKSMKLRRAISQAIDRHRIVQTIYHHTATVANNI
CCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPSISWASKVNTPDFAYDYAPEKARAFLQDKQLQLTMWVINEEQVYNPSPLKMAELIKRD
CCCCCHHHCCCCCCCEECCCCHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHH
LANVGVKVIVQPVTRTYLIERLKAHSEDYDMILAGWLAGNLDPDSFMRPILSCNTVTEIT
HHHCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCCCHHHHHHHHHCCCHHHHHH
NFSNWCDPLFDHFMDNALNTTNLHLRASEYNLAQELILSEVPLIPIANAKRMLVVSPNVQ
CCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCC
GVKMSPFGSINFENLSLRKGAKP
EEEECCCCCCCCCCEECCCCCCC
>Mature Secondary Structure
MLIRKVIFACFLFLYSHFVTAAPRVPNELTQNGLIYCTHATGFSFNPQTADAGTSMNVIT
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHH
EQIYNKLFETSDNSATVIPSLAESYRVSDNGTLITINLRKGVKFHHTEWFTPTRDFNADD
HHHHHHHHHCCCCCEEEEHHHHHHEEECCCCEEEEEEECCCCEEECCCCCCCCCCCCCCH
VVFSINRMLGYNSYLPTLDDESIHYSNPQYRIFHKQAKKIRFPYFESIKLNQKIKSIKAI
HEEEHHHHHCCCCCCCCCCCCCEECCCCCEEEEEHHHHHCCCCCHHCEEHHHHHHHHHCC
TPYQVQIKLFQADASILSHLASQYAIIFSQEYALQLNADDNLVQLDLLPVGTGPYKVQNY
CCEEEEEEEEECCHHHHHHHHHHEEEEEEEEEEEEECCCCCEEEEEEEECCCCCHHHHHH
FRNQYVRFIRNEHYWKKPAQIKNIIIDLSTDRTGRLVKFLNGECQIVSYPEVSQLGLLQD
HHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHCCCCCEEEEECCCHHHCCCEEC
KNEHFYVDFVEGMNLSYLAFNFKKPAMKSMKLRRAISQAIDRHRIVQTIYHHTATVANNI
CCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPSISWASKVNTPDFAYDYAPEKARAFLQDKQLQLTMWVINEEQVYNPSPLKMAELIKRD
CCCCCHHHCCCCCCCEECCCCHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHH
LANVGVKVIVQPVTRTYLIERLKAHSEDYDMILAGWLAGNLDPDSFMRPILSCNTVTEIT
HHHCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCCCHHHHHHHHHCCCHHHHHH
NFSNWCDPLFDHFMDNALNTTNLHLRASEYNLAQELILSEVPLIPIANAKRMLVVSPNVQ
CCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCC
GVKMSPFGSINFENLSLRKGAKP
EEEECCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]