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The map label for this gene is argA

Identifier: 15602693

GI number: 15602693

Start: 977194

End: 978516

Strand: Direct

Name: argA

Synonym: PM0828

Alternate gene names: 15602693

Gene position: 977194-978516 (Clockwise)

Preceding gene: 15602692

Following gene: 15602700

Centisome position: 43.29

GC content: 39.61

Gene sequence:

>1323_bases
ATGCGCAGTACAGAATTAGTTCATTGGTTTAGACAATCAACCCCTTATGTCAATATGCATAGAGGCAAAACTTTTGTCAT
TATGCTTGATGGGGACACTATTGCTTGTCCAAATTTTGTTAATATTATCAATGATATCAGCCTGCTACATAGTTTAGGCA
TTAAGTTAGTTTTAGTGTTTGGTGCACGTTATCAAATCAATGAGCTGTTACAGCAACATCAGATTGAATCGGTCTATCAT
AAAAATATTCGTATTACTGACTTAACAAGTTTAGAACTGGTGAAACAAGCTGTGGGTAAGCTCAATTACGATATTGCTTC
ACGCTTGTCACTACGTCTCCCTCATTCTCCTTTAATTGATGTGGTCAGCGGTAACTTCGTATTAGCCCAACCTATTGGCG
TAGATGACGGCATCGATTATCAATTAAGTGGCAAAATTCGCCGTATTAATACAGAAAGTATCCAGCAACAATTAGATCGT
GATGCGATTGTCTTAATTGGACCAATTGCACCTTCTGTTACTGGAGAAAGCTTTAATTTGCCTTTCGAAGAAATTGCTTC
ACAGCTTGCCATTAAGTTAAAAGCTGAAAAATTGATAGGCTTTTCCGCAACACAAGGCATCTTAGATGAAAACAACCAAA
CAATCAGTGATCTGTTGCCGCAAGATGCCGAGCTTTACTTAGCTAAACTGATACAACAAAACCAATATCACAGCTCTCAA
GCTCGCTTTTTACAAGCAGCTATTGAGGCTTGCCGATTTGGCATAAAGCGTTCACATTTGATCAGTTATGAAGAAGATGG
CTCACTGTTGCAGGAATTATTTACGCGTGACGGGGTTGGTACTCAGCTATCCATGGAACATTCCGAAACCATTCGCTTAG
CGACGGTCAGTGATATTCCCGCGTTACTCGAATTGATTCGTCCACTTGAACAGCAAGGAATTTTAGTCAAACGCTCACGC
GAACAATTAGAAATGGAAATTAACCAATATACGATTATCGATCGCGATGGTGTGATTATTGCTTGTGCTGCCTTAAATTG
CTATGCCGATGAGAAAATGGCAGAAATGGCTTGTGTGGCGGTTCACCCAGATTACCGTAATTCTTCGCGTGGCGATATTT
TATTAGAAGCTATCCAAAAACGCGCTAAACAACTGGGAATTGAAAAGCTGTTTGTTCTCACAACGCGTACAGTACATTGG
TTCCAAGAAAGAGGTTTTCAACTCGCAGAGATCGCAGATTTACCAGACAAAAAACGTCAACACTATAATTATCAACGTCG
TTCCAAAATCTTGATTCAAGCGCTACAAAATAAAAAAGGCTAA

Upstream 100 bases:

>100_bases
ACACCTCATCGCATTTTTTATTGCACCAAAATTCTGCTTGCATAAGATAATAAATGAATATAAATTCAGTAAAAATGAAT
AAGTATTAAAGGAGTTACCG

Downstream 100 bases:

>100_bases
CTACGTTAGCCTTTTTCTCTTTTCGCTTTTTTACTTAAGGCAGTGCAGAAATGACACAATAGCCCTCTTCCAAACCTGTG
ATTTGATAGCTAGTTTCACT

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MRSTELVHWFRQSTPYVNMHRGKTFVIMLDGDTIACPNFVNIINDISLLHSLGIKLVLVFGARYQINELLQQHQIESVYH
KNIRITDLTSLELVKQAVGKLNYDIASRLSLRLPHSPLIDVVSGNFVLAQPIGVDDGIDYQLSGKIRRINTESIQQQLDR
DAIVLIGPIAPSVTGESFNLPFEEIASQLAIKLKAEKLIGFSATQGILDENNQTISDLLPQDAELYLAKLIQQNQYHSSQ
ARFLQAAIEACRFGIKRSHLISYEEDGSLLQELFTRDGVGTQLSMEHSETIRLATVSDIPALLELIRPLEQQGILVKRSR
EQLEMEINQYTIIDRDGVIIACAALNCYADEKMAEMACVAVHPDYRNSSRGDILLEAIQKRAKQLGIEKLFVLTTRTVHW
FQERGFQLAEIADLPDKKRQHYNYQRRSKILIQALQNKKG

Sequences:

>Translated_440_residues
MRSTELVHWFRQSTPYVNMHRGKTFVIMLDGDTIACPNFVNIINDISLLHSLGIKLVLVFGARYQINELLQQHQIESVYH
KNIRITDLTSLELVKQAVGKLNYDIASRLSLRLPHSPLIDVVSGNFVLAQPIGVDDGIDYQLSGKIRRINTESIQQQLDR
DAIVLIGPIAPSVTGESFNLPFEEIASQLAIKLKAEKLIGFSATQGILDENNQTISDLLPQDAELYLAKLIQQNQYHSSQ
ARFLQAAIEACRFGIKRSHLISYEEDGSLLQELFTRDGVGTQLSMEHSETIRLATVSDIPALLELIRPLEQQGILVKRSR
EQLEMEINQYTIIDRDGVIIACAALNCYADEKMAEMACVAVHPDYRNSSRGDILLEAIQKRAKQLGIEKLFVLTTRTVHW
FQERGFQLAEIADLPDKKRQHYNYQRRSKILIQALQNKKG
>Mature_440_residues
MRSTELVHWFRQSTPYVNMHRGKTFVIMLDGDTIACPNFVNIINDISLLHSLGIKLVLVFGARYQINELLQQHQIESVYH
KNIRITDLTSLELVKQAVGKLNYDIASRLSLRLPHSPLIDVVSGNFVLAQPIGVDDGIDYQLSGKIRRINTESIQQQLDR
DAIVLIGPIAPSVTGESFNLPFEEIASQLAIKLKAEKLIGFSATQGILDENNQTISDLLPQDAELYLAKLIQQNQYHSSQ
ARFLQAAIEACRFGIKRSHLISYEEDGSLLQELFTRDGVGTQLSMEHSETIRLATVSDIPALLELIRPLEQQGILVKRSR
EQLEMEINQYTIIDRDGVIIACAALNCYADEKMAEMACVAVHPDYRNSSRGDILLEAIQKRAKQLGIEKLFVLTTRTVHW
FQERGFQLAEIADLPDKKRQHYNYQRRSKILIQALQNKKG

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain

Homologues:

Organism=Escherichia coli, GI1789181, Length=438, Percent_Identity=61.4155251141553, Blast_Score=563, Evalue=1e-162,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGA_PASMU (Q9CMJ6)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245765.1
- ProteinModelPortal:   Q9CMJ6
- SMR:   Q9CMJ6
- GeneID:   1244175
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0828
- NMPDR:   fig|272843.1.peg.828
- HOGENOM:   HBG545264
- OMA:   APYIHAF
- ProtClustDB:   PRK05279
- BioCyc:   PMUL272843:PM0828-MONOMER
- BRENDA:   2.3.1.1
- GO:   GO:0005737
- HAMAP:   MF_01105
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167
- Gene3D:   G3DSA:3.40.1160.10
- Gene3D:   G3DSA:3.40.630.30
- PIRSF:   PIRSF000423
- TIGRFAMs:   TIGR01890

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1; SSF53633 Aa_kinase; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.1.1

Molecular weight: Translated: 49842; Mature: 49842

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS51186 GNAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTELVHWFRQSTPYVNMHRGKTFVIMLDGDTIACPNFVNIINDISLLHSLGIKLVLVF
CCCHHHHHHHHHCCCEEEEECCCEEEEEECCCEEECCHHHHHHHHHHHHHHCCHHEEEEC
GARYQINELLQQHQIESVYHKNIRITDLTSLELVKQAVGKLNYDIASRLSLRLPHSPLID
CCHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHCCCCHHHHHEEECCCCCCHH
VVSGNFVLAQPIGVDDGIDYQLSGKIRRINTESIQQQLDRDAIVLIGPIAPSVTGESFNL
EECCCEEEEECCCCCCCCCEEECCCEEECCHHHHHHHHCCCEEEEEECCCCCCCCCCCCC
PFEEIASQLAIKLKAEKLIGFSATQGILDENNQTISDLLPQDAELYLAKLIQQNQYHSSQ
CHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCHHH
ARFLQAAIEACRFGIKRSHLISYEEDGSLLQELFTRDGVGTQLSMEHSETIRLATVSDIP
HHHHHHHHHHHHHCCCHHHEECCCCCHHHHHHHHHCCCCCCEEECCCCCEEEEEEHHHHH
ALLELIRPLEQQGILVKRSREQLEMEINQYTIIDRDGVIIACAALNCYADEKMAEMACVA
HHHHHHHHHHHCCEEEECCHHHHHEECCEEEEEECCCEEEEEEEHHHHHHHHHHHEEEEE
VHPDYRNSSRGDILLEAIQKRAKQLGIEKLFVLTTRTVHWFQERGFQLAEIADLPDKKRQ
ECCCCCCCCCCHHHHHHHHHHHHHHCHHHEEEHHHHHHHHHHHCCCEEEHHHCCCHHHHH
HYNYQRRSKILIQALQNKKG
HCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRSTELVHWFRQSTPYVNMHRGKTFVIMLDGDTIACPNFVNIINDISLLHSLGIKLVLVF
CCCHHHHHHHHHCCCEEEEECCCEEEEEECCCEEECCHHHHHHHHHHHHHHCCHHEEEEC
GARYQINELLQQHQIESVYHKNIRITDLTSLELVKQAVGKLNYDIASRLSLRLPHSPLID
CCHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHCCCCHHHHHEEECCCCCCHH
VVSGNFVLAQPIGVDDGIDYQLSGKIRRINTESIQQQLDRDAIVLIGPIAPSVTGESFNL
EECCCEEEEECCCCCCCCCEEECCCEEECCHHHHHHHHCCCEEEEEECCCCCCCCCCCCC
PFEEIASQLAIKLKAEKLIGFSATQGILDENNQTISDLLPQDAELYLAKLIQQNQYHSSQ
CHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCHHH
ARFLQAAIEACRFGIKRSHLISYEEDGSLLQELFTRDGVGTQLSMEHSETIRLATVSDIP
HHHHHHHHHHHHHCCCHHHEECCCCCHHHHHHHHHCCCCCCEEECCCCCEEEEEEHHHHH
ALLELIRPLEQQGILVKRSREQLEMEINQYTIIDRDGVIIACAALNCYADEKMAEMACVA
HHHHHHHHHHHCCEEEECCHHHHHEECCEEEEEECCCEEEEEEEHHHHHHHHHHHEEEEE
VHPDYRNSSRGDILLEAIQKRAKQLGIEKLFVLTTRTVHWFQERGFQLAEIADLPDKKRQ
ECCCCCCCCCCHHHHHHHHHHHHHHCHHHEEEHHHHHHHHHHHCCCEEEHHHCCCHHHHH
HYNYQRRSKILIQALQNKKG
HCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100