Click here to switch to the map view.

The map label for this gene is gntR [H]

Identifier: 15602656

GI number: 15602656

Start: 935538

End: 936536

Strand: Direct

Name: gntR [H]

Synonym: PM0791

Alternate gene names: 15602656

Gene position: 935538-936536 (Clockwise)

Preceding gene: 15602654

Following gene: 15602658

Centisome position: 41.44

GC content: 41.84

Gene sequence:

>999_bases
ATGATCAAGCGTAAACGTCCTACTTTGCAAGATATTGCTACACATCTCGGCATCACCAAAATGACCATTAGTCGCTATTT
ACGCCACCCTGATTCTGTCGCACCAGAAACACAAGCCAAAATTGCACAAGCTATCGAACACTTTGGCTATATTCCTAATC
GGGCACCAGATATTTTGTCAAACGCCAAAAGTCGAGCAATTGGGGTTTTAGTTCCCTCTTTAACTAATCAAGTGTTTGCT
GATGTGATCAAAGGGATTGAGCTAGTCAGTGATAAAGCAGGTTATCAAACTATGCTAGCCCACTATGGCTATAGTATGGA
AAAAGAAGAGCAACGCATTGAAAGCCTGCTTTCTTATCATGTTGATGGTTTGATCTTATCGGAAAATCAGCATTCTGAAC
GAACCTTGAAAATGCTTGAGGTCGCCAATATTCCTGTGGTCGAAATTATGGAATGCAGTGAAGTCGGTATTCAACAAGCC
ATTGGGTTTGATAATATTGCCGCCGCCCAAGCTATGGTGGAAACCATGATTCACCGTGGGCATAAAAATGTGGTGTATTT
TTCAGCACGTATGGATAAACGCACCTGTTTAAAAATGCAAGGCTATGAGCAAGCGATGAAAAAACATGGTTTACAACCTT
ATAGTTTAACCACTGAACAGCCTTCTTCTTTTAGTCTTGGTGCACAACAATTACATGATGCCCTACAACAACGTCCGAAT
TTAGACGGTATTTTTTGTACTAATGATGACTTAGCCATCGGCGCGTTATTTGAATGCCAACGGCGAGGGATCAAGGTGCC
AAAACAAATTGCCATTGCAGGTTTTCACGGACATGATGTGGGGCAATCTATGACACCACAGCTAGCTACCGTGATCACCC
CAAGATTAGAGATTGGTAAAATTGCGACACAGGAATTACTCAATCGTATTCACGGTATGCCACAACAAAGCGCGATCATC
AATTTAGGCTACCAAATTCATCTCGGTGAAAGTATCTAA

Upstream 100 bases:

>100_bases
CGGTAAGATTTTGCTCAATTTTGGCTTGCATTTTCAGATCTCCTAACCAATAATCTAGTTTGATTATACGTCAGTTAAAG
AAAAAAGACATTGAGAAAAC

Downstream 100 bases:

>100_bases
AAAAACGACCGCACTTTCCTCACGAGGACAAAAGTGCGGTTAACAGAACAGGCTTTTAATTAGAGTAAGGGTTTTAATGC
CTTGATACAACGTTCCACGA

Product: hypothetical protein

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MIKRKRPTLQDIATHLGITKMTISRYLRHPDSVAPETQAKIAQAIEHFGYIPNRAPDILSNAKSRAIGVLVPSLTNQVFA
DVIKGIELVSDKAGYQTMLAHYGYSMEKEEQRIESLLSYHVDGLILSENQHSERTLKMLEVANIPVVEIMECSEVGIQQA
IGFDNIAAAQAMVETMIHRGHKNVVYFSARMDKRTCLKMQGYEQAMKKHGLQPYSLTTEQPSSFSLGAQQLHDALQQRPN
LDGIFCTNDDLAIGALFECQRRGIKVPKQIAIAGFHGHDVGQSMTPQLATVITPRLEIGKIATQELLNRIHGMPQQSAII
NLGYQIHLGESI

Sequences:

>Translated_332_residues
MIKRKRPTLQDIATHLGITKMTISRYLRHPDSVAPETQAKIAQAIEHFGYIPNRAPDILSNAKSRAIGVLVPSLTNQVFA
DVIKGIELVSDKAGYQTMLAHYGYSMEKEEQRIESLLSYHVDGLILSENQHSERTLKMLEVANIPVVEIMECSEVGIQQA
IGFDNIAAAQAMVETMIHRGHKNVVYFSARMDKRTCLKMQGYEQAMKKHGLQPYSLTTEQPSSFSLGAQQLHDALQQRPN
LDGIFCTNDDLAIGALFECQRRGIKVPKQIAIAGFHGHDVGQSMTPQLATVITPRLEIGKIATQELLNRIHGMPQQSAII
NLGYQIHLGESI
>Mature_332_residues
MIKRKRPTLQDIATHLGITKMTISRYLRHPDSVAPETQAKIAQAIEHFGYIPNRAPDILSNAKSRAIGVLVPSLTNQVFA
DVIKGIELVSDKAGYQTMLAHYGYSMEKEEQRIESLLSYHVDGLILSENQHSERTLKMLEVANIPVVEIMECSEVGIQQA
IGFDNIAAAQAMVETMIHRGHKNVVYFSARMDKRTCLKMQGYEQAMKKHGLQPYSLTTEQPSSFSLGAQQLHDALQQRPN
LDGIFCTNDDLAIGALFECQRRGIKVPKQIAIAGFHGHDVGQSMTPQLATVITPRLEIGKIATQELLNRIHGMPQQSAII
NLGYQIHLGESI

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=331, Percent_Identity=57.0996978851964, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1790715, Length=332, Percent_Identity=47.289156626506, Blast_Score=325, Evalue=2e-90,
Organism=Escherichia coli, GI1790369, Length=320, Percent_Identity=29.0625, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790194, Length=307, Percent_Identity=25.0814332247557, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789068, Length=316, Percent_Identity=25.6329113924051, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788474, Length=300, Percent_Identity=25.3333333333333, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787948, Length=309, Percent_Identity=25.8899676375405, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787906, Length=266, Percent_Identity=27.4436090225564, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787580, Length=321, Percent_Identity=25.2336448598131, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789202, Length=300, Percent_Identity=24.3333333333333, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786540, Length=311, Percent_Identity=22.8295819935691, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786268, Length=284, Percent_Identity=24.6478873239437, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36919; Mature: 36919

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKRKRPTLQDIATHLGITKMTISRYLRHPDSVAPETQAKIAQAIEHFGYIPNRAPDILS
CCCCCCCCHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHH
NAKSRAIGVLVPSLTNQVFADVIKGIELVSDKAGYQTMLAHYGYSMEKEEQRIESLLSYH
HHHHHEEEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
VDGLILSENQHSERTLKMLEVANIPVVEIMECSEVGIQQAIGFDNIAAAQAMVETMIHRG
HCCEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
HKNVVYFSARMDKRTCLKMQGYEQAMKKHGLQPYSLTTEQPSSFSLGAQQLHDALQQRPN
CCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHHHCCC
LDGIFCTNDDLAIGALFECQRRGIKVPKQIAIAGFHGHDVGQSMTPQLATVITPRLEIGK
CCEEEECCCCCHHHHHHHHHHCCCCCCHHHEEECCCCCCCCCCCCCHHHHHHCCCHHHHH
IATQELLNRIHGMPQQSAIINLGYQIHLGESI
HHHHHHHHHHCCCCCCHHEEECCEEEEECCCC
>Mature Secondary Structure
MIKRKRPTLQDIATHLGITKMTISRYLRHPDSVAPETQAKIAQAIEHFGYIPNRAPDILS
CCCCCCCCHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHH
NAKSRAIGVLVPSLTNQVFADVIKGIELVSDKAGYQTMLAHYGYSMEKEEQRIESLLSYH
HHHHHEEEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
VDGLILSENQHSERTLKMLEVANIPVVEIMECSEVGIQQAIGFDNIAAAQAMVETMIHRG
HCCEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
HKNVVYFSARMDKRTCLKMQGYEQAMKKHGLQPYSLTTEQPSSFSLGAQQLHDALQQRPN
CCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHHHCCC
LDGIFCTNDDLAIGALFECQRRGIKVPKQIAIAGFHGHDVGQSMTPQLATVITPRLEIGK
CCEEEECCCCCHHHHHHHHHHCCCCCCHHHEEECCCCCCCCCCCCCHHHHHHCCCHHHHH
IATQELLNRIHGMPQQSAIINLGYQIHLGESI
HHHHHHHHHHCCCCCCHHEEECCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]