Click here to switch to the map view.

The map label for this gene is rnd [H]

Identifier: 15602571

GI number: 15602571

Start: 823393

End: 824544

Strand: Reverse

Name: rnd [H]

Synonym: PM0706

Alternate gene names: 15602571

Gene position: 824544-823393 (Counterclockwise)

Preceding gene: 15602572

Following gene: 15602568

Centisome position: 36.52

GC content: 41.49

Gene sequence:

>1152_bases
ATGAACAGTCAACAAAAAGAAATAAAAAATAAACCGCACTTTCAAGTCATTACTTCTGATTTAGCGCTGGCAGAAATTTG
TTATTCTGCCCAACAAAAAGCCGTAATTGCACTCGATACCGAATTTGTTCGTATCAAAACACTCTATCCACAATTAGGGC
TTATTCAACTCTATGATGGGGAACGAGTCAGTTTAATTGATCCTACTACCATTCAAGATTTTTCACCGTTTATTGCGTTA
CTGGCGAATACGGCTGTGTTGAAAGTGCTTCATGCGTGCAGCGAAGATTTAGAGGTGTTCCAACATAGTTTTAACCAGCT
TCCTACGCCGATGCTAGATACACAAATCATGGCAAACTTTCTAGGTTTTCCAAATTCTACTGGTTTAGCGACGTTAGTTC
AGCATTATTTTCAACTTGAAATTGATAAAGGTGCCTCGCGCACGGATTGGTTAGCCCGTCCTTTATCGGACAACCAGTTA
ATTTATGCCGCAGCTGACGTGTGGTATTTATTACCGCTTTATCAACGCATGCAGGAGGCGTTAGCACAAACACGATGGCA
AGAGGCCGCGCAACAAGATTGTGAAGCGTTGTTGTTAAAACGTGAACAACATAAAGATCCGGAGCTGGCGTATTTGGGCA
TTCCTAATGCATGGCGCTTAACACCGAGTGAATTAATGCGTTTAAAACTGTTGGCGAAATGGCGTCAAGAGGAAGCGACG
AAACGGGATTTAGCCTTAAATTTTGTAGTAAGGGCAGAGCACTTATGGCAAGTGGCTAAACATAATCCAAAACATACGTC
AGAATTGCTCGCGTTAGGATTAAGTCATCATGAAGTGCGCATTCATGGCAAAAAAATATTGCATTTGATAGGACAACTTA
AACGCTTTGATGATGTGGATTATCCGATGCCGATCGTACGTATTGCGGATGACCCTCGTTATAAAAAAGCACTCAAAGGC
TTACAACAAAAGCTGAAAAGCATTGCGCCTCCTGATTTAGCTGCAGAAGTGATTGCCAGTAAGCGTGGTTTAGAAAACTT
AATGAAATGGTGTTGGTTAGACAATCAAGATCCAACTCAGTTACCAGAGCTATTGGTCGGTTGGCGACGTGAATTTGGCT
TAGTATTGTTAAATACACTCGCAAATGGATAG

Upstream 100 bases:

>100_bases
CCGTGTTTTACGTGATGAGGAGCTGGCAAAACGTCCAGCTGAATAAGTATTCATTTCATTTTATTAGGGGCGACATTTGC
CCCTAATTTGTCGTATTAAG

Downstream 100 bases:

>100_bases
CTAGATAGAAGACAAAATAAAACCGCACTTAAGTGAATAAAGTGCGGTTTTTTTGTGAATTGTTGTGTGAGGATTATTGT
GTTGCTTGAATTGCAGTTAA

Product: ribonuclease D

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MNSQQKEIKNKPHFQVITSDLALAEICYSAQQKAVIALDTEFVRIKTLYPQLGLIQLYDGERVSLIDPTTIQDFSPFIAL
LANTAVLKVLHACSEDLEVFQHSFNQLPTPMLDTQIMANFLGFPNSTGLATLVQHYFQLEIDKGASRTDWLARPLSDNQL
IYAAADVWYLLPLYQRMQEALAQTRWQEAAQQDCEALLLKREQHKDPELAYLGIPNAWRLTPSELMRLKLLAKWRQEEAT
KRDLALNFVVRAEHLWQVAKHNPKHTSELLALGLSHHEVRIHGKKILHLIGQLKRFDDVDYPMPIVRIADDPRYKKALKG
LQQKLKSIAPPDLAAEVIASKRGLENLMKWCWLDNQDPTQLPELLVGWRREFGLVLLNTLANG

Sequences:

>Translated_383_residues
MNSQQKEIKNKPHFQVITSDLALAEICYSAQQKAVIALDTEFVRIKTLYPQLGLIQLYDGERVSLIDPTTIQDFSPFIAL
LANTAVLKVLHACSEDLEVFQHSFNQLPTPMLDTQIMANFLGFPNSTGLATLVQHYFQLEIDKGASRTDWLARPLSDNQL
IYAAADVWYLLPLYQRMQEALAQTRWQEAAQQDCEALLLKREQHKDPELAYLGIPNAWRLTPSELMRLKLLAKWRQEEAT
KRDLALNFVVRAEHLWQVAKHNPKHTSELLALGLSHHEVRIHGKKILHLIGQLKRFDDVDYPMPIVRIADDPRYKKALKG
LQQKLKSIAPPDLAAEVIASKRGLENLMKWCWLDNQDPTQLPELLVGWRREFGLVLLNTLANG
>Mature_383_residues
MNSQQKEIKNKPHFQVITSDLALAEICYSAQQKAVIALDTEFVRIKTLYPQLGLIQLYDGERVSLIDPTTIQDFSPFIAL
LANTAVLKVLHACSEDLEVFQHSFNQLPTPMLDTQIMANFLGFPNSTGLATLVQHYFQLEIDKGASRTDWLARPLSDNQL
IYAAADVWYLLPLYQRMQEALAQTRWQEAAQQDCEALLLKREQHKDPELAYLGIPNAWRLTPSELMRLKLLAKWRQEEAT
KRDLALNFVVRAEHLWQVAKHNPKHTSELLALGLSHHEVRIHGKKILHLIGQLKRFDDVDYPMPIVRIADDPRYKKALKG
LQQKLKSIAPPDLAAEVIASKRGLENLMKWCWLDNQDPTQLPELLVGWRREFGLVLLNTLANG

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=362, Percent_Identity=46.4088397790055, Blast_Score=330, Evalue=1e-91,
Organism=Drosophila melanogaster, GI161078302, Length=250, Percent_Identity=26, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 43832; Mature: 43832

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQQKEIKNKPHFQVITSDLALAEICYSAQQKAVIALDTEFVRIKTLYPQLGLIQLYDG
CCCCHHHHCCCCCEEEHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCCEEEEECC
ERVSLIDPTTIQDFSPFIALLANTAVLKVLHACSEDLEVFQHSFNQLPTPMLDTQIMANF
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LGFPNSTGLATLVQHYFQLEIDKGASRTDWLARPLSDNQLIYAAADVWYLLPLYQRMQEA
HCCCCCCCHHHHHHHHHHEEECCCCCCHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHH
LAQTRWQEAAQQDCEALLLKREQHKDPELAYLGIPNAWRLTPSELMRLKLLAKWRQEEAT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
KRDLALNFVVRAEHLWQVAKHNPKHTSELLALGLSHHEVRIHGKKILHLIGQLKRFDDVD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCC
YPMPIVRIADDPRYKKALKGLQQKLKSIAPPDLAAEVIASKRGLENLMKWCWLDNQDPTQ
CCCCEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LPELLVGWRREFGLVLLNTLANG
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSQQKEIKNKPHFQVITSDLALAEICYSAQQKAVIALDTEFVRIKTLYPQLGLIQLYDG
CCCCHHHHCCCCCEEEHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCCEEEEECC
ERVSLIDPTTIQDFSPFIALLANTAVLKVLHACSEDLEVFQHSFNQLPTPMLDTQIMANF
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LGFPNSTGLATLVQHYFQLEIDKGASRTDWLARPLSDNQLIYAAADVWYLLPLYQRMQEA
HCCCCCCCHHHHHHHHHHEEECCCCCCHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHH
LAQTRWQEAAQQDCEALLLKREQHKDPELAYLGIPNAWRLTPSELMRLKLLAKWRQEEAT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
KRDLALNFVVRAEHLWQVAKHNPKHTSELLALGLSHHEVRIHGKKILHLIGQLKRFDDVD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCC
YPMPIVRIADDPRYKKALKGLQQKLKSIAPPDLAAEVIASKRGLENLMKWCWLDNQDPTQ
CCCCEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LPELLVGWRREFGLVLLNTLANG
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]