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The map label for this gene is fnr

Identifier: 15602533

GI number: 15602533

Start: 777159

End: 777980

Strand: Direct

Name: fnr

Synonym: PM0668

Alternate gene names: 15602533

Gene position: 777159-777980 (Clockwise)

Preceding gene: 15602532

Following gene: 15602534

Centisome position: 34.43

GC content: 36.25

Gene sequence:

>822_bases
ATGATATTATTTGAGATAGATCAATTTTACATTATTTTTGTTGTATTAATTAAGGTTTTATTTATGGACACTAAAATTGG
GCGCAAAGTGCAATCGGGTGGGTGCGCTATTCACTGTCAAGACTGTAGTATTAGTCAACTTTGTATTCCTTTCACACTTA
ATGAACAGGAACTTGATCAGCTTGACAATATTATTGAACGCAAAAAACCAATACAAAAGTCGCAAGTGCTGTTTAAAGCG
GGTGATCCATTAAATTCTCTCTATGCGATCCGCTCTGGTACGATTAAAACCTATACTATCAGTGAAACTGGAGAAGAACA
AATCACTTCATTTCAGTTACCAGGCGATCTTGTTGGCTTTGATGCAATCATGAATATGCAACATCCAAGTTTTGCTCAAG
CACTGGAAACCTCTATGGTGTGCGAAATCCCATTTGACATTTTAGATGACTTATCCGGAAAAATGCCAAAGCTTCGCCAA
CAAATTATGCGTTTGATGAGTAATGAGATTAAAAATGATCAAGAAATGATTTTATTACTGTCAAAAATGAATGCTGAAGA
ACGCTTAGCGGCATTTATTTATAACCTTTCTAGACGTTATTCTGCACGTGGTTTTTCTGCTCGCGAATTCCGTTTAACCA
TGACACGTGGCGATATTGGCAACTATTTAGGTTTGACCGTTGAAACCATTAGCCGTCTTTTAGGTCGCTTACAAAAAATG
GGGATTCTTTCTGTACAAGGAAAGTACATCACGATTAATGATATGGTCGCACTAATTGAGTTATCCGGAACAACAAAAAC
CAATATTAAAATGGGAATTTAA

Upstream 100 bases:

>100_bases
AGCATAATCAGGATTTGAATAAGTCGCTTTTTCGTTAACTTTTCTGCCGCCATTTTTCTCTCTCTTGCTTATATTTAACA
CTTCTTAATTGTAACATTTA

Downstream 100 bases:

>100_bases
CATTTGAGTGCAACGTTTTGTTGCACTCCTCTACTTTTTTACATACGCACCTTGTTATTTCAATAAATCTTTTCTATCCT
ATAGACAACCTAATTAACAA

Product: fumarate/nitrate reduction transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MILFEIDQFYIIFVVLIKVLFMDTKIGRKVQSGGCAIHCQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQVLFKA
GDPLNSLYAIRSGTIKTYTISETGEEQITSFQLPGDLVGFDAIMNMQHPSFAQALETSMVCEIPFDILDDLSGKMPKLRQ
QIMRLMSNEIKNDQEMILLLSKMNAEERLAAFIYNLSRRYSARGFSAREFRLTMTRGDIGNYLGLTVETISRLLGRLQKM
GILSVQGKYITINDMVALIELSGTTKTNIKMGI

Sequences:

>Translated_273_residues
MILFEIDQFYIIFVVLIKVLFMDTKIGRKVQSGGCAIHCQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQVLFKA
GDPLNSLYAIRSGTIKTYTISETGEEQITSFQLPGDLVGFDAIMNMQHPSFAQALETSMVCEIPFDILDDLSGKMPKLRQ
QIMRLMSNEIKNDQEMILLLSKMNAEERLAAFIYNLSRRYSARGFSAREFRLTMTRGDIGNYLGLTVETISRLLGRLQKM
GILSVQGKYITINDMVALIELSGTTKTNIKMGI
>Mature_273_residues
MILFEIDQFYIIFVVLIKVLFMDTKIGRKVQSGGCAIHCQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQVLFKA
GDPLNSLYAIRSGTIKTYTISETGEEQITSFQLPGDLVGFDAIMNMQHPSFAQALETSMVCEIPFDILDDLSGKMPKLRQ
QIMRLMSNEIKNDQEMILLLSKMNAEERLAAFIYNLSRRYSARGFSAREFRLTMTRGDIGNYLGLTVETISRLLGRLQKM
GILSVQGKYITINDMVALIELSGTTKTNIKMGI

Specific function: It is involved in the activation of genes necessary for anaerobic respiration

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1787595, Length=245, Percent_Identity=80, Blast_Score=409, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FNR_PASMU (Q9CMY2)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245605.1
- ProteinModelPortal:   Q9CMY2
- GeneID:   1244015
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0668
- NMPDR:   fig|272843.1.peg.668
- HOGENOM:   HBG753167
- OMA:   FSANQFR
- ProtClustDB:   PRK11161
- BioCyc:   PMUL272843:PM0668-MONOMER
- GO:   GO:0005737
- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991
- Gene3D:   G3DSA:2.60.120.10
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00034
- SMART:   SM00100
- SMART:   SM00419

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp; SSF51206 cNMP_binding

EC number: NA

Molecular weight: Translated: 30888; Mature: 30888

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS50042 CNMP_BINDING_3; PS00042 HTH_CRP_1; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILFEIDQFYIIFVVLIKVLFMDTKIGRKVQSGGCAIHCQDCSISQLCIPFTLNEQELDQ
CEEEEEHHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEECCCCCCCEEEEEECCHHHHHH
LDNIIERKKPIQKSQVLFKAGDPLNSLYAIRSGTIKTYTISETGEEQITSFQLPGDLVGF
HHHHHHHCCCCCHHHEEEECCCCHHHHHHEECCCEEEEEECCCCHHHHEEECCCCCHHHH
DAIMNMQHPSFAQALETSMVCEIPFDILDDLSGKMPKLRQQIMRLMSNEIKNDQEMILLL
HHHHCCCCCHHHHHHHHHHEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
SKMNAEERLAAFIYNLSRRYSARGFSAREFRLTMTRGDIGNYLGLTVETISRLLGRLQKM
HHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
GILSVQGKYITINDMVALIELSGTTKTNIKMGI
CEEEECCCEEEHHHEEEEEEECCCCCCCEEECC
>Mature Secondary Structure
MILFEIDQFYIIFVVLIKVLFMDTKIGRKVQSGGCAIHCQDCSISQLCIPFTLNEQELDQ
CEEEEEHHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEECCCCCCCEEEEEECCHHHHHH
LDNIIERKKPIQKSQVLFKAGDPLNSLYAIRSGTIKTYTISETGEEQITSFQLPGDLVGF
HHHHHHHCCCCCHHHEEEECCCCHHHHHHEECCCEEEEEECCCCHHHHEEECCCCCHHHH
DAIMNMQHPSFAQALETSMVCEIPFDILDDLSGKMPKLRQQIMRLMSNEIKNDQEMILLL
HHHHCCCCCHHHHHHHHHHEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
SKMNAEERLAAFIYNLSRRYSARGFSAREFRLTMTRGDIGNYLGLTVETISRLLGRLQKM
HHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
GILSVQGKYITINDMVALIELSGTTKTNIKMGI
CEEEECCCEEEHHHEEEEEEECCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100