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The map label for this gene is asnC [H]

Identifier: 15602508

GI number: 15602508

Start: 744470

End: 745885

Strand: Direct

Name: asnC [H]

Synonym: PM0643

Alternate gene names: 15602508

Gene position: 744470-745885 (Clockwise)

Preceding gene: 15602505

Following gene: 15602509

Centisome position: 32.98

GC content: 41.6

Gene sequence:

>1416_bases
TTGAGGTTTTATATGACTAAAGTCGCATCTATTGTAGATGTTTTACAAGGCAAAATTGCCATTGGTGAAACCGTCACTGT
CCGTGGCTGGATTCGTACTCGCCGTGACTCAAAAGCAGGTCTTTCTTTTTTGGCCATTTATGATGGTTCTTGCTTTGATC
CTATCCAAGCAATTGTCAATAATGATATTGAAAATTACGAAACAGAAGTGTTGCGTTTAACAACCGGCTGTTCTGTTATT
GTAACAGGTACTGTTGTAGAATCCCCTGCTGAAGGTCAAGCTGTTGAATTACAAGCAGAAAAAGTCGAGGTCGCAGGTTG
GGTTGAGGACCCAGAAACATATCCAATGGCGGCAAAACGTCACTCAATTGAATATTTACGTGAAGTGGCTCATTTACGCC
CTCGTACCAATATTATTGGCGCAGTCGCACGTGTTCGTCACTGCTTAGCACAAGCCATCCACCGTTTTTTCCATGAACAA
GGTTTCTATTGGGTAGCGACGCCATTAATTACCGCATCAGATACAGAAGGGGCAGGCGAAATGTTCCGTGTGTCCACTCT
CGACTTAGAAAATCTGCCACGTGATGACAAAGGTGCGGTCGATTTTTCACAAGATTTCTTTGGAAAAGAATCTTTCTTAA
CAGTATCCGGGCAATTAAATGGTGAAACCTATGCCTGTGCTTTAAGTAAAATTTATACTTTTGGTCCAACATTCCGTGCA
GAAAATTCCAATACAACACGCCACTTAGCTGAATTCTGGATGGTTGAACCAGAAATTGCCTTTGCGACTCTGGCCGATAA
CGCGAAATTAGCCGAGGATATGTTAAAGTATGTATTCCGTGCAGTACTTGAAGAACGCAAAGATGACTTAAAATTCTTTG
AAAAACATGTCGATAACGACGTTATTAGCCGTTTAGAAAATTTCATCAATTCAGATTTCGCGCAAATTGACTATACTGAT
GCAATTGAGGTGTTATTACAATCAGGTAAGAAATTTGAATTCCCAGTTTCTTGGGGGATCGACTTATCCTCTGAACATGA
ACGTTATTTAGCGGAAGAACACTTTAAATCGCCAGTTGTGGTTAAAAACTATCCGAAAGACATCAAGGCTTTCTATATGC
GCTTAAATGATGACGGAAAAACTGTCGCAGCAATGGATGTGTTAGCACCGGGTATTGGTGAAATTATCGGCGGTTCACAA
CGTGAAGAACGTTTAGACGTGCTGGATAAACGAATGATCGAAATGGGACTCAACCCAGAAGATTACTGGTGGTATCGCGA
TTTACGCCGTTATGGCACCGTACCACACGCTGGTTTTGGTTTAGGTTTTGAACGTTTAATCGTGTATGTTACTGGCGTAC
AAAATATTCGTGATGTGATCCCATTCCCACGTTCACCGCGTAATGCAAACTTCTAA

Upstream 100 bases:

>100_bases
GTCTATTTCACAAAAACAAAAAATTTAATAGATTTTGTGAATTCGACTAAGTTGAGGTAAACTATGTCGGTTTATTTCTT
CACAAAAAATTTGTTGAAAA

Downstream 100 bases:

>100_bases
ACAAACTTAACACTGCTAATTCCCCTTATATTATTAAGGGGAATTTTTTAGGTCACCTGAATGGCTCGCTTACGTAAAAA
CTGTATTTTATCGCTGCTTT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MRFYMTKVASIVDVLQGKIAIGETVTVRGWIRTRRDSKAGLSFLAIYDGSCFDPIQAIVNNDIENYETEVLRLTTGCSVI
VTGTVVESPAEGQAVELQAEKVEVAGWVEDPETYPMAAKRHSIEYLREVAHLRPRTNIIGAVARVRHCLAQAIHRFFHEQ
GFYWVATPLITASDTEGAGEMFRVSTLDLENLPRDDKGAVDFSQDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRA
ENSNTTRHLAEFWMVEPEIAFATLADNAKLAEDMLKYVFRAVLEERKDDLKFFEKHVDNDVISRLENFINSDFAQIDYTD
AIEVLLQSGKKFEFPVSWGIDLSSEHERYLAEEHFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQ
REERLDVLDKRMIEMGLNPEDYWWYRDLRRYGTVPHAGFGLGFERLIVYVTGVQNIRDVIPFPRSPRNANF

Sequences:

>Translated_471_residues
MRFYMTKVASIVDVLQGKIAIGETVTVRGWIRTRRDSKAGLSFLAIYDGSCFDPIQAIVNNDIENYETEVLRLTTGCSVI
VTGTVVESPAEGQAVELQAEKVEVAGWVEDPETYPMAAKRHSIEYLREVAHLRPRTNIIGAVARVRHCLAQAIHRFFHEQ
GFYWVATPLITASDTEGAGEMFRVSTLDLENLPRDDKGAVDFSQDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRA
ENSNTTRHLAEFWMVEPEIAFATLADNAKLAEDMLKYVFRAVLEERKDDLKFFEKHVDNDVISRLENFINSDFAQIDYTD
AIEVLLQSGKKFEFPVSWGIDLSSEHERYLAEEHFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQ
REERLDVLDKRMIEMGLNPEDYWWYRDLRRYGTVPHAGFGLGFERLIVYVTGVQNIRDVIPFPRSPRNANF
>Mature_471_residues
MRFYMTKVASIVDVLQGKIAIGETVTVRGWIRTRRDSKAGLSFLAIYDGSCFDPIQAIVNNDIENYETEVLRLTTGCSVI
VTGTVVESPAEGQAVELQAEKVEVAGWVEDPETYPMAAKRHSIEYLREVAHLRPRTNIIGAVARVRHCLAQAIHRFFHEQ
GFYWVATPLITASDTEGAGEMFRVSTLDLENLPRDDKGAVDFSQDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRA
ENSNTTRHLAEFWMVEPEIAFATLADNAKLAEDMLKYVFRAVLEERKDDLKFFEKHVDNDVISRLENFINSDFAQIDYTD
AIEVLLQSGKKFEFPVSWGIDLSSEHERYLAEEHFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQ
REERLDVLDKRMIEMGLNPEDYWWYRDLRRYGTVPHAGFGLGFERLIVYVTGVQNIRDVIPFPRSPRNANF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=464, Percent_Identity=43.5344827586207, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI4758762, Length=461, Percent_Identity=29.5010845986985, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI45439306, Length=343, Percent_Identity=27.6967930029155, Blast_Score=123, Evalue=4e-28,
Organism=Escherichia coli, GI1787161, Length=464, Percent_Identity=82.1120689655172, Blast_Score=824, Evalue=0.0,
Organism=Escherichia coli, GI1788173, Length=105, Percent_Identity=35.2380952380952, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71984122, Length=472, Percent_Identity=30.2966101694915, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17556372, Length=432, Percent_Identity=31.4814814814815, Blast_Score=191, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI17551876, Length=478, Percent_Identity=26.1506276150628, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319872, Length=472, Percent_Identity=36.228813559322, Blast_Score=288, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6321807, Length=461, Percent_Identity=30.58568329718, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6323011, Length=500, Percent_Identity=25.2, Blast_Score=120, Evalue=6e-28,
Organism=Drosophila melanogaster, GI19922416, Length=473, Percent_Identity=37.2093023255814, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI19921528, Length=469, Percent_Identity=29.2110874200426, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI17136276, Length=486, Percent_Identity=24.8971193415638, Blast_Score=105, Evalue=8e-23,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 53454; Mature: 53454

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFYMTKVASIVDVLQGKIAIGETVTVRGWIRTRRDSKAGLSFLAIYDGSCFDPIQAIVN
CCCHHHHHHHHHHHHHCCEEECCEEEEEHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHC
NDIENYETEVLRLTTGCSVIVTGTVVESPAEGQAVELQAEKVEVAGWVEDPETYPMAAKR
CCHHHHHHHEEEEECCCEEEEEEEEECCCCCCCEEEEEEEEEEEEEECCCCCCCCCHHHH
HSIEYLREVAHLRPRTNIIGAVARVRHCLAQAIHRFFHEQGFYWVATPLITASDTEGAGE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECEEEECCCCCCCC
MFRVSTLDLENLPRDDKGAVDFSQDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRA
EEEEEEECHHHCCCCCCCCCCCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEC
ENSNTTRHLAEFWMVEPEIAFATLADNAKLAEDMLKYVFRAVLEERKDDLKFFEKHVDND
CCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VISRLENFINSDFAQIDYTDAIEVLLQSGKKFEFPVSWGIDLSSEHERYLAEEHFKSPVV
HHHHHHHHHCCCHHHCCHHHHHHHHHHCCCCEECCEEECCCCCCHHHHHHHHHHCCCCEE
VKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDKRMIEMGLNPE
ECCCCHHHHHHEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
DYWWYRDLRRYGTVPHAGFGLGFERLIVYVTGVQNIRDVIPFPRSPRNANF
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRFYMTKVASIVDVLQGKIAIGETVTVRGWIRTRRDSKAGLSFLAIYDGSCFDPIQAIVN
CCCHHHHHHHHHHHHHCCEEECCEEEEEHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHC
NDIENYETEVLRLTTGCSVIVTGTVVESPAEGQAVELQAEKVEVAGWVEDPETYPMAAKR
CCHHHHHHHEEEEECCCEEEEEEEEECCCCCCCEEEEEEEEEEEEEECCCCCCCCCHHHH
HSIEYLREVAHLRPRTNIIGAVARVRHCLAQAIHRFFHEQGFYWVATPLITASDTEGAGE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECEEEECCCCCCCC
MFRVSTLDLENLPRDDKGAVDFSQDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRA
EEEEEEECHHHCCCCCCCCCCCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEC
ENSNTTRHLAEFWMVEPEIAFATLADNAKLAEDMLKYVFRAVLEERKDDLKFFEKHVDND
CCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VISRLENFINSDFAQIDYTDAIEVLLQSGKKFEFPVSWGIDLSSEHERYLAEEHFKSPVV
HHHHHHHHHCCCHHHCCHHHHHHHHHHCCCCEECCEEECCCCCCHHHHHHHHHHCCCCEE
VKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDKRMIEMGLNPE
ECCCCHHHHHHEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
DYWWYRDLRRYGTVPHAGFGLGFERLIVYVTGVQNIRDVIPFPRSPRNANF
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA