Click here to switch to the map view.

The map label for this gene is infC [H]

Identifier: 15602467

GI number: 15602467

Start: 699932

End: 700396

Strand: Direct

Name: infC [H]

Synonym: PM0602

Alternate gene names: 15602467

Gene position: 699932-700396 (Clockwise)

Preceding gene: 15602466

Following gene: 15602468

Centisome position: 31.0

GC content: 43.44

Gene sequence:

>465_bases
TTGATTGACCAAGATGGCGAACAAGCAGGTATTGTATCAATTCAACAAGCCTTAGAAATGGCTGAGCAAGCAGAATTAGA
TCTTGTTGAGATTAGTCCAAACGCAGAGCCACCAGTGTGTCGCATTATGAATTACGGTAAATTCCTATATGAAAAAGGAA
AAGCGGCAAAAGAGCAGAAGAAAAAACAAAAAGTTGTTCAAGTGAAGGAAATTAAATTCCGTCCGGGTACAGATGAAGGC
GACTATCAAGTGAAATTACGCAGCCTGATTCGTTTCTTGGAAGAGGGCGACAAAGCAAAAATTACTGTGCGTTTCCGTGG
ACGTGAGATGGCACACCAAGATATCGGGTTAGAAGTGTTAGAGCGCGTGAAAAACGATTTAGCTGAGATCTCCGTCGTTG
AGTCCGCCCCTGGCAGACTTGAAGGTAGACAGGCTGTTATGGTACTTGCCCCGAAAAAGAAATAG

Upstream 100 bases:

>100_bases
AAACTAATAGAGGAATACGACTATTAAAACCGTAAAAAAAGCACCCGTAGCTAACCGTCCGAATCGCATTAATGATGAGA
TTCGAGTAAAAGAAGTTCGT

Downstream 100 bases:

>100_bases
TTTTCTAAAAATGCAATCAAAATAACATTGATTGCATTTTTGCTTTTTACCACTTCTCTTTATATTTAAAGCATAATGAG
ATTTGCTGTTGTCACTTTGA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MIDQDGEQAGIVSIQQALEMAEQAELDLVEISPNAEPPVCRIMNYGKFLYEKGKAAKEQKKKQKVVQVKEIKFRPGTDEG
DYQVKLRSLIRFLEEGDKAKITVRFRGREMAHQDIGLEVLERVKNDLAEISVVESAPGRLEGRQAVMVLAPKKK

Sequences:

>Translated_154_residues
MIDQDGEQAGIVSIQQALEMAEQAELDLVEISPNAEPPVCRIMNYGKFLYEKGKAAKEQKKKQKVVQVKEIKFRPGTDEG
DYQVKLRSLIRFLEEGDKAKITVRFRGREMAHQDIGLEVLERVKNDLAEISVVESAPGRLEGRQAVMVLAPKKK
>Mature_154_residues
MIDQDGEQAGIVSIQQALEMAEQAELDLVEISPNAEPPVCRIMNYGKFLYEKGKAAKEQKKKQKVVQVKEIKFRPGTDEG
DYQVKLRSLIRFLEEGDKAKITVRFRGREMAHQDIGLEVLERVKNDLAEISVVESAPGRLEGRQAVMVLAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=150, Percent_Identity=81.3333333333333, Blast_Score=228, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 17379; Mature: 17379

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDQDGEQAGIVSIQQALEMAEQAELDLVEISPNAEPPVCRIMNYGKFLYEKGKAAKEQK
CCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHH
KKQKVVQVKEIKFRPGTDEGDYQVKLRSLIRFLEEGDKAKITVRFRGREMAHQDIGLEVL
HHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCHHHH
ERVKNDLAEISVVESAPGRLEGRQAVMVLAPKKK
HHHHHHHHHEEHHCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MIDQDGEQAGIVSIQQALEMAEQAELDLVEISPNAEPPVCRIMNYGKFLYEKGKAAKEQK
CCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHH
KKQKVVQVKEIKFRPGTDEGDYQVKLRSLIRFLEEGDKAKITVRFRGREMAHQDIGLEVL
HHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCHHHH
ERVKNDLAEISVVESAPGRLEGRQAVMVLAPKKK
HHHHHHHHHEEHHCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]