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The map label for this gene is can [H]

Identifier: 15602440

GI number: 15602440

Start: 662017

End: 662706

Strand: Reverse

Name: can [H]

Synonym: PM0575

Alternate gene names: 15602440

Gene position: 662706-662017 (Counterclockwise)

Preceding gene: 15602442

Following gene: 15602439

Centisome position: 29.36

GC content: 38.84

Gene sequence:

>690_bases
ATGAAAAAAATTGAACAACTTTTTGCCAATAATTATAGCTGGGCGTTACGGATGAAAGAGGAAAACTCCTCTTACTTTAA
AGAATTGGCTGATCATCAAACCCCGAGCTATCTTTGGATTGGTTGCTCGGATAGCCGTGTTCCTGCAGAAAAATTAACGA
ATTTAGGACCGGGTGAGCTGTTTGTACATCGTAATGTTGCAAATCAAGTCATTCACACCGATCTAAACTGTTTATCTGTT
GTGCAATATGCCGTTGAGGTCTTAAATATTGAACACATTATTATTTGTGGACATACAAACTGTGGTGGAATTAAAGCCGC
CATGGCGGATCAAGATTTAGGTTTAATTAATAACTGGTTACTCCACTTACGCGATATTTGGTATAAACACAGTCATTTAC
TTGGCAATTTACCGCCTGAAAAACGGGCTGATATGCTGACGAAAATTAACGTCGCAGAGCAAGTTTATAACTTAGGTCGC
TCGTCAATCATTAAATCCGCGTGGAAAAATGGGAAAAAACTCTCATTACATGGTTGGGTTTATGATGTCAATGACGGTTT
CTTAATCGATCAAGGTGTCATTGCTACTAGTCGAGAAAGCCTTGAAATCTCCTACCGCAATGCGATTGCCCGTCTTTTAA
AACTCAATGAAGATGAGATCTTGAAAAAAGATCAAGACGAAGAAGCGTAA

Upstream 100 bases:

>100_bases
AAAAACAAGTTATCCTATACAATTTTTTGCCTTTCTTTACCCACTGTCTATTTCTAAGCTATACTAGCCCCCTTATTTTT
GCGGTATAGGAATCACTCTA

Downstream 100 bases:

>100_bases
TTTCTCAAAAAGAAACAGCCGTGCCCTACGGGGTGGGTTGTTTTTTAAGCAAAACAAGACCGCTATTTTCCCCAACTAAT
TTTTGCTAGAATGCTAGCCA

Product: hypothetical protein

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKKIEQLFANNYSWALRMKEENSSYFKELADHQTPSYLWIGCSDSRVPAEKLTNLGPGELFVHRNVANQVIHTDLNCLSV
VQYAVEVLNIEHIIICGHTNCGGIKAAMADQDLGLINNWLLHLRDIWYKHSHLLGNLPPEKRADMLTKINVAEQVYNLGR
SSIIKSAWKNGKKLSLHGWVYDVNDGFLIDQGVIATSRESLEISYRNAIARLLKLNEDEILKKDQDEEA

Sequences:

>Translated_229_residues
MKKIEQLFANNYSWALRMKEENSSYFKELADHQTPSYLWIGCSDSRVPAEKLTNLGPGELFVHRNVANQVIHTDLNCLSV
VQYAVEVLNIEHIIICGHTNCGGIKAAMADQDLGLINNWLLHLRDIWYKHSHLLGNLPPEKRADMLTKINVAEQVYNLGR
SSIIKSAWKNGKKLSLHGWVYDVNDGFLIDQGVIATSRESLEISYRNAIARLLKLNEDEILKKDQDEEA
>Mature_229_residues
MKKIEQLFANNYSWALRMKEENSSYFKELADHQTPSYLWIGCSDSRVPAEKLTNLGPGELFVHRNVANQVIHTDLNCLSV
VQYAVEVLNIEHIIICGHTNCGGIKAAMADQDLGLINNWLLHLRDIWYKHSHLLGNLPPEKRADMLTKINVAEQVYNLGR
SSIIKSAWKNGKKLSLHGWVYDVNDGFLIDQGVIATSRESLEISYRNAIARLLKLNEDEILKKDQDEEA

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=212, Percent_Identity=63.2075471698113, Blast_Score=293, Evalue=5e-81,
Organism=Escherichia coli, GI1786534, Length=195, Percent_Identity=34.8717948717949, Blast_Score=102, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324292, Length=194, Percent_Identity=31.4432989690722, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 26070; Mature: 26070

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIEQLFANNYSWALRMKEENSSYFKELADHQTPSYLWIGCSDSRVPAEKLTNLGPGEL
CCHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCCCCE
FVHRNVANQVIHTDLNCLSVVQYAVEVLNIEHIIICGHTNCGGIKAAMADQDLGLINNWL
EEECCHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHCCCCHHHHHHHH
LHLRDIWYKHSHLLGNLPPEKRADMLTKINVAEQVYNLGRSSIIKSAWKNGKKLSLHGWV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEEE
YDVNDGFLIDQGVIATSRESLEISYRNAIARLLKLNEDEILKKDQDEEA
EECCCCEEEECCEEECCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
>Mature Secondary Structure
MKKIEQLFANNYSWALRMKEENSSYFKELADHQTPSYLWIGCSDSRVPAEKLTNLGPGEL
CCHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCCCCE
FVHRNVANQVIHTDLNCLSVVQYAVEVLNIEHIIICGHTNCGGIKAAMADQDLGLINNWL
EEECCHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHCCCCHHHHHHHH
LHLRDIWYKHSHLLGNLPPEKRADMLTKINVAEQVYNLGRSSIIKSAWKNGKKLSLHGWV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEEE
YDVNDGFLIDQGVIATSRESLEISYRNAIARLLKLNEDEILKKDQDEEA
EECCCCEEEECCEEECCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]