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The map label for this gene is trxB [H]

Identifier: 15602438

GI number: 15602438

Start: 659993

End: 660946

Strand: Reverse

Name: trxB [H]

Synonym: PM0573

Alternate gene names: 15602438

Gene position: 660946-659993 (Counterclockwise)

Preceding gene: 15602439

Following gene: 15602437

Centisome position: 29.28

GC content: 44.34

Gene sequence:

>954_bases
ATGAATGCAATGAAACACAGCCAACTTTTAATTTTAGGATCGGGACCTGCCGGTTATACCGCAGCCATTTATGCGGCACG
CGCGAACCTCAAACCGGTTTTAGTGACGGGTTTACAACAAGGTGGACAATTAACAACCACAACTGAAATTGAAAATTGGC
CGGGGGATTTTGGTGAAACAACAGGACCAGAATTAATGCAACGCATGTTACAACATGCTGAAAAATTTGACACGGAAATT
ATCTTTGACCATATCAATAAAGTGGATCTTTCCTCTCGCCCATTCAAATTATACGGTGATGTCCACACCTTCAGTTGTGA
TGCCTTAATTATCGCGACAGGGGCATCTGCGCGTTATTTAGGTTTGCCTTCTGAAGAAGCGTATAAAGGTCGTGGTGTGT
CTGCGTGTGCAACTTGTGATGGCTTTTTCTATCGTAATAAACCAGTGGCAGTCATCGGTGGCGGTAATACCGCAGTAGAA
GAAGCACTCTATCTCGCTAATATTGCTTCAGAAGTGCATTTAGTACACCGCCGTGACAGTTTCCGCAGTGAAAAAATTCT
AATTGACCGTTTAATGAAAAAAGTCGAAGAAGGCAAAATTATCCTCCATACTAACCGCACTTTAGATGAAGTATTGGGTG
ATAATATGGGCGTGACGGGTGTTCGCTTGAAAGATACACAATCTGAAGCCACAGAAGAACTCAGCCTAGACGGTGTCTTT
ATTGCGATTGGTCATGCACCAAATACGGATATTTTTGCGGAGCAACTTGAACTAAACAATGGCTATATTGTGGTCAAGTC
AGGCTTAGAAGGTAATGCCACTGCGACTTCAGTGGACGGAGTCTTTGCTGCGGGTGATGTGATGGATCATAACTACCGCC
AAGCGATTACCTCAGCGGGTACCGGTTGCATGGCTGCGCTTGACGCAGAACGCTATTTGGATGCCCAAAAATAA

Upstream 100 bases:

>100_bases
CTATTCTCTATTATATTAATAGGCAAGATTAGTGATAGATTGCCCTCTCTGAACGGTCTATAATACAAACAGAATTTTCG
TGATAGTAAAGGATAACAAT

Downstream 100 bases:

>100_bases
CATTTTATTGTTTTATATTATTCGTCCAATCTCGCCTTTGGGCGAATAATTTTTTTTCGCTTACGGAATCAATAATCGGA
CAGTTATGGAAAAATCTCGC

Product: hypothetical protein

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNAMKHSQLLILGSGPAGYTAAIYAARANLKPVLVTGLQQGGQLTTTTEIENWPGDFGETTGPELMQRMLQHAEKFDTEI
IFDHINKVDLSSRPFKLYGDVHTFSCDALIIATGASARYLGLPSEEAYKGRGVSACATCDGFFYRNKPVAVIGGGNTAVE
EALYLANIASEVHLVHRRDSFRSEKILIDRLMKKVEEGKIILHTNRTLDEVLGDNMGVTGVRLKDTQSEATEELSLDGVF
IAIGHAPNTDIFAEQLELNNGYIVVKSGLEGNATATSVDGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDAQK

Sequences:

>Translated_317_residues
MNAMKHSQLLILGSGPAGYTAAIYAARANLKPVLVTGLQQGGQLTTTTEIENWPGDFGETTGPELMQRMLQHAEKFDTEI
IFDHINKVDLSSRPFKLYGDVHTFSCDALIIATGASARYLGLPSEEAYKGRGVSACATCDGFFYRNKPVAVIGGGNTAVE
EALYLANIASEVHLVHRRDSFRSEKILIDRLMKKVEEGKIILHTNRTLDEVLGDNMGVTGVRLKDTQSEATEELSLDGVF
IAIGHAPNTDIFAEQLELNNGYIVVKSGLEGNATATSVDGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDAQK
>Mature_317_residues
MNAMKHSQLLILGSGPAGYTAAIYAARANLKPVLVTGLQQGGQLTTTTEIENWPGDFGETTGPELMQRMLQHAEKFDTEI
IFDHINKVDLSSRPFKLYGDVHTFSCDALIIATGASARYLGLPSEEAYKGRGVSACATCDGFFYRNKPVAVIGGGNTAVE
EALYLANIASEVHLVHRRDSFRSEKILIDRLMKKVEEGKIILHTNRTLDEVLGDNMGVTGVRLKDTQSEATEELSLDGVF
IAIGHAPNTDIFAEQLELNNGYIVVKSGLEGNATATSVDGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDAQK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=78.4126984126984, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI87081763, Length=322, Percent_Identity=35.4037267080745, Blast_Score=148, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6321898, Length=329, Percent_Identity=48.6322188449848, Blast_Score=293, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6320560, Length=322, Percent_Identity=49.3788819875776, Blast_Score=288, Evalue=8e-79,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34247; Mature: 34247

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAMKHSQLLILGSGPAGYTAAIYAARANLKPVLVTGLQQGGQLTTTTEIENWPGDFGET
CCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCC
TGPELMQRMLQHAEKFDTEIIFDHINKVDLSSRPFKLYGDVHTFSCDALIIATGASARYL
CCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEECEEEEECCEEEEEECCCEEEE
GLPSEEAYKGRGVSACATCDGFFYRNKPVAVIGGGNTAVEEALYLANIASEVHLVHRRDS
CCCCHHHHCCCCCEEEEECCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHEEHHCCC
FRSEKILIDRLMKKVEEGKIILHTNRTLDEVLGDNMGVTGVRLKDTQSEATEELSLDGVF
CCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCCCCCEEEEECCHHHHHHHCCCCEEE
IAIGHAPNTDIFAEQLELNNGYIVVKSGLEGNATATSVDGVFAAGDVMDHNYRQAITSAG
EEECCCCCCCHHHHHEECCCCEEEEECCCCCCCCEEECCCEEEECCHHCCHHHHHHHHCC
TGCMAALDAERYLDAQK
CCCEEECCHHHHCCCCC
>Mature Secondary Structure
MNAMKHSQLLILGSGPAGYTAAIYAARANLKPVLVTGLQQGGQLTTTTEIENWPGDFGET
CCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCC
TGPELMQRMLQHAEKFDTEIIFDHINKVDLSSRPFKLYGDVHTFSCDALIIATGASARYL
CCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEECEEEEECCEEEEEECCCEEEE
GLPSEEAYKGRGVSACATCDGFFYRNKPVAVIGGGNTAVEEALYLANIASEVHLVHRRDS
CCCCHHHHCCCCCEEEEECCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHEEHHCCC
FRSEKILIDRLMKKVEEGKIILHTNRTLDEVLGDNMGVTGVRLKDTQSEATEELSLDGVF
CCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCCCCCEEEEECCHHHHHHHCCCCEEE
IAIGHAPNTDIFAEQLELNNGYIVVKSGLEGNATATSVDGVFAAGDVMDHNYRQAITSAG
EEECCCCCCCHHHHHEECCCCEEEEECCCCCCCCEEECCCEEEECCHHCCHHHHHHHHCC
TGCMAALDAERYLDAQK
CCCEEECCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]