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The map label for this gene is fabA [H]

Identifier: 15602349

GI number: 15602349

Start: 566863

End: 567396

Strand: Direct

Name: fabA [H]

Synonym: PM0484

Alternate gene names: 15602349

Gene position: 566863-567396 (Clockwise)

Preceding gene: 15602348

Following gene: 15602351

Centisome position: 25.11

GC content: 46.07

Gene sequence:

>534_bases
ATAATGAACAGTTGTACACCAAATAAAAAGAGTAGCTACAGCTACGAAGATTTACTCGCATCGGGTCGTGGCGAATTATT
TGGCGAAGACGGGCCGCAACTGCCAGCACCAACCATGCTGATGATGGATCGCATTGTCGAAATGAACGAAACTGGTGGGC
AATTTAATAAAGGTTATATCGAAGCAGAACTCGATATTAAGCCGGATTTACCGTTTTTTGGCTGTCACTTTATAGGCGAT
CCTGTGATGCCGGGGTGCTTAGGTTTGGATGCTATGTGGCAACTGGTTGGCTTTTATCTCGGTTGGATTGGCGGCAAAGG
CAAAGGTCGAGCGCTAGGGGTAGGCGAAGTGAAGTTCACAGGACAAATTTTGCCAAGCGCGAAAAAAGTGGTATATCGTA
TTCACATGAAACGTGTTATTAATCGTAAACTTGTGATGGGCATGGCGGATGGTGAAGTGGAAGTAGATGGTCGCGTGATT
TATACCGCAACAGACCTCAAAGTCGGGCTATTTCAAGATACGAGCGCGTTCTAG

Upstream 100 bases:

>100_bases
TAAGCTTACAAGTGTTAGCTATTTTTATTTTTACTCGACTCTGTTAGAATGCCGACAAGCAGAATTTGCTTGTATATCCT
AAAACTGAGGAGAGTTTAAA

Downstream 100 bases:

>100_bases
TGATTTTATCGACTTAAATAGAAATAACAAGATTACCAGCTTATTAGGCTGGTAATCTTTTTTCAGGCTTATTCGTCCAC
AATATCCGCAAATTCAGCAT

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MMNSCTPNKKSSYSYEDLLASGRGELFGEDGPQLPAPTMLMMDRIVEMNETGGQFNKGYIEAELDIKPDLPFFGCHFIGD
PVMPGCLGLDAMWQLVGFYLGWIGGKGKGRALGVGEVKFTGQILPSAKKVVYRIHMKRVINRKLVMGMADGEVEVDGRVI
YTATDLKVGLFQDTSAF

Sequences:

>Translated_177_residues
MMNSCTPNKKSSYSYEDLLASGRGELFGEDGPQLPAPTMLMMDRIVEMNETGGQFNKGYIEAELDIKPDLPFFGCHFIGD
PVMPGCLGLDAMWQLVGFYLGWIGGKGKGRALGVGEVKFTGQILPSAKKVVYRIHMKRVINRKLVMGMADGEVEVDGRVI
YTATDLKVGLFQDTSAF
>Mature_177_residues
MMNSCTPNKKSSYSYEDLLASGRGELFGEDGPQLPAPTMLMMDRIVEMNETGGQFNKGYIEAELDIKPDLPFFGCHFIGD
PVMPGCLGLDAMWQLVGFYLGWIGGKGKGRALGVGEVKFTGQILPSAKKVVYRIHMKRVINRKLVMGMADGEVEVDGRVI
YTATDLKVGLFQDTSAF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=170, Percent_Identity=82.3529411764706, Blast_Score=302, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 19439; Mature: 19439

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNSCTPNKKSSYSYEDLLASGRGELFGEDGPQLPAPTMLMMDRIVEMNETGGQFNKGYI
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEE
EAELDIKPDLPFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWIGGKGKGRALGVGEVKFT
EEEEECCCCCCEEEHEECCCCCCCCHHCHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEE
GQILPSAKKVVYRIHMKRVINRKLVMGMADGEVEVDGRVIYTATDLKVGLFQDTSAF
CCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCEEECCEEEEEECCEEEEEECCCCCC
>Mature Secondary Structure
MMNSCTPNKKSSYSYEDLLASGRGELFGEDGPQLPAPTMLMMDRIVEMNETGGQFNKGYI
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEE
EAELDIKPDLPFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWIGGKGKGRALGVGEVKFT
EEEEECCCCCCEEEHEECCCCCCCCHHCHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEE
GQILPSAKKVVYRIHMKRVINRKLVMGMADGEVEVDGRVIYTATDLKVGLFQDTSAF
CCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCEEECCEEEEEECCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA