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The map label for this gene is argD

Identifier: 15602209

GI number: 15602209

Start: 406387

End: 407583

Strand: Direct

Name: argD

Synonym: PM0344

Alternate gene names: 15602209

Gene position: 406387-407583 (Clockwise)

Preceding gene: 15602208

Following gene: 15602212

Centisome position: 18.0

GC content: 43.02

Gene sequence:

>1197_bases
ATGACACAATATAACAGAGAAATTTTTGACCAAGTCATGATCCAAAACTATGTTCCCGCACAATTTATTCCTGTGCGAGG
CAAGGGGAGTCATGTCTGGGATCAACAAGGCAAAGACTATATCGATTTTACCAGTGGCATTGCTGTTAACAGTTTGGGGC
ATTGCGCCGATGAAATCGTTGACGTATTAAAACAACAAAGTGAAAAGTTATGGCATTCGAGTAACTGGTTTACGAGTGAA
CCTACTTTGGCATTAGCCACAAAATTAGTCGAAAAAACGTTTGCCGAACGGGTGATGTTTGTTAACTCTGGCGCAGAAGC
AAATGAAGCTGCTCTCAAATTGGCGCGTCGTTATGCGGTAGATCATTTTGGTTATCAAAAAAGTAAAATCATTGCCTTTA
AACAAAGTTTTCATGGACGTACGCTGTTTACCGTGAGCGTGGGGGGACAAGCCAAGTATTCTGACGGCTTTGGTCCAAAG
CCTGCGGATATTGTGCATGTGCCGTTTAATGATTTAGCAGCGGTGCAAGCGGTGATGGATGAAAATACTTGTGCGGTGAT
TGTTGAGCCAATTCAGGGCGAAAGTGGGATTCTGCCGGCGAGTCAAGATTTTCTGCAAGGTTTGCGTGAATTGTGTGACC
AACATAATGCGTTGCTGATTTTCGATGAAGTCCAAACTGGCGTGGGACGAACTGGCTATTTATATGCTTATATGAAATAT
GAAGTGGTGCCCGATATTTTGACTTCTGCCAAAGCACTGGGTAATGGGTTTCCAATTGGTGCCATGTTGACAACGCATGA
GATCGCCAAAAGTTTTGCACCTGGCGTGCATGGCACCACCTTTGGTGGCAATCCTCTCGCTTGTGCCGTGGCAGAAAAAG
TGATTGATATCATTTCAGCACCACCATTCTTGCAAAAAATTCAGCGCACTTCTGAAAAATTTATGCAAAAGCTGCAAGAA
ATTAATCAGCAATGTGGCTTATTTAAAGAAATCCGTGGCGAAGGTTTGTTAATTGGTGCAGAGCTTATCGAGCAATATCA
CGGAAGAGCGAGCGAATTTGTCAAAAAAGCAGCAGATAATGGCTTAATGATTTTAGTGGCGGGTCCTAATGTGTTGCGTT
TTGCCCCAGCATTAAATATTAGTGAAGAGGCGTTAGCATTGGGTTTCGAAAGATTGGCGAAAACGTTGCATATATAA

Upstream 100 bases:

>100_bases
ATTTTTTAGGTGCATAGATGAATATTTATTCATTTATATTGACTAAATATTTTTATCTAATTATGCTGATGACGATAATA
ATGCAAAAAAGGATAAGGCA

Downstream 100 bases:

>100_bases
AGCCTAAAAAAGTGCCGTCATGTTATATGACGGCACGATGGTTTACTTGGTTGTTTTAATCGGCGGAATAATACAATTTG
CCAATTTCAATTTTTTGGCG

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTQYNREIFDQVMIQNYVPAQFIPVRGKGSHVWDQQGKDYIDFTSGIAVNSLGHCADEIVDVLKQQSEKLWHSSNWFTSE
PTLALATKLVEKTFAERVMFVNSGAEANEAALKLARRYAVDHFGYQKSKIIAFKQSFHGRTLFTVSVGGQAKYSDGFGPK
PADIVHVPFNDLAAVQAVMDENTCAVIVEPIQGESGILPASQDFLQGLRELCDQHNALLIFDEVQTGVGRTGYLYAYMKY
EVVPDILTSAKALGNGFPIGAMLTTHEIAKSFAPGVHGTTFGGNPLACAVAEKVIDIISAPPFLQKIQRTSEKFMQKLQE
INQQCGLFKEIRGEGLLIGAELIEQYHGRASEFVKKAADNGLMILVAGPNVLRFAPALNISEEALALGFERLAKTLHI

Sequences:

>Translated_398_residues
MTQYNREIFDQVMIQNYVPAQFIPVRGKGSHVWDQQGKDYIDFTSGIAVNSLGHCADEIVDVLKQQSEKLWHSSNWFTSE
PTLALATKLVEKTFAERVMFVNSGAEANEAALKLARRYAVDHFGYQKSKIIAFKQSFHGRTLFTVSVGGQAKYSDGFGPK
PADIVHVPFNDLAAVQAVMDENTCAVIVEPIQGESGILPASQDFLQGLRELCDQHNALLIFDEVQTGVGRTGYLYAYMKY
EVVPDILTSAKALGNGFPIGAMLTTHEIAKSFAPGVHGTTFGGNPLACAVAEKVIDIISAPPFLQKIQRTSEKFMQKLQE
INQQCGLFKEIRGEGLLIGAELIEQYHGRASEFVKKAADNGLMILVAGPNVLRFAPALNISEEALALGFERLAKTLHI
>Mature_397_residues
TQYNREIFDQVMIQNYVPAQFIPVRGKGSHVWDQQGKDYIDFTSGIAVNSLGHCADEIVDVLKQQSEKLWHSSNWFTSEP
TLALATKLVEKTFAERVMFVNSGAEANEAALKLARRYAVDHFGYQKSKIIAFKQSFHGRTLFTVSVGGQAKYSDGFGPKP
ADIVHVPFNDLAAVQAVMDENTCAVIVEPIQGESGILPASQDFLQGLRELCDQHNALLIFDEVQTGVGRTGYLYAYMKYE
VVPDILTSAKALGNGFPIGAMLTTHEIAKSFAPGVHGTTFGGNPLACAVAEKVIDIISAPPFLQKIQRTSEKFMQKLQEI
NQQCGLFKEIRGEGLLIGAELIEQYHGRASEFVKKAADNGLMILVAGPNVLRFAPALNISEEALALGFERLAKTLHI

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily

Homologues:

Organism=Homo sapiens, GI4557809, Length=387, Percent_Identity=35.9173126614987, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=36.3333333333333, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI13994255, Length=427, Percent_Identity=29.9765807962529, Blast_Score=174, Evalue=9e-44,
Organism=Homo sapiens, GI37574042, Length=414, Percent_Identity=28.0193236714976, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI24119277, Length=398, Percent_Identity=28.1407035175879, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI226442705, Length=414, Percent_Identity=27.536231884058, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI226442709, Length=387, Percent_Identity=28.1653746770026, Blast_Score=129, Evalue=4e-30,
Organism=Escherichia coli, GI1789759, Length=395, Percent_Identity=62.5316455696203, Blast_Score=521, Evalue=1e-149,
Organism=Escherichia coli, GI1788044, Length=388, Percent_Identity=60.3092783505155, Blast_Score=499, Evalue=1e-142,
Organism=Escherichia coli, GI1789016, Length=399, Percent_Identity=33.8345864661654, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI145693181, Length=390, Percent_Identity=32.8205128205128, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1787560, Length=392, Percent_Identity=32.1428571428571, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1786349, Length=316, Percent_Identity=30.0632911392405, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786991, Length=319, Percent_Identity=29.7805642633229, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI25144271, Length=400, Percent_Identity=33.75, Blast_Score=225, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=30.3240740740741, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI25144274, Length=269, Percent_Identity=33.8289962825279, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=415, Percent_Identity=25.5421686746988, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17541228, Length=430, Percent_Identity=26.9767441860465, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71981843, Length=180, Percent_Identity=30.5555555555556, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=397, Percent_Identity=41.0579345088161, Blast_Score=296, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6323470, Length=405, Percent_Identity=35.8024691358025, Blast_Score=228, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6324386, Length=404, Percent_Identity=28.2178217821782, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=455, Percent_Identity=24.6153846153846, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357415, Length=398, Percent_Identity=33.9195979899498, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI161085790, Length=416, Percent_Identity=29.0865384615385, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28574759, Length=405, Percent_Identity=29.3827160493827, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21356575, Length=413, Percent_Identity=30.2663438256659, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI281366494, Length=301, Percent_Identity=24.5847176079734, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24667139, Length=301, Percent_Identity=24.5847176079734, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24667143, Length=301, Percent_Identity=24.5847176079734, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): ARGD_PASMU (Q9CNT1)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245281.1
- ProteinModelPortal:   Q9CNT1
- SMR:   Q9CNT1
- GeneID:   1243691
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0344
- NMPDR:   fig|272843.1.peg.344
- HOGENOM:   HBG725944
- OMA:   NATFADR
- ProtClustDB:   PRK05093
- BioCyc:   PMUL272843:PM0344-MONOMER
- BRENDA:   2.6.1.11
- GO:   GO:0005737
- HAMAP:   MF_01107
- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PANTHER:   PTHR11986
- PANTHER:   PTHR11986:SF19
- TIGRFAMs:   TIGR03246
- TIGRFAMs:   TIGR00707

Pfam domain/function: PF00202 Aminotran_3; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.11

Molecular weight: Translated: 43713; Mature: 43581

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: BINDING 137-137 BINDING 140-140 BINDING 279-279 BINDING 280-280

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQYNREIFDQVMIQNYVPAQFIPVRGKGSHVWDQQGKDYIDFTSGIAVNSLGHCADEIV
CCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHCCCCCCHHCCCCHHHHHHHHHHHHH
DVLKQQSEKLWHSSNWFTSEPTLALATKLVEKTFAERVMFVNSGAEANEAALKLARRYAV
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHH
DHFGYQKSKIIAFKQSFHGRTLFTVSVGGQAKYSDGFGPKPADIVHVPFNDLAAVQAVMD
HHCCCCCHHEEEEECCCCCCEEEEEEECCCEECCCCCCCCCCCEEECCCHHHHHHHHHHC
ENTCAVIVEPIQGESGILPASQDFLQGLRELCDQHNALLIFDEVQTGVGRTGYLYAYMKY
CCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCEEEEEEEH
EVVPDILTSAKALGNGFPIGAMLTTHEIAKSFAPGVHGTTFGGNPLACAVAEKVIDIISA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
PPFLQKIQRTSEKFMQKLQEINQQCGLFKEIRGEGLLIGAELIEQYHGRASEFVKKAADN
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEHHHHHHHHCCHHHHHHHHHCCC
GLMILVAGPNVLRFAPALNISEEALALGFERLAKTLHI
CEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQYNREIFDQVMIQNYVPAQFIPVRGKGSHVWDQQGKDYIDFTSGIAVNSLGHCADEIV
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHCCCCCCHHCCCCHHHHHHHHHHHHH
DVLKQQSEKLWHSSNWFTSEPTLALATKLVEKTFAERVMFVNSGAEANEAALKLARRYAV
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHH
DHFGYQKSKIIAFKQSFHGRTLFTVSVGGQAKYSDGFGPKPADIVHVPFNDLAAVQAVMD
HHCCCCCHHEEEEECCCCCCEEEEEEECCCEECCCCCCCCCCCEEECCCHHHHHHHHHHC
ENTCAVIVEPIQGESGILPASQDFLQGLRELCDQHNALLIFDEVQTGVGRTGYLYAYMKY
CCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCEEEEEEEH
EVVPDILTSAKALGNGFPIGAMLTTHEIAKSFAPGVHGTTFGGNPLACAVAEKVIDIISA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
PPFLQKIQRTSEKFMQKLQEINQQCGLFKEIRGEGLLIGAELIEQYHGRASEFVKKAADN
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEHHHHHHHHCCHHHHHHHHHCCC
GLMILVAGPNVLRFAPALNISEEALALGFERLAKTLHI
CEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100