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The map label for this gene is hscB

Identifier: 15602186

GI number: 15602186

Start: 376334

End: 376852

Strand: Direct

Name: hscB

Synonym: PM0321

Alternate gene names: 15602186

Gene position: 376334-376852 (Clockwise)

Preceding gene: 15602185

Following gene: 15602187

Centisome position: 16.67

GC content: 38.34

Gene sequence:

>519_bases
ATGAACCCATTTAATATTTTTGATTTACCAGTTGATTTTCATGTTGATCAAGCGACATTATCGGCACGTTATCTTGCCTT
ACAGAAATCCTTGCATCCTGACAATTTCACTACGCATTCTGCACAAGAGCAGCGTTTAGCGATGCAACGGTCAGCAGAAG
TCAATGATGCGTTACAAATTTTAAAAGATCCGATTTTGCGTGCGGAGACTATCATTGCGATTTATACCGGTGAACAACAA
AATATTGAAGAAAATAGCACCCGTGATATGGCATTTTTGATGCAACAAATGCAATGGCGGGAACAGCTAGAAAATATTGA
AGCGCAGCAAGACAGTGATCAACTCGTGGCGTTCAGTGCAGATATTGAACAAACGCAACAGGCTTTGTTAAGTGAATTAG
CCGATGCATTGTCAAGCCAACAGTGGCAACAAGCAAAAGTCATTAACGACAAATTACGTTTTATTAAAAAATTATTGCTT
GAAGTAGAACGTGTTGAAGAAAAGCTATTAGACTTTTAA

Upstream 100 bases:

>100_bases
TGAAGGCTTTAAGTTCAATAATCCGAATGTGAAAGATCAATGTGGTTGCGGAGAAAGTTTCCACGTTTAGCTGTTTTTTT
ATCTGATATTTGAGTGAAAG

Downstream 100 bases:

>100_bases
GTAGATTAAAACAACGACAAAATAAAACTGCTATAATATAAAGTCAATAGGAAATAATAAGAGAATAGAGATAAACAATG
GCATTACTTCAAATTGCAGA

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MNPFNIFDLPVDFHVDQATLSARYLALQKSLHPDNFTTHSAQEQRLAMQRSAEVNDALQILKDPILRAETIIAIYTGEQQ
NIEENSTRDMAFLMQQMQWREQLENIEAQQDSDQLVAFSADIEQTQQALLSELADALSSQQWQQAKVINDKLRFIKKLLL
EVERVEEKLLDF

Sequences:

>Translated_172_residues
MNPFNIFDLPVDFHVDQATLSARYLALQKSLHPDNFTTHSAQEQRLAMQRSAEVNDALQILKDPILRAETIIAIYTGEQQ
NIEENSTRDMAFLMQQMQWREQLENIEAQQDSDQLVAFSADIEQTQQALLSELADALSSQQWQQAKVINDKLRFIKKLLL
EVERVEEKLLDF
>Mature_172_residues
MNPFNIFDLPVDFHVDQATLSARYLALQKSLHPDNFTTHSAQEQRLAMQRSAEVNDALQILKDPILRAETIIAIYTGEQQ
NIEENSTRDMAFLMQQMQWREQLENIEAQQDSDQLVAFSADIEQTQQALLSELADALSSQQWQQAKVINDKLRFIKKLLL
EVERVEEKLLDF

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Escherichia coli, GI1788876, Length=172, Percent_Identity=37.2093023255814, Blast_Score=113, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSCB_PASMU (Q9CNV3)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245258.1
- ProteinModelPortal:   Q9CNV3
- SMR:   Q9CNV3
- GeneID:   1243668
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0321
- NMPDR:   fig|272843.1.peg.321
- HOGENOM:   HBG751004
- OMA:   LNDAYQT
- ProtClustDB:   PRK01773
- BioCyc:   PMUL272843:PM0321-MONOMER
- HAMAP:   MF_00682
- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:1.20.1280.20
- SMART:   SM00271
- TIGRFAMs:   TIGR00714

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C; SSF46565 DnaJ_N; SSF47144 HSC20_C

EC number: NA

Molecular weight: Translated: 19934; Mature: 19934

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPFNIFDLPVDFHVDQATLSARYLALQKSLHPDNFTTHSAQEQRLAMQRSAEVNDALQI
CCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHH
LKDPILRAETIIAIYTGEQQNIEENSTRDMAFLMQQMQWREQLENIEAQQDSDQLVAFSA
HHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHH
DIEQTQQALLSELADALSSQQWQQAKVINDKLRFIKKLLLEVERVEEKLLDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPFNIFDLPVDFHVDQATLSARYLALQKSLHPDNFTTHSAQEQRLAMQRSAEVNDALQI
CCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHH
LKDPILRAETIIAIYTGEQQNIEENSTRDMAFLMQQMQWREQLENIEAQQDSDQLVAFSA
HHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHH
DIEQTQQALLSELADALSSQQWQQAKVINDKLRFIKKLLLEVERVEEKLLDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100