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The map label for this gene is pheA [H]

Identifier: 15602015

GI number: 15602015

Start: 177405

End: 178568

Strand: Direct

Name: pheA [H]

Synonym: PM0150

Alternate gene names: 15602015

Gene position: 177405-178568 (Clockwise)

Preceding gene: 15602014

Following gene: 15602022

Centisome position: 7.86

GC content: 39.09

Gene sequence:

>1164_bases
ATGTCTTTGGATTTAAGTGAGATTCGTCAACAGATCACACAACTTGATCGAAATTTATTGAAATTATTGTCAGAGCGTCA
TCGCTTAGCCTTTGATGTGGCGCGCAGTAAAGAAATCACGCAGAAACCCCTTCGTGATCTTGAGCGTGAACAACAATTGT
TGCAAGAACTCATTCAATTTGCTGAAAATCAAAACTACCAATTAGAAGCACAATATATTACCGATATTTTTCAGCGTATT
ATTGAAGATTCCGTTGCCACACAACAAGTTTATTTGCAAAAAAAACTGAATGCGCAACGTGAACAGAATATCCATATTGC
GTTTTTAGGCAAACGTGGCTCTTATTCACATTTGGCGGCGAGAAGTTATGCAACGCGTTATCAAGAAACCTTTGTGGAAC
TGAGCTGTCGCTCATTTGATGAGATTTTTGAGAAAGTCAGCGCAGGCGAGGCAGATTATGGTGTGTTACCTCTGGAAAAT
ACCACGTCGGGTGCTATTAATGAAGTGTATGATTTATTGCAACATACCGATCTTTCTTTAGTAGGTGAGCTGGCGTATCC
GATTCGGCATTGTGTCTTAGTGAATGGACAGGATGATTTGAATCAAATTGAAACATTATATAGTCATCCGCAAGTTATCC
AACAATGTAGCCAATTTATTAAAGGCTTAGAACGTGTTCACATTGAATATTGTGAAAGCAGCTCTCATGCGATGCAATTA
GTGGCAAGCTTAAATAAGCCGAATATTGCAGCGTTAGGAAATGCGGATGGCGGGGCGTTATACGGTTTAACGGTATTGAA
ATCAGATATAGCCAACCAACCCAACAATATTACTCGTTTCATTGTGGTAGCGAAGAAACCATTGCAAGTGTCACCACAGA
TTCACACGAAAACGCTATTGTTGATGACCACATCGCAACAAGCGGGGGCATTAGTTGATGCTTTATTCGTGTTTAAAAAG
CATCAAATTAATATGACCAAACTGGAATCACGTCCAATCTATGGTAAGCCATGGGAAGAAATGTTTTATCTTGAAATTGA
GGCGAATATTCATAATCCGGAGACACAGCAAGCTTTAGACGAGCTAAAACAATATAGTCATTATTTAAAAGTATTGGGCT
GTTATCCAAGTGAAATTATTAAGCCTGTTGAGCTCACACCTTAA

Upstream 100 bases:

>100_bases
TTTAGATCGCCAAGCCGTTAACGAAATTCTATATGCCGCACTTTAAGAGGCAGTAAAGTGCGGTCCGTTTTTGCTAAATT
TTCAGCCTACAGGAAAGGAT

Downstream 100 bases:

>100_bases
ATAAAACGTGGGATTTACCCACGTTTTTCTTGATACAGCTGTCTAACAGATTCTCGCCAAACTAATTGAGGTTCAAGTAA
TAATGTACGGTGTTTTGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSLDLSEIRQQITQLDRNLLKLLSERHRLAFDVARSKEITQKPLRDLEREQQLLQELIQFAENQNYQLEAQYITDIFQRI
IEDSVATQQVYLQKKLNAQREQNIHIAFLGKRGSYSHLAARSYATRYQETFVELSCRSFDEIFEKVSAGEADYGVLPLEN
TTSGAINEVYDLLQHTDLSLVGELAYPIRHCVLVNGQDDLNQIETLYSHPQVIQQCSQFIKGLERVHIEYCESSSHAMQL
VASLNKPNIAALGNADGGALYGLTVLKSDIANQPNNITRFIVVAKKPLQVSPQIHTKTLLLMTTSQQAGALVDALFVFKK
HQINMTKLESRPIYGKPWEEMFYLEIEANIHNPETQQALDELKQYSHYLKVLGCYPSEIIKPVELTP

Sequences:

>Translated_387_residues
MSLDLSEIRQQITQLDRNLLKLLSERHRLAFDVARSKEITQKPLRDLEREQQLLQELIQFAENQNYQLEAQYITDIFQRI
IEDSVATQQVYLQKKLNAQREQNIHIAFLGKRGSYSHLAARSYATRYQETFVELSCRSFDEIFEKVSAGEADYGVLPLEN
TTSGAINEVYDLLQHTDLSLVGELAYPIRHCVLVNGQDDLNQIETLYSHPQVIQQCSQFIKGLERVHIEYCESSSHAMQL
VASLNKPNIAALGNADGGALYGLTVLKSDIANQPNNITRFIVVAKKPLQVSPQIHTKTLLLMTTSQQAGALVDALFVFKK
HQINMTKLESRPIYGKPWEEMFYLEIEANIHNPETQQALDELKQYSHYLKVLGCYPSEIIKPVELTP
>Mature_386_residues
SLDLSEIRQQITQLDRNLLKLLSERHRLAFDVARSKEITQKPLRDLEREQQLLQELIQFAENQNYQLEAQYITDIFQRII
EDSVATQQVYLQKKLNAQREQNIHIAFLGKRGSYSHLAARSYATRYQETFVELSCRSFDEIFEKVSAGEADYGVLPLENT
TSGAINEVYDLLQHTDLSLVGELAYPIRHCVLVNGQDDLNQIETLYSHPQVIQQCSQFIKGLERVHIEYCESSSHAMQLV
ASLNKPNIAALGNADGGALYGLTVLKSDIANQPNNITRFIVVAKKPLQVSPQIHTKTLLLMTTSQQAGALVDALFVFKKH
QINMTKLESRPIYGKPWEEMFYLEIEANIHNPETQQALDELKQYSHYLKVLGCYPSEIIKPVELTP

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=382, Percent_Identity=54.1884816753927, Blast_Score=424, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6324013, Length=326, Percent_Identity=25.4601226993865, Blast_Score=93, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 44191; Mature: 44060

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDLSEIRQQITQLDRNLLKLLSERHRLAFDVARSKEITQKPLRDLEREQQLLQELIQF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AENQNYQLEAQYITDIFQRIIEDSVATQQVYLQKKLNAQREQNIHIAFLGKRGSYSHLAA
HCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEEEECCCCCHHHHH
RSYATRYQETFVELSCRSFDEIFEKVSAGEADYGVLPLENTTSGAINEVYDLLQHTDLSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHCCHHH
VGELAYPIRHCVLVNGQDDLNQIETLYSHPQVIQQCSQFIKGLERVHIEYCESSSHAMQL
HHHHHHHHHHEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VASLNKPNIAALGNADGGALYGLTVLKSDIANQPNNITRFIVVAKKPLQVSPQIHTKTLL
HHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCEEEE
LMTTSQQAGALVDALFVFKKHQINMTKLESRPIYGKPWEEMFYLEIEANIHNPETQQALD
EEECCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHEEEEEEEECCCCCHHHHHHH
ELKQYSHYLKVLGCYPSEIIKPVELTP
HHHHHHHHHHHHCCCHHHHCCCCCCCC
>Mature Secondary Structure 
SLDLSEIRQQITQLDRNLLKLLSERHRLAFDVARSKEITQKPLRDLEREQQLLQELIQF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AENQNYQLEAQYITDIFQRIIEDSVATQQVYLQKKLNAQREQNIHIAFLGKRGSYSHLAA
HCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEEEECCCCCHHHHH
RSYATRYQETFVELSCRSFDEIFEKVSAGEADYGVLPLENTTSGAINEVYDLLQHTDLSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHCCHHH
VGELAYPIRHCVLVNGQDDLNQIETLYSHPQVIQQCSQFIKGLERVHIEYCESSSHAMQL
HHHHHHHHHHEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VASLNKPNIAALGNADGGALYGLTVLKSDIANQPNNITRFIVVAKKPLQVSPQIHTKTLL
HHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCEEEE
LMTTSQQAGALVDALFVFKKHQINMTKLESRPIYGKPWEEMFYLEIEANIHNPETQQALD
EEECCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHEEEEEEEECCCCCHHHHHHH
ELKQYSHYLKVLGCYPSEIIKPVELTP
HHHHHHHHHHHHCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]