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The map label for this gene is rnz [H]

Identifier: 15595100

GI number: 15595100

Start: 798057

End: 799016

Strand: Reverse

Name: rnz [H]

Synonym: BB0755

Alternate gene names: 15595100

Gene position: 799016-798057 (Counterclockwise)

Preceding gene: 15595101

Following gene: 15595099

Centisome position: 87.73

GC content: 29.9

Gene sequence:

>960_bases
TTGGGATTTAATATTAATATCATAGGAACTGGAGGAACAAGGCCACTCCACAATAGATATTTGTCATCCGTACTAATCGA
ATACGATGGAGATAACTTTTTGTTCGATTGTGGTGAAGGAACCCAAATGTCTTTAAGGAAACAAAAAATATCCTGGCAAA
AAATAAAAATGATTTGCATTACACACTTACATGCTGACCACATCACGGGACTACTTGGAATAGTAATGCTAATGTCACAA
AGTGGAGAAACAAGAAAAGAACCATTAATAATCGCTGGACCTGTTGGAATAAAAAACTATACACAAGCTAATATAAATAT
GCTTAAAATATATAAAAACTATGAAATAATTTATAAAGAAATAATCATAGATAAAACCGAAAAAATAATATATGAAGATA
AAACAAAAAAAATTGAATACACTAAACTAAAACATTCAATAGAATGTGTTGGATATTTATTTATAGAAAAAGATAAACCC
GGCAAATTCAACACAGAAAAAGCAGAAGAGCTAAATATTCCTAAAGGGCCTATTAGAAAAGCCCTACAAGATGGAAAAGA
AATATTGGTAAACGGAAAAATTATAAAGCCATCAGAAATACTTGGAAAATCTAAAAAAGGACTAAAAGTTGCATACATTA
CAGATACTGGTTATTTTAAAGAACTCATACAGCAAATCAAAAATTTTAACCTTGTAATAATTGAGAGCACATTTAAAAAT
GAGCTAAAAAAAGAAGCCGATAAAAAACTTCACTTAACAGCTGGCGGGGCTGCAAATATTGTCAAGCAAGCAAAAGTTTT
ACAAACAGGACTTATCCATTTTAGTGAAAGATATACATTAAGAAAAGATCTTGAAAACTTACTAAAGGAGGCAAAATTGG
AACATCCAGACGGAGAAATTTTTTTAACAAGAGATGGAATGAGGCTTGAAGCAAACAAAAATAACTTTATTATTAAATAG

Upstream 100 bases:

>100_bases
TAAAATAATTCTTATCCAAAGAGAAACTAAGAGTGAAACAAGATTTAACAAAGCAAATAAAATTAATTGACACTTACAAA
ACAAACCAGGAGAATAATCT

Downstream 100 bases:

>100_bases
GAGGGTATATGATAAATGTAGAAAAAGTTACTAAAATGTATGGGCCATTTACAGCACTATTTAATGTTAGCTTTAAGGTT
GAAGAAGGCGAAGTACTTGG

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MGFNINIIGTGGTRPLHNRYLSSVLIEYDGDNFLFDCGEGTQMSLRKQKISWQKIKMICITHLHADHITGLLGIVMLMSQ
SGETRKEPLIIAGPVGIKNYTQANINMLKIYKNYEIIYKEIIIDKTEKIIYEDKTKKIEYTKLKHSIECVGYLFIEKDKP
GKFNTEKAEELNIPKGPIRKALQDGKEILVNGKIIKPSEILGKSKKGLKVAYITDTGYFKELIQQIKNFNLVIIESTFKN
ELKKEADKKLHLTAGGAANIVKQAKVLQTGLIHFSERYTLRKDLENLLKEAKLEHPDGEIFLTRDGMRLEANKNNFIIK

Sequences:

>Translated_319_residues
MGFNINIIGTGGTRPLHNRYLSSVLIEYDGDNFLFDCGEGTQMSLRKQKISWQKIKMICITHLHADHITGLLGIVMLMSQ
SGETRKEPLIIAGPVGIKNYTQANINMLKIYKNYEIIYKEIIIDKTEKIIYEDKTKKIEYTKLKHSIECVGYLFIEKDKP
GKFNTEKAEELNIPKGPIRKALQDGKEILVNGKIIKPSEILGKSKKGLKVAYITDTGYFKELIQQIKNFNLVIIESTFKN
ELKKEADKKLHLTAGGAANIVKQAKVLQTGLIHFSERYTLRKDLENLLKEAKLEHPDGEIFLTRDGMRLEANKNNFIIK
>Mature_318_residues
GFNINIIGTGGTRPLHNRYLSSVLIEYDGDNFLFDCGEGTQMSLRKQKISWQKIKMICITHLHADHITGLLGIVMLMSQS
GETRKEPLIIAGPVGIKNYTQANINMLKIYKNYEIIYKEIIIDKTEKIIYEDKTKKIEYTKLKHSIECVGYLFIEKDKPG
KFNTEKAEELNIPKGPIRKALQDGKEILVNGKIIKPSEILGKSKKGLKVAYITDTGYFKELIQQIKNFNLVIIESTFKNE
LKKEADKKLHLTAGGAANIVKQAKVLQTGLIHFSERYTLRKDLENLLKEAKLEHPDGEIFLTRDGMRLEANKNNFIIK

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

Organism=Homo sapiens, GI8922122, Length=318, Percent_Identity=29.2452830188679, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI87082078, Length=299, Percent_Identity=29.7658862876254, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 36384; Mature: 36253

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFNINIIGTGGTRPLHNRYLSSVLIEYDGDNFLFDCGEGTQMSLRKQKISWQKIKMICI
CCEEEEEEECCCCCHHHHHHHHHEEEEECCCEEEEECCCCCCHHHHHHHCCHHHEEEEHH
THLHADHITGLLGIVMLMSQSGETRKEPLIIAGPVGIKNYTQANINMLKIYKNYEIIYKE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCHHHEEHH
IIIDKTEKIIYEDKTKKIEYTKLKHSIECVGYLFIEKDKPGKFNTEKAEELNIPKGPIRK
HHHCCCHHEEECCCCCEEEHHHHHHHEEEEEEEEEECCCCCCCCCCCHHHCCCCHHHHHH
ALQDGKEILVNGKIIKPSEILGKSKKGLKVAYITDTGYFKELIQQIKNFNLVIIESTFKN
HHHCCCEEEEECEEECHHHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEEHHHHH
ELKKEADKKLHLTAGGAANIVKQAKVLQTGLIHFSERYTLRKDLENLLKEAKLEHPDGEI
HHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
FLTRDGMRLEANKNNFIIK
EEEECCEEEEECCCCEEEC
>Mature Secondary Structure 
GFNINIIGTGGTRPLHNRYLSSVLIEYDGDNFLFDCGEGTQMSLRKQKISWQKIKMICI
CEEEEEEECCCCCHHHHHHHHHEEEEECCCEEEEECCCCCCHHHHHHHCCHHHEEEEHH
THLHADHITGLLGIVMLMSQSGETRKEPLIIAGPVGIKNYTQANINMLKIYKNYEIIYKE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCHHHEEHH
IIIDKTEKIIYEDKTKKIEYTKLKHSIECVGYLFIEKDKPGKFNTEKAEELNIPKGPIRK
HHHCCCHHEEECCCCCEEEHHHHHHHEEEEEEEEEECCCCCCCCCCCHHHCCCCHHHHHH
ALQDGKEILVNGKIIKPSEILGKSKKGLKVAYITDTGYFKELIQQIKNFNLVIIESTFKN
HHHCCCEEEEECEEECHHHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEEHHHHH
ELKKEADKKLHLTAGGAANIVKQAKVLQTGLIHFSERYTLRKDLENLLKEAKLEHPDGEI
HHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
FLTRDGMRLEANKNNFIIK
EEEECCEEEEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA