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The map label for this gene is apeB

Identifier: 15594972

GI number: 15594972

Start: 657546

End: 658817

Strand: Reverse

Name: apeB

Synonym: BB0627

Alternate gene names: 15594972

Gene position: 658817-657546 (Counterclockwise)

Preceding gene: 15594974

Following gene: 15594971

Centisome position: 72.34

GC content: 30.31

Gene sequence:

>1272_bases
ATGGTGAMTGMTAAAACACTAGAACCAAAATTTTTTCAAAGTCTGCTAGACAATAGCCCTACCCCTTATCACTTAGTAAA
CTATATTGAAGAGAAATTAATAAATTATTTTAATGCACAACAATTAAAACTTAATGAAAAATGGAAAATTAAAACAGGAT
CATATTACATAAAAAAAGAAGGAACTAGCCTTATTGCCTTTAATATTGATGTCAAAAAAAAATATGAACCGTTTCTAATA
GCAGCAGCACATACAGACAGTCCGGGATTAAAATTAAAAATAGACGCAACAGAAAAAGTAAGTGGTGTGTTTTATAACCA
TATTGAAGTTTATGGTAGTCCAATAATTTCTACTTGGATTGACAGAGACTTAAGCTTAGCAGGAATTGTATATTTCAAAA
AAAATGAGAATATTGAATCAAAATTAATCAACATTGAAAACATAGGAATTATTCCAAACCTTGCAATCCATTTAAACCGA
CAAATTAACGAAGGATTTAAATACAATGCTCATGACAATTTAACAGTAATCAGTAGCACTAAAAAAGCAATAAAAGATAA
TATCTTAGAACAACTTGGAATAGAGTGTGAAAATTTTCTATCTTGTGATTTAATATTCACAGAATCACAACCTTCTAAAA
TAATAGGAACTGAAGGAGAATTTTTGGCTTCTAAAAATCTTGACAACAAATCGGGATGCCATGCAATCATGAATTCTTAT
GTTCATACAAGCAATGATAAAAATAAAATAGCTGTATTTTTTGATAACGAAGAAGTAGGTTCTTTAACATCAAGAGGCGC
TGATTCAAATTTTTTATCAGAAGTTTTAGAAAGAATCGATATTGCTCTTGATTTAACCAGAGAAGAGCATTTAATAAAAA
CAAACAAATCATTTAATATCTCAATTGACAGCGTTCACGGCATTCATCCGGGTTATACATCTAAACATGATCCAAACTAT
CAAGCAAATCTAGGTAAGGGCGTAGTTGTAAAAAATAGTGCTAATTTCAGATATGCAACAACTTCAACAGGATTTGCAAA
ATTAAAAAATTTGGCTATTAAAAACAATATTAAGATTCAAGAAATAATAATGAAAGCAAATGTTCCTTCAGGCACAACAA
TTGGTCCAATCTCAAATGCAAGAACAGGAATAGAAACTATTGACATTGGAACACCAATGTGGGCAATGCATTCCCTGCGC
GAAACAGTATCAATAGCTGACCACATAGAAGCAATTAAATTGCTAAGGGCTTTCTTTGAAAAAGGAATTTAA

Upstream 100 bases:

>100_bases
CTAACAAAACACTTTCTCATAACAAACTCCTAACTAACAGTTAAAAACTATTATAATAGAATATATAGCTATAAAGCAAT
AAAACTAAAGGAGAACACCT

Downstream 100 bases:

>100_bases
AATTGGAAAAAATAAAAGAAATAATTGTAGTTGAGGGAAAAGATGATCTTAAAAGAATCAAAGAATCTTTTGACTGCACA
GTAATAGAAACAAAAGGATT

Product: aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MVXXKTLEPKFFQSLLDNSPTPYHLVNYIEEKLINYFNAQQLKLNEKWKIKTGSYYIKKEGTSLIAFNIDVKKKYEPFLI
AAAHTDSPGLKLKIDATEKVSGVFYNHIEVYGSPIISTWIDRDLSLAGIVYFKKNENIESKLINIENIGIIPNLAIHLNR
QINEGFKYNAHDNLTVISSTKKAIKDNILEQLGIECENFLSCDLIFTESQPSKIIGTEGEFLASKNLDNKSGCHAIMNSY
VHTSNDKNKIAVFFDNEEVGSLTSRGADSNFLSEVLERIDIALDLTREEHLIKTNKSFNISIDSVHGIHPGYTSKHDPNY
QANLGKGVVVKNSANFRYATTSTGFAKLKNLAIKNNIKIQEIIMKANVPSGTTIGPISNARTGIETIDIGTPMWAMHSLR
ETVSIADHIEAIKLLRAFFEKGI

Sequences:

>Translated_423_residues
MVXXKTLEPKFFQSLLDNSPTPYHLVNYIEEKLINYFNAQQLKLNEKWKIKTGSYYIKKEGTSLIAFNIDVKKKYEPFLI
AAAHTDSPGLKLKIDATEKVSGVFYNHIEVYGSPIISTWIDRDLSLAGIVYFKKNENIESKLINIENIGIIPNLAIHLNR
QINEGFKYNAHDNLTVISSTKKAIKDNILEQLGIECENFLSCDLIFTESQPSKIIGTEGEFLASKNLDNKSGCHAIMNSY
VHTSNDKNKIAVFFDNEEVGSLTSRGADSNFLSEVLERIDIALDLTREEHLIKTNKSFNISIDSVHGIHPGYTSKHDPNY
QANLGKGVVVKNSANFRYATTSTGFAKLKNLAIKNNIKIQEIIMKANVPSGTTIGPISNARTGIETIDIGTPMWAMHSLR
ETVSIADHIEAIKLLRAFFEKGI
>Mature_423_residues
MVXXKTLEPKFFQSLLDNSPTPYHLVNYIEEKLINYFNAQQLKLNEKWKIKTGSYYIKKEGTSLIAFNIDVKKKYEPFLI
AAAHTDSPGLKLKIDATEKVSGVFYNHIEVYGSPIISTWIDRDLSLAGIVYFKKNENIESKLINIENIGIIPNLAIHLNR
QINEGFKYNAHDNLTVISSTKKAIKDNILEQLGIECENFLSCDLIFTESQPSKIIGTEGEFLASKNLDNKSGCHAIMNSY
VHTSNDKNKIAVFFDNEEVGSLTSRGADSNFLSEVLERIDIALDLTREEHLIKTNKSFNISIDSVHGIHPGYTSKHDPNY
QANLGKGVVVKNSANFRYATTSTGFAKLKNLAIKNNIKIQEIIMKANVPSGTTIGPISNARTGIETIDIGTPMWAMHSLR
ETVSIADHIEAIKLLRAFFEKGI

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family

Homologues:

Organism=Homo sapiens, GI156416028, Length=447, Percent_Identity=32.662192393736, Blast_Score=232, Evalue=6e-61,
Organism=Caenorhabditis elegans, GI17552916, Length=449, Percent_Identity=32.9621380846325, Blast_Score=221, Evalue=5e-58,
Organism=Saccharomyces cerevisiae, GI6321905, Length=465, Percent_Identity=33.5483870967742, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6322746, Length=450, Percent_Identity=27.3333333333333, Blast_Score=130, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APEB_BORBU (O51572)

Other databases:

- EMBL:   AE000783
- PIR:   B70178
- RefSeq:   NP_212761.1
- ProteinModelPortal:   O51572
- SMR:   O51572
- EnsemblBacteria:   EBBORT00000009007
- GeneID:   1195478
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0627
- NMPDR:   fig|224326.1.peg.1011
- TIGR:   BB_0627
- GeneTree:   EBGT00050000007037
- HOGENOM:   HBG630643
- OMA:   SPSPFHA
- PhylomeDB:   O51572
- ProtClustDB:   PRK02813
- BioCyc:   BBUR224326:BB_0627-MONOMER
- GO:   GO:0005773
- GO:   GO:0006508
- HAMAP:   MF_00467
- InterPro:   IPR022984
- InterPro:   IPR001948
- PRINTS:   PR00932

Pfam domain/function: PF02127 Peptidase_M18

EC number: NA

Molecular weight: Translated: 47273; Mature: 47273

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVXXKTLEPKFFQSLLDNSPTPYHLVNYIEEKLINYFNAQQLKLNEKWKIKTGSYYIKKE
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCEEEEEC
GTSLIAFNIDVKKKYEPFLIAAAHTDSPGLKLKIDATEKVSGVFYNHIEVYGSPIISTWI
CCEEEEEEEEECCCCCCEEEEEEECCCCCEEEEEECCHHHCHHEEEEEEECCCCHHHHHH
DRDLSLAGIVYFKKNENIESKLINIENIGIIPNLAIHLNRQINEGFKYNAHDNLTVISST
CCCCCEEEEEEEECCCCHHHHEEEEECCCCCCCEEEEEECHHCCCCEECCCCCEEEEECH
KKAIKDNILEQLGIECENFLSCDLIFTESQPSKIIGTEGEFLASKNLDNKSGCHAIMNSY
HHHHHHHHHHHHCCCCHHCEEEEEEEECCCCCEEECCCCCEEEECCCCCCCHHHHHHHHH
VHTSNDKNKIAVFFDNEEVGSLTSRGADSNFLSEVLERIDIALDLTREEHLIKTNKSFNI
HCCCCCCCEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHEEEEECCCHHEEECCCCEEE
SIDSVHGIHPGYTSKHDPNYQANLGKGVVVKNSANFRYATTSTGFAKLKNLAIKNNIKIQ
EEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCHHHHHHHHHHCCCCEEE
EIIMKANVPSGTTIGPISNARTGIETIDIGTPMWAMHSLRETVSIADHIEAIKLLRAFFE
HEEEECCCCCCCEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGI
HCC
>Mature Secondary Structure
MVXXKTLEPKFFQSLLDNSPTPYHLVNYIEEKLINYFNAQQLKLNEKWKIKTGSYYIKKE
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCEEEEEC
GTSLIAFNIDVKKKYEPFLIAAAHTDSPGLKLKIDATEKVSGVFYNHIEVYGSPIISTWI
CCEEEEEEEEECCCCCCEEEEEEECCCCCEEEEEECCHHHCHHEEEEEEECCCCHHHHHH
DRDLSLAGIVYFKKNENIESKLINIENIGIIPNLAIHLNRQINEGFKYNAHDNLTVISST
CCCCCEEEEEEEECCCCHHHHEEEEECCCCCCCEEEEEECHHCCCCEECCCCCEEEEECH
KKAIKDNILEQLGIECENFLSCDLIFTESQPSKIIGTEGEFLASKNLDNKSGCHAIMNSY
HHHHHHHHHHHHCCCCHHCEEEEEEEECCCCCEEECCCCCEEEECCCCCCCHHHHHHHHH
VHTSNDKNKIAVFFDNEEVGSLTSRGADSNFLSEVLERIDIALDLTREEHLIKTNKSFNI
HCCCCCCCEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHEEEEECCCHHEEECCCCEEE
SIDSVHGIHPGYTSKHDPNYQANLGKGVVVKNSANFRYATTSTGFAKLKNLAIKNNIKIQ
EEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCHHHHHHHHHHCCCCEEE
EIIMKANVPSGTTIGPISNARTGIETIDIGTPMWAMHSLRETVSIADHIEAIKLLRAFFE
HEEEECCCCCCCEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGI
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685