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The map label for this gene is htpG [H]

Identifier: 15594905

GI number: 15594905

Start: 571890

End: 573842

Strand: Reverse

Name: htpG [H]

Synonym: BB0560

Alternate gene names: 15594905

Gene position: 573842-571890 (Counterclockwise)

Preceding gene: 15594907

Following gene: 15594898

Centisome position: 63.01

GC content: 27.85

Gene sequence:

>1953_bases
TTGATTCTAATTTTCTATTTTAAACAAATTGCTTTATTTATTATTTTTAGATTATGTTATATTATAAAAAAAGTAAAGAT
TAAATTGAAAAGGAAAAGTTGCATGAAAAAACAATTTGATACAGAAGTAAATGATTTGCTTTATTTAATCATCCACTCTC
TTTACTCCCATAAAGAAATATTTTTAAGAGAATTGATATCAAATGCGTCTGACGCCATTGATAAACTCAAGTTTTTAAGC
TTGACAAACGAAAAATTCAAAAACATTGCTCTAGAACCAAAAATAGAAATATCGTTTGATGATAAAAGCATCCTAATTAA
AGATAATGGAATCGGAATGGATGAACAAGATTTAACTAATCATCTTGGCGTAATTGCAAAATCAGGAACTAAAGAATTTA
TTAACAATTTAAAACAAGATGAAAAAAAATCTGCAAGCCTAATTGGCCAGTTTGGAGTTGGATTTTACAGCGCATTCATA
GTATCAGAAAAAGTAGAAGTTACATCAAAAAAAGCATTAGAAAGCGACGCATATATTTGGTCTAGCGACGGCAAAACAGG
ATATGAAATAGAAAAAGCAAAAAAAGAAGAGTCAGGTACAGAAATAAAGTTATATCTTAATAAAGAAGGCCTTGAATATG
CTAATAAATGGAAAATTCAAGAAATTATCAAAAAATATTCAAATCACATAAATTATCCCATTTATATTAAATACAGCGAA
CCTATAATGAAGGACGGGAAACAAGAGGGAATAGAAGAAAAAGAAGAAAAATTAAATGAAACTACTGCTCTTTGGACAAA
AAATAAAAGCGAAATTAAAGCAGAAGAATACAATGAATTTTATAAAAATACAACCTTTGATTATGAAAATCCATTAATGC
ATATTCATACAAAAGCCGAAGGAAATTTGGAATATACTAATTTATTTTACGTCCCAAGCAAAGCTCCCTATGATTTATAT
TACCCAAACACTAAGCCTGGGGTAAAGCTATTTATAAATAGAATCTTTATTACAGATTCTGAAGGCAGCTTGCTTCCAAA
CTATCTAAGATTTATAAAAGGAATTATAGACTGCCAAGATTTGCCACTCAATGTAAGTAGAGAAATTTTACAGCAAAATA
AAATTTTGTCTAAAATAAAATCATCTTCTGTAAAAAAAATACTAAGCGAGCTTGAAAAGCTAAGTAAAAAAAATCCTGAA
AAATTTTCAGAGTTTTCTAAAGAATTTGGGAGATGCATTAAAGAAGGTGTTTATTCTGACTTTGAAAACAGAGAAAAGCT
TATATCATTAATAAGGTTTAAATCCTCAAGTGTAGATGGGTTTGTGTCTTTTAAAGAGTATAAAGAAAGAATGAATGAGA
GTCAAAAAAGCATTTACTACATAACAGGCGGTAAAGAAAATATATTAAAAGAAAACCCAATAGTAGCTGCTTATAAAGAA
AAAGGATTTGAAATCTTAATCATGGACGATGAACTCGATGAAGCTATTTTAAATCTAATTCCAGAATACGAAGGATTAAA
ACTAAAGGCAATAAATAAAAACGAAACCAGCAATGAATTAAAAGATGAAAATTTCAAAAAAATTGAAGAAGAATTCAAAG
ATACCCTTACAAAAGTAAAAGAAATCCTCAAGGATCATATAAAAGAAGTCAATCTATCAGCAACATTGATAAAAGAGCCT
TCAGCAATAATAATTGATAGCAATGATCCAACTTACCAAATGCAAAAAATCATGCTGTCAATGGGACAAGAAGTAAAAGA
AATAAAACCAATACTTGAATTAAACCCTAATAATAAAATAGTCCAAAATTTAAAAAATCTAGAGCCTGAAAAATTAGAAA
AAATAAGCATTCTCCTTTTTGAAGAAGCTATGTTAACTTCAGGAATGCCCAGCAAAAATCCAGGAAAATTTATAAATATA
ATAAACGAATTTATAGAAAAAGACTTCTTATAA

Upstream 100 bases:

>100_bases
ATTGTAAACAGAAACATTAAAACCGTTATCAGCAATATTTAGAGCTAAATTACTACCCATAACACCAAGTCCATAAATTC
CTACATCCATTGCATTCTCC

Downstream 100 bases:

>100_bases
TTAAAAGTAAAAAGAGAGAGTTTTAAGCTCTCTCTTTTTACTTTTTAACTCGCAACACCAAATCTTTGCCCGCTATAACA
GGCTTTGTTTGAGATATTTT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 650; Mature: 650

Protein sequence:

>650_residues
MILIFYFKQIALFIIFRLCYIIKKVKIKLKRKSCMKKQFDTEVNDLLYLIIHSLYSHKEIFLRELISNASDAIDKLKFLS
LTNEKFKNIALEPKIEISFDDKSILIKDNGIGMDEQDLTNHLGVIAKSGTKEFINNLKQDEKKSASLIGQFGVGFYSAFI
VSEKVEVTSKKALESDAYIWSSDGKTGYEIEKAKKEESGTEIKLYLNKEGLEYANKWKIQEIIKKYSNHINYPIYIKYSE
PIMKDGKQEGIEEKEEKLNETTALWTKNKSEIKAEEYNEFYKNTTFDYENPLMHIHTKAEGNLEYTNLFYVPSKAPYDLY
YPNTKPGVKLFINRIFITDSEGSLLPNYLRFIKGIIDCQDLPLNVSREILQQNKILSKIKSSSVKKILSELEKLSKKNPE
KFSEFSKEFGRCIKEGVYSDFENREKLISLIRFKSSSVDGFVSFKEYKERMNESQKSIYYITGGKENILKENPIVAAYKE
KGFEILIMDDELDEAILNLIPEYEGLKLKAINKNETSNELKDENFKKIEEEFKDTLTKVKEILKDHIKEVNLSATLIKEP
SAIIIDSNDPTYQMQKIMLSMGQEVKEIKPILELNPNNKIVQNLKNLEPEKLEKISILLFEEAMLTSGMPSKNPGKFINI
INEFIEKDFL

Sequences:

>Translated_650_residues
MILIFYFKQIALFIIFRLCYIIKKVKIKLKRKSCMKKQFDTEVNDLLYLIIHSLYSHKEIFLRELISNASDAIDKLKFLS
LTNEKFKNIALEPKIEISFDDKSILIKDNGIGMDEQDLTNHLGVIAKSGTKEFINNLKQDEKKSASLIGQFGVGFYSAFI
VSEKVEVTSKKALESDAYIWSSDGKTGYEIEKAKKEESGTEIKLYLNKEGLEYANKWKIQEIIKKYSNHINYPIYIKYSE
PIMKDGKQEGIEEKEEKLNETTALWTKNKSEIKAEEYNEFYKNTTFDYENPLMHIHTKAEGNLEYTNLFYVPSKAPYDLY
YPNTKPGVKLFINRIFITDSEGSLLPNYLRFIKGIIDCQDLPLNVSREILQQNKILSKIKSSSVKKILSELEKLSKKNPE
KFSEFSKEFGRCIKEGVYSDFENREKLISLIRFKSSSVDGFVSFKEYKERMNESQKSIYYITGGKENILKENPIVAAYKE
KGFEILIMDDELDEAILNLIPEYEGLKLKAINKNETSNELKDENFKKIEEEFKDTLTKVKEILKDHIKEVNLSATLIKEP
SAIIIDSNDPTYQMQKIMLSMGQEVKEIKPILELNPNNKIVQNLKNLEPEKLEKISILLFEEAMLTSGMPSKNPGKFINI
INEFIEKDFL
>Mature_650_residues
MILIFYFKQIALFIIFRLCYIIKKVKIKLKRKSCMKKQFDTEVNDLLYLIIHSLYSHKEIFLRELISNASDAIDKLKFLS
LTNEKFKNIALEPKIEISFDDKSILIKDNGIGMDEQDLTNHLGVIAKSGTKEFINNLKQDEKKSASLIGQFGVGFYSAFI
VSEKVEVTSKKALESDAYIWSSDGKTGYEIEKAKKEESGTEIKLYLNKEGLEYANKWKIQEIIKKYSNHINYPIYIKYSE
PIMKDGKQEGIEEKEEKLNETTALWTKNKSEIKAEEYNEFYKNTTFDYENPLMHIHTKAEGNLEYTNLFYVPSKAPYDLY
YPNTKPGVKLFINRIFITDSEGSLLPNYLRFIKGIIDCQDLPLNVSREILQQNKILSKIKSSSVKKILSELEKLSKKNPE
KFSEFSKEFGRCIKEGVYSDFENREKLISLIRFKSSSVDGFVSFKEYKERMNESQKSIYYITGGKENILKENPIVAAYKE
KGFEILIMDDELDEAILNLIPEYEGLKLKAINKNETSNELKDENFKKIEEEFKDTLTKVKEILKDHIKEVNLSATLIKEP
SAIIIDSNDPTYQMQKIMLSMGQEVKEIKPILELNPNNKIVQNLKNLEPEKLEKISILLFEEAMLTSGMPSKNPGKFINI
INEFIEKDFL

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=666, Percent_Identity=34.3843843843844, Blast_Score=348, Evalue=7e-96,
Organism=Homo sapiens, GI155722983, Length=636, Percent_Identity=28.9308176100629, Blast_Score=325, Evalue=9e-89,
Organism=Homo sapiens, GI20149594, Length=409, Percent_Identity=35.6968215158924, Blast_Score=237, Evalue=3e-62,
Organism=Homo sapiens, GI154146191, Length=409, Percent_Identity=35.9413202933985, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI153792590, Length=409, Percent_Identity=35.6968215158924, Blast_Score=233, Evalue=5e-61,
Organism=Escherichia coli, GI1786679, Length=621, Percent_Identity=41.3848631239936, Blast_Score=496, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI17559162, Length=648, Percent_Identity=36.4197530864198, Blast_Score=379, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17542208, Length=675, Percent_Identity=36.8888888888889, Blast_Score=379, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI115535205, Length=643, Percent_Identity=31.4152410575428, Blast_Score=286, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI115535167, Length=415, Percent_Identity=36.144578313253, Blast_Score=253, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6323840, Length=671, Percent_Identity=36.6616989567809, Blast_Score=393, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6325016, Length=675, Percent_Identity=36.4444444444444, Blast_Score=389, Evalue=1e-108,
Organism=Drosophila melanogaster, GI21357739, Length=687, Percent_Identity=35.2256186317322, Blast_Score=376, Evalue=1e-104,
Organism=Drosophila melanogaster, GI17647529, Length=664, Percent_Identity=35.5421686746988, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24586016, Length=644, Percent_Identity=30.7453416149068, Blast_Score=304, Evalue=1e-82,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 75425; Mature: 75425

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIFYFKQIALFIIFRLCYIIKKVKIKLKRKSCMKKQFDTEVNDLLYLIIHSLYSHKEI
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
FLRELISNASDAIDKLKFLSLTNEKFKNIALEPKIEISFDDKSILIKDNGIGMDEQDLTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEECCCCCCCHHHHHH
HLGVIAKSGTKEFINNLKQDEKKSASLIGQFGVGFYSAFIVSEKVEVTSKKALESDAYIW
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
SSDGKTGYEIEKAKKEESGTEIKLYLNKEGLEYANKWKIQEIIKKYSNHINYPIYIKYSE
ECCCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECC
PIMKDGKQEGIEEKEEKLNETTALWTKNKSEIKAEEYNEFYKNTTFDYENPLMHIHTKAE
HHHHCCHHCCHHHHHHHHHHHHHHEECCHHHCCHHHHHHHHCCCCCCCCCCEEEEEECCC
GNLEYTNLFYVPSKAPYDLYYPNTKPGVKLFINRIFITDSEGSLLPNYLRFIKGIIDCQD
CCEEEEEEEEECCCCCCEEECCCCCCCHHEEEEEEEEECCCCCCCHHHHHHHHHHHCCCC
LPLNVSREILQQNKILSKIKSSSVKKILSELEKLSKKNPEKFSEFSKEFGRCIKEGVYSD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
FENREKLISLIRFKSSSVDGFVSFKEYKERMNESQKSIYYITGGKENILKENPIVAAYKE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEEC
KGFEILIMDDELDEAILNLIPEYEGLKLKAINKNETSNELKDENFKKIEEEFKDTLTKVK
CCCEEEEECCCHHHHHHHHCCCCCCCEEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHH
EILKDHIKEVNLSATLIKEPSAIIIDSNDPTYQMQKIMLSMGQEVKEIKPILELNPNNKI
HHHHHHHHHCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHCHHHHHCCHHHEECCCHHH
VQNLKNLEPEKLEKISILLFEEAMLTSGMPSKNPGKFINIINEFIEKDFL
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILIFYFKQIALFIIFRLCYIIKKVKIKLKRKSCMKKQFDTEVNDLLYLIIHSLYSHKEI
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
FLRELISNASDAIDKLKFLSLTNEKFKNIALEPKIEISFDDKSILIKDNGIGMDEQDLTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEECCCCCCCHHHHHH
HLGVIAKSGTKEFINNLKQDEKKSASLIGQFGVGFYSAFIVSEKVEVTSKKALESDAYIW
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
SSDGKTGYEIEKAKKEESGTEIKLYLNKEGLEYANKWKIQEIIKKYSNHINYPIYIKYSE
ECCCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECC
PIMKDGKQEGIEEKEEKLNETTALWTKNKSEIKAEEYNEFYKNTTFDYENPLMHIHTKAE
HHHHCCHHCCHHHHHHHHHHHHHHEECCHHHCCHHHHHHHHCCCCCCCCCCEEEEEECCC
GNLEYTNLFYVPSKAPYDLYYPNTKPGVKLFINRIFITDSEGSLLPNYLRFIKGIIDCQD
CCEEEEEEEEECCCCCCEEECCCCCCCHHEEEEEEEEECCCCCCCHHHHHHHHHHHCCCC
LPLNVSREILQQNKILSKIKSSSVKKILSELEKLSKKNPEKFSEFSKEFGRCIKEGVYSD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
FENREKLISLIRFKSSSVDGFVSFKEYKERMNESQKSIYYITGGKENILKENPIVAAYKE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEEC
KGFEILIMDDELDEAILNLIPEYEGLKLKAINKNETSNELKDENFKKIEEEFKDTLTKVK
CCCEEEEECCCHHHHHHHHCCCCCCCEEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHH
EILKDHIKEVNLSATLIKEPSAIIIDSNDPTYQMQKIMLSMGQEVKEIKPILELNPNNKI
HHHHHHHHHCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHCHHHHHCCHHHEECCCHHH
VQNLKNLEPEKLEKISILLFEEAMLTSGMPSKNPGKFINIINEFIEKDFL
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA