Click here to switch to the map view.

The map label for this gene is cof [C]

Identifier: 15594766

GI number: 15594766

Start: 441713

End: 442552

Strand: Reverse

Name: cof [C]

Synonym: BB0421

Alternate gene names: 15594766

Gene position: 442552-441713 (Counterclockwise)

Preceding gene: 15594767

Following gene: 15594765

Centisome position: 48.59

GC content: 26.55

Gene sequence:

>840_bases
ATGAATTCTAATTATAAAAGATATAAAATGCTGGTTTTTGACCTTGATGGCACTTTATTGAATAATAACCATGAGATTGC
CTTTTTAACTCTTGAGGTTCTTTTGGCTTTGAAGGAAGATTTTAAAATAATTATTGCAACCGGTAGAAGATTGAGTGAAG
TTAAAAATATAAGGAGCCAATTAAAAGAAATTAGTATTAATGAAAATTATCTTGTAACGGCGAATGGGGCTGAAGTGTTT
TTGCAAGAAAATTTAATTTTTAGATACGCAATGAATTATGACTTAGCAAAAGAAATTCTCAAGATAAATACAGATAATGT
TGATGTTAATCTTTATACTTTTGACACTTGGTATTCTAATGCAGATGTTAAAAGTCCTATTATGAAACATTTTATTAAAG
ATTTGGGCTTAAATGTTATTATTGGAGATTTGACCAAACTAAACGTTGATTCTGTTTCTAAGATTGTTTATTATTGTGAC
GATTTGGCAATTCTTAATAAACTTGACACTGAGATTAAAAGTAAAGATTTCCAGGACACAAGAGTGTTTTTTTCTTCTAA
AGATTTATTAGAGGTTACCAATATTAATGCTAATAAATATAATGCTATTAAAAATATTGCTTTTCTTGAAAGCATTCCAT
TGTGTGATGTTTTAGCTTTTGGAGATAATAATAATGATTATGAAATGCTCAAAAATCTTGGTAAAGGGGTTTTAATGAAA
AATGCCAATGAATTTCTTAAAATTAATTTAGCAAAGAATGAAATAACAAGATTTAGTAATAATGAGGATGGCGTTGCTAG
GTTTTTAATTGATTTTTTTAAGCTTAATATTAAATATTAA

Upstream 100 bases:

>100_bases
AAAAATATAATATTATTAAATTTTATTATTTTATGCTTTAAGAATAATTTATTAAGAATAAATTATTTGTGATAGTATAT
CTTAAAAGAGAGATTTATAT

Downstream 100 bases:

>100_bases
TAATTTGTATTTAAATGTTTAATCCATTTGATTTATTTTTAGCAGGATTTTCTATTTAAAATATAAATTTTTTACTTATA
ATGTATTTTTGAAAATTTAT

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MNSNYKRYKMLVFDLDGTLLNNNHEIAFLTLEVLLALKEDFKIIIATGRRLSEVKNIRSQLKEISINENYLVTANGAEVF
LQENLIFRYAMNYDLAKEILKINTDNVDVNLYTFDTWYSNADVKSPIMKHFIKDLGLNVIIGDLTKLNVDSVSKIVYYCD
DLAILNKLDTEIKSKDFQDTRVFFSSKDLLEVTNINANKYNAIKNIAFLESIPLCDVLAFGDNNNDYEMLKNLGKGVLMK
NANEFLKINLAKNEITRFSNNEDGVARFLIDFFKLNIKY

Sequences:

>Translated_279_residues
MNSNYKRYKMLVFDLDGTLLNNNHEIAFLTLEVLLALKEDFKIIIATGRRLSEVKNIRSQLKEISINENYLVTANGAEVF
LQENLIFRYAMNYDLAKEILKINTDNVDVNLYTFDTWYSNADVKSPIMKHFIKDLGLNVIIGDLTKLNVDSVSKIVYYCD
DLAILNKLDTEIKSKDFQDTRVFFSSKDLLEVTNINANKYNAIKNIAFLESIPLCDVLAFGDNNNDYEMLKNLGKGVLMK
NANEFLKINLAKNEITRFSNNEDGVARFLIDFFKLNIKY
>Mature_279_residues
MNSNYKRYKMLVFDLDGTLLNNNHEIAFLTLEVLLALKEDFKIIIATGRRLSEVKNIRSQLKEISINENYLVTANGAEVF
LQENLIFRYAMNYDLAKEILKINTDNVDVNLYTFDTWYSNADVKSPIMKHFIKDLGLNVIIGDLTKLNVDSVSKIVYYCD
DLAILNKLDTEIKSKDFQDTRVFFSSKDLLEVTNINANKYNAIKNIAFLESIPLCDVLAFGDNNNDYEMLKNLGKGVLMK
NANEFLKINLAKNEITRFSNNEDGVARFLIDFFKLNIKY

Specific function: Unknown

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI48994981, Length=266, Percent_Identity=32.7067669172932, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI87081741, Length=268, Percent_Identity=29.8507462686567, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI2367265, Length=280, Percent_Identity=27.1428571428571, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: NA

Molecular weight: Translated: 32154; Mature: 32154

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSNYKRYKMLVFDLDGTLLNNNHEIAFLTLEVLLALKEDFKIIIATGRRLSEVKNIRSQ
CCCCCEEEEEEEEECCCEEECCCCCEEEHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHH
LKEISINENYLVTANGAEVFLQENLIFRYAMNYDLAKEILKINTDNVDVNLYTFDTWYSN
HHHCCCCCCEEEEECCCEEEEECCEEEEEECCHHHHHHHHHCCCCCEEEEEEEEEEEECC
ADVKSPIMKHFIKDLGLNVIIGDLTKLNVDSVSKIVYYCDDLAILNKLDTEIKSKDFQDT
CCCCHHHHHHHHHHCCCEEEEECCEECCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHH
RVFFSSKDLLEVTNINANKYNAIKNIAFLESIPLCDVLAFGDNNNDYEMLKNLGKGVLMK
EEEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCEEEC
NANEFLKINLAKNEITRFSNNEDGVARFLIDFFKLNIKY
CCCCEEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNSNYKRYKMLVFDLDGTLLNNNHEIAFLTLEVLLALKEDFKIIIATGRRLSEVKNIRSQ
CCCCCEEEEEEEEECCCEEECCCCCEEEHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHH
LKEISINENYLVTANGAEVFLQENLIFRYAMNYDLAKEILKINTDNVDVNLYTFDTWYSN
HHHCCCCCCEEEEECCCEEEEECCEEEEEECCHHHHHHHHHCCCCCEEEEEEEEEEEECC
ADVKSPIMKHFIKDLGLNVIIGDLTKLNVDSVSKIVYYCDDLAILNKLDTEIKSKDFQDT
CCCCHHHHHHHHHHCCCEEEEECCEECCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHH
RVFFSSKDLLEVTNINANKYNAIKNIAFLESIPLCDVLAFGDNNNDYEMLKNLGKGVLMK
EEEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCEEEC
NANEFLKINLAKNEITRFSNNEDGVARFLIDFFKLNIKY
CCCCEEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]