Click here to switch to the map view.

The map label for this gene is rpoC [H]

Identifier: 15594733

GI number: 15594733

Start: 397544

End: 401677

Strand: Reverse

Name: rpoC [H]

Synonym: BB0388

Alternate gene names: 15594733

Gene position: 401677-397544 (Counterclockwise)

Preceding gene: 15594734

Following gene: 15594732

Centisome position: 44.11

GC content: 33.36

Gene sequence:

>4134_bases
ATGAAAGAGATAAAAGATTTTGAAAGAATAAAAATTAAAATAGCGTCTCCCGATCAAATTAGAAATTGGTCTTATGGAGA
GGTTAAAAAGTCCGAAACTATTAATTATAGAACTTTAAGACCCGAAAAAGATGGGCTTTTTTGTGAAAGGATTTTTGGTA
CTACAAAGGAATGGGAATGTTATTGTGGTAAATTTAAATCGGTCAGATATAAAGGTATTATTTGTGATCGTTGTAATGTA
GAGGTTACCCATTTTAAGGTTAGACGTGAAAGAATGGGGCATATTGAGCTAGCAGCCCCAGTTGCTCATATTTGGTATTA
CAAATATATACCCTCTAGGATTGGGCTTTTGCTTGATATTACAGCATCTAGTTTGAATTCTATTCTTTATTATGAAAAAT
ATGTAGTAATTGAACCGGGCGATACTGATCTTAAAAAAATGCAGCTTTTAAATGAAGATGAGTACATAGAAGCTAGAGAG
CGATATGGTATGTCTTTTAATGCTTCAATGGGGGCTGAGGCTATTAAAACTCTTCTTGAAAATCTTGATCTTGATGAGCT
TTCGTCTAAGCTTAGAATTCAAATGATAGATAAAGATGATAAAACTGATAAGAAACTCTTAAGACGTCTTGAAATTATTG
AGAATTTTAAAATTTCTGGCAATAAGCCAGAGTGGATGATTATGGAAGTTCTTCCTGTTATTCCCCCAGAGATTAGGCCA
ATGGTTCAGCTTGATGGGGGGCGCTTTGCAACATCTGATCTTAATGATCTTTATAGAAGAGTCATAAATAGAAATAATCG
TTTAAGAAAGTTGCTTCTTCTTAATGCGCCAGAGATTATTGTGAGAAACGAAAAAAGAATGCTTCAAGAATCAGTAGACT
CTCTTTTTGACAATTCTCATAAAAGAAAGGTTGTCAAAGGTTCATCTAGTAGGCCTCTCAAGTCGCTTTCCGATGCATTA
AAAGGTAAGCAGGGAAGGTTTAGGCAAAATCTTCTTGGTAAAAGAGTAGATTATTCTGGTCGTTCTGTTATTGTTGTTGG
ACCTGAGCTTAAGCTACATCAATGTGGATTGCCTGCAAAAATGGCCCTTGAGCTTTTTAAGCCTTTTGTGATAAGAAGAC
TGATTGAGAGTGAAGCTGTTTTTAATATCAAAAGAGCAAAGAATTTAATAGAGCAAGAAGTAGATGAGGTGTGGCAAATT
TTAGATCTTGTTATCAAAGAGCATCCTATTCTTTTAAATAGGGCACCCACTCTTCATAGACTTGGAATTCAAGCTTTTGA
ACCTGTGTTAGTTGAGGGTAAGGCAATAAAATTACATCCTCTTGTTTGTCATGCATACAATGCCGATTTTGATGGTGATC
AAATGGCGGTACATGTGCCTCTTACTCCGGCAGCACAAGCTGAAAGTTGGGCTTTAATGCTTTCAACAAATAATCTTTTA
AATCCTGCCAATGGGCATCCTATTGTTTTTCCATCCCAAGATATTGTTTTGGGCCTATATTATTTAACTATGGAAAAAAA
GAATGTTGTTGGAGAAGGTAAAAAGTTTTTAAACTTTAACAATGTTATTCTTGCCATAAATAATAGGAGTCTGGATTACA
ATGCTTCTATTTATGTAAAAATTCATGGTGAGTACAAAAAAACTACGGCCGGTAGGGTTATATTTAATGAGGCTTTGCCC
AAGGGAATTGAATTTGTAAATAAAACCCTTAGTGATTTGGAGCTACAAATTTTAATATCAAAAGTTTATGTAGTTCATGG
TTCTTCTATCGTAATTGAAATGCTTGACATCATCAAGGAACTTGGTTTTAGGTATGCCACTAAGTTTGGATGCACAATTA
GTATGAGCGATATTATTGTTCCTGATGAAAAAAGAACTTATGTAGAAAGGGCCAATAAAGAGATTGCTAAGATTCAAAAT
GATTATGCTAAAGGTGTTATTACTGGCGAAGAGCGTTATAACAATGTAGTTTCTGTTTGGTTAAAGACCAATGAAGAACT
TACTAATAAGATGATGGAAATTTTAAAGAAAGATAGAGATGGATTTAATGTTATATATATGATGGCAGATTCTGGTGCTA
GGGGTAGTAGGAATCAAATAAGACAGCTTGCTGGTATGAGAGGATTGATGGCAAAAACTTCTGGGGATATTATTGAGCTT
CCAATTATTTCTAACTTTAAAGAAGGTCTTTCTGTGATAGAGTTTTTTATATCTACAAATGGAGCAAGAAAAGGTCTAGC
AGATACTGCTCTTAAGACCGCTGATGCTGGATATTTAACTCGAAGATTAGTAGACATTGCTCAAGATGTTGTTGTTAGAA
TAGAGGATTGTGGAACTATAAATGGAATAAAAGTTGAGACTGTAAAAAATGGTGAAGAAATATTAGAATCTTTGAAAGAA
AAAGCTGTTGGGAGTTATTCTATTGAAAGAATAAAAAATCCAATTACTGGCGAGATTGTTTTAGATGCAAATGAAGAAAT
CTCAGAAGCTAAAATAGAATTATTAGAGAAAATTGGTATTGAAAAACTTGTTATTAGATCTGTTTTAACGTGTGAAGCTG
AGCATGGCGTTTGTCAAAAATGTTATGGTAGAGACTTTTCTAAGAACAAACCTGTTAATATTGGGGAGGCTGTGGGAATA
ATTGCTGCTCAGTCCATAGGTCAACCGGGTACTCAATTAACCATGAGAACTTTTCATATTGGTGGAGTTGCTCAGGCTGG
CAGTGAGGATGATAAAATATCTTTAAAGAATGCCTTCATACTTAATGGCATAGAAGGTTTTAATGTTAGAGTTGATAATG
GAATTCTTTTCACAAGAAAAGGAACTTTAAAAATAATCAATGTTTTTTATGAGGAAAAAATTAAGAACATAAAAGAGATT
AAAGTTTTAGATTCTCAAAGAGTAATAAAAGGAATTCCTTTGTTTATTGATAAAAAGGGCTCAGAGATTCTCTCTTCTTA
CATTGGTTATGTTAAATTAAGAGACGATAATTTTTTCATAGTGTCAGAAGAGCAAGAAGTTTCCTTGAAAGCGGGTACAA
AGCTTGAAATAGAGGTTGGTGATTATGTTGAATCAGGCAAAGTTATTGGTACATTTGATCCATTTGCAGAGCCTATTATT
GCAGAGGTTAAGGGTAAAATTAAATTTAAGGATATTATTTTAGGAACTACTCTTAAAGAGGAAATAAATACTGAAACAGG
CAATGTTGAAAAAAGAATTACAGATAATGTTTTTGAATCTCTTGATCCTAGAATTTTTATTATTGATAGTAGTGGTATGG
AGGTTGCATCTTATGTATTACCAGGTGATGCTTATCTTCAAGTTGAAGATGGCCAGAGTATTAACATAGGAGATATTATT
GCGAAACTTTCTAAAGGTTCTGAAAAAACTCAAGATATTACAGGGGGATTGCCTCGTGTTAATGATCTTTTTGAGACAAG
AATTCCTAAGAATTTAACTGAAATGGCTAAAGTAAGCGGAATTGTACAATTTAAATCAATTCAAAAAGGTAAAAGGCTTA
TTAATATTTTAGATGAGTATGGGGTTGAACATAAGCATTATATTCCAGCTGGAAAACATCTTTTGGTTAGAGATGGAGAT
GTTGTAAAAGCAGGAGATATGCTTTGTGATGGTAGAATTAATCCTCATGATGTGCTTGAAATTTTAGGTGGGATTAGTTT
ACAAGAATTTCTGTTGGCAGAAATTCAGGATGTTTATCGAAAACAGGGTGTTAGCATTAATGACAAACATATTGGTGTGA
TAATCAAGCAAATGATGAAAAAAGTTAAGATTGTTGCAGTTGGTGATACTAATTTTGTTTATGGGCAAAAGGTAGATAAG
CACACTTTTTATGAGCAAAATAGAAAAGTAATCGAACAAGGTGGTGAGCCAGCAATAGCAAGTCCAATTCTTATAGGAGT
AACTAAAACGTCTCTTAATATAGATTCTTTTATTTCCGCAGCTTCTTTCCAGGAAACAACAAAAGTATTAACAGATGCTT
CTATTGCTGGAAAAATAGATGATCTTAGGGGATTAAAAGAAAATGTTGTAATTGGACATTTAATTCCTACTGGAACTGGT
ATGGGTCTTTATAAAAAAATTAAAGTTAGTGAAAATATCGATTCTGAAGTTTAA

Upstream 100 bases:

>100_bases
TGGACTTGATTTGTCAATTTATGATGATGCTGGGAATCAGGTTCCTTTGACAGAAAAAGAAGAAGAATTGATTAATAAAA
GCTAGGTTTTTGGAGTTTTT

Downstream 100 bases:

>100_bases
CTTGAAAATAAGTGATATATTTGCTACCATTTTATTAATAGTTTCAAGAAAAGGAGAGCGTTGATAAATGCCTACAATTA
ATCAGTTAATTAGAAAGCCT

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1377; Mature: 1377

Protein sequence:

>1377_residues
MKEIKDFERIKIKIASPDQIRNWSYGEVKKSETINYRTLRPEKDGLFCERIFGTTKEWECYCGKFKSVRYKGIICDRCNV
EVTHFKVRRERMGHIELAAPVAHIWYYKYIPSRIGLLLDITASSLNSILYYEKYVVIEPGDTDLKKMQLLNEDEYIEARE
RYGMSFNASMGAEAIKTLLENLDLDELSSKLRIQMIDKDDKTDKKLLRRLEIIENFKISGNKPEWMIMEVLPVIPPEIRP
MVQLDGGRFATSDLNDLYRRVINRNNRLRKLLLLNAPEIIVRNEKRMLQESVDSLFDNSHKRKVVKGSSSRPLKSLSDAL
KGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPAKMALELFKPFVIRRLIESEAVFNIKRAKNLIEQEVDEVWQI
LDLVIKEHPILLNRAPTLHRLGIQAFEPVLVEGKAIKLHPLVCHAYNADFDGDQMAVHVPLTPAAQAESWALMLSTNNLL
NPANGHPIVFPSQDIVLGLYYLTMEKKNVVGEGKKFLNFNNVILAINNRSLDYNASIYVKIHGEYKKTTAGRVIFNEALP
KGIEFVNKTLSDLELQILISKVYVVHGSSIVIEMLDIIKELGFRYATKFGCTISMSDIIVPDEKRTYVERANKEIAKIQN
DYAKGVITGEERYNNVVSVWLKTNEELTNKMMEILKKDRDGFNVIYMMADSGARGSRNQIRQLAGMRGLMAKTSGDIIEL
PIISNFKEGLSVIEFFISTNGARKGLADTALKTADAGYLTRRLVDIAQDVVVRIEDCGTINGIKVETVKNGEEILESLKE
KAVGSYSIERIKNPITGEIVLDANEEISEAKIELLEKIGIEKLVIRSVLTCEAEHGVCQKCYGRDFSKNKPVNIGEAVGI
IAAQSIGQPGTQLTMRTFHIGGVAQAGSEDDKISLKNAFILNGIEGFNVRVDNGILFTRKGTLKIINVFYEEKIKNIKEI
KVLDSQRVIKGIPLFIDKKGSEILSSYIGYVKLRDDNFFIVSEEQEVSLKAGTKLEIEVGDYVESGKVIGTFDPFAEPII
AEVKGKIKFKDIILGTTLKEEINTETGNVEKRITDNVFESLDPRIFIIDSSGMEVASYVLPGDAYLQVEDGQSINIGDII
AKLSKGSEKTQDITGGLPRVNDLFETRIPKNLTEMAKVSGIVQFKSIQKGKRLINILDEYGVEHKHYIPAGKHLLVRDGD
VVKAGDMLCDGRINPHDVLEILGGISLQEFLLAEIQDVYRKQGVSINDKHIGVIIKQMMKKVKIVAVGDTNFVYGQKVDK
HTFYEQNRKVIEQGGEPAIASPILIGVTKTSLNIDSFISAASFQETTKVLTDASIAGKIDDLRGLKENVVIGHLIPTGTG
MGLYKKIKVSENIDSEV

Sequences:

>Translated_1377_residues
MKEIKDFERIKIKIASPDQIRNWSYGEVKKSETINYRTLRPEKDGLFCERIFGTTKEWECYCGKFKSVRYKGIICDRCNV
EVTHFKVRRERMGHIELAAPVAHIWYYKYIPSRIGLLLDITASSLNSILYYEKYVVIEPGDTDLKKMQLLNEDEYIEARE
RYGMSFNASMGAEAIKTLLENLDLDELSSKLRIQMIDKDDKTDKKLLRRLEIIENFKISGNKPEWMIMEVLPVIPPEIRP
MVQLDGGRFATSDLNDLYRRVINRNNRLRKLLLLNAPEIIVRNEKRMLQESVDSLFDNSHKRKVVKGSSSRPLKSLSDAL
KGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPAKMALELFKPFVIRRLIESEAVFNIKRAKNLIEQEVDEVWQI
LDLVIKEHPILLNRAPTLHRLGIQAFEPVLVEGKAIKLHPLVCHAYNADFDGDQMAVHVPLTPAAQAESWALMLSTNNLL
NPANGHPIVFPSQDIVLGLYYLTMEKKNVVGEGKKFLNFNNVILAINNRSLDYNASIYVKIHGEYKKTTAGRVIFNEALP
KGIEFVNKTLSDLELQILISKVYVVHGSSIVIEMLDIIKELGFRYATKFGCTISMSDIIVPDEKRTYVERANKEIAKIQN
DYAKGVITGEERYNNVVSVWLKTNEELTNKMMEILKKDRDGFNVIYMMADSGARGSRNQIRQLAGMRGLMAKTSGDIIEL
PIISNFKEGLSVIEFFISTNGARKGLADTALKTADAGYLTRRLVDIAQDVVVRIEDCGTINGIKVETVKNGEEILESLKE
KAVGSYSIERIKNPITGEIVLDANEEISEAKIELLEKIGIEKLVIRSVLTCEAEHGVCQKCYGRDFSKNKPVNIGEAVGI
IAAQSIGQPGTQLTMRTFHIGGVAQAGSEDDKISLKNAFILNGIEGFNVRVDNGILFTRKGTLKIINVFYEEKIKNIKEI
KVLDSQRVIKGIPLFIDKKGSEILSSYIGYVKLRDDNFFIVSEEQEVSLKAGTKLEIEVGDYVESGKVIGTFDPFAEPII
AEVKGKIKFKDIILGTTLKEEINTETGNVEKRITDNVFESLDPRIFIIDSSGMEVASYVLPGDAYLQVEDGQSINIGDII
AKLSKGSEKTQDITGGLPRVNDLFETRIPKNLTEMAKVSGIVQFKSIQKGKRLINILDEYGVEHKHYIPAGKHLLVRDGD
VVKAGDMLCDGRINPHDVLEILGGISLQEFLLAEIQDVYRKQGVSINDKHIGVIIKQMMKKVKIVAVGDTNFVYGQKVDK
HTFYEQNRKVIEQGGEPAIASPILIGVTKTSLNIDSFISAASFQETTKVLTDASIAGKIDDLRGLKENVVIGHLIPTGTG
MGLYKKIKVSENIDSEV
>Mature_1377_residues
MKEIKDFERIKIKIASPDQIRNWSYGEVKKSETINYRTLRPEKDGLFCERIFGTTKEWECYCGKFKSVRYKGIICDRCNV
EVTHFKVRRERMGHIELAAPVAHIWYYKYIPSRIGLLLDITASSLNSILYYEKYVVIEPGDTDLKKMQLLNEDEYIEARE
RYGMSFNASMGAEAIKTLLENLDLDELSSKLRIQMIDKDDKTDKKLLRRLEIIENFKISGNKPEWMIMEVLPVIPPEIRP
MVQLDGGRFATSDLNDLYRRVINRNNRLRKLLLLNAPEIIVRNEKRMLQESVDSLFDNSHKRKVVKGSSSRPLKSLSDAL
KGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPAKMALELFKPFVIRRLIESEAVFNIKRAKNLIEQEVDEVWQI
LDLVIKEHPILLNRAPTLHRLGIQAFEPVLVEGKAIKLHPLVCHAYNADFDGDQMAVHVPLTPAAQAESWALMLSTNNLL
NPANGHPIVFPSQDIVLGLYYLTMEKKNVVGEGKKFLNFNNVILAINNRSLDYNASIYVKIHGEYKKTTAGRVIFNEALP
KGIEFVNKTLSDLELQILISKVYVVHGSSIVIEMLDIIKELGFRYATKFGCTISMSDIIVPDEKRTYVERANKEIAKIQN
DYAKGVITGEERYNNVVSVWLKTNEELTNKMMEILKKDRDGFNVIYMMADSGARGSRNQIRQLAGMRGLMAKTSGDIIEL
PIISNFKEGLSVIEFFISTNGARKGLADTALKTADAGYLTRRLVDIAQDVVVRIEDCGTINGIKVETVKNGEEILESLKE
KAVGSYSIERIKNPITGEIVLDANEEISEAKIELLEKIGIEKLVIRSVLTCEAEHGVCQKCYGRDFSKNKPVNIGEAVGI
IAAQSIGQPGTQLTMRTFHIGGVAQAGSEDDKISLKNAFILNGIEGFNVRVDNGILFTRKGTLKIINVFYEEKIKNIKEI
KVLDSQRVIKGIPLFIDKKGSEILSSYIGYVKLRDDNFFIVSEEQEVSLKAGTKLEIEVGDYVESGKVIGTFDPFAEPII
AEVKGKIKFKDIILGTTLKEEINTETGNVEKRITDNVFESLDPRIFIIDSSGMEVASYVLPGDAYLQVEDGQSINIGDII
AKLSKGSEKTQDITGGLPRVNDLFETRIPKNLTEMAKVSGIVQFKSIQKGKRLINILDEYGVEHKHYIPAGKHLLVRDGD
VVKAGDMLCDGRINPHDVLEILGGISLQEFLLAEIQDVYRKQGVSINDKHIGVIIKQMMKKVKIVAVGDTNFVYGQKVDK
HTFYEQNRKVIEQGGEPAIASPILIGVTKTSLNIDSFISAASFQETTKVLTDASIAGKIDDLRGLKENVVIGHLIPTGTG
MGLYKKIKVSENIDSEV

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=936, Percent_Identity=25.4273504273504, Blast_Score=174, Evalue=7e-43,
Organism=Homo sapiens, GI39725938, Length=316, Percent_Identity=31.0126582278481, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI103471997, Length=245, Percent_Identity=29.3877551020408, Blast_Score=93, Evalue=2e-18,
Organism=Escherichia coli, GI2367335, Length=1402, Percent_Identity=49.0727532097004, Blast_Score=1332, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=678, Percent_Identity=26.5486725663717, Blast_Score=166, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI25145495, Length=310, Percent_Identity=31.9354838709677, Blast_Score=140, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6320061, Length=876, Percent_Identity=23.5159817351598, Blast_Score=168, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6324690, Length=669, Percent_Identity=25.1121076233184, Blast_Score=160, Evalue=9e-40,
Organism=Drosophila melanogaster, GI281360912, Length=826, Percent_Identity=26.7554479418886, Blast_Score=187, Evalue=4e-47,
Organism=Drosophila melanogaster, GI17530899, Length=924, Percent_Identity=24.8917748917749, Blast_Score=177, Evalue=6e-44,
Organism=Drosophila melanogaster, GI17647875, Length=744, Percent_Identity=23.3870967741935, Blast_Score=119, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 154660; Mature: 154660

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIKDFERIKIKIASPDQIRNWSYGEVKKSETINYRTLRPEKDGLFCERIFGTTKEWEC
CCCCCCCEEEEEEECCCHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCHHH
YCGKFKSVRYKGIICDRCNVEVTHFKVRRERMGHIELAAPVAHIWYYKYIPSRIGLLLDI
HHCCCCCEEEEEEEECCCCEEEEHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCEEEEE
TASSLNSILYYEKYVVIEPGDTDLKKMQLLNEDEYIEARERYGMSFNASMGAEAIKTLLE
CHHHHHHEEEEEEEEEECCCCCCHHHHHHCCCCHHHHHHHHCCCEECCCCCHHHHHHHHH
NLDLDELSSKLRIQMIDKDDKTDKKLLRRLEIIENFKISGNKPEWMIMEVLPVIPPEIRP
CCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHCCCCCCCE
MVQLDGGRFATSDLNDLYRRVINRNNRLRKLLLLNAPEIIVRNEKRMLQESVDSLFDNSH
EEEECCCEEECCCHHHHHHHHHCCCCCEEEEEEECCCHHEEECHHHHHHHHHHHHHCCCC
KRKVVKGSSSRPLKSLSDALKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPAK
CCEEECCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCCCEEECCCCCHH
MALELFKPFVIRRLIESEAVFNIKRAKNLIEQEVDEVWQILDLVIKEHPILLNRAPTLHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHH
LGIQAFEPVLVEGKAIKLHPLVCHAYNADFDGDQMAVHVPLTPAAQAESWALMLSTNNLL
HCHHHCCCEEECCCEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCC
NPANGHPIVFPSQDIVLGLYYLTMEKKNVVGEGKKFLNFNNVILAINNRSLDYNASIYVK
CCCCCCEEEECCCCCEEEEEEEEEECCCCCCCCCCEEEECCEEEEEECCCCCCCCEEEEE
IHGEYKKTTAGRVIFNEALPKGIEFVNKTLSDLELQILISKVYVVHGSSIVIEMLDIIKE
EECCCCCCCCCEEEEHHHCHHHHHHHHHHHHHHHHHEEEEEEEEEECCHHHHHHHHHHHH
LGFRYATKFGCTISMSDIIVPDEKRTYVERANKEIAKIQNDYAKGVITGEERYNNVVSVW
HCHHHHHHCCCEEEECCEECCCCHHHHHHHHHHHHHHHHHHHHCCEEECHHHCCCEEEEE
LKTNEELTNKMMEILKKDRDGFNVIYMMADSGARGSRNQIRQLAGMRGLMAKTSGDIIEL
EECCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEE
PIISNFKEGLSVIEFFISTNGARKGLADTALKTADAGYLTRRLVDIAQDVVVRIEDCGTI
CCHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHEEEECCCCC
NGIKVETVKNGEEILESLKEKAVGSYSIERIKNPITGEIVLDANEEISEAKIELLEKIGI
CCEEEEEECCHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCH
EKLVIRSVLTCEAEHGVCQKCYGRDFSKNKPVNIGEAVGIIAAQSIGQPGTQLTMRTFHI
HHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEE
GGVAQAGSEDDKISLKNAFILNGIEGFNVRVDNGILFTRKGTLKIINVFYEEKIKNIKEI
CCCCCCCCCCCCEEECCEEEEECCCCCEEEECCCEEEEECCCEEHHHHHHHHHHCCHHHE
KVLDSQRVIKGIPLFIDKKGSEILSSYIGYVKLRDDNFFIVSEEQEVSLKAGTKLEIEVG
EECCCHHHHCCCCEEEECCCHHHHHHHCCEEEEECCCEEEEECCCCEEEECCCEEEEEEC
DYVESGKVIGTFDPFAEPIIAEVKGKIKFKDIILGTTLKEEINTETGNVEKRITDNVFES
CCCCCCCEEECCCHHHHHHHHHHCCCEEEEEEEECCHHHHHHCCCCCCCHHHHHHHHHHH
LDPRIFIIDSSGMEVASYVLPGDAYLQVEDGQSINIGDIIAKLSKGSEKTQDITGGLPRV
CCCEEEEEECCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCH
NDLFETRIPKNLTEMAKVSGIVQFKSIQKGKRLINILDEYGVEHKHYIPAGKHLLVRDGD
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCC
VVKAGDMLCDGRINPHDVLEILGGISLQEFLLAEIQDVYRKQGVSINDKHIGVIIKQMMK
EEECCCEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KVKIVAVGDTNFVYGQKVDKHTFYEQNRKVIEQGGEPAIASPILIGVTKTSLNIDSFISA
HEEEEEECCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHH
ASFQETTKVLTDASIAGKIDDLRGLKENVVIGHLIPTGTGMGLYKKIKVSENIDSEV
HHHHHHHHHHHCCHHHCCCHHHCCCHHCEEEEEEECCCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MKEIKDFERIKIKIASPDQIRNWSYGEVKKSETINYRTLRPEKDGLFCERIFGTTKEWEC
CCCCCCCEEEEEEECCCHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCHHH
YCGKFKSVRYKGIICDRCNVEVTHFKVRRERMGHIELAAPVAHIWYYKYIPSRIGLLLDI
HHCCCCCEEEEEEEECCCCEEEEHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCEEEEE
TASSLNSILYYEKYVVIEPGDTDLKKMQLLNEDEYIEARERYGMSFNASMGAEAIKTLLE
CHHHHHHEEEEEEEEEECCCCCCHHHHHHCCCCHHHHHHHHCCCEECCCCCHHHHHHHHH
NLDLDELSSKLRIQMIDKDDKTDKKLLRRLEIIENFKISGNKPEWMIMEVLPVIPPEIRP
CCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHCCCCCCCE
MVQLDGGRFATSDLNDLYRRVINRNNRLRKLLLLNAPEIIVRNEKRMLQESVDSLFDNSH
EEEECCCEEECCCHHHHHHHHHCCCCCEEEEEEECCCHHEEECHHHHHHHHHHHHHCCCC
KRKVVKGSSSRPLKSLSDALKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPAK
CCEEECCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCCCEEECCCCCHH
MALELFKPFVIRRLIESEAVFNIKRAKNLIEQEVDEVWQILDLVIKEHPILLNRAPTLHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHH
LGIQAFEPVLVEGKAIKLHPLVCHAYNADFDGDQMAVHVPLTPAAQAESWALMLSTNNLL
HCHHHCCCEEECCCEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCC
NPANGHPIVFPSQDIVLGLYYLTMEKKNVVGEGKKFLNFNNVILAINNRSLDYNASIYVK
CCCCCCEEEECCCCCEEEEEEEEEECCCCCCCCCCEEEECCEEEEEECCCCCCCCEEEEE
IHGEYKKTTAGRVIFNEALPKGIEFVNKTLSDLELQILISKVYVVHGSSIVIEMLDIIKE
EECCCCCCCCCEEEEHHHCHHHHHHHHHHHHHHHHHEEEEEEEEEECCHHHHHHHHHHHH
LGFRYATKFGCTISMSDIIVPDEKRTYVERANKEIAKIQNDYAKGVITGEERYNNVVSVW
HCHHHHHHCCCEEEECCEECCCCHHHHHHHHHHHHHHHHHHHHCCEEECHHHCCCEEEEE
LKTNEELTNKMMEILKKDRDGFNVIYMMADSGARGSRNQIRQLAGMRGLMAKTSGDIIEL
EECCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEE
PIISNFKEGLSVIEFFISTNGARKGLADTALKTADAGYLTRRLVDIAQDVVVRIEDCGTI
CCHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHEEEECCCCC
NGIKVETVKNGEEILESLKEKAVGSYSIERIKNPITGEIVLDANEEISEAKIELLEKIGI
CCEEEEEECCHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCH
EKLVIRSVLTCEAEHGVCQKCYGRDFSKNKPVNIGEAVGIIAAQSIGQPGTQLTMRTFHI
HHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEE
GGVAQAGSEDDKISLKNAFILNGIEGFNVRVDNGILFTRKGTLKIINVFYEEKIKNIKEI
CCCCCCCCCCCCEEECCEEEEECCCCCEEEECCCEEEEECCCEEHHHHHHHHHHCCHHHE
KVLDSQRVIKGIPLFIDKKGSEILSSYIGYVKLRDDNFFIVSEEQEVSLKAGTKLEIEVG
EECCCHHHHCCCCEEEECCCHHHHHHHCCEEEEECCCEEEEECCCCEEEECCCEEEEEEC
DYVESGKVIGTFDPFAEPIIAEVKGKIKFKDIILGTTLKEEINTETGNVEKRITDNVFES
CCCCCCCEEECCCHHHHHHHHHHCCCEEEEEEEECCHHHHHHCCCCCCCHHHHHHHHHHH
LDPRIFIIDSSGMEVASYVLPGDAYLQVEDGQSINIGDIIAKLSKGSEKTQDITGGLPRV
CCCEEEEEECCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCH
NDLFETRIPKNLTEMAKVSGIVQFKSIQKGKRLINILDEYGVEHKHYIPAGKHLLVRDGD
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCC
VVKAGDMLCDGRINPHDVLEILGGISLQEFLLAEIQDVYRKQGVSINDKHIGVIIKQMMK
EEECCCEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KVKIVAVGDTNFVYGQKVDKHTFYEQNRKVIEQGGEPAIASPILIGVTKTSLNIDSFISA
HEEEEEECCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHH
ASFQETTKVLTDASIAGKIDDLRGLKENVVIGHLIPTGTGMGLYKKIKVSENIDSEV
HHHHHHHHHHHCCHHHCCCHHHCCCHHCEEEEEEECCCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA