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The map label for this gene is gufA [H]

Identifier: 15594564

GI number: 15594564

Start: 223964

End: 224785

Strand: Reverse

Name: gufA [H]

Synonym: BB0219

Alternate gene names: 15594564

Gene position: 224785-223964 (Counterclockwise)

Preceding gene: 15594565

Following gene: 15594559

Centisome position: 24.68

GC content: 35.28

Gene sequence:

>822_bases
ATGATAAAATCAATTTTAGATTATTTATTAACTTTGCATCCTGTATTATTGGGACTTTTAGGTTCTACTTTCACTTGGTT
TACTACAGCTTTTGGAGCAGCAGCAGTTTTTTTCTTTAGAAAGGTAGATAATAAAATAATGGACGCTATGCTTGGTTTTT
CAGCTGGCATTATGATAGCGGCCAGTTTTTTTTCGCTTATTCAGCCTGCTATAGAAAGAGCTGAAGAGCTTGGATACATT
ACTTGGGTGCCGGCTGTTTTTGGATTTCTTGTTGGGGCATTTTTTATATATATTGTAGATGTATTTGTTCCAGATCTGGA
TAAACTTACTTTTATTGATGAAGACTTAACTAAACATGGTAAAAAAGATTTTTTACTCTTTACTGCTGTTACTTTACATA
ATTTTCCAGAAGGATTGGCTGTTGGAGTTGCTTTTGGAGCCTTGGCGTCTAATCCAGATATTCAAACTTTAGTTGGGGCT
ATGCTTCTTACGCTTGGTATTGGTATTCAAAATATTCCCGAAGGAGCAGCTATTTCTCTGCCTTTAAGAAGAGGTAATGT
TGCTTTGGCAAAATGCTTTAACTATGGCCAAATGTCAGGATTGGTAGAAATTGTGGGGGGGCTTATGGGTGCTTATGCGG
TTTATTCTTTTACTCGAATTTTACCTTTTGCTTTGGCTTTTTCTGCAGGAGCTATGATTTATGTGTCAATTGAACAATTA
ATACCTGAAGCTAAGAGAAAAGACATTGACAATAAAGTGCCAAGTATATTTGGTGTTATTGGTTTTACATTAATGATGTT
TCTCGATGTTTCACTAGGTTAA

Upstream 100 bases:

>100_bases
AAAGAACAATCCTCATCTTCAGGTATAAGAAGAATAAAAGCTATTTTGATTGATGAGTAAATTACTTATTATTTGTTGAT
TTGTTTTAATAGGAGGCTTT

Downstream 100 bases:

>100_bases
AATTATCCAAATTTTCCGCTGATATATTCTTCAGTTTTAGTATTTTTAGGATTGAAGAATAATTCATCAGTTGAACTTTC
TTCTTCAATGCATCCATTAA

Product: gufA protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MIKSILDYLLTLHPVLLGLLGSTFTWFTTAFGAAAVFFFRKVDNKIMDAMLGFSAGIMIAASFFSLIQPAIERAEELGYI
TWVPAVFGFLVGAFFIYIVDVFVPDLDKLTFIDEDLTKHGKKDFLLFTAVTLHNFPEGLAVGVAFGALASNPDIQTLVGA
MLLTLGIGIQNIPEGAAISLPLRRGNVALAKCFNYGQMSGLVEIVGGLMGAYAVYSFTRILPFALAFSAGAMIYVSIEQL
IPEAKRKDIDNKVPSIFGVIGFTLMMFLDVSLG

Sequences:

>Translated_273_residues
MIKSILDYLLTLHPVLLGLLGSTFTWFTTAFGAAAVFFFRKVDNKIMDAMLGFSAGIMIAASFFSLIQPAIERAEELGYI
TWVPAVFGFLVGAFFIYIVDVFVPDLDKLTFIDEDLTKHGKKDFLLFTAVTLHNFPEGLAVGVAFGALASNPDIQTLVGA
MLLTLGIGIQNIPEGAAISLPLRRGNVALAKCFNYGQMSGLVEIVGGLMGAYAVYSFTRILPFALAFSAGAMIYVSIEQL
IPEAKRKDIDNKVPSIFGVIGFTLMMFLDVSLG
>Mature_273_residues
MIKSILDYLLTLHPVLLGLLGSTFTWFTTAFGAAAVFFFRKVDNKIMDAMLGFSAGIMIAASFFSLIQPAIERAEELGYI
TWVPAVFGFLVGAFFIYIVDVFVPDLDKLTFIDEDLTKHGKKDFLLFTAVTLHNFPEGLAVGVAFGALASNPDIQTLVGA
MLLTLGIGIQNIPEGAAISLPLRRGNVALAKCFNYGQMSGLVEIVGGLMGAYAVYSFTRILPFALAFSAGAMIYVSIEQL
IPEAKRKDIDNKVPSIFGVIGFTLMMFLDVSLG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577418, Length=329, Percent_Identity=34.6504559270517, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI229577422, Length=336, Percent_Identity=33.6309523809524, Blast_Score=147, Evalue=1e-35,
Organism=Escherichia coli, GI1789419, Length=249, Percent_Identity=28.1124497991968, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17507805, Length=320, Percent_Identity=39.6875, Blast_Score=197, Evalue=7e-51,
Organism=Drosophila melanogaster, GI24652846, Length=160, Percent_Identity=46.25, Blast_Score=130, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 29549; Mature: 29549

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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CCHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]