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The map label for this gene is gtaB [H]

Identifier: 15594552

GI number: 15594552

Start: 208706

End: 209542

Strand: Direct

Name: gtaB [H]

Synonym: BB0207

Alternate gene names: 15594552

Gene position: 208706-209542 (Clockwise)

Preceding gene: 15594550

Following gene: 15594553

Centisome position: 22.92

GC content: 28.32

Gene sequence:

>837_bases
ATGAAAGGCATTATTCTGGCAGCTGGGTATGGAACAAGATTTTTACCAATAACAAAAACAATTCCAAAAGAAATGCTACC
AATTTTAAACAAGCCAGCCATAGATTATATTATTCAAGAATTTATCGATTCAGGAATAAAAGATATTTTATTAATAAGCT
CAAGAAGAAAAAAAGTTCTTGAAGATTATTTTGACAGAGAAATTGAACTTGAAAATATTTTTTTAAAAGAAAATAAAAAA
GATGAATTAGAAAAGATTAGAAGCAAAAAAATCAACATAAGCTTCATAAGACAAAAAGAAATGCTAGGCACAGGAAATGC
CCTACTTTATGCAAAACCCTGGATAAATAGAGAGCCTGTAGTTGTAGCTTACCCTGACGATCTTTGCATTGGAAATCCAC
CATTAAGCTTGCAATTGATCAAACTTTATGAAAAAACTGGAAAGAACATAATATCTATCATTGAAAATCCAGAAAATATA
AATAGATACGGAGTAATAGATCTCTACAAAGACGAAATCCATGTAAAAAACATTATTGAAAAACCAAAGATTGGAAGTGA
GCCTAGCAATAAAGCATCTATTGGAAGATTTTTGTACAATTATGAGTTTTTTGAACATTTAGAAGAAGGATTCAAACTAC
ATAAAAAAGGTGAATACTATCACATTTATGCTTTAAAAAAGCTAATGGATCAAAAAAAAGTATTATATAAAAACATTGAA
GGGAAAAGAATTGACATAGGAACTCTTGAGGGTTATCTAGAGGCAATAATAAATTCTGCCAAAAAAGATAAAAAATTAAT
GGGAATTATCAAAAAAGGAATAAATGAAAACGATTAA

Upstream 100 bases:

>100_bases
CGAACTTACATACATAAATAAAAATTTTAAAACAATTTTAAAAAACAATGAATATATAAAATTAAATTTTTGCTATAATC
TTATTTTAAGAGAGAAAAAT

Downstream 100 bases:

>100_bases
AAAGGATTCAGAATTTTATGATTCCCTTGCCACATTAAAAAAGCATATAAACAAATATATAGAAGAAAAAGTTTTAAAAT
ATAGCATTTCTTCCCAGCTT

Product: UTP--glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKGIILAAGYGTRFLPITKTIPKEMLPILNKPAIDYIIQEFIDSGIKDILLISSRRKKVLEDYFDREIELENIFLKENKK
DELEKIRSKKINISFIRQKEMLGTGNALLYAKPWINREPVVVAYPDDLCIGNPPLSLQLIKLYEKTGKNIISIIENPENI
NRYGVIDLYKDEIHVKNIIEKPKIGSEPSNKASIGRFLYNYEFFEHLEEGFKLHKKGEYYHIYALKKLMDQKKVLYKNIE
GKRIDIGTLEGYLEAIINSAKKDKKLMGIIKKGINEND

Sequences:

>Translated_278_residues
MKGIILAAGYGTRFLPITKTIPKEMLPILNKPAIDYIIQEFIDSGIKDILLISSRRKKVLEDYFDREIELENIFLKENKK
DELEKIRSKKINISFIRQKEMLGTGNALLYAKPWINREPVVVAYPDDLCIGNPPLSLQLIKLYEKTGKNIISIIENPENI
NRYGVIDLYKDEIHVKNIIEKPKIGSEPSNKASIGRFLYNYEFFEHLEEGFKLHKKGEYYHIYALKKLMDQKKVLYKNIE
GKRIDIGTLEGYLEAIINSAKKDKKLMGIIKKGINEND
>Mature_278_residues
MKGIILAAGYGTRFLPITKTIPKEMLPILNKPAIDYIIQEFIDSGIKDILLISSRRKKVLEDYFDREIELENIFLKENKK
DELEKIRSKKINISFIRQKEMLGTGNALLYAKPWINREPVVVAYPDDLCIGNPPLSLQLIKLYEKTGKNIISIIENPENI
NRYGVIDLYKDEIHVKNIIEKPKIGSEPSNKASIGRFLYNYEFFEHLEEGFKLHKKGEYYHIYALKKLMDQKKVLYKNIE
GKRIDIGTLEGYLEAIINSAKKDKKLMGIIKKGINEND

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=210, Percent_Identity=25.7142857142857, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI11761619, Length=210, Percent_Identity=25.7142857142857, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787488, Length=273, Percent_Identity=32.967032967033, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788355, Length=292, Percent_Identity=30.8219178082192, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1790224, Length=261, Percent_Identity=27.9693486590038, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788351, Length=264, Percent_Identity=25.3787878787879, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI133931050, Length=210, Percent_Identity=25.2380952380952, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320148, Length=263, Percent_Identity=26.615969581749, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355443, Length=260, Percent_Identity=25.3846153846154, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24644084, Length=260, Percent_Identity=25.3846153846154, Blast_Score=81, Evalue=8e-16,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32221; Mature: 32221

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIILAAGYGTRFLPITKTIPKEMLPILNKPAIDYIIQEFIDSGIKDILLISSRRKKVL
CCCEEEECCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EDYFDREIELENIFLKENKKDELEKIRSKKINISFIRQKEMLGTGNALLYAKPWINREPV
HHHHCCEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEHHHHCCCCCEEEEECCCCCCCCE
VVAYPDDLCIGNPPLSLQLIKLYEKTGKNIISIIENPENINRYGVIDLYKDEIHVKNIIE
EEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEHHCCCCCCCCEEEEEEEHHHHHHHHHHC
KPKIGSEPSNKASIGRFLYNYEFFEHLEEGFKLHKKGEYYHIYALKKLMDQKKVLYKNIE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCC
GKRIDIGTLEGYLEAIINSAKKDKKLMGIIKKGINEND
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKGIILAAGYGTRFLPITKTIPKEMLPILNKPAIDYIIQEFIDSGIKDILLISSRRKKVL
CCCEEEECCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EDYFDREIELENIFLKENKKDELEKIRSKKINISFIRQKEMLGTGNALLYAKPWINREPV
HHHHCCEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEHHHHCCCCCEEEEECCCCCCCCE
VVAYPDDLCIGNPPLSLQLIKLYEKTGKNIISIIENPENINRYGVIDLYKDEIHVKNIIE
EEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEHHCCCCCCCCEEEEEEEHHHHHHHHHHC
KPKIGSEPSNKASIGRFLYNYEFFEHLEEGFKLHKKGEYYHIYALKKLMDQKKVLYKNIE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCC
GKRIDIGTLEGYLEAIINSAKKDKKLMGIIKKGINEND
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]